Helminth infection reactivates latent γ-herpesvirus via cytokine competition at a viral promoter

Science

Volumn 345, Issue 6196, 2014, Pages 573-577

  Reese, T A ^a   Wakeman, B S ^b   Choi, H S ^c   Hufford, M M ^d   Huang, S C ^a   Zhang, X ^a   Buck, M D ^a   Jezewski, A ^a   Kambal, A ^a   Liu, C Y ^a   Goel, G ^e   Murray, P J ^f   Xavier, R J ^e   Kaplan, M H ^d   Renne, R ^c   Speck, S H ^b   Artyomov, M N ^a   Pearce, E J ^a   Virgin, H W ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE 1; ETOMOXIR; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 13; INTERLEUKIN 4; PEROXISOME PROLIFERATOR; STAT1 PROTEIN; STAT6 PROTEIN; STAT6 PROTEIN, MOUSE;

IMMUNE SYSTEM; INFECTIOUS DISEASE; PATHOGEN;

ANIMAL MODEL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; DISEASE ASSOCIATION; DRUG EFFECT; FATTY ACID OXIDATION; GAMMAHERPESVIRINAE; HELMINTHIASIS; HERPES VIRUS; HERPES VIRUS INFECTION; HUMAN; IMMUNE STATUS; IN VIVO STUDY; KAPOSI SARCOMA; LATENT PERIOD; LATENT VIRUS INFECTION; MACROPHAGE FUNCTION; MOUSE; MURINAE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; VIRUS REACTIVATION; VIRUS REPLICATION; VIRUS TRANSCRIPTION; ANIMAL; C57BL MOUSE; GENE EXPRESSION REGULATION; GENETICS; HELIGMOSOMOIDES POLYGYRUS; HUMAN HERPESVIRUS 8; IMMUNOLOGY; MACROPHAGE; METABOLISM; OOCYTE; PHYSIOLOGY; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; STRONGYLE INFECTION; VIRUS ACTIVATION; VIRUS LATENCY;

ANIMALS; GAMMAHERPESVIRINAE; GENE EXPRESSION REGULATION, VIRAL; HERPESVIRUS 8, HUMAN; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-4; MACROPHAGES; MICE; MICE, INBRED C57BL; NEMATOSPIROIDES DUBIUS; OVUM; PROMOTER REGIONS, GENETIC; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; STAT6 TRANSCRIPTION FACTOR; STRONGYLIDA INFECTIONS; VIRUS ACTIVATION; VIRUS LATENCY; VIRUS REPLICATION;

EID: 84905918361     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1254517     Document Type: Article

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