메뉴 건너뛰기




Volumn 48, Issue 4, 2017, Pages 1061-1069

Targeting Different Monocyte/Macrophage Subsets Has No Impact on Outcome in Experimental Stroke

Author keywords

Animal; Inflammation; Macrophages; Models; Monocytes; Stroke

Indexed keywords

CHEMOKINE RECEPTOR CCR2 ANTAGONIST; CLODRONIC ACID; MC 21 ANTIBODY; UNCLASSIFIED DRUG;

EID: 85015253564     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.116.015577     Document Type: Article
Times cited : (44)

References (38)
  • 1
    • 79960141471 scopus 로고    scopus 로고
    • The immunology of stroke: From mechanisms to translation
    • Iadecola C, Anrather J. The immunology of stroke: from mechanisms to translation. Nat Med. 2011;17:796-808. doi: 10.1038/nm.2399.
    • (2011) Nat Med , vol.17 , pp. 796-808
    • Iadecola, C.1    Anrather, J.2
  • 3
    • 65549130913 scopus 로고    scopus 로고
    • Temporal and spatial dynamics of cerebral immune cell accumulation in stroke
    • Gelderblom M, Leypoldt F, Steinbach K, Behrens D, Choe CU, Siler DA, et al. Temporal and spatial dynamics of cerebral immune cell accumulation in stroke. Stroke. 2009;40:1849-1857. doi: 10.1161/STROKEAHA.108.534503.
    • (2009) Stroke , vol.40 , pp. 1849-1857
    • Gelderblom, M.1    Leypoldt, F.2    Steinbach, K.3    Behrens, D.4    Choe, C.U.5    Siler, D.A.6
  • 4
    • 79952175153 scopus 로고    scopus 로고
    • Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke
    • Liesz A, Zhou W, Mracskó É, Karcher S, Bauer H, Schwarting S, et al. Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke. Brain. 2011;134(pt 3):704-720. doi: 10.1093/brain/awr008.
    • (2011) Brain , vol.134 , pp. 704-720
    • Liesz, A.1    Zhou, W.2    Mracskó, É.3    Karcher, S.4    Bauer, H.5    Schwarting, S.6
  • 5
    • 84923261298 scopus 로고    scopus 로고
    • Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke
    • Neumann J, Riek-Burchardt M, Herz J, Doeppner TR, König R, Hütten H, et al. Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke. Acta Neuropathol. 2015;129:259-277. doi: 10.1007/s00401-014-1355-2.
    • (2015) Acta Neuropathol , vol.129 , pp. 259-277
    • Neumann, J.1    Riek-Burchardt, M.2    Herz, J.3    Doeppner, T.R.4    König, R.5    Hütten, H.6
  • 6
    • 68349160698 scopus 로고    scopus 로고
    • Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury
    • Shichita T, Sugiyama Y, Ooboshi H, Sugimori H, Nakagawa R, Takada I, et al. Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury. Nat Med. 2009;15:946-950. doi: 10.1038/nm.1999.
    • (2009) Nat Med , vol.15 , pp. 946-950
    • Shichita, T.1    Sugiyama, Y.2    Ooboshi, H.3    Sugimori, H.4    Nakagawa, R.5    Takada, I.6
  • 8
    • 70350558453 scopus 로고    scopus 로고
    • Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord
    • Kigerl KA, Gensel JC, Ankeny DP, Alexander JK, Donnelly DJ, Popovich PG. Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. J Neurosci. 2009;29:13435-13444. doi: 10.1523/JNEUROSCI.3257-09.2009.
    • (2009) J Neurosci , vol.29 , pp. 13435-13444
    • Kigerl, K.A.1    Gensel, J.C.2    Ankeny, D.P.3    Alexander, J.K.4    Donnelly, D.J.5    Popovich, P.G.6
  • 9
    • 84901056045 scopus 로고    scopus 로고
    • Ly-6Chigh monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium
    • Hilgendorf I, Gerhardt LM, Tan TC, Winter C, Holderried TA, Chousterman BG, et al. Ly-6Chigh monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium. Circ Res. 2014;114:1611-1622. doi: 10.1161/CIRCRESAHA.114.303204.
