Resveratrol protects against spinal cord injury by activating autophagy and inhibiting apoptosis mediated by the SIRT1/AMPK signaling pathway

Neuroscience

Volumn 348, Issue , 2017, Pages 241-251

  Zhao, Haosen ^a   Chen, Shurui ^a   Gao, Kai ^b   Zhou, Zipeng ^a   Wang, Chen ^a   Shen, Zhaoliang ^c   Guo, Yue ^a   Li, Zhuo ^c   Wan, Zhanghui ^a   Liu, Chang ^a   Mei, Xifan ^a  

^a JINZHOU MEDICAL UNIVERSITY   (China)

^b JINING NO 1 PEOPLE S HOSPITAL   (China)

^c Second Hospital of Jinzhou   (China)

Author keywords

autophagy; resveratrol; SIRT1 AMPK signaling pathway; spinal cord injury

Indexed keywords

ADENYLATE KINASE; ADENYLATE KINASE INHIBITOR; BECLIN 1; BRAIN PROTEIN; CASPASE 3; CASPASE 9; ENZYME INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; PROTEIN LC3 B; RESVERATROL; SELISISTAT; SEQUESTOSOME 1; SIRTUIN 1; UNCLASSIFIED DRUG; NEUROPROTECTIVE AGENT; STILBENE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; NEUROPROTECTION; NONHUMAN; PHARMACOLOGICAL BLOCKING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCORING SYSTEM; SIGNAL TRANSDUCTION; SPINAL CORD INJURY; UPREGULATION; WESTERN BLOTTING; ANIMAL; DRUG EFFECTS; METABOLISM; SPINAL CORD; SPINAL CORD INJURIES; SPRAGUE DAWLEY RAT;

ADENYLATE KINASE; ANIMALS; APOPTOSIS; AUTOPHAGY; BECLIN-1; CASPASE 3; CASPASE 9; FEMALE; NEUROPROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SIRTUIN 1; SPINAL CORD; SPINAL CORD INJURIES; STILBENES;

EID: 85014931199     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2017.02.027     Document Type: Article

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