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Volumn 37, Issue 2, 2018, Pages 488-493

Protein intake distribution pattern does not affect anabolic response, lean body mass, muscle strength or function over 8 weeks in older adults: A randomized-controlled trial

Author keywords

Aging; Essential amino acids; Protein turnover; Sarcopenia; Stable isotope tracer

Indexed keywords

ADULT; AGED; ARTICLE; BODY COMPOSITION; BODY MASS; CONTROLLED STUDY; DIETARY INTAKE; FEMALE; FOOD PREFERENCE; GRIP STRENGTH; HUMAN; HUMAN EXPERIMENT; LEAN BODY WEIGHT; MALE; MUSCLE FUNCTION; MUSCLE STRENGTH; NORMAL HUMAN; PHYSICAL ACTIVITY; PROTEIN DEGRADATION; PROTEIN INTAKE; PROTEIN SYNTHESIS; RANDOMIZED CONTROLLED TRIAL; ADMINISTRATION AND DOSAGE; FEEDING BEHAVIOR; MEAL; MIDDLE AGED; PHYSIOLOGY;

EID: 85015321510     PISSN: 02615614     EISSN: 15321983     Source Type: Journal    
DOI: 10.1016/j.clnu.2017.02.020     Document Type: Article
Times cited : (60)

References (27)
  • 1
    • 53549110222 scopus 로고    scopus 로고
    • Optimal protein intake in the elderly
    • Wolfe, R.R., Miller, S.L., Miller, K.B., Optimal protein intake in the elderly. Clin Nutr 27 (2008), 675–684, 10.1016/j.clnu.2008.06.008.
    • (2008) Clin Nutr , vol.27 , pp. 675-684
    • Wolfe, R.R.1    Miller, S.L.2    Miller, K.B.3
  • 2
    • 43549097337 scopus 로고    scopus 로고
    • Current protein intake in America: analysis of the National Health and Nutrition Examination Survey, 2003-2004
    • Fulgoni, V.L., Current protein intake in America: analysis of the National Health and Nutrition Examination Survey, 2003-2004. Am J Clin Nutr 87 (2008), 1554S–1557S.
    • (2008) Am J Clin Nutr , vol.87 , pp. 1554S-1557S
    • Fulgoni, V.L.1
  • 3
    • 84901312383 scopus 로고    scopus 로고
    • Energy intake: percentages of energy from protein, carbohydrate, fat, and alcohol, by gender and age, what we eat in America, NHANES 2013-2014
    • Available from:
    • USDA Agricultural Research Service, Energy intake: percentages of energy from protein, carbohydrate, fat, and alcohol, by gender and age, what we eat in America, NHANES 2013-2014. 2016 Available from: www.ars.usda.gov.
    • (2016)
    • USDA Agricultural Research Service1
  • 4
    • 84891436659 scopus 로고    scopus 로고
    • Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise
    • Witard, O.C., Jackman, S.R., Breen, L., Smith, K., Selby, A., Tipton, K.D., Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise. Am J Clin Nutr 99 (2014), 86–95, 10.3945/ajcn.112.055517.
    • (2014) Am J Clin Nutr , vol.99 , pp. 86-95
    • Witard, O.C.1    Jackman, S.R.2    Breen, L.3    Smith, K.4    Selby, A.5    Tipton, K.D.6
  • 5
    • 84862175547 scopus 로고    scopus 로고
    • Myofibrillar protein synthesis following ingestion of soy protein isolate at rest and after resistance exercise in elderly men
    • Yang, Y., Churchward-Venne, T.A., Burd, N.A., Breen, L., Tarnopolsky, M.A., Phillips, S.M., Myofibrillar protein synthesis following ingestion of soy protein isolate at rest and after resistance exercise in elderly men. Nutr Metab (Lond), 9, 2012, 57, 10.1186/1743-7075-9-57.
    • (2012) Nutr Metab (Lond) , vol.9 , pp. 57
    • Yang, Y.1    Churchward-Venne, T.A.2    Burd, N.A.3    Breen, L.4    Tarnopolsky, M.A.5    Phillips, S.M.6
  • 6
    • 84870043638 scopus 로고    scopus 로고
    • Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men
    • Yang, Y., Breen, L., Burd, N.A., Hector, A.J., Churchward-Venne, T.A., Josse, A.R., et al. Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men. Br J Nutr 108 (2012), 1780–1788, 10.1017/S0007114511007422.
    • (2012) Br J Nutr , vol.108 , pp. 1780-1788
    • Yang, Y.1    Breen, L.2    Burd, N.A.3    Hector, A.J.4    Churchward-Venne, T.A.5    Josse, A.R.6
