Gingival recession and root caries in the ageing population: a critical evaluation of treatments

Journal of Clinical Periodontology

Volumn 44, Issue , 2017, Pages S178-S193

  Heasman, Peter A ^a   Ritchie, Mark ^b   Asuni, Abisola ^b   Gavillet, Erika ^a   Simonsen, Janne L ^c   Nyvad, Bente ^c  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE DENTAL HOSPITAL   (United Kingdom)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

ageing population; atraumatic restorative treatment; gingival recession; operative treatment; periodontal surgery; prevention; root caries

Indexed keywords

AGED; DENTAL CARIES; GINGIVA DISEASE; HUMAN;

AGED; GINGIVAL RECESSION; HUMANS; ROOT CARIES;

EID: 85014727699     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/jcpe.12676     Document Type: Article

References (127)

1. Abdellatif, H. M. & Burt, B. A. (1987) An epidemiological investigation into the relative importance of age and oral hygiene status as determinants of periodontitis. Journal of Dental Research 66, 13–18.
2. Adult Dental Health Survey UK. (2009) Summary report and thematic series. Available at: http://content.digital.nhs.uk/catalogue/PUB01086 Accessed 30.09.16.
3. Aichelmann-Reidy, M. E., Yukna, R. A., Evans, G. H., Nasr, H. F. & Mayer, E. T. (2001) Clinical evaluation of acellular allograft dermis for the treatment of human gingival recession. Journal of Periodontology 72, 998–1005.
4. Ainamo, A., Ainamo, J. & Poikkeus, R. (1981) Continuous widening of the band of attached gingiva from 23 to 65 years of age. Journal of Periodontal Research 16, 595–599.
5. Ainamo, J. & Talari, A. (1976) The increase with age of the width of attached gingiva. Journal of Periodontal Research 11, 182–188.
6. Albander, J. M. & Kingman, A. (1999) Gingival recession, gingival bleeding, and dental calculus in adults 30 years of age and older in the United States, 1988–1994. Journal of Periodontology 70, 30–43.
7. Al-Hamdan, K., Eber, R., Sarment, D., Kowalski, C. & Wang, H.-L. (2003) Guided tissue regeneration-based root coverage: meta-analysis. Journal of Periodontology 74, 1520–1533.
8. Amer, R. S. & Kolker, J. L. (2013) Restoration of root surface caries in vulnerable elderly patients: a review of the literature. Special Care in Dentistry 33, 141–149.
9. Baker, P. & Spedding, C. (2002) The aetiology of gingival recession. Dental Update 29, 59–62.
10. Baysan, A., Lynch, E., Ellwood, R., Davies, R., Petersson, L. & Borsboom, P. (2001) Reversal of primary root caries using dentifrices containing 5,000 and 1,100 ppm fluoride. Caries Research 35, 41–46.
11. Bignozzi, I., Crea, A., Capri, D., Littarru, C., Lajolo, C. & Tatakis, D. N. (2014) Root caries: a periodontal perspective. Journal of Periodontal Research 49, 143–163.
12. Billings, R. J., Brown, L. R. & Kaster, A. G. (1985) Contemporary treatment strategies for root surface dental caries. Gerodontics 1, 20–27.
13. Bouchard, P., Etienne, D., Ouhayoun, J. P. & Nilveus, R. (1994) Subepithelial connective tissue grafts in the treatment of gingival recessions. A comparative study of 2 procedures. Journal of Periodontology 65, 929–936.
14. Brown, L. J., Brunelle, J. A. & Kingman, A. (1996) Periodontal status in the United States, 1998–1991: prevalence, extent and demographic variation. Journal of Dental Research 75, 672–683.
15. Burt, B. A. (1994) Periodontitis and aging: reviewing recent evidence. Journal of the American Dental Association 125, 273–279.
16. Buti, J., Baccini, M., Niera, M., LaMarca, M. & Pini-Prato, G. P. (2013) Bayesian network meta-analysis of root coverage procedures: ranking efficacy and identification of best treatment. Journal of Clinical Periodontology 40, 372–386.
17. Cairo, F., Nieri, M. & Pagliaro, U. (2014) Efficacy of periodontal plastic surgery procedures in the treatment of localised facial gingival recession. A systematic review. Journal of Clinical Periodontology 41(Suppl. 15), S44–S62.
