Epidemiology of bacterial colonization at intensive care unit admission with emphasis on extended-spectrum β-lactamase- and metallo-β- lactamase-producing Gram-negative bacteria - An Indian experience

Journal of Medical Microbiology

Volumn 59, Issue 8, 2010, Pages 955-960

  Azim, Afzal ^a   Dwivedi, Mayank ^a   Rao, P Bhaskar ^a   Baronia, A K ^a   Singh, R K ^a   Prasad, K N ^a   Poddar, Banani ^a   Mishra, Anshuman ^a   Gurjar, Mohan ^a   Dhole, T N ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE; EXTENDED SPECTRUM BETA LACTAMASE; METALLO BETA LACTAMASE; BACTERIAL PROTEIN;

ACINETOBACTER; ACINETOBACTER BAUMANNII; ADULT; AGED; ANTIBIOTIC THERAPY; ARTICLE; ARTIFICIAL VENTILATION; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIUM IDENTIFICATION; COMORBIDITY; ENTEROBACTERIACEAE; FEMALE; GRAM NEGATIVE BACTERIUM; GRAM NEGATIVE INFECTION; HOSPITAL INFECTION; HOSPITALIZATION; HUMAN; INDIA; INFECTION RISK; INFECTION SENSITIVITY; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; BIOSYNTHESIS; CROSS INFECTION; ENZYMOLOGY; HETEROZYGOTE; ISOLATION AND PURIFICATION; MICROBIOLOGY; MIDDLE AGED; MOUTH; NOSE CAVITY; PREVALENCE; RECTUM;

ADULT; AGED; BACTERIAL PROTEINS; BETA-LACTAMASES; CARRIER STATE; CROSS INFECTION; FEMALE; GRAM-NEGATIVE BACTERIA; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; INDIA; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; MOUTH; NASAL CAVITY; PREVALENCE; RECTUM; YOUNG ADULT;

EID: 77955289819     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.018085-0     Document Type: Article

References (24)

