-
1
-
-
33746808398
-
Wnt/β-catenin signaling in development and disease
-
Clevers, H. (2006). Wnt/β-Catenin signaling in development and disease. Cell 127, 469-480
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
2
-
-
84861986053
-
Wnt/β-catenin signaling and disease
-
Clevers, H. and Nusse, R. (2012). Wnt/β-catenin signaling and disease. Cell 149, 1192-1205
-
(2012)
Cell
, vol.149
, pp. 1192-1205
-
-
Clevers, H.1
Nusse, R.2
-
3
-
-
0030978351
-
β-catenin is a target for the ubiquitin-proteasome pathway
-
Aberle, H., Bauer, A., Stappert, J., Kispert, A., and Kemler, R. (1997). β-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 16, 3797-3804
-
(1997)
EMBO J.
, vol.16
, pp. 3797-3804
-
-
Aberle, H.1
Bauer, A.2
Stappert, J.3
Kispert, A.4
Kemler, R.5
-
4
-
-
51149118892
-
Deciphering the function of canonical wnt signals in development and disease: Conditional loss- and gain-of-function mutations of β-catenin in mice
-
Grigoryan, T., Wend, P., Klaus, A., and Birchmeier, W. (2008). Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of β-catenin in mice. Genes Dev. 22, 2308-2341
-
(2008)
Genes Dev.
, vol.22
, pp. 2308-2341
-
-
Grigoryan, T.1
Wend, P.2
Klaus, A.3
Birchmeier, W.4
-
6
-
-
85014547357
-
The role of wnt signalling in vertebrate head induction and the organizergradient model dualism
-
(Kuehl M., ed.) Chapter 5, Landis Biosciences Publishing, Georgetown
-
Kiecker, C. and Niehrs, C. (2003) The role of Wnt signalling in vertebrate head induction and the organizergradient model dualism in Wnt Signaling in Development (Kuehl M., ed.) Chapter 5, Landis Biosciences Publishing, Georgetown
-
(2003)
Wnt Signaling in Development
-
-
Kiecker, C.1
Niehrs, C.2
-
7
-
-
0024435879
-
Ectopic expression of the protooncogene int-1 in xenopus embryos leads to duplication of the embryonic axis
-
McMahon, A.P. and Moon, R.T. (1989). Ectopic expression of the protooncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis. Cell 58, 1075-1084
-
(1989)
Cell
, vol.58
, pp. 1075-1084
-
-
McMahon, A.P.1
Moon, R.T.2
-
8
-
-
0026039487
-
Injected wnt RNA induces a complete body axis in xenopus embryos
-
Sokol, S., Christian, J.L., Moon, R.T., and Melton, D.A. (1991). Injected Wnt RNA induces a complete body axis in Xenopus embryos. Cell 67, 741-752
-
(1991)
Cell
, vol.67
, pp. 741-752
-
-
Sokol, S.1
Christian, J.L.2
Moon, R.T.3
Melton, D.A.4
-
9
-
-
0025932959
-
Injected xwnt-8 RNA acts early in xenopus embryos to promote formation of a vegetal dorsalizing center
-
Smith, W.C. and Harland, R.M. (1991). Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center. Cell 67, 753-765
-
(1991)
Cell
, vol.67
, pp. 753-765
-
-
Smith, W.C.1
Harland, R.M.2
-
10
-
-
20944435474
-
Wnt signaling: Multiple functions in neural development
-
Ille, F. and Sommer, L. (2005). Wnt signaling: multiple functions in neural development. Cell. Mol. Life Sci. 62, 1-9
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, pp. 1-9
-
-
Ille, F.1
Sommer, L.2
-
11
-
-
17844366846
-
WNTs in the vertebrate nervous system: From patterning to neuronal connectivity
-
Ciani, L. and Salinas, P.C. (2005). WNTs in the vertebrate nervous system: from patterning to neuronal connectivity. Nat. Rev. Neurosci. 6, 351-362
-
(2005)
Nat. Rev. Neurosci
, vol.6
, pp. 351-362
-
-
Ciani, L.1
Salinas, P.C.2
-
12
-
-
0035164395
-
A morphogen gradient of Wnt/βeta-catenin signalling regulates anteroposterior neural patterning in Xenopus