    • (2014) Circ Res , vol.114 , pp. 1611-1622
    • Hilgendorf, I.1    Gerhardt, L.M.2    Tan, T.C.3    Winter, C.4    Holderried, T.A.5    Chousterman, B.G.6
  • 10
    • 77953350982 scopus 로고    scopus 로고
    • Monocytes: Protagonists of infarct inflammation and repair after myocardial infarction
    • Nahrendorf M, Pittet MJ, Swirski FK. Monocytes: protagonists of infarct inflammation and repair after myocardial infarction. Circulation. 2010;121:2437-2445. doi: 10.1161/CIRCULATIONAHA. 109.916346.
    • (2010) Circulation , vol.121 , pp. 2437-2445
    • Nahrendorf, M.1    Pittet, M.J.2    Swirski, F.K.3
  • 11
    • 36549033197 scopus 로고    scopus 로고
    • The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
    • Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL, et al. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med. 2007;204:3037-3047. doi: 10.1084/jem.20070885.
    • (2007) J Exp Med , vol.204 , pp. 3037-3047
    • Nahrendorf, M.1    Swirski, F.K.2    Aikawa, E.3    Stangenberg, L.4    Wurdinger, T.5    Figueiredo, J.L.6
  • 12
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol. 2008;8:958-969. doi: 10.1038/nri2448.
    • (2008) Nat Rev Immunol. , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 13
    • 68049143269 scopus 로고    scopus 로고
    • Infiltrating blood-derived macrophages are vital cells playing an antiinflammatory role in recovery from spinal cord injury in mice
    • Shechter R, London A, Varol C, Raposo C, Cusimano M, Yovel G, et al. Infiltrating blood-derived macrophages are vital cells playing an antiinflammatory role in recovery from spinal cord injury in mice. PLoS Med. 2009;6:e1000113. doi: 10.1371/journal.pmed.1000113.
    • (2009) PLoS Med , vol.6 , pp. e1000113
    • Shechter, R.1    London, A.2    Varol, C.3    Raposo, C.4    Cusimano, M.5    Yovel, G.6
  • 14
    • 34247849521 scopus 로고    scopus 로고
    • Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice
    • van Amerongen MJ, Harmsen MC, van Rooijen N, Petersen AH, van Luyn MJ. Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice. Am J Pathol. 2007;170:818-829. doi: 10.2353/ajpath.2007.060547.
    • (2007) Am J Pathol , vol.170 , pp. 818-829
    • Van Amerongen, M.J.1    Harmsen, M.C.2    Van Rooijen, N.3    Petersen, A.H.4    Van Luyn, M.J.5
  • 15
    • 69749101241 scopus 로고    scopus 로고
    • Turnover of meningeal and perivascular macrophages in the brain of MCP-1-CCR-2-or double knockout mice
    • Schilling M, Strecker JK, Ringelstein EB, Kiefer R, Schäbitz WR. Turnover of meningeal and perivascular macrophages in the brain of MCP-1-, CCR-2-or double knockout mice. Exp Neurol. 2009;219:583-585. doi: 10.1016/j.expneurol.2009.07.003.
    • (2009) Exp Neurol , vol.219 , pp. 583-585
    • Schilling, M.1    Strecker, J.K.2    Ringelstein, E.B.3    Kiefer, R.4    Schäbitz, W.R.5
  • 16
    • 84941105913 scopus 로고    scopus 로고
    • Evidence that Ly6C(hi) monocytes are protective in acute ischemic stroke by promoting M2 macrophage polarization
    • Chu HX, Broughton BR, Kim HA, Lee S, Drummond GR, Sobey CG. Evidence that Ly6C(hi) monocytes are protective in acute ischemic stroke by promoting M2 macrophage polarization. Stroke. 2015;46:1929-1937. doi: 10.1161/STROKEAHA.115.009426.
