Universal versus targeted additional contact precautions for multidrug-resistant organism carriage for patients admitted to an intensive care unit

American Journal of Infection Control

Volumn 45, Issue 7, 2017, Pages 728-734

  Djibré, Michel ^a   Fedun, Samuel ^a   Le Guen, Pierre ^a   Vimont, Sophie ^a,b   Hafiani, Mehdi ^a,b   Fulgencio, Jean Pierre ^a   Parrot, Antoine ^a   Denis, Michel ^a   Fartoukh, Muriel ^a,b  

^a ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^b SORBONNE UNIVERSITÉ   (France)

Author keywords

Acquisition; Infection; Isolation; Screening

Indexed keywords

ADDITIONAL CONTACT PRECAUTION; ADULT; AGED; ARTICLE; CARBAPENEM RESISTANT ENTEROBACTERIACEAE; CONTACT ISOLATION; CONTACT PRECAUTION; CRITICALLY ILL PATIENT; FEMALE; HOSPITAL ADMISSION; HOSPITAL INFECTION; HUMAN; INFECTION CONTROL; INFECTION RATE; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MULTIDRUG RESISTANCE; MULTIDRUG RESISTANT ORGANISM; NONHUMAN; OBSERVATIONAL STUDY; ORGANISMS; POSTOPERATIVE CARE; RESPIRATORY FAILURE; RISK FACTOR; SCREENING; SEPSIS; SEPTIC SHOCK; SURGICAL INTENSIVE CARE UNIT; UNIVERSAL PRECAUTION; BACTERIAL INFECTION; DISEASE TRANSMISSION; FRANCE; HETEROZYGOTE; INTENSIVE CARE UNIT; MICROBIOLOGY; MIDDLE AGED; PREVENTION AND CONTROL; PROCEDURES; TRANSMISSION;

ADULT; AGED; BACTERIAL INFECTIONS; CARRIER STATE; DISEASE TRANSMISSION, INFECTIOUS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FEMALE; FRANCE; HUMANS; INFECTION CONTROL; INTENSIVE CARE UNITS; MALE; MIDDLE AGED;

EID: 85014765772     PISSN: 01966553     EISSN: 15273296     Source Type: Journal    
DOI: 10.1016/j.ajic.2017.02.001     Document Type: Article

References (41)