18. Cairo, F., Pagliaro, U. & Nieri, M. (2008) Treatment of gingival recession with coronally-advanced flap procedures: a systematic review. Journal of Clinical Periodontology 35, 136–162.
19. Cairo, F., Rotundo, R., Miller, P. D. & Pini Prato, G. P. (2009) Root coverage aesthetic score: a system to evaluate the esthetic outcome of the treatment of gingival recession through the evaluation of clinical cases. Journal of Periodontology 80, 705–710.
20. Castellanos, A. T., de la Rosa, M. R., de la Garza, M. & Caffesse, R. G. (2006) Enamel matrix derivative and coronal flaps to cover marginal tissue recessions. Journal of Periodontology 77, 7–14.
21. Chalmers, J. M., Carter, K. D. & Spencer, A. J. (2002) Caries incidence and increments in community-living older adults with and without dementia. Gerodontology 19, 80–94.
22. Chambrone, L., Chambrone, D., Pustiglioni, F. E., Chambrone, L. A. & Lima, L. A. (2008) Can subepithelial connective tissue grafts be considered the gold standard procedure in the treatment of Miller class I and II recession-type defects? Journal of Dentistry 36, 659–671.
23. Chambrone, L., Chambrone, D., Pustiglioni, F. E., Chambrone, L. A. & Lima, L. A. (2009a) The influence of tobacco smoking on the outcomes achieved by root-coverage procedures. A systematic review. Journal of the American Dental Association 140, 294–306.
24. Chambrone, L., Faggion, C. M. Jr, Pannuti, C. M. & Chambrone, L. A. (2010a) Evidence-based periodontal plastic surgery: an assessment of quality of systematic reviews in the treatment of recession-type defects. Journal of Clinical Periodontology 37, 1110–1118.
25. Chambrone, L., Lima, L. A., Pustiglioni, F. E. & Chambrone, L. A. (2009b) Systematic review of periodontal plastic surgery in the treatment of multiple recession-type defects. Journal of the Canadian Dental Association 75, 203a–203f.
26. Chambrone, L., Pannuti, C. M., Tu, Y.-K. & Chambrone, L. A. (2012) Journal of Periodontology 83, 477–490.
27. Chambrone, L., Sukekava, F., Araújo, M. G., Pustiglioni, F. E., Chambrone, L. A. & Lima, L. A. (2009c) Root coverage procedures for the treatment of localised recession-type defects. The Cochrane Database of Systematic Reviews (2), CD007161. DOI: 10.1002/14651858. CD 007161.pub2.
28. Chambrone, L., Sukekava, F., Araújo, M. G., Pustiglioni, F. E., Chambrone, L. A. & Lima, L. A. (2010b) Root coverage procedures for the treatment of localised recession-type defects: a systematic review. Journal of Periodontology 81, 452–478.
29. Chambrone, L. & Tatakis, D. N. (2015) Periodontal soft tissue root coverage procedures: a systematic review from the AAP regeneration workshop. Journal of Periodontology 86(Suppl.), S8–S51.
30. Chen, X., Clark, J. J. J. & Naorungroj, S. (2013) Oral health in nursing home residents with different cognitive statuses. Gerontology 30, 49–60.
31. Cheng, Y.-F., Chen, J.-W., Lin, S.-J. & Lu, H.-K. (2007) Is coronally positioned flap procedure adjunct with enamel matrix derivative or root conditioning a relevant predictor for achieving root coverage? A systematic review. Journal of Periodontal Research 42, 474–485.
32. Clauser, C., Nieri, M., Franceschi, D., Pagliaro, U. & Pini-Prato, G. (2003) Evidence-based mucogingival therapy. Part 2: Ordinary and individual patient data meta-analyses of surgical treatment of recession using complete root coverage as the outcome variable. Journal of Periodontology 74, 741–756.
33. Da Mata, C., Allen, P. F., Cronin, M., O′Mahony, D., McKenna, G. & Woods, N. (2014) Cost-effectiveness of ART restorations in elderly adults: a randomized clinical trial. Community Dentistry and Oral Epidemiology 42, 79–87.