  • 7
    • 68849100887 scopus 로고    scopus 로고
    • A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects
    • Symons, T.B., Sheffield-Moore, M., Wolfe, R.R., Paddon-Jones, D., A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects. J Am Diet Assoc 109 (2009), 1582–1586, 10.1016/j.jada.2009.06.369.
    • (2009) J Am Diet Assoc , vol.109 , pp. 1582-1586
    • Symons, T.B.1    Sheffield-Moore, M.2    Wolfe, R.R.3    Paddon-Jones, D.4
  • 8
    • 84922419012 scopus 로고    scopus 로고
    • Protein ingestion to stimulate myofibrillar protein synthesis requires greater relative protein intakes in healthy older versus younger men
    • Moore, D.R., Churchward-Venne, T.A., Witard, O., Breen, L., Burd, N.A., Tipton, K.D., et al. Protein ingestion to stimulate myofibrillar protein synthesis requires greater relative protein intakes in healthy older versus younger men. J Gerontol A Biol Sci Med Sci 70 (2015), 57–62, 10.1093/gerona/glu103.
    • (2015) J Gerontol A Biol Sci Med Sci , vol.70 , pp. 57-62
    • Moore, D.R.1    Churchward-Venne, T.A.2    Witard, O.3    Breen, L.4    Burd, N.A.5    Tipton, K.D.6
  • 9
    • 58149133630 scopus 로고    scopus 로고
    • Dietary protein recommendations and the prevention of sarcopenia
    • Paddon-Jones, D., Rasmussen, B.B., Dietary protein recommendations and the prevention of sarcopenia. Curr Opin Clin Nutr Metab Care 12 (2009), 86–90, 10.1097/MCO.0b013e32831cef8b.
    • (2009) Curr Opin Clin Nutr Metab Care , vol.12 , pp. 86-90
    • Paddon-Jones, D.1    Rasmussen, B.B.2
  • 10
    • 84919416173 scopus 로고    scopus 로고
    • Quantity of dietary protein intake, but not pattern of intake, affects net protein balance primarily through differences in protein synthesis in older adults
    • Kim, I.-Y., Schutzler, S., Schrader, A., Spencer, H., Kortebein, P., Deutz, N.E.P., et al. Quantity of dietary protein intake, but not pattern of intake, affects net protein balance primarily through differences in protein synthesis in older adults. Am J Physiol Endocrinol Metab 308 (2015), E21–E28, 10.1152/ajpendo.00382.2014.
    • (2015) Am J Physiol Endocrinol Metab , vol.308 , pp. E21-E28
    • Kim, I.-Y.1    Schutzler, S.2    Schrader, A.3    Spencer, H.4    Kortebein, P.5    Deutz, N.E.P.6
  • 11
    • 84929692682 scopus 로고    scopus 로고
    • Hypoenergetic diet-induced reductions in myofibrillar protein synthesis are restored with resistance training and balanced daily protein ingestion in older men
    • Murphy, C.H., Churchward-Venne, T.A., Mitchell, C.J., Kolar, N.M., Kassis, A., Karagounis, L.G., et al. Hypoenergetic diet-induced reductions in myofibrillar protein synthesis are restored with resistance training and balanced daily protein ingestion in older men. Am J Physiol Endocrinol Metab 308 (2015), E734–E743, 10.1152/ajpendo.00550.2014.
    • (2015) Am J Physiol Endocrinol Metab , vol.308 , pp. E734-E743
    • Murphy, C.H.1    Churchward-Venne, T.A.2    Mitchell, C.J.3    Kolar, N.M.4    Kassis, A.5    Karagounis, L.G.6
  • 12
    • 84896129645 scopus 로고    scopus 로고
    • Acute post-exercise myofibrillar protein synthesis is not correlated with resistance training-induced muscle hypertrophy in young men
    • Mitchell, C.J., Churchward-Venne, T.A., Parise, G., Bellamy, L., Baker, S.K., Smith, K., et al. Acute post-exercise myofibrillar protein synthesis is not correlated with resistance training-induced muscle hypertrophy in young men. PLoS One, 9, 2014, e89431, 10.1371/journal.pone.0089431.
    • (2014) PLoS One , vol.9 , pp. e89431
    • Mitchell, C.J.1    Churchward-Venne, T.A.2    Parise, G.3    Bellamy, L.4    Baker, S.K.5    Smith, K.6
  • 13
    • 41349103398 scopus 로고    scopus 로고