1. Drieux, L., Brossier, F., Duquesnoy, O., Aubry, A., Robert, J., Sougakoff, W., et al. Increase in hospital-acquired bloodstream infections caused by extended spectrum beta-lactamase-producing Escherichia coli in a large French teaching hospital. Eur J Clin Microbiol Infect Dis 28 (2009), 491–498, 10.1007/s10096-008-0656-6.
2. Meyer, E., Schwab, F., Schroeren-Boersch, B., Gastmeier, P., Dramatic increase of third-generation cephalosporin-resistant E. coli in German intensive care units: secular trends in antibiotic drug use and bacterial resistance, 2001 to 2008. Crit Care, 14, 2010, R113, 10.1186/cc9062.
3. Bonten, M.J., Weinstein, R.A., The role of colonization in the pathogenesis of nosocomial infections. Infect Control Hosp Epidemiol 17 (1996), 193–200.
4. Vasudevan, A., Mukhopadhyay, A., Li, J., Yuen, E.G.Y., Tambyah, P.A., A prediction tool for nosocomial multi-drug resistant gram-negative bacilli infections in critically ill patients—prospective observational study. BMC Infect Dis, 14, 2014, 615, 10.1186/s12879-014-0615-z.
5. Blot, S., Depuydt, P., Vogelaers, D., Decruyenaere, J., De Waele, J., Hoste, E., et al. Colonization status and appropriate antibiotic therapy for nosocomial bacteremia caused by antibiotic-resistant gram-negative bacteria in an intensive care unit. Infect Control Hosp Epidemiol 26 (2005), 575–579, 10.1086/502575.
6. Tabah, A., Koulenti, D., Laupland, K., Misset, B., Valles, J., Bruzzi de Carvalho, F., et al. Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study. Intensive Care Med 38 (2012), 1930–1945, 10.1007/s00134-012-2695-9.
7. Lee, S.Y., Kotapati, S., Kuti, J.L., Nightingale, C.H., Nicolau, D.P., Impact of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species on clinical outcomes and hospital costs: a matched cohort study. Infect Control Hosp Epidemiol 27 (2006), 1226–1232, 10.1086/507962.
8. de Kraker, M.E.A., Wolkewitz, M., Davey, P.G., Koller, W., Berger, J., Nagler, J., et al. Burden of antimicrobial resistance in European hospitals: excess mortality and length of hospital stay associated with bloodstream infections due to Escherichia coli resistant to third-generation cephalosporins. J Antimicrob Chemother 66 (2011), 398–407, 10.1093/jac/dkq412.
9. Siegel, J.D., Rhinehart, E., Jackson, M., Chiarello, L., Health Care Infection Control Practices Advisory Committee. 2007 guideline for isolation precautions: preventing transmission of infectious agents in health care settings. Am J Infect Control 35:10 Suppl 2 (2007), S65–164, 10.1016/j.ajic.2007.10.007.
10. Landelle, C., Pagani, L., Harbarth, S., Is patient isolation the single most important measure to prevent the spread of multidrug-resistant pathogens?. Virulence 4 (2013), 163–171, 10.4161/viru.22641.
11. Bearman, G., Stevens, M.P., Control of drug-resistant pathogens in endemic settings: contact precautions, controversies, and a proposal for a less restrictive alternative. Curr Infect Dis Rep 14 (2012), 620–626, 10.1007/s11908-012-0299-8.
12. Pogorzelska, M., Stone, P.W., Larson, E.L., Wide variation in adoption of screening and infection control interventions for multidrug-resistant organisms: a national study. Am J Infect Control 40 (2012), 696–700, 10.1016/j.ajic.2012.03.014.
13. Harbarth, S., Masuet-Aumatell, C., Schrenzel, J., Francois, P., Akakpo, C., Renzi, G., et al. Evaluation of rapid screening and pre-emptive contact isolation for detecting and controlling methicillin-resistant Staphylococcus aureus in critical care: an interventional cohort study. Crit Care, 10, 2006, R25, 10.1186/cc3982.
14. Jain, R., Kralovic, S.M., Evans, M.E., Ambrose, M., Simbartl, L.A., Obrosky, D.S., et al. Veterans Affairs initiative to prevent methicillin-resistant Staphylococcus aureus infections. N Engl J Med 364 (2011), 1419–1430, 10.1056/NEJMoa1007474.