34. DePaola, P. (1993) Caries in our aging population: What are we learning? In: Bowen, W. H. & Tabak, L. A. (eds). Cariology for the Nineties, pp. 25–35. Rochester, NY, USA: University of Rochester Press.
35. DePaola, P. F., Soparkar, P. M., Tavares, M. & Kent, R. L. Jr (1989) Clinical profiles of individuals with and without root surface caries. Gerodontology 8, 9–15.
36. Deutsch, A. (2016) An alternate technique of care using silver fluoride followed by stannous fluoride in the management of root caries in aged care. Special Care in Dentistry 36, 85–92.
37. Dijkman, A., Huizinga, E., Ruben, J. & Arends, J. (1990) Remineralization of human enamel in situ after 3 months: the effect of not brushing versus the effect of an F dentifrice and an F-free dentifrice. Caries Research 24, 263–266.
38. Duane, B. (2011) Limited evidence of the effect of chlorhexidine varnish (CHX-V) on root caries. Evidence-based Dentistry 12, 39–40.
39. Ekstrand, K., Martignon, S. & Holm-Pedersen, P. (2008) Development and evaluation of two root caries controlling programmes for home-based frail people older than 75 years. Gerodontology 25, 67–75.
40. Ekstrand, K. R., Poulsen, J. E., Hede, B., Twetman, S., Qvist, V. & Ellwood, R. P. (2013) A randomized clinical trial of the anti-caries efficacy of 5,000 compared to 1,450 ppm fluoridated toothpaste on root caries lesions in elderly disabled nursing home residents. Caries Research 47, 391–398.
41. Ellefsen, B., Holm-Pedersen, P., Morse, D. E., Schroll, M., Andersen, B. B. & Waldemar, G. (2008) Caries prevalence in older persons with and without dementia. Journal of the American Geriatrics Society 56, 59–67.
42. Emilson, C. G., Ravald, N. & Birkhed, D. (1993) Effects of a 12-month prophylactic programme on selected oral bacterial populations on root surfaces with active and inactive carious lesions. Caries Research 27, 195–200.
43. Fejerskov, O. (1994) Recent advancements in the treatment of root surface caries. International Dental Journal 44, 139–144.
44. Fejerskov, O., Luan, W. M., Nyvad, B., Budtz-Jørgensen, E. & Holm-Pedersen, P. (1991) Active and inactive root surface caries lesions in a selected group of 60- to 80-year-old Danes. Caries Research 25, 385–391.
45. Ferro, R., Besostri, A., Strohmenger, L., Mazzucchelli, L., Paoletti, G., Senna, A., Stellini, E. & Mazzoleni, S. (2008) Oral health problems and needs in nursing home residents in Northern Italy. Community Dental Health 25, 231–236.
46. Frencken, J. E. (2014) The atraumatic restorative treatment (ART) approach can improve oral health for the elderly; myth or reality? Gerontology 31, 81–82.
47. Fuller, E., Steele, J., Watt, R. & Nuttall, N. (2011) Oral health and function – a report from the Adult Dental Health Survey 2009. Available at: http://www.hscic.gov.uk/catalogue/PUB01086/adul-dent-heal-surv-summ-them-the1-2009-rep3.pdf Accessed June 2016.
48. Fung, M. H. T., Wong, M. C. M., Lo, E. C. M. & Chu, C. H. (2013) Arresting early childhood caries with silver diammine fluoride – a literature review. Oral Hygiene & Health 1, 117.
49. Fure, S. & Zickert, I. (1990) Prevalence of root surface caries in 55, 65, and 75-year-old Swedish individuals. Community Dentistry and Oral Epidemiology 18, 100–105.
50. Furseth, R. (1970) A study of experimentally exposed and fluoride treated dental cementum in pigs. Acta Odontologica Scandinavica 28, 833–850.
51. Gapski, R., Parks, C. A. & Wang, H. L. (2005) Acellular dermal matrix for mucogingival surgery: a meta-analysis. Journal of Periodontology 76, 1814–1822.
52. Gil-Montoya, J. A., Mateos-Palacios, R., Bravo, M., González-Moles, M. A. & Pulgar, R. (2014) Atraumatic restorative treatment and Carisolv use for root caries in the elderly: 2-year follow-up randomized clinical trial. Clinical Oral Investigations 18, 1089–1095.
