Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk

Nature Immunology

Volumn 18, Issue 5, 2017, Pages 530-540

  Piccolo, Viviana ^a   Curina, Alessia ^a   Genua, Marco ^b   Ghisletti, Serena ^c   Simonatto, Marta ^c   Sabò, Arianna ^d   Amati, Bruno ^a,d   Ostuni, Renato ^b   Natoli, Gioacchino ^a,e  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^b SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^c HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^d ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^e HUMANITAS UNIVERSITY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR; CCAAT ENHANCER BINDING PROTEIN BETA; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 27; LONG CHAIN FATTY ACID COENZYME A LIGASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; MONOCYTE CHEMOTACTIC PROTEIN 5; MYC PROTEIN; PROGRAMMED DEATH 1 LIGAND 1; RANTES; RECOMBINANT GAMMA INTERFERON; RECOMBINANT INTERLEUKIN 4; STAT1 PROTEIN; STAT6 PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR JUNB; TRANSCRIPTION FACTOR MAF; VASCULOTROPIN RECEPTOR 1; GAMMA INTERFERON; INTERLEUKIN 4; IRF1 PROTEIN, MOUSE; MYC PROTEIN, MOUSE; SMALL INTERFERING RNA; STAT1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; BONE MARROW DERIVED MACROPHAGE; CELL PLASTICITY; CONTROLLED STUDY; DNA SEQUENCE; E BOX ELEMENT; ENHANCER REGION; EPIGENETICS; GENOMICS; HISTONE ACETYLATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; CELL DIFFERENTIATION; CELL LINE; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; HUMAN; INBRED MOUSE STRAIN; MACROPHAGE; METABOLISM; PHYSIOLOGY; TRANSCRIPTION INITIATION;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HUMANS; INTERFERON REGULATORY FACTOR-1; INTERFERON-GAMMA; INTERLEUKIN-4; MACROPHAGES; MICE; MICE, INBRED STRAINS; PROTO-ONCOGENE PROTEINS C-MYC; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTIONAL ACTIVATION;

EID: 85015062618     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3710     Document Type: Article

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