Veterans Affairs Initiative to Prevent Methicillin-Resistant Staphylococcus aureus Infections

New England Journal of Medicine

Volumn 364, Issue 15, 2011, Pages 1419-1430

  Jain, Rajiv ^a   Kralovic, Stephen M ^a   Evans, Martin E ^a   Ambrose, Meredith ^a   Simbartl, Loretta A ^a   Obrosky, D Scott ^a   Render, Marta L ^a   Freyberg, Ron W ^a   Jernigan, John A ^a   Muder, Robert R ^a   Miller, LaToya J ^a   Roselle, Gary A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL TRANSMISSION; BACTERIUM CULTURE; CONTROLLED STUDY; DATA BASE; HAND WASHING; HEALTH CARE SYSTEM; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HOSPITAL HYGIENE; HOSPITAL INFECTION; HUMAN; INFECTION CONTROL; INFECTION RATE; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; NOSE SMEAR; PATIENT TRANSPORT; PRIORITY JOURNAL; PUBLIC HOSPITAL; TREND STUDY;

EID: 79954553689     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1007474     Document Type: Article

References (35)

1. Klein E, Smith DL, Laxminarayan R. Hospitalizations and deaths caused by methicillin-resistant Staphylococcus aureus, United States, 1999-2005. Emerg Infect Dis 2007;13:1840-6. (Pubitemid 350248484)
2. Hidron AI, Edwards JR, Patel J, et al. NHSN annual update: antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006- 2007. Infect Control Hosp Epidemiol 2008; 29:996-1011. [Erratum, Infect Control Hosp Epidemiol 2009;30:107.]
3. Muto CA, Jernigan JA, Ostrowsky BE, et al. SHEA guideline for preventing nosocomial transmission of multidrug-resistant strains of Staphylococcus aureus and enterococcus. Infect Control Hosp Epidemiol 2003;24:362-86. (Pubitemid 36612323)
4. Muder RR, Cunningham C, McCray E, et al. Implementation of an industrial systems-engineering approach to reduce the incidence of methicillin-resistant Staphylococcus aureus infection. Infect Control Hosp Epidemiol 2008;29:702-8.
5. Positive Deviance Initiative home page. (http://www.positivedeviance.org. )
6. Informed consent for clinical treatments and procedures. VHA handbook 1004.01. Washington, DC: Veterans Health Administration Office of Ethics, 2009. (http://www.ethics.va.gov/docs/policy/VHA-Handbook-1004-01-Informed-Consent- Policy-20090814.pdf.)
7. Siegel JD, Rhinehart E, Jackson M, Chiarello L. 2007 Guideline for isolation precautions: preventing transmission of infectious agents in health care settings. Am J Infect Control 2007;35:Suppl 2:S65-S164. (Pubitemid 350213178)
8. Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008;36:309-32. [Erratum, Am J Infect Control 2008;36:655.] (Pubitemid 351763841)
9. Centers for Disease Control and Prevention. Identifying healthcare-associated infections (HAI) in NHSN. (http://www.cdc.gov/nhsn/PDFs/ pscManual/2PSC-IdentifyingHAIs-NHSNcurrent.pdf.)
10. Burton DC, Edwards JR, Horan TC, Jernigan JA, Fridkin SK. Methicillin-resistant Staphylococcus aureus central line-associated bloodstream infections in US intensive care units, 1997-2007. JAMA 2009; 301:727-36.
11. Kallen AJ, Mu Y, Bulens S, et al. Health care-associated invasive MRSA infections, 2005-2008. JAMA 2010;304:641-8.
12. Harbarth S, Martin Y, Rohner P, Henry N, Auckenthaler R, Pittet D. Effect of delayed infection control measures on a hospital outbreak of methicillin-resistant Staphylococcus aureus. J Hosp Infect 2000; 46:43-9.
13. Lucet JC, Paoletti X, Lolom I, et al. Successful long-term program for controlling methicillin-resistant Staphylococcus aureus in intensive care units. Intensive Care Med 2005;31:1051-7. (Pubitemid 41125335)
14. Huang SS, Yokoe DS, Hinrichsen VL, et al. Impact of routine intensive care unit surveillance cultures and resultant barrier precautions on hospital-wide methicillinresistant Staphylococcus aureus bacteremia. Clin Infect Dis 2006;43:971-8. (Pubitemid 44631095)
15. Boyce JM, Havill NL, Kohan C, Dumigan DG, Ligi CE. Do infection control measures work for methicillin-resistant Staphylococcus aureus? Infect Control Hosp Epidemiol 2004;25:395-401. (Pubitemid 38621086)
16. Robicsek A, Beaumont JL, Paule SM, et al. Universal surveillance for methicillin- resistant Staphylococcus aureus in 3 affiliated hospitals. Ann Intern Med 2008;148: 409-18. (Pubitemid 351665440)