53. Gluzman, R., Katz, R. V., Frey, B. J. & McGowan, R. (2013) Prevention of root caries: a literature review of primary and secondary preventive agents. Special Care in Dentistry 33, 133–140.
54. Gonzales, A. C. C. & Zuluaga, D. J. M. (2016) Clinical outcome of root caries restorations using ART and rotary techniques in institutionalized elders. Brazilian Oral Research 30, doi:10.1590/1807-3107BOR-2016.vol30.0063.
55. Graziani, F., Gennai, S., Roldán, S., Discepoli, N., Buti, J., Madianos, P. & Herrera, D. (2014) Efficacy of plastic procedures in the treatment of multiple gingival recessions. Journal of Clinical Periodontology 41, S63–S76.
56. Griffin, S. O., Regnier, E., Griffin, P. M. & Huntley, V. (2007) Effectiveness of fluoride in preventing caries in adults. Journal of Dental Research 86, 410–415.
57. Guivante-Nabet, C., Tavernier, J. C., Trevoux, M., Berenholc, C. & Berdal, A. (1998) Active and inactive caries lesions in a selected elderly institutionalised French population. International Dental Journal 48, 111–122.
58. Hofmänner, P., Alessandri, R., Laugisch, O., Aroca, S., Salvi, G. E., Stavropoulos, A. & Sculean, A. (2012) Predictability of surgical techniques used for coverage of multiple adjacent gingival recessions – a systematic review. Quintessence International 43, 545–554.
59. Hu, J. Y., Chen, X. C., Li, Y. Q., Smales, R. J. & Yip, K. H. (2005) Radiation-induced root surface caries restored with glass-ionomer cement placed in conventional and ART cavity preparations: results after two years. Australian Dental Journal 50, 186–190.
60. Hwang, D. & Wang, H.-L. (2006) Flap thickness as a predictor of root coverage: a systematic Review. Journal of Periodontology 77, 1625–1634.
61. Jepsen, S., Ayna, M., Hedderich, J. & Eberhard, J. (2004) Significant influence of scaler tip design on root substance loss resulting from ultrasonic scaling: a laserprofilometric in vitro study. Journal of Clinical Periodontology 31, 1003–1006.
62. Johnson, G. & Almqvist, H. (2003) Non-invasive management of superficial root caries lesions in disabled and infirm patients. Gerodontology 20, 9–14.
63. Joshipura, K. J., Kent, R. L. & DePaola, P. F. (1994) Gingival recession: intra-oral distribution and associated factors. Journal of Periodontology 65, 864–871.
64. Karam, P. S. B. H., Sant'Ana, A. C. P., de Rezende, M. L. R., Greghi, S. L. A., Damante, C. A. & Zangrando, M. S. R. (2015) Root surface modifiers and subepithelial connective tissue graft for treatment of gingival recessions: a systematic review. Journal of Periodontal Research 51, 175–185.
65. Katz, R. V., Hazen, S. P., Chilton, N. W. & Mumma, R. D. Jr (1982) Prevalence and intraoral distribution of root caries in an adult population. Caries Research 16, 265–271.
66. Khan, K. S., ter Riet, G., Glanville, J., Sowden, A. J. & Kleijnen, J. (eds) (2011) Undertaking Systematic Reviews of Research on Effectiveness: CRD's Guidance for those Carrying Out or Commissioning Reviews (CRD Report Number 4), 2nd edition. York, UK: NHS Centre for Reviews and Dissemination, University of York, 2001. ISBN 1 900640 20 1.
67. Khocht, A., Simon, G., Person, P. & Denepitiya, J. L. (1993) Gingival recession in relation to history of hard toothbrush use. Journal of Periodontology 64, 900–905.
68. Kidd, E., Fejerskov, O. & Nyvad, B. (2015) Infected dentine revisited. Dental Update 42, 808–809.
69. Kirkegaard, E., Borgnakke, W. S. & Grønbæk, L. (1986) Tandsygdomme, behandlingsbehov og tandplejevaner hos et repræsentativt udsnit af den voksne danske befolkning: (voksenundersøgelsen). p. 581, Aarhus, Denmark: Århus Tandlægehøjskole.
