Functional characterization of a chr13q22.1 pancreatic cancer risk locus reveals long-range interaction and allele-specific effects on DIS3 expression

Human Molecular Genetics

Volumn 25, Issue 21, 2016, Pages 4726-4738

  Hoskins, Jason W ^a   Ibrahim, Abdisamad ^a   Emmanuel, Mickey A ^a   Manmiller, Sarah M ^a   Wu, Yinglun ^a   O'Neill, Maura ^b   Jia, Jinping ^a   Collins, Irene ^a   Zhang, Mingfeng ^a   Thomas, Janelle V ^a   Rost, Lauren M ^a   Das, Sudipto ^b   Parikh, Hemang ^a,c   Haake, Jefferson M ^d   Matters, Gail L ^e   Kurtz, Robert C ^f   Bamlet, William R ^g   Klein, Alison ^h,i   Stolzenberg Solomon, Rachael ^a   Wolpin, Brian M ^j   Yarden, Ronit ^d   Wang, Zhaoming ^a,k   Smith, Jill ^e,l   Olson, Sara H ^f   Andresson, Thorkell ^b   Petersen, Gloria M ^g   Amundadottir, Laufey T ^a   more..

^a NATIONAL CANCER INSTITUTE   (United States)

^b FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^e PENN STATE COLLEGE OF MEDICINE   (United States)

^f MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^g MAYO CLINIC   (United States)

^h JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^j DANA FARBER CANCER INSTITUTE   (United States)

^k ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^l GEORGETOWN UNIVERSITY HOSPITAL   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOID ENHANCER FACTOR 1; MESSENGER RNA; NUCLEAR RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 7 LIKE 1; WNT PROTEIN; DIS3 PROTEIN, HUMAN; EXOSOME MULTIENZYME RIBONUCLEASE COMPLEX;

ALLELE; ARTICLE; BORA GENE; CANCER RISK; CHROMATIN; CHROMOSOME 13Q; CONTROLLED STUDY; DIS3 GENE; ENZYME ACTIVE SITE; FOLLOW UP; GENE; GENE EXPRESSION; GENE FREQUENCY; GENE INTERACTION; GENE LOCUS; GENE MAPPING; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC RISK; GERMLINE MUTATION; HUMAN; HUMAN TISSUE; INDEL MUTATION; KLF12 GENE; KLF5 GENE; NONSENSE MEDIATED MRNA DECAY; PANCREAS CANCER; PIBF1 GENE; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; RNA PROCESSING; SINGLE NUCLEOTIDE POLYMORPHISM; WNT SIGNALING PATHWAY; CHROMOSOMAL MAPPING; CHROMOSOME 13; DNA SEQUENCE; ENZYMOLOGY; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; METABOLISM; PANCREAS TUMOR; PROCEDURES; TUMOR CELL LINE;

ALLELES; CELL LINE, TUMOR; CHROMATIN; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 13; EXOSOME MULTIENZYME RIBONUCLEASE COMPLEX; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INDEL MUTATION; PANCREATIC NEOPLASMS; SEQUENCE ANALYSIS, DNA; TRANSCRIPTION FACTORS;

EID: 85014843250     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddw300     Document Type: Article

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