    • Effect of amino acid supplementation on muscle mass, strength and physical function in elderly
    • Borsheim, E., Bui, Q.-U.T., Tissier, S., Kobayashi, H., Ferrando, A.A., Wolfe, R.R., Effect of amino acid supplementation on muscle mass, strength and physical function in elderly. Clin Nutr 27 (2008), 189–195, 10.1016/j.clnu.2008.01.001.
    • (2008) Clin Nutr , vol.27 , pp. 189-195
    • Borsheim, E.1    Bui, Q.-U.T.2    Tissier, S.3    Kobayashi, H.4    Ferrando, A.A.5    Wolfe, R.R.6
  • 14
    • 75949099307 scopus 로고    scopus 로고
    • EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly
    • Ferrando, A.A., Paddon-Jones, D., Hays, N.P., Kortebein, P., Ronsen, O., Williams, R.H., et al. EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly. Clin Nutr 29 (2010), 18–23, 10.1016/j.clnu.2009.03.009.
    • (2010) Clin Nutr , vol.29 , pp. 18-23
    • Ferrando, A.A.1    Paddon-Jones, D.2    Hays, N.P.3    Kortebein, P.4    Ronsen, O.5    Williams, R.H.6
  • 15
    • 0019458610 scopus 로고
    • Use of a heated superficial hand vein as an alternative site for the measurement of amino acid concentrations and for the study of glucose and alanine kinetics in man
    • Abumrad, N.N., Rabin, D., Diamond, M.P., Lacy, W.W., Use of a heated superficial hand vein as an alternative site for the measurement of amino acid concentrations and for the study of glucose and alanine kinetics in man. Metab Clin Exp 30 (1981), 936–940.
    • (1981) Metab Clin Exp , vol.30 , pp. 936-940
    • Abumrad, N.N.1    Rabin, D.2    Diamond, M.P.3    Lacy, W.W.4
  • 16
    • 84949551114 scopus 로고    scopus 로고
    • The anabolic response to a meal containing different amounts of protein is not limited by the maximal stimulation of protein synthesis in healthy young adults
    • Kim, I.-Y., Schutzler, S., Schrader, A., Spencer, H.J., Azhar, G., Ferrando, A.A., et al. The anabolic response to a meal containing different amounts of protein is not limited by the maximal stimulation of protein synthesis in healthy young adults. Am J Physiol Endocrinol Metab 310 (2016), E73–E80, 10.1152/ajpendo.00365.2015.
    • (2016) Am J Physiol Endocrinol Metab , vol.310 , pp. E73-E80
    • Kim, I.-Y.1    Schutzler, S.2    Schrader, A.3    Spencer, H.J.4    Azhar, G.5    Ferrando, A.A.6
  • 17
    • 0032835655 scopus 로고    scopus 로고
    • Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extraction
    • Volpi, E., Mittendorfer, B., Wolf, S.E., Wolfe, R.R., Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extraction., 277, 1999, E513–E520.
    • (1999) , vol.277 , pp. E513-E520
    • Volpi, E.1    Mittendorfer, B.2    Wolf, S.E.3    Wolfe, R.R.4
  • 18
    • 0036790054 scopus 로고    scopus 로고
    • Regulation of muscle protein by amino acids
    • Wolfe, R.R., Regulation of muscle protein by amino acids. J Nutr 132 (2002), 3219S–3224S.
    • (2002) J Nutr , vol.132 , pp. 3219S-3224S
    • Wolfe, R.R.1
  • 19
    • 84901306295 scopus 로고    scopus 로고
    • Dietary protein distribution positively influences 24-h muscle protein synthesis in healthy adults
    • Mamerow, M.M., Mettler, J.A., English, K.L., Casperson, S.L., Arentson-Lantz, E., Sheffield-Moore, M., et al. Dietary protein distribution positively influences 24-h muscle protein synthesis in healthy adults. J Nutr 144 (2014), 876–880, 10.3945/jn.113.185280.
    • (2014) J Nutr , vol.144 , pp. 876-880
    • Mamerow, M.M.1    Mettler, J.A.2    English, K.L.3    Casperson, S.L.4    Arentson-Lantz, E.5    Sheffield-Moore, M.6
  • 20
    • 84880192503 scopus 로고    scopus 로고
    • Anabolic resistance of muscle protein synthesis with aging
    • Burd, N.A., Gorissen, S.H., van Loon, L.J.C., Anabolic resistance of muscle protein synthesis with aging. Exerc Sport Sci Rev 41 (2013), 169–173, 10.1097/JES.0b013e318292f3d5.