70. Kitchen, P. (1941) The prevalence of tooth root exposure, and the relation of the extent of such exposure to the degree of abrasion in different age classes. Journal of Dental Research 20, 565–581.
71. Ko, H.-Y. & Lu, H.-K. (2010) Systematic review of the clinical performance of connective tissue graft and guided tissue regeneration in the treatment of gingival recessions of Miller's classification grades I and II. Journal of Experimental Clinical Medicine 2, 63–71.
72. Koop, R., Merheb, J. & Quirynen, M. (2012) Periodontal regeneration with enamel matrix derivative in reconstructive periodontal therapy: a systematic review. Journal of Periodontology 83, 707–720.
73. Leake, J. L. (2001) Clinical decision-making for caries management in root surfaces. Journal of Dental Education 65, 1147–1153.
74. Levy, S. M. & Jensen, M. E. (1990) A clinical evaluation of the restoration of root surface caries. Special Care Dentistry 10, 156–160.
75. Li, R., Lo, E. C. M., Liu, B. Y., Wong, M. C. M. & Chu, C. H. (2016) Randomized clinical trial on arresting dental root caries through silver diamine fluoride applications in community-dwelling elders. Journal of Dentistry 51, 15–20. doi:10.1016/j.dent.201605.005.
76. Litonjua, L. A., Andreana, S. & Cohen, R. E. (2005) Toothbrush abrasions and noncarious cervical lesions: evolving concepts. Compendium of Continuing Education in Dentistry 26, 767–768, 770-774, 776.
77. Lo, E. C. M., Loy, Y., Tan, H. P., Dyson, J. E. & Corbet, E. F. (2006) ART and conventional root restorations in elders after 12 months. Journal of Dental Research 85, 929–932.
78. Locker, D., Slade, G. D. & Murray, H. (1998) Epidemiology of periodontal disease among older adults: a review. Periodontology 2000 16, 16–33.
79. Löe, H., Ǻnerud, Ǻ. & Boysen, H. (1992) The natural history of periodontal disease in man: prevalence, severity and extent of gingival recession. Journal of Periodontology 63, 489–495.
80. Löe, H., Ǻnerud, Ǻ., Boysen, H. & Smith, M. (1978) The natural history of periodontal disease in man: the rate of periodontal destruction before 40 years of age. Journal of Periodontology 49, 607–620.
81. Luo, H. Y., Li, R. M., Wang, C. L., Peng, L. & Ye, L. (2015) The adjunctive use of platelet concentrates in the therapy of gingival recessions: a systematic review and meta-analysis. Journal of Oral Rehabilitation 42, 552–561.
82. Marinho, V. C., Higgins, J. P., Sheiham, A. & Logan, S. (2003) Fluoride toothpastes for preventing dental caries in children and adolescents. Cochrane Database of Systematic Reviews (1), Cd002278, doi:10.1002/14651858.cd002278.
83. Moraschini, V. & dos Santos Porto Barboza, E. (2016) Use of platelet-rich fibrin membrane in the treatment of gingival recession: a systematic review and meta-analysis. Journal of Periodontology 87, 281–290.
84. Needleman, I. (2015) Aging and the periodontium. In: Newman, M. G., Takei, H. H., Klokkevold, P. R. & Carranza, F. A. (eds). Carranza's Clinical Periodontology, 12th edition, pp. 40–44, Philadelphia: Elsevier Saunders.
85. Nyvad, B. & Fejerskov, O. (1982) Root surface caries: clinical, histopathological and microbiological features and clinical implications. International Dental Journal 32, 311–326.
86. Nyvad, B. & Fejerskov, O. (1986) Active root surface caries converted into inactive caries as a response to oral hygiene. Scandinavian Journal of Dental Research 94, 281–284.
87. Nyvad, B. & Fejerskov, O. (2015) The caries control concept. In: Fejerskov, O., Nyvad, B. & Kidd, E. (eds). Dental Caries: The Disease and its Clinical Management, 3rd edition, pp. 235–243. Oxford: Wiley Blackwell.
88. Nyvad, B. & Kidd, E. A. M. (2015) The principles of caries control for the individual patient. In: Fejerskov, O., Nyvad, B. & Kidd, E. (eds). Dental Caries: The Disease and its Clinical Management, 3rd edition, pp. 303–320. Oxford: Wiley Blackwell.