    • (2015) Stroke , vol.46 , pp. 1929-1937
    • Chu, H.X.1    Broughton, B.R.2    Kim, H.A.3    Lee, S.4    Drummond, G.R.5    Sobey, C.G.6
  • 17
    • 84879373117 scopus 로고    scopus 로고
    • In vitro and in vivo models of cerebral ischemia show discrepancy in therapeutic effects of M2 macrophages
    • Desestret V, Riou A, Chauveau F, Cho TH, Devillard E, Marinescu M, et al. In vitro and in vivo models of cerebral ischemia show discrepancy in therapeutic effects of M2 macrophages. PLoS One. 2013;8:e67063. doi: 10.1371/journal.pone.0067063.
    • (2013) PLoS One , vol.8 , pp. e67063
    • Desestret, V.1    Riou, A.2    Chauveau, F.3    Cho, T.H.4    Devillard, E.5    Marinescu, M.6
  • 18
    • 0024394044 scopus 로고
    • Macrophage colony-stimulating factor (rMCSF) stimulates pinocytosis in bone marrow-derived macrophages
    • Racoosin EL, Swanson JA. Macrophage colony-stimulating factor (rMCSF) stimulates pinocytosis in bone marrow-derived macrophages. J Exp Med. 1989;170:1635-1648.
    • (1989) J Exp Med , vol.170 , pp. 1635-1648
    • Racoosin, E.L.1    Swanson, J.A.2
  • 19
    • 84860623244 scopus 로고    scopus 로고
    • Licensing of myeloid cells promotes central nervous system autoimmunity and is controlled by peroxisome proliferator-activated receptor
    • Hucke S, Flodorf J, Grützke B, Dunay IR, Frenzel K, Jungverdorben J, et al. Licensing of myeloid cells promotes central nervous system autoimmunity and is controlled by peroxisome proliferator-activated receptor . Brain. 2012;135(pt 5):1586-1605. doi: 10.1093/brain/aws058.
    • (2012) Brain , vol.135 , pp. 1586-1605
    • Hucke, S.1    Flodorf, J.2    Grützke, B.3    Dunay, I.R.4    Frenzel, K.5    Jungverdorben, J.6
  • 20
    • 0026795049 scopus 로고
    • Middle cerebral artery occlusion in rats: A neurological and pathological evaluation of a reproducible model
    • discussion 106
    • Menzies SA, Hoff JT, Betz AL. Middle cerebral artery occlusion in rats: a neurological and pathological evaluation of a reproducible model. Neurosurgery. 1992;31:100-106, discussion 106.
    • (1992) Neurosurgery , vol.31 , pp. 100-106
    • Menzies, S.A.1    Hoff, J.T.2    Betz, A.L.3
  • 21
    • 84892188651 scopus 로고    scopus 로고
    • Bone marrow-derived mononuclear cells do not exert acute neuroprotection after stroke in spontaneously hypertensive rats
    • Minnerup J, Wagner DC, Strecker JK, Pösel C, Sevimli-Abdis S, Schmidt A, et al. Bone marrow-derived mononuclear cells do not exert acute neuroprotection after stroke in spontaneously hypertensive rats. Front Cell Neurosci. 2014;7:288. doi: 10.3389/fncel.2013.00288.
    • (2014) Front Cell Neurosci , vol.7 , pp. 288
    • Minnerup, J.1    Wagner, D.C.2    Strecker, J.K.3    Pösel, C.4    Sevimli-Abdis, S.5    Schmidt, A.6
  • 22
    • 0035313220 scopus 로고    scopus 로고
    • Expression and characterization of the chemokine receptors CCR2 and CCR5 in mice
    • Mack M, Cihak J, Simonis C, Luckow B, Proudfoot AE, Plachý J, et al. Expression and characterization of the chemokine receptors CCR2 and CCR5 in mice. J Immunol. 2001;166:4697-4704.
