-
1
-
-
77955647582
-
Gut Microbiota in Health and Disease
-
Sekirov, I., Russell, S. L., Antunes, L. C. M., Finlay, B. B. Gut Microbiota in Health and Disease. Physiol. Rev. 90, 859-904 (2010).
-
(2010)
Physiol. Rev.
, vol.90
, pp. 859-904
-
-
Sekirov, I.1
Russell, S.L.2
Antunes, L.C.M.3
Finlay, B.B.4
-
2
-
-
77957236209
-
The immune system and the gut microbiota: Friends or foes
-
Cerf-Bensussan, N., Gaboriau-Routhiau, V. The immune system and the gut microbiota: friends or foes Nat. Rev. Immunol. 10, 735-44 (2010).
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 735-744
-
-
Cerf-Bensussan, N.1
Gaboriau-Routhiau, V.2
-
3
-
-
0021301954
-
Microbial Digestion of Complex Carbohydrates in Man
-
Cummings, J. H. Microbial Digestion of Complex Carbohydrates in Man. Proc. Nutr. Soc. 43, 35-44 (1984).
-
(1984)
Proc. Nutr. Soc.
, vol.43
, pp. 35-44
-
-
Cummings, J.H.1
-
4
-
-
0018908502
-
Vitamin B12 synthesis by human small intestinal bacteria
-
Albert, M. J., Mathan, V. I., Baker, S. J. Vitamin B12 synthesis by human small intestinal bacteria. Nature 283, 781-782 (1980).
-
(1980)
Nature
, vol.283
, pp. 781-782
-
-
Albert, M.J.1
Mathan, V.I.2
Baker, S.J.3
-
5
-
-
8144226856
-
The gut microbiota as an environmental factor that regulates fat storage
-
Bäckhed, F., et al. The gut microbiota as an environmental factor that regulates fat storage. Proc. Natl. Acad. Sci. USA 101, 15718-23 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15718-15723
-
-
Bäckhed, F.1
-
6
-
-
0036399823
-
How host-microbial interactions shape the nutrient environment of the mammalian intestine
-
Hooper, L. V., Midtvedt, T., Gordon, J. I. How host-microbial interactions shape the nutrient environment of the mammalian intestine. Annu. Rev. Nutr. 22, 283-307 (2002).
-
(2002)
Annu. Rev. Nutr.
, vol.22
, pp. 283-307
-
-
Hooper, L.V.1
Midtvedt, T.2
Gordon, J.I.3
-
7
-
-
83655191579
-
Microbes and microbial effector molecules in treatment of inflammatory disorders
-
Kelly, D., Delday, M. I., Mulder, I. Microbes and microbial effector molecules in treatment of inflammatory disorders. Immunol. Rev. 245, 27-44 (2012).
-
(2012)
Immunol. Rev.
, vol.245
, pp. 27-44
-
-
Kelly, D.1
Delday, M.I.2
Mulder, I.3
-
8
-
-
84883110880
-
Richness of human gut microbiome correlates with metabolic markers
-
Le Chatelier, E., et al. Richness of human gut microbiome correlates with metabolic markers. Nature 500, 541-6 (2013).
-
(2013)
Nature
, vol.500
, pp. 541-546
-
-
Le Chatelier, E.1
-
9
-
-
47249096253
-
Role of gut microflora in the development of obesity and insulin resistance following high-fat diet feeding
-
Paris
-
Cani, P. D., Delzenne, N. M., Amar, J., Burcelin, R. Role of gut microflora in the development of obesity and insulin resistance following high-fat diet feeding. Pathol. Biol. (Paris). 56, 305-9 (2008).
-
(2008)
Pathol. Biol.
, vol.56
, pp. 305-309
-
-
Cani, P.D.1
Delzenne, N.M.2
Amar, J.3
Burcelin, R.4
-
10
-
-
84879369738
-
Commensal bacteria at the interface of host metabolism and the immune system
-
Brestoff, J. R., Artis, D. Commensal bacteria at the interface of host metabolism and the immune system. Nat. Immunol. 14, 676-84 (2013).
-
(2013)
Nat. Immunol.
, vol.14
, pp. 676-684
-
-
Brestoff, J.R.1
Artis, D.2
-
11
-
-
84870284140
-
MR1 presents microbial Vitamin B metabolites to MAIT cells
-
Kjer-Nielsen, L., et al. MR1 presents microbial vitamin B metabolites to MAIT cells. Nature 491, 717-23 (2012).
-
(2012)
Nature
, vol.491
, pp. 717-723
-
-
Kjer-Nielsen, L.1
-
12
-
-
84873342775
-
Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist
-
Sayin, S. I., et al. Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist. Cell Metab. 17, 225-35 (2013).
-
(2013)
Cell Metab.