89. Nyvad, B., ten Cate, J. M. & Fejerskov, O. (1997) Arrest of root surface caries in situ. Journal of Dental Research 76, 1845–1853.
90. Oates, T. W., Robinson, M. & Gunsolley, J. C. (2003) Surgical therapies for the treatment of gingival recession. A systematic review. Annals of Periodontology 8, 303–320.
91. Oliveira, G. H. & Muncinelli, E. A. (2012) Efficacy of root surface biomodification in root coverage: a systematic review. Journal of the Canadian Dental Association 78, c122.
92. Oxman, A. D. & Guyatt, G. H. (1991) Validation of an index of the quality of review articles. Journal of Clinical Epidemiology 44, 1271–1278.
93. Page, R. C. & Beck, J. D. (1997) Risk assessment for periodontal diseases. International Dental Journal 47, 61–87.
94. Pagliaro, U., Nieri, M., Franceschi, D., Clauser, C. & Pini-Prato, G. (2003) Evidence-based mucogingival therapy. Part 1: A critical review of the literature on root coverage procedures. Journal of Periodontology 74, 709–740.
95. Papapanou, P. N., Lindhe, J., Sterrett, J. D. & Eneroth, L. (1991) Considerations on the contribution of ageing to loss of periodontal tissue support. Journal of Clinical Periodontology 18, 611–615.
96. Ravald, N. & Birkhed, D. (1992) Prediction of root caries in periodontally treated patients maintained with different fluoride programmes. Caries Research 26, 450–458.
97. Roccuzzo, M., Bunino, M., Needleman, I. & Sanz, M. (2002a) Periodontal plastic surgery for treatment of localised gingival recessions: a systematic review. Journal of Clinical Periodontology 29 (Suppl. 3), 178–194.
98. Roccuzzo, M., Bunino, M., Needleman, I. & Sanz, M. (2002b) Periodontal plastic surgery for treatment of localised gingival recessions: a systematic review. Journal of Clinical Periodontology 29, 178–194.
99. Rodrigues, J. A., Lussi, A., Seemann, R. & Neuhaus, K. W. (2011) Prevention of crown and root caries in adults. Periodontology 2000 55, 231–249.
100. Rosenblatt, A., Stamford, T. C. & Niederman, R. (2009) Silver diamine fluoride: a caries “silver-fluoride bullet”. Journal of Dental Research 88, 116–125.
101. Rosetti, E. P., Marcantonio, R. A., Rossa, C. Jr, Chaves, E. S., Goisis, G. & Marcantonio, E. Jr (2000) Journal of Periodontology 71, 1417–1441.
102. Salonen, L., Allander, L., Bratthall, D., Togelius, J. & Hellden, L. (1989) Oral health status in an adult Swedish population. Prevalence of caries. A cross-sectional epidemiological study in the Northern Alvsborg county. Swedish Dental Journal 13, 111–123.
103. Sangnes, G. & Gjermo, P. (1976) Prevalence of oral soft tissue and hard tissue lesions related to mechanical toothcleansing procedures. Community Dentistry & Oral Epidemiology 4, 77–83.
104. Sarfati, A., Bourgeois, D., Katsahian, S., Mora, F. & Bouchard, P. (2010) Risk assessment for buccal gingival recession defects in an adult population. Journal of Periodontology 81, 1419–1425.
105. Selvig, K. A. (1969) The formation of plaque and calculus on recently exposed tooth surfaces. Journal of Periodontal Research 4, S10–S11.
106. Serino, G., Wennstrom, J. L., Lindhe, J. & Eneroth, L. (1994) The prevalence and distribution of gingival recession in subjects with a high standard of oral hygiene. Journal of Clinical Periodontology 21, 57–63.
107. Shea, B. J., Grimshaw, J. M., Wells, G. A., Boers, M., Andersson, M., Hamel, C., Porter, A. C., Tugwell, P., Moher, D. & Bouter, L. M. (2007) Development of AMSTAR: a measurement to assess the methodological quality of systematic reviews. BMC Medical Research Methodology 7, 10–15.
108. Simunkovic, S. K., Boras, V. V., Panduric, J. & Zilic, I. A. (2005) Oral health among institutionalised elderly in Zagreb, Croatia. Gerodontology 22, 238–241.