    • (2001) J Immunol , vol.166 , pp. 4697-4704
    • MacK, M.1    Cihak, J.2    Simonis, C.3    Luckow, B.4    Proudfoot, A.E.5    Plachý, J.6
  • 23
    • 79958256926 scopus 로고    scopus 로고
    • Effects of neural progenitor cells on sensorimotor recovery and endogenous repair mechanisms after photothrombotic stroke
    • Minnerup J, Kim JB, Schmidt A, Diederich K, Bauer H, Schilling M, et al. Effects of neural progenitor cells on sensorimotor recovery and endogenous repair mechanisms after photothrombotic stroke. Stroke. 2011;42:1757-1763. doi: 10.1161/STROKEAHA.110.599282.
    • (2011) Stroke , vol.42 , pp. 1757-1763
    • Minnerup, J.1    Kim, J.B.2    Schmidt, A.3    Diederich, K.4    Bauer, H.5    Schilling, M.6
  • 24
    • 78149431325 scopus 로고    scopus 로고
    • Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke
    • Clarkson AN, Huang BS, Macisaac SE, Mody I, Carmichael ST. Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke. Nature. 2010;468:305-309. doi: 10.1038/nature09511.
    • (2010) Nature , vol.468 , pp. 305-309
    • Clarkson, A.N.1    Huang, B.S.2    MacIsaac, S.E.3    Mody, I.4    Carmichael, S.T.5
  • 25
    • 1842405434 scopus 로고    scopus 로고
    • Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro
    • Frith JC, Mönkkönen J, Blackburn GM, Russell RG, Rogers MJ. Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro. J Bone Miner Res. 1997;12:1358-1367. doi: 10.1359/jbmr.1997.12.9.1358.
    • (1997) J Bone Miner Res , vol.12 , pp. 1358-1367
    • Frith, J.C.1    Mönkkönen, J.2    Blackburn, G.M.3    Russell, R.G.4    Rogers, M.J.5
  • 26
    • 84959544592 scopus 로고    scopus 로고
    • Combining growth factor and bone marrow cell therapy induces bleeding and alters immune response after stroke in mice
    • Strecker JK, Olk J, Hoppen M, Gess B, Diederich K, Schmidt A, et al. Combining growth factor and bone marrow cell therapy induces bleeding and alters immune response after stroke in mice. Stroke. 2016;47:852-862. doi: 10.1161/STROKEAHA.115.011230.
    • (2016) Stroke , vol.47 , pp. 852-862
    • Strecker, J.K.1    Olk, J.2    Hoppen, M.3    Gess, B.4    Diederich, K.5    Schmidt, A.6
  • 29
    • 84872706357 scopus 로고    scopus 로고
    • Review: Activation patterns of microglia and their identification in the human brain
    • Boche D, Perry VH, Nicoll JA. Review: activation patterns of microglia and their identification in the human brain. Neuropathol Appl Neurobiol. 2013;39:3-18. doi: 10.1111/nan.12011.
    • (2013) Neuropathol Appl Neurobiol , vol.39 , pp. 3-18
    • Boche, D.1    Perry, V.H.2    Nicoll, J.A.3
  • 31
    • 84959527149 scopus 로고    scopus 로고
    • Immature monocytes recruited to the ischemic mouse brain differentiate into macrophages with features of alternative activation
    • Miró-Mur F, Pérez-de-Puig I, Ferrer-Ferrer M, Urra X, Justicia C, Chamorro A, et al. Immature monocytes recruited to the ischemic mouse brain differentiate into macrophages with features of alternative activation. Brain Behav Immun. 2016;53:18-33. doi: 10.1016/j.bbi.2015.08.010.