1. Bonten, M. J. & Weinstein, R. A. (1996). The role of colonization in the pathogenesis of nosocomial infections. Infect Control Hosp Epidemiol 17, 193-200. (Pubitemid 126469337)
2. Bonten, M. J., Hayden, M. K., Nathan, C., van Voorhis, J., Matushek, M., Slaughter, S., Rice, T. & Weinstein, R. A. (1996). Epidemiology of colonisation of patients and environment with vancomycin-resistant enterococci. Lancet 348, 1615-1619. (Pubitemid 27007060)
3. Brawley, R. L., Weber, D. J., Samsa, G. P. & Rutala, W. A. (1989). Multiple nosocomial infections. An incidence study. Am J Epidemiol 130, 769-780. (Pubitemid 19240205)
4. Brenwald, N. P., Jevons, G., Andrews, J. M., Xiong, J. H., Hawkey, P. M. & Wise, R. (2003). An outbreak of a CTX-M-type β-lactamase-producing Klebsiella pneumoniae: the importance of using cefpodoxime to detect extended-spectrum b-lactamases. J Antimicrob Chemother 51, 195-196. (Pubitemid 36163857)
5. Bryan-Brown, C. W. (1992). Pathway to the present: a personal view of critical care. In Critical Care, 2nd edn, pp. 5-6. Edited by J. M. Civetta, R. W. Taylor & R. R. Kirby. Philadelphia, PA: J. B. Lippincott.
6. CLSI (2006). Performance Standards for Antimicrobial Disk Susceptibility Tests, approved standard, 9th edn, M2-A9. Wayne, PA: Clinical and Laboratory Standards Institute.
7. Drakulovic, M. B., Bauer, T. T., Torres, A., Gonzalez, J., Rodriguez, M.-J. & Angrill, J. (2001). Initial bacterial colonization in patients admitted to a respiratory intensive care unit: bacteriological pattern and risk factors. Respiration 68, 58-66. (Pubitemid 32172956)
8. Edelstein, M., Pimkin, M., Palagin, I., Edelstein, I. & Stratchounski, L. (2003). Prevalence and molecular epidemiology of CTX-M extendedspectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Russian hospitals. Antimicrob Agents Chemother 47, 3724-3732. (Pubitemid 37484979)
9. Ellington, M. J., Kistler, J., Livermore, D. M. & Woodford, N. (2007). Multiplex PCR for rapid detection of genes encoding acquired metallo-β-lactamases. J Antimicrob Chemother 59, 321-322. (Pubitemid 47072076)
10. Ensor, V. M., Shahid, M., Evans, J. T. & Hawkey, P. M. (2006). Occurrence, prevalence and genetic environment of CTX-M β-lactamases in Enterobacteriaceae from Indian hospitals. J Antimicrob Chemother 58, 1260-1263.
11. Franklin, C., Liolios, L. & Peleg, A. Y. (2006). Phenotypic detection of carbapenem-susceptible metallo-β-lactamase-producing gram-negative bacilli in the clinical laboratory. J Clin Microbiol 44, 3139-3144. (Pubitemid 44413743)
12. Garner, J. S., Jarvis, W. R., Emori, T. G., Horan, T. C. & Hughes, J. M. (1988). CDC definitions for nosocomial infections. Am J Infect Control 16, 128-140.
13. Harris, A. D., McGregor, J. C., Johnson, J. A., Strauss, S. M., Moore, A. C., Standiford, H. C., Hebden, J. N. & Morris, J. G., Jr (2007). Risk factors for colonization with extended-spectrum β-lactamase-producing bacteria and intensive care unit admission. Emerg Infect Dis 13, 1144-1149. (Pubitemid 47359156)
14. Heyland, D. K., Cook, D. J., Griffith, L., Keenan, S. P. & Brun Buisson, C. for the Canadian Critical Care Trials Group (1999). The attributable morbidity and mortality of ventilator-associated pneumonia in the critically ill patient. Am J Respir Crit Care Med 159, 1249-1256.
15. Inan, D., Saba, R., Gunseren, F., Ongut, G., Turhan, O., Yalcin, A. N. & Mamikoglu, L. (2005). Daily antibiotic cost of nosocomial infections in a Turkish university hospital. BMC Infect Dis 5, 5. (Pubitemid 41363820)
16. Jarlier, V., Nicolas, M., Fournier, G. & Philippon, A. (1988). Extended broad-spectrum β-lactamases conferring transferable resistance to newer β-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility pattern. Rev Infect Dis 10, 867-878.
17. Jarvis, W. R. (1996). Selected aspects of socioeconomic impact of nosocomial infections: morbidity, mortality, cost, and prevention. Infect Control Hosp Epidemiol 17, 552-557.
18. Lee, S. H., Kim, J. Y., Lee, S. K., Jin, W., Kang, S. G. & Lee, K. J. (2000). Discriminatory detection of extended-spectrum β-lactamases by restriction fragment length dimorphism-polymerase chain reaction. Lett Appl Microbiol 31, 307-312.
19. Lee, K., Chong, Y., Shin, H. B., Kim, Y. A., Yong, D. & Yum, J. H. (2001). Modified Hodge and EDTA-disk synergy tests to screen metallo-β-lactamase-producing strains of Pseudomonas and Acinetobacter species. Clin Microbiol Infect 7, 88-91. (Pubitemid 34960278)
20. Luzzaro, F., Mezzatesta, M., Mugnaioli, C., Perilli, M., Stefani, S., Amicosante, G., Rossolini, G. M. & Toniolo, A. (2006). Trends in production of extended-spectrum β-lactamases among enterobacteria of medical interest: report of the second Italian nationwide survey. J Clin Microbiol 44, 1659-1664. (Pubitemid 43726252)
21. Muzaheed, Doi, Y., Adams-Haduch, J. M., Endimiani, A., Sidjabat, H. E., Gaddad, S. M. & Paterson, D. L. (2008). High prevalence of CTX-M-15-producing Klebsiella pneumoniae among inpatients and outpatients with urinary tract infection in Southern India. J Antimicrob Chemother 61, 1393-1394. (Pubitemid 351753615)
22. NCCLS (2000). Performance Standards for Antimicrobial Disk Susceptibility Test, approved standard, 7th edn, vol. 20 no. 1, M2-A7. Wayne, PA: National Committee for Clinical Laboratory Standards.
23. Pournaras, S., Ikonomidis, A., Kristo, I., Tsakris, A. & Maniatis, A. N. (2004). CTX-M enzymes are the most common extended-spectrum β-lactamases among Escherichia coli in a tertiary Greek hospital. J Antimicrob Chemother 54, 574-575. (Pubitemid 39177493)
24. Sambrook, J., Fritsch, E. F. & Miniatis, T. (1989). Extraction and purification of plasmid DNA. In Molecular Cloning: a Laboratory Manual, 2nd edn, pp. 1.32-1.34. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.