, vol.17
, pp. 225-235
-
-
Sayin, S.I.1
-
13
-
-
0026517010
-
Control of the peroxisomal -oxidation pathway by a novel family of nuclear hormone receptors
-
Dreyer, C., et al. Control of the peroxisomal -oxidation pathway by a novel family of nuclear hormone receptors. Cell 68, 879-87 (1992).
-
(1992)
Cell
, vol.68
, pp. 879-887
-
-
Dreyer, C.1
-
14
-
-
0030835678
-
The organization, promoter analysis, expression of the human PPARgamma gene
-
Fajas, L., et al. The organization, promoter analysis, expression of the human PPARgamma gene. J Biol Chem 272, 18779-89 (1997).
-
(1997)
J Biol Chem
, vol.272
, pp. 18779-18789
-
-
Fajas, L.1
-
15
-
-
33747777758
-
PPARgamma as a new therapeutic target in inflammatory bowel diseases
-
Dubuquoy, L., et al. PPARgamma as a new therapeutic target in inflammatory bowel diseases. Gut 55, 1341-9 (2006).
-
(2006)
Gut
, vol.55
, pp. 1341-1349
-
-
Dubuquoy, L.1
-
16
-
-
0033152206
-
Loss-of-function mutations in PPAR gamma associated with human colon cancer
-
Sarraf, P., et al. Loss-of-function mutations in PPAR gamma associated with human colon cancer. Mol. Cell 3, 799-804 (1999).
-
(1999)
Mol. Cell
, vol.3
, pp. 799-804
-
-
Sarraf, P.1
-
17
-
-
0347756655
-
Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPARgamma and RelA
-
Kelly, D., et al. Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPARgamma and RelA. Nat. Immunol. 5, 104-12 (2004).
-
(2004)
Nat. Immunol.
, vol.5
, pp. 104-112
-
-
Kelly, D.1
-
18
-
-
33846542071
-
Mechanisms underlying the resistance to diet-induced obesity in germ-free mice
-
Backhed, F., Manchester, J. K., Semenkovich, C. F., Gordon, J. I. Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proc Natl Acad Sci USA 104, 979-84 (2007).
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 979-984
-
-
Backhed, F.1
Manchester, J.K.2
Semenkovich, C.F.3
Gordon, J.I.4
-
19
-
-
0034742533
-
-
Wada, K., Nakajima, A., Blumberg, R. S. and inflammatory bowel disease: a new therapeutic PPAR target for ulcerative colitis and Crohn's disease. 7, 329-31 (2001).
-
(2001)
And Inflammatory Bowel Disease: A New Therapeutic PPAR Target for Ulcerative Colitis and Crohn's Disease.
, vol.7
, pp. 329-331
-
-
Wada, K.1
Nakajima, A.2
Blumberg, R.S.3
-
20
-
-
0031671246
-
Differentiation and reversal of malignant changes in colon cancer through PPAR
-
Sarraf, P., Mueller, E., Jones, D. Differentiation and reversal of malignant changes in colon cancer through PPAR. Nat. Med. 4, 1046-52 (1998).
-
(1998)
Nat. Med.
, vol.4
, pp. 1046-1052
-
-
Sarraf, P.1
Mueller, E.2
Jones, D.3
-
21
-
-
32944454770
-
PPARgamma and colon and rectal cancer: Associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States)
-
Slattery, M. L., et al. PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States). Cancer Causes Control 17, 239-49 (2006).
-
(2006)
Cancer Causes Control
, vol.17
, pp. 239-249
-
-
Slattery, M.L.1
-
22
-
-
34250803903
-
Fat poetry: A kingdom for PPAR gamma
-
Anghel, S. I., Wahli, W. Fat poetry: a kingdom for PPAR gamma. Cell Res. 17, 486-511 (2007).
-
(2007)
Cell Res.
, vol.17
, pp. 486-511
-
-
Anghel, S.I.1
Wahli, W.2
-
23
-
-
80052667808
-
Identification of NF- B Modulation Capabilities within Human Intestinal Commensal Bacteria
-
Lakhdari, O., et al. Identification of NF- B Modulation Capabilities within Human Intestinal Commensal Bacteria. J. Biomed. Biotechnol. 2011, 282356 (2011).
-
(2011)
J. Biomed. Biotechnol.
, vol.2011
, pp. 282356
-
-
Lakhdari, O.1
-
24
-
-
84871667241
-
Butyrate produced by commensal bacteria potentiates phorbol esters induced AP-1 response in human intestinal epithelial cells
-
Nepelska, M., et al. Butyrate Produced by Commensal Bacteria Potentiates Phorbol Esters Induced AP-1 Response in Human Intestinal Epithelial Cells. PLoS One 7, e52869 (2012).