15. Robicsek, A., Beaumont, J.L., Paule, S.M., Hacek, D.M., Thomson, R.B. Jr, Kaul, K.L., et al. Universal surveillance for methicillin-resistant Staphylococcus aureus in 3 affiliated hospitals. Ann Intern Med 148 (2008), 409–418.
16. Lucet, J.-C., Paoletti, X., Lolom, I., Paugam-Burtz, C., Trouillet, J.L., Timsit, J.F., et al. Successful long-term program for controlling methicillin-resistant Staphylococcus aureus in intensive care units. Intensive Care Med 31 (2005), 1051–1057, 10.1007/s00134-005-2679-0.
17. Harris, A.D., Pineles, L., Belton, B., Johnson, J.K., Shardell, M., Loeb, M., et al. Universal glove and gown use and acquisition of antibiotic-resistant bacteria in the ICU: a randomized trial. JAMA 310 (2013), 1571–1580, 10.1001/jama.2013.277815.
18. Huskins, W.C., Huckabee, C.M., O'Grady, N.P., Murray, P., Kopetskie, H., Zimmer, L., et al. Intervention to reduce transmission of resistant bacteria in intensive care. N Engl J Med 364 (2011), 1407–1418, 10.1056/NEJMoa1000373.
19. Borg, M.A., Hulscher, M., Scicluna, E.A., Richards, J., Azanowsky, J.M., Xuereb, D., et al. Prevention of meticillin-resistant Staphylococcus aureus bloodstream infections in European hospitals: moving beyond policies. J Hosp Infect 87 (2014), 203–211, 10.1016/j.jhin.2014.05.003.
20. Martínez-Reséndez, M.F., Garza-González, E., Mendoza-Olazaran, S., Herrera-Guerra, A., Rodríguez-López, J.M., Pérez-Rodriguez, E., et al. Impact of daily chlorhexidine baths and hand hygiene compliance on nosocomial infection rates in critically ill patients. Am J Infect Control 42 (2014), 713–717, 10.1016/j.ajic.2014.03.354.
21. Hess, A.S., Shardell, M., Johnson, J.K., Thom, K.A., Roghmann, M.C., Netzer, G., et al. A randomized controlled trial of enhanced cleaning to reduce contamination of healthcare worker gowns and gloves with multidrug-resistant bacteria. Infect Control Hosp Epidemiol 34 (2013), 487–493, 10.1086/670205.
22. Nseir, S., Blazejewski, C., Lubret, R., Wallet, F., Courcol, R., Durocher, A., Risk of acquiring multidrug-resistant Gram-negative bacilli from prior room occupants in the intensive care unit. Clin Microbiol Infect 17 (2011), 1201–1208, 10.1111/j.1469-0691.2010.03420.x.
23. Morgan, D.J., Pineles, L., Shardell, M., Graham, M.M., Mohammadi, S., Forrest, G.N., et al. The effect of contact precautions on healthcare worker activity in acute care hospitals. Infect Control Hosp Epidemiol 34 (2013), 69–73, 10.1086/668775.
24. Morgan, D.J., Diekema, D.J., Sepkowitz, K., Perencevich, E.N., Adverse outcomes associated with contact precautions: a review of the literature. Am J Infect Control 37 (2009), 85–93, 10.1016/j.ajic.2008.04.257.
25. Smith, R., Coast, J., The true cost of antimicrobial resistance. BMJ, 346, 2013, f1493.
26. Razazi, K., Derde, L.P.G., Verachten, M., Legrand, P., Lesprit, P., Brun-Buisson, C., Clinical impact and risk factors for colonization with extended-spectrum β-lactamase-producing bacteria in the intensive care unit. Intensive Care Med 38 (2012), 1769–1778, 10.1007/s00134-012-2675-0.
27. American Thoracic Society, Infectious Diseases Society of America, Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 171 (2005), 388–416, 10.1164/rccm.200405-644ST.
28. Cardoso, T., Ribeiro, O., Aragão, I.C., Costa-Pereira, A., Sarmento, A.E., Additional risk factors for infection by multidrug-resistant pathogens in healthcare-associated infection: a large cohort study. BMC Infect Dis, 12, 2012, 375, 10.1186/1471-2334-12-375.
29. Diekema, D.J., Pfaller, M.A., Rapid detection of antibiotic-resistant organism carriage for infection prevention. Clin Infect Dis 56 (2013), 1614–1620, 10.1093/cid/cit038.
