Merkel cell polyomavirus exhibits dominant control of the tumor genome and transcriptome in virus-associated merkel cell carcinoma

mBio

Volumn 8, Issue 1, 2017, Pages

  Starrett, Gabriel J ^a   Marcelus, Christina ^b   Cantalupo, Paul G ^c   Katz, Joshua P ^c   Cheng, Jingwei ^b,d   Akagi, Keiko ^e,f   Thakuria, Manisha ^d   Rabinowits, Guilherme ^b,d   Wang, Linda C ^d   Symer, David E ^e,f   Pipas, James M ^c   Harris, Reuben S ^a,g   DeCaprio, James A ^d  

^a UNIVERSITY OF MINNESOTA   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e OHIO STATE UNIVERSITY   (United States)

^f OHIO STATE UNIVERSITY   (United States)

^g UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A1; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; GENOMIC DNA; TRANSCRIPTOME;

ADULT; ARTICLE; BINDING AFFINITY; CLINICAL ARTICLE; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA BINDING; EXON; FEMALE; GENE AMPLIFICATION; GENE DELETION; GENE EXPRESSION; GENE LOCUS; GENOME ANALYSIS; GENOMIC INSTABILITY; HUMAN; HUMAN TISSUE; INTRON; MALE; MERKEL CELL POLYOMAVIRUS; MERKEL CELL TUMOR; NONHUMAN; NONSENSE MUTATION; RNA SEQUENCE; SOMATIC MUTATION; STOP CODON; TUMOR SUPPRESSOR GENE; UPREGULATION; VIRUS DNA CELL DNA INTERACTION; VIRUS GENOME; VIRUS IDENTIFICATION; VIRUS REPLICATION; AGED; CARCINOGENESIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HOST PATHOGEN INTERACTION; MERKEL CELL CARCINOMA; MIDDLE AGED; PATHOGENICITY; PATHOLOGY; VERY ELDERLY; VIROLOGY;

AGED; AGED, 80 AND OVER; CARCINOGENESIS; CARCINOMA, MERKEL CELL; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; HUMANS; MALE; MERKEL CELL POLYOMAVIRUS; MIDDLE AGED; VIRUS INTEGRATION;

EID: 85014766364     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.02079-16     Document Type: Article

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