-
(2012)
PLoS One
, vol.7
, pp. e52869
-
-
Nepelska, M.1
-
25
-
-
84878662294
-
ANGPTL4 expression induced by butyrate and rosiglitazone in human intestinal epithelial cells utilizes independent pathways
-
Korecka, A., et al. ANGPTL4 expression induced by butyrate and rosiglitazone in human intestinal epithelial cells utilizes independent pathways. Am. J. Physiol. Gastrointest. Liver Physiol. 304, G1025-37 (2013).
-
(2013)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.304
, pp. G1025-G1037
-
-
Korecka, A.1
-
26
-
-
79955579989
-
The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon
-
Donohoe, D. R., et al. The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon. Cell Metab. 13, 517-26 (2011).
-
(2011)
Cell Metab.
, vol.13
, pp. 517-526
-
-
Donohoe, D.R.1
-
27
-
-
84875258449
-
Short chain fatty acids stimulate Angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating PPAR
-
Alex, S., et al. Short chain fatty acids stimulate Angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating PPAR. Mol. Cell. Biol. 33, 1303-16 (2013).
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 1303-1316
-
-
Alex, S.1
-
28
-
-
34447540228
-
Fecal water as a non-invasive biomarker in nutritional intervention: Comparison of preparation methods and refinement of different endpoints
-
Klinder, A., et al. Fecal water as a non-invasive biomarker in nutritional intervention: comparison of preparation methods and refinement of different endpoints. Nutr. Cancer 57, 158-67 (2007).
-
(2007)
Nutr. Cancer
, vol.57
, pp. 158-167
-
-
Klinder, A.1
-
29
-
-
0023276469
-
Short chain fatty acids in human large intestine, portal, hepatic and venous blood
-
Cummings, J. H., Pomare, E. W., Branch, W. J., Naylor, C. P., Macfarlane, G. T. Short chain fatty acids in human large intestine, portal, hepatic and venous blood. Gut 28, 1221-7 (1987).
-
(1987)
Gut
, vol.28
, pp. 1221-1227
-
-
Cummings, J.H.1
Pomare, E.W.2
Branch, W.J.3
Naylor, C.P.4
MacFarlane, G.T.5
-
30
-
-
8144226856
-
The gut microbiota as an environmental factor that regulates fat storage
-
Backhed, F., et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci USA 101, 15718-23 (2004).
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15718-15723
-
-
Backhed, F.1
-
31
-
-
41149098050
-
Enterococcus faecalis from newborn babies regulate endogenous PPARgamma activity and IL-10 levels in colonic epithelial cells
-
Are, A., et al. Enterococcus faecalis from newborn babies regulate endogenous PPARgamma activity and IL-10 levels in colonic epithelial cells. Proc. Natl. Acad. Sci. USA 105, 1943-8 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 1943-1948
-
-
Are, A.1
-
32
-
-
34547589477
-
Modulation of PPAR activity via phosphorylation
-
Burns, K. A., Vanden Heuvel, J. P. Modulation of PPAR activity via phosphorylation. Biochim. Biophys. Acta 1771, 952-60 (2007).
-
(2007)
Biochim. Biophys. Acta
, vol.1771
, pp. 952-960
-
-
Burns, K.A.1
Vanden Heuvel, J.P.2
-
33
-
-
38849190556
-
Gut microbiota: A potential new territory for drug targeting
-
Jia, W., Li, H., Zhao, L., Nicholson, J. K. Gut microbiota: a potential new territory for drug targeting. Nat Rev Drug Discov 7, 123-9 (2008).
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 123-129
-
-
Jia, W.1
Li, H.2
Zhao, L.3
Nicholson, J.K.4
-
34
-
-
84881543546
-
Human intestinal metagenomics: State of the art and future
-
Blottière, H. M., de Vos, W. M., Ehrlich, S. D., Doré, J. Human intestinal metagenomics: state of the art and future. Curr. Opin. Microbiol. 16, 232-9 (2013).
-
(2013)
Curr. Opin. Microbiol.
, vol.16
, pp. 232-239
-
-
Blottière, H.M.1
De Vos, W.M.2
Ehrlich, S.D.3
Doré, J.4
-
35
-
-
0032740993
-
Modulating nuclear receptor function: May the phos be with you
-
Shao, D., Lazar, M. A. Modulating nuclear receptor function: may the phos be with you. J. Clin. Invest. 103, 1617-8 (1999).
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1617-1618
-
-
Shao, D.1
Lazar, M.A.2
-
36
-
-
84934444916
-
Phosphorylation control of nuclear receptors
-
Laleveé, S., Ferry, C., Rochette-Egly, C. Phosphorylation control of nuclear receptors. Methods Mol. Biol. 647, 251-66 (2010).
-
(2010)
Methods Mol. Biol.