    • (2013) Exerc Sport Sci Rev , vol.41 , pp. 169-173
    • Burd, N.A.1    Gorissen, S.H.2    van Loon, L.J.C.3
  • 21
    • 31544482447 scopus 로고    scopus 로고
    • Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids
    • Katsanos, C.S., Kobayashi, H., Sheffield-Moore, M., Aarsland, A., Wolfe, R.R., Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids. Am J Clin Nutr 82 (2005), 1065–1073.
    • (2005) Am J Clin Nutr , vol.82 , pp. 1065-1073
    • Katsanos, C.S.1    Kobayashi, H.2    Sheffield-Moore, M.3    Aarsland, A.4    Wolfe, R.R.5
  • 22
    • 58149389265 scopus 로고    scopus 로고
    • Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men
    • Moore, D.R., Robinson, M.J., Fry, J.L., Tang, J.E., Glover, E.I., Wilkinson, S.B., et al. Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men. Am J Clin Nutr 89 (2009), 161–168, 10.3945/ajcn.2008.26401.
    • (2009) Am J Clin Nutr , vol.89 , pp. 161-168
    • Moore, D.R.1    Robinson, M.J.2    Fry, J.L.3    Tang, J.E.4    Glover, E.I.5    Wilkinson, S.B.6
  • 23
    • 84963569503 scopus 로고    scopus 로고
    • Per meal dose and frequency of protein consumption is associated with lean mass and muscle performance
    • Loenneke, J.P., Loprinzi, P.D., Murphy, C.H., Phillips, S.M., Per meal dose and frequency of protein consumption is associated with lean mass and muscle performance. Clin Nutr 35:6 (2016), 1506–1511, 10.1016/j.clnu.2016.04.002.
    • (2016) Clin Nutr , vol.35 , Issue.6 , pp. 1506-1511
    • Loenneke, J.P.1    Loprinzi, P.D.2    Murphy, C.H.3    Phillips, S.M.4
  • 24
    • 84984710656 scopus 로고    scopus 로고
    • Sexual dimorphism in skeletal muscle protein turnover
    • Smith, G.I., Mittendorfer, B., Sexual dimorphism in skeletal muscle protein turnover. J Appl Physiol 120 (2016), 674–682, 10.1152/japplphysiol.00625.2015.
    • (2016) J Appl Physiol , vol.120 , pp. 674-682
    • Smith, G.I.1    Mittendorfer, B.2
  • 25
    • 66149141889 scopus 로고    scopus 로고
    • Amino acid supplementation increases lean body mass, basal muscle protein synthesis, and insulin-like growth factor-I expression in older women
    • Dillon, E.L., Sheffield-Moore, M., Paddon-Jones, D., Gilkison, C., Sanford, A.P., Casperson, S.L., et al. Amino acid supplementation increases lean body mass, basal muscle protein synthesis, and insulin-like growth factor-I expression in older women. J Clin Endocrinol Metab 94 (2009), 1630–1637, 10.1210/jc.2008-1564.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 1630-1637
    • Dillon, E.L.1    Sheffield-Moore, M.2    Paddon-Jones, D.3    Gilkison, C.4    Sanford, A.P.5    Casperson, S.L.6
  • 26
    • 0032080924 scopus 로고    scopus 로고
    • Exogenous amino acids stimulate net muscle protein synthesis in the elderly
    • Volpi, E., Ferrando, A.A., Yeckel, C.W., Tipton, K.D., Wolfe, R.R., Exogenous amino acids stimulate net muscle protein synthesis in the elderly. J Clin Investig 101 (1998), 2000–2007, 10.1172/JCI939.
    • (1998) J Clin Investig , vol.101 , pp. 2000-2007
    • Volpi, E.1    Ferrando, A.A.2    Yeckel, C.W.3    Tipton, K.D.4    Wolfe, R.R.5
  • 27
    • 0028837394 scopus 로고
    • Physiologic hyperinsulinemia stimulates protein synthesis and enhances transport of selected amino acids in human skeletal muscle
    • Biolo, G., Declan Fleming, R.Y., Wolfe, R.R., Physiologic hyperinsulinemia stimulates protein synthesis and enhances transport of selected amino acids in human skeletal muscle. J Clin Investig 95 (1995), 811–819, 10.1172/JCI117731.
    • (1995) J Clin Investig , vol.95 , pp. 811-819
    • Biolo, G.1    Declan Fleming, R.Y.2    Wolfe, R.R.3


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