109. Slot, D. E., Vaandrager, N. C., Van Loveren, C., Van Palenstein Helderman, W. H. & Van der Weijden, G. A. (2011) The effect of chlorhexidine varnish on root caries: a systematic review. Caries Research 45, 162–173.
110. Srinivasan, M., Schimmel, M., Riesen, M., Ilgner, A., Wicht, M. J., Warncke, M., Ellwood, R. P., Nitschke, I., Muller, F. & Noack, M. J. (2014) High-fluoride toothpaste: a multicenter randomized controlled trial in adults. Community Dentistry and Oral Epidemiology 42, 333–340.
111. Steele, J. G., Treasure, E., Pitts, N. B., Morris, J. & Bradnock, G. (2000) Total tooth loss in the United Kingdom in 1998 and implications for the future. British Dental Journal 189, 598–603.
112. Takahashi, N. & Nyvad, B. (2011) The role of bacteria in the caries process: ecological perspectives. Journal of Dental Research 90, 294–303.
113. Takahashi, N. & Nyvad, B. (2016) Ecology of dentin and root caries. Caries Research 50, 422–431.
114. Tan, H. P., Lo, E. C., Dyson, J. E., Luo, Y. & Corbet, E. F. (2010) A randomized trial on root caries prevention in elders. Journal of Dental Research 89, 1086–1090.
115. Twetman, S. (2004) Antimicrobials in future caries control? A review with special reference to chlorhexidine treatment. Caries Research 38, 223–229.
116. Twetman, S., Petersson, L. G., Axelsson, S., Dahlgren, H., Holm, A.-K., Källestål, C., Lagerlöf, F., Lingström, P., Mejàre, I., Nordenram, G., Norlund, A. & Söder, B. (2004) Caries-preventive effect of sodium fluoride mouthrinses: a systematic review of controlled clinical trials. Acta Odontologica Scandinavica 62, 223–239.
117. Vehkalahti, M. M., Vrbic, V. L., Peric, L. M. & Matvoz, E. S. (1997) Oral hygiene and root caries occurrence in Slovenian adults. International Dental Journal 47, 26–31.
118. Vernazza, C., Heasman, P. A., Gaunt, F. & Pennington, M. (2012) How to measure the cost-effectiveness of periodontal treatments. Periodontology 2000, 60, 138–146.
119. Vigild, M. (1989) Dental caries and the need for treatment among institutionalized elderly. Community Dentistry and Oral Epidemiology 17, 102–105.
120. Wallace, M. C., Retief, D. H. & Bradley, E. L. Jr (1988) Prevalence of root caries in a population of older adults. Gerodontics 4, 84–89.
121. Walls, A. W. & Meurman, J. H. (2012) Approaches to caries prevention and therapy in the elderly. Advances in Dental Research 24, 36–40.
122. White, D., Pitts, N., Steele, J. G., Sadler, K. & Chadwick, B. (2011) Disease and Related Disorders – a report from the Adult Health Survey. URL http://www.hscic.gov.uk/catalogue/PUB01086/adul-dent-heal-surv-summ-them-the2-2009-rep4.pdf. [Accessed on 19th April 2016].
123. Wierichs, R. J. & Meyer-Lueckel, H. (2015) Systematic review on noninvasive treatment of root caries lesions. Journal of Dental Research 94, 261–271.
124. Wyatt, C. C. L. (2002) Elderly Canadians residing in long-term care hospitals: Part II. Dental caries status. Journal of the Canadian Dental Association 68, 359–363.
125. Wyatt, C. C. L. & MacEntee, M. I. (2004) Caries management for institutionalized elders using fluoride and chlorhexidine mouthrinses. Community Dentistry and Oral Epidemiology 32, 322–328.
126. Wyatt, C. C. L., Maupome, G., Hujoel, P. P., MacEntee, M. I., Persson, G. R., Persson, R. E. & Kiyak, H. A. (2007) Chlorhexidine and preservation of sound tooth structure in older adults. Caries Research 41, 93–101.
127. Zhang, W., McGrath, C., Lo, E. C. & Li, J. Y. (2013) Silver diamine fluoride and education to prevent and arrest root caries among community-dwelling elders. Caries Research 47, 284–290.