, vol.647
, pp. 251-266
-
-
Laleveé, S.1
Ferry, C.2
Rochette-Egly, C.3
-
37
-
-
0031057517
-
Transcriptional activation by peroxisome proliferator-activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site
-
Adams, M., Reginato, M. J., Shao, D., Lazar, M. A., Chatterjee, V. K. Transcriptional activation by peroxisome proliferator-activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site. J. Biol. Chem. 272, 5128-32 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 5128-5132
-
-
Adams, M.1
Reginato, M.J.2
Shao, D.3
Lazar, M.A.4
Chatterjee, V.K.5
-
38
-
-
0029775642
-
Insulin-and mitogen-activated protein kinase-mediated phosphorylation and activation of peroxisome proliferatoractivated receptor gamma
-
Zhang, B., et al. Insulin-and mitogen-activated protein kinase-mediated phosphorylation and activation of peroxisome proliferatoractivated receptor gamma. J. Biol. Chem. 271, 31771-4 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31771-31774
-
-
Zhang, B.1
-
39
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
-
Marshall, C. J. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80, 179-85 (1995).
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
40
-
-
0028935270
-
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
-
Raingeaud, J., et al. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270, 7420-6 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7420-7426
-
-
Raingeaud, J.1
-
41
-
-
77958615207
-
Decreased fat storage by Lactobacillus paracasei is associated with increased levels of angiopoietin-like 4 protein (ANGPTL4)
-
Aronsson, L., et al. Decreased fat storage by Lactobacillus paracasei is associated with increased levels of angiopoietin-like 4 protein (ANGPTL4). PLoS One 5 (2010).
-
(2010)
PLoS One
, vol.5
-
-
Aronsson, L.1
-
42
-
-
0035794293
-
Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies
-
Desreumaux, P., et al. Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies. J. Exp. Med. 193, 827-38 (2001).
-
(2001)
J. Exp. Med.
, vol.193
, pp. 827-838
-
-
Desreumaux, P.1
-
43
-
-
0032746173
-
A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response
-
Su, C. G., et al. A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response. J. Clin. Invest. 104, 383-9 (1999).
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 383-389
-
-
Su, C.G.1
-
44
-
-
33746159991
-
Peroxisome proliferator activated receptor gamma in colonic epithelial cells protects against experimental inflammatory bowel disease
-
Adachi, M., et al. Peroxisome proliferator activated receptor gamma in colonic epithelial cells protects against experimental inflammatory bowel disease. Gut 55, 1104-13 (2006).
-
(2006)
Gut
, vol.55
, pp. 1104-1113
-
-
Adachi, M.1
-
45
-
-
84867391121
-
PPAR in inflammatory bowel disease
-
Annese, V., Rogai, F., Settesoldi, A., Bagnoli, S. PPAR in Inflammatory Bowel Disease. PPAR Res. 2012, 620839 (2012).
-
(2012)
PPAR Res.
, vol.2012
, pp. 620839
-
-
Annese, V.1
Rogai, F.2
Settesoldi, A.3
Bagnoli, S.4
-
46
-
-
79955756026
-
Polymorphisms in NF- B, PXR, LXR, PPAR and risk of inflammatory bowel disease
-
Andersen, V., et al. Polymorphisms in NF- B, PXR, LXR, PPAR and risk of inflammatory bowel disease. World J. Gastroenterol. 17, 197-206 (2011).
-
(2011)
World J. Gastroenterol.
, vol.17
, pp. 197-206
-
-
Andersen, V.1
-
47
-
-
84887323708
-
Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis
-
Scher, J. U., et al. Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis. Elife 2, e01202 (2013).
-
(2013)
Elife
, vol.2
, pp. e01202
-
-
Scher, J.U.1
-
48
-
-
0038050412
-
New bacterial species associated with chronic periodontitis
-
Kumar, P. S., et al. New bacterial species associated with chronic periodontitis. J. Dent. Res. 82, 338-44 (2003).
-
(2003)
J. Dent. Res.
, vol.82
, pp. 338-344
-
-
Kumar, P.S.1
-
49
-
-
84863472497
-
A Crypt-Specific Core Microbiota Resides in the Mouse Colon
-
Pédron, T., et al. A Crypt-Specific Core Microbiota Resides in the Mouse Colon. mBio 3, 00116-12 (2012).
-
(2012)
MBio
, vol.3
, pp. 00116-00212
-
-
Pédron, T.1
-
51
-
-
84929207621
-
Commensal streptococcus salivarius modulates PPAR transcriptional activity in human intestinal epithelial cells
-
Couvigny, B., et al. Commensal Streptococcus salivarius Modulates PPAR Transcriptional Activity in Human Intestinal Epithelial Cells. PLoS One 10, e0125371 (2015).
-
(2015)
PLoS One
, vol.10
, pp. e0125371
-
-
Couvigny, B.1
|