17. Clancy M, Graepler A, Wilson M, Douglas I, Johnson J, Price CS. Active screening in high-risk units is an effective and cost-avoidant method to reduce the rate of methicillin-resistant Staphylococcus aureus infection in the hospital. Infect Control Hosp Epidemiol 2006;27:1009-17. (Pubitemid 44670975)
18. Chowers MY, Paitan Y, Gottesman BS, Gerber B, Ben-Nissan Y, Shitrit P. Hospitalwide methicillin-resistant Staphylococcus aureus control program: a 5-year followup. Infect Control Hosp Epidemiol 2009; 30:778-81.
19. Pan A, Carnevale G, Catenazzi P, et al. Trends in methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections: effect of the MRSA "search and isolate" strategy in a hospital in Italy with hyperendemic MRSA. Infect Control Hosp Epidemiol 2005;26:127-33. (Pubitemid 40445015)
20. Vos MC, Behrendt MD, Melles DC, et al. 5 Years of experience implementing a methicillin-resistant Staphylococcus aureus search and destroy policy at the largest university medical center in the Netherlands. Infect Control Hosp Epidemiol 2009;30:977-84.
21. Gorwitz RJ, Kruszon-Moran D, McAllister SK, et al. Changes in the prevalence of nasal colonization with Staphylococcus aureus in the United States, 2001-2004. J Infect Dis 2008;197:1226-34. (Pubitemid 351632753)
22. Merrer J, Santoli F, Appéré de Vecchi C, Tran B, De Jonghe B, Outin H. "Colonization pressure" and risk of acquisition of methicillin-resistant Staphylococcus aureus in a medical intensive care unit. Infect Control Hosp Epidemiol 2000;21:718-23.
23. Williams VR, Callery S, Vearncombe M, Simor AE. The role of colonization pressure in nosocomial transmission of methicillin-resistant Staphylococcus aureus. Am J Infect Control 2009;37:106-10.
24. Wolk DM, Picton E, Johnson D, et al. Multicenter evaluation of the Cepheid Xpert methicillin-resistant Staphylococcus aureus (MRSA) test as a rapid screening method for detection of MRSA in nares. J Clin Microbiol 2009;47:758-64.
25. Chang S, Sethi AK, Eckstein BC, Stiefel U, Cadnum JL, Donskey CJ. Skin and environmental contamination with methicillin- resistant Staphylococcus aureus among carriers identified clinically versus through active surveillance. Clin Infect Dis 2009; 48:1423-8.
26. Croft CA, Mejia VA, Barker DE, et al. Methicillin-resistant Staphylococcus aureus in a trauma population: does colonization predict infection? Am Surg 2009;75:458-61.
27. Huang SS, Platt R. Risk of methicillinresistant Staphylococcus aureus infection after previous infection or colonization. Clin Infect Dis 2003;36:281-5. (Pubitemid 36169662)
28. Pujol M, Peña C, Pallares R, et al. Nosocomial Staphylococcus aureus bacteremia among nasal carriers of methicillinresistant and methicillin-susceptible strains. Am J Med 1996;100:509-16. (Pubitemid 26170474)
29. Davis KA, Stewart JJ, Crouch HK, Florez CE, Hospenthal DR. Methicillin-resistant Staphylococcus aureus (MRSA) nares colonization at hospital admission and its effect on subsequent MRSA infection. Clin Infect Dis 2004;39:776-82. (Pubitemid 39244289)
30. Robicsek A, Beaumont JL, Thomson RB Jr, Govindarajan G, Peterson LR. Topical therapy for methicillin-resistant Staphylococcus aureus colonization: impact on infection risk. Infect Control Hosp Epidemiol 2009;30:623-32.
31. WHO guidelines on hand hygiene in health care. Geneva: World Health Organization, 2009. (http://whqlibdoc.who.int/publications/2009/9789241597906- eng.pdf.)
32. Boyce JM, Potter-Bynoe G, Chenevert C, King T. Environmental contamination due to methicillin-resistant Staphylococcus aureus: possible infection control implications. Infect Control Hosp Epidemiol 1997; 18:622-7. (Pubitemid 127470494)
33. Lucet JC, Chevret S, Durand-Zaleski I, Chastang C, Régnier B. Prevalence and risk factors for carriage of methicillinresistant Staphylococcus aureus at admission to the intensive care unit: results of a multicenter study. Arch Intern Med 2003;163: 181-8. (Pubitemid 36124003)
34. Lee BY, Bailey RR, Smith KJ, et al. Universal methicillin-resistant Staphylococcus aureus (MRSA) surveillance for adults at hospital admission: an economic model and analysis. Infect Control Hosp Epidemiol 2010;31:598-606.
35. Nyman JA, Lees CH, Bockstedt LA, et al. Cost of screening intensive care unit patients for methicillin-resistant Staphylococcus aureus in hospitals. Am J Infect Control 2011;39:27-34.