    • (2016) Brain Behav Immun , vol.53 , pp. 18-33
    • Miró-Mur, F.1    Pérez-De-Puig, I.2    Ferrer-Ferrer, M.3    Urra, X.4    Justicia, C.5    Chamorro, A.6
  • 33
    • 84920973617 scopus 로고    scopus 로고
    • The role of microglia and myeloid immune cells in acute cerebral ischemia
    • Benakis C, Garcia-Bonilla L, Iadecola C, Anrather J. The role of microglia and myeloid immune cells in acute cerebral ischemia. Front Cell Neurosci. 2014;8:461. doi: 10.3389/fncel.2014.00461.
    • (2014) Front Cell Neurosci , vol.8 , pp. 461
    • Benakis, C.1    Garcia-Bonilla, L.2    Iadecola, C.3    Anrather, J.4
  • 34
    • 84957638056 scopus 로고    scopus 로고
    • Macrophage depletion reduced brain injury following middle cerebral artery occlusion in mice
    • Ma Y, Li Y, Jiang L, Wang L, Jiang Z, Wang Y, et al. Macrophage depletion reduced brain injury following middle cerebral artery occlusion in mice. J Neuroinflammation. 2016;13:38. doi: 10.1186/s12974-016-0504-z.
    • (2016) J Neuroinflammation , vol.13 , pp. 38
    • Ma, Y.1    Li, Y.2    Jiang, L.3    Wang, L.4    Jiang, Z.5    Wang, Y.6
  • 35
    • 84991607728 scopus 로고    scopus 로고
    • Macrophages are essential for maintaining a M2 protective response early after ischemic brain injury
    • Perego C, Fumagalli S, Zanier ER, Carlino E, Panini N, Erba E, et al. Macrophages are essential for maintaining a M2 protective response early after ischemic brain injury. Neurobiol Dis. 2016;96:284-293. doi: 10.1016/j.nbd.2016.09.017.
    • (2016) Neurobiol Dis , vol.96 , pp. 284-293
    • Perego, C.1    Fumagalli, S.2    Zanier, E.R.3    Carlino, E.4    Panini, N.5    Erba, E.6
  • 36
    • 68649107955 scopus 로고    scopus 로고
    • The role of CC chemokine receptor 2 on microglia activation and bloodborne cell recruitment after transient focal cerebral ischemia in mice
    • Schilling M, Strecker JK, Ringelstein EB, Schäbitz WR, Kiefer R. The role of CC chemokine receptor 2 on microglia activation and bloodborne cell recruitment after transient focal cerebral ischemia in mice. Brain Res. 2009;1289:79-84. doi: 10.1016/j.brainres.2009.06.054.
    • (2009) Brain Res , vol.1289 , pp. 79-84
    • Schilling, M.1    Strecker, J.K.2    Ringelstein, E.B.3    Schäbitz, W.R.4    Kiefer, R.5
  • 37
    • 34247874753 scopus 로고    scopus 로고
    • Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice
    • Dimitrijevic OB, Stamatovic SM, Keep RF, Andjelkovic AV. Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice. Stroke. 2007;38:1345-1353. doi: 10.1161/01. STR.0000259709.16654.8f.
    • (2007) Stroke , vol.38 , pp. 1345-1353
    • Dimitrijevic, O.B.1    Stamatovic, S.M.2    Keep, R.F.3    Andjelkovic, A.V.4
  • 38
    • 84963762637 scopus 로고    scopus 로고
    • Monocyte-derived macrophages contribute to spontaneous long-term functional recovery after stroke in mice
    • Wattananit S, Tornero D, Graubardt N, Memanishvili T, Monni E, Tatarishvili J, et al. Monocyte-derived macrophages contribute to spontaneous long-term functional recovery after stroke in mice. J Neurosci. 2016;36:4182-4195. doi: 10.1523/JNEUROSCI.4317-15.2016.
    • (2016) J Neurosci , vol.36 , pp. 4182-4195
    • Wattananit, S.1    Tornero, D.2    Graubardt, N.3    Memanishvili, T.4    Monni, E.5    Tatarishvili, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.