30. Roisin, S., Laurent, C., Denis, O., Dramaix, M., Nonhoff, C., Hallin, M., et al. Impact of rapid molecular screening at hospital admission on nosocomial transmission of methicillin-resistant Staphylococcus aureus: cluster randomised trial. PLoS ONE, 9, 2014, 10.1371/journal.pone.0096310 e96310.
31. Dananché C., Bénet, T., Allaouchiche, B., Hernu, R., Argaud, L., Dauwalder, O., et al. Targeted screening for third-generation cephalosporin-resistant Enterobacteriaceae carriage among patients admitted to intensive care units: a quasi-experimental study. Crit Care, 19, 2015, 38, 10.1186/s13054-015-0754-7.
32. Zahar, J.-R., Poirel, L., Dupont, C., Fortineau, N., Nassif, X., Nordmann, P., About the usefulness of contact precautions for carriers of extended-spectrum beta-lactamase-producing Escherichia coli. BMC Infect Dis, 15, 2015, 512, 10.1186/s12879-015-1244-x.
33. Ledoux, G., Six, S., Lawson, R., Labreuche, J., Blazejewski, C., Wallet, F., et al. Impact of a targeted isolation strategy at intensive-care-unit-admission on intensive-care-unit-acquired infection related to multidrug-resistant bacteria: a prospective uncontrolled before-after study. Clin Microbiol Infect, 22, 2016, 10.1016/j.cmi.2016.07.012 888.e11-8.
34. Schoevaerdts, D., Bogaerts, P., Grimmelprez, A., de Saint-Hubert, M., Delaere, B., Jamart, J., et al. Clinical profiles of patients colonized or infected with extended-spectrum beta-lactamase producing Enterobacteriaceae isolates: a 20 month retrospective study at a Belgian University Hospital. BMC Infect Dis, 11, 2011, 12, 10.1186/1471-2334-11-12.
35. Aliberti, S., Di Pasquale, M., Zanaboni, A.M., Cosentini, R., Brambilla, A.M., Seghezzi, S., et al. Stratifying risk factors for multidrug-resistant pathogens in hospitalized patients coming from the community with pneumonia. Clin Infect Dis 54 (2012), 470–478, 10.1093/cid/cir840.
36. Tumbarello, M., Trecarichi, E.M., Bassetti, M., De Rosa, F.G., Spanu, T., Di Meco, E., et al. Identifying patients harboring extended-spectrum-beta-lactamase-producing Enterobacteriaceae on hospital admission: derivation and validation of a scoring system. Antimicrob Agents Chemother 55 (2011), 3485–3490, 10.1128/AAC.00009-11.
37. Johnson, S.W., Anderson, D.J., May, D.B., Drew, R.H., Utility of a clinical risk factor scoring model in predicting infection with extended-spectrum β-lactamase-producing Enterobacteriaceae on hospital admission. Infect Control Hosp Epidemiol 34 (2013), 385–392, 10.1086/669858.
38. Biehl, L.M., Schmidt-Hieber, M., Liss, B., Cornely, O.A., Vehreschild, M.J.G.T., Colonization and infection with extended spectrum beta-lactamase producing Enterobacteriaceae in high-risk patients—review of the literature from a clinical perspective. Crit Rev Microbiol 42 (2016), 1–16, 10.3109/1040841X.2013.875515.
39. Grohs, P., Podglajen, I., Guerot, E., Bellenfant, F., Caumont-Prim, A., Kac, G., et al. Assessment of five screening strategies for optimal detection of carriers of third-generation cephalosporin-resistant Enterobacteriaceae in intensive care units using daily sampling. Clin Microbiol Infect 20 (2014), O879–86, 10.1111/1469-0691.12663.
40. Harris, A.D., Nemoy, L., Johnson, J.A., Martin-Carnahan, A., Smith, D.L., Standiford, H., et al. Co-carriage rates of vancomycin-resistant Enterococcus and extended-spectrum beta-lactamase-producing bacteria among a cohort of intensive care unit patients: implications for an active surveillance program. Infect Control Hosp Epidemiol 25 (2004), 105–108, 10.1086/502358.
41. Azim, A., Dwivedi, M., Rao, P.B., Baronia, A.K., Singh, R.K., Prasad, K.N., et al. Epidemiology of bacterial colonization at intensive care unit admission with emphasis on extended-spectrum beta-lactamase- and metallo-beta-lactamase-producing Gram-negative bacteria–an Indian experience. J Med Microbiol 59:Pt 8 (2010), 955–960, 10.1099/jmm.0.018085-0.