Increased methylation of glucocorticoid receptor gene promoter 1F in peripheral blood of patients with generalized anxiety disorder

Journal of Psychiatric Research

Volumn 91, Issue , 2017, Pages 18-25

  Wang, Wei ^a   Feng, Junqin ^a   Ji, Cui ^a   Mu, Xin ^a,b   Ma, Qingyan ^a   Fan, Yajuan ^a   Chen, Ce ^a   Gao, Chengge ^a   Ma, Xian cang ^a   Zhu, Feng ^a  

^a THE FIRST AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

^b Maternal and Child Health Hospital of Shaanxi Province Northwest Women's and Children's Hospital   (China)

Author keywords

Childhood trauma; DNA methylation; Generalized anxiety disorder; Glucocorticoid receptor; Hypothalamic pituitary adrenal axis

Indexed keywords

CYTOSINE; DEXAMETHASONE; DINUCLEOTIDE; GENOMIC DNA; GLUCOCORTICOID RECEPTOR ALPHA; HYDROCORTISONE; MESSENGER RNA; NR3C1 1 F PROTEIN; PROTEIN; UNCLASSIFIED DRUG; GLUCOCORTICOID RECEPTOR; LYSOZYME; NR3C1 PROTEIN, HUMAN;

ADULT; ARTICLE; BLOOD ANALYSIS; CLINICAL EVALUATION; COMPARATIVE STUDY; CONTROLLED STUDY; DNA METHYLATION; FEMALE; GENE EXPRESSION; GENERALIZED ANXIETY DISORDER; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IC50; MAJOR CLINICAL STUDY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; SENSITIVITY ANALYSIS; ANXIETY DISORDER; BLOOD; CPG ISLAND; GENETICS; METABOLISM; MONONUCLEAR CELL; PATHOLOGY; PATIENT HEALTH QUESTIONNAIRE;

ADULT; ANXIETY DISORDERS; CPG ISLANDS; DNA METHYLATION; FEMALE; HUMANS; HYDROCORTISONE; LEUKOCYTES, MONONUCLEAR; MALE; MURAMIDASE; PATIENT HEALTH QUESTIONNAIRE; PROMOTER REGIONS, GENETIC; RECEPTORS, GLUCOCORTICOID; RNA, MESSENGER;

EID: 85014886223     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2017.01.019     Document Type: Article

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