-
Kiecker, C and Niehrs, C. (2001). A morphogen gradient of Wnt/βeta-catenin signalling regulates anteroposterior neural patterning in Xenopus. Development 128, 4189-4201
-
(2001)
Development
, vol.128
, pp. 4189-4201
-
-
Kiecker, C.1
Niehrs, C.2
-
13
-
-
0031473787
-
Regulation of dorsal fate in the neuraxis by wnt-1 and wnt-3a
-
Saint-Jeannet, J.P., He, X., Varmus, H.E., and Dawid, I.B. (1997). Regulation of dorsal fate in the neuraxis by Wnt-1 and Wnt-3a. Proc. Natl. Acad. Sci. USA. 94, 13713-13718
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13713-13718
-
-
Saint-Jeannet, J.P.1
He, X.2
Varmus, H.E.3
Dawid, I.B.4
-
14
-
-
0036333208
-
A mitogen gradient of dorsal midline wnts organizes growth in the CNS
-
Megason, S.G. and McMahon, A.P. (2002). A mitogen gradient of dorsal midline Wnts organizes growth in the CNS. Development 129, 2087-2098
-
(2002)
Development
, vol.129
, pp. 2087-2098
-
-
Megason, S.G.1
McMahon, A.P.2
-
15
-
-
0028229495
-
Evidence for a mitogenic effect of wnt-1 in the developing Mammalian central nervous system
-
Dickinson, M.E., Krumlauf, R., and McMahon, A.P. (1994). Evidence for a mitogenic effect of Wnt-1 in the developing mammalian central nervous system. Development 120, 1453-1471
-
(1994)
Development
, vol.120
, pp. 1453-1471
-
-
Dickinson, M.E.1
Krumlauf, R.2
McMahon, A.P.3
-
16
-
-
0031591946
-
Wnt signalling required for expansion of neural crest and CNS progenitors
-
Ikeya, M., Lee, S.M.K., Johnson, J.E., McMahon, A.P., and Takada, S. (1997). Wnt signalling required for expansion of neural crest and CNS progenitors. Nature 389, 966-970
-
(1997)
Nature
, vol.389
, pp. 966-970
-
-
Ikeya, M.1
Lee, S.M.K.2
Johnson, J.E.3
McMahon, A.P.4
Takada, S.5
-
17
-
-
2342514254
-
Effects of wnt1 signaling on proliferation in the developing mid-/hindbrain region
-
Panhuysen, M., Vogt Weisenhorn, D.M., Blanquet, V., Brodski, C, Heinzmann, U., Beisker, W., and Wurst, W. (2004). Effects of Wnt1 signaling on proliferation in the developing mid-/hindbrain region. Mol. Cell. Neurosci. 26, 101-111
-
(2004)
Mol. Cell. Neurosci
, vol.26
, pp. 101-111
-
-
Panhuysen, M.1
Vogt Weisenhorn, D.M.2
Blanquet, V.3
Brodski, C.4
Heinzmann, U.5
Beisker, W.6
Wurst, W.7
-
18
-
-
33947319833
-
The zebrafish zic2a-zic5 gene pair acts downstream of canonical Wnt signaling to control cell proliferation in the developing tectum
-
Nyholm, M.K., Wu, S.F., Dorsky, R.I., and Grinblat, Y. (2007). The zebrafish zic2a-zic5 gene pair acts downstream of canonical Wnt signaling to control cell proliferation in the developing tectum. Development 134, 735-746
-
(2007)
Development
, vol.134
, pp. 735-746
-
-
Nyholm, M.K.1
Wu, S.F.2
Dorsky, R.I.3
Grinblat, Y.4
-
19
-
-
1642377931
-
The presence of FGF2 signaling determines whether β-catenin exerts effects on proliferation or neuronal differentiation of neural stem cells
-
Israsena, N, Hu, M., Fu, W., Kan, L., and Kessler, J.A. (2004). The presence of FGF2 signaling determines whether β-catenin exerts effects on proliferation or neuronal differentiation of neural stem cells. Dev. Biol. 268, 220-231
-
(2004)
Dev. Biol.
, vol.268
, pp. 220-231
-
-
Israsena, N.1
Hu, M.2
Fu, W.3
Kan, L.4
Kessler, J.A.5
-
20
-
-
84880682287
-
Wnt7a regulates multiple steps of neurogenesis
-
Qu, Q., Sun, G, Murai, K, Ye, P., Li, W., Asuelime, G, Cheung, Y.T., and Shi, Y. (2013). Wnt7a regulates multiple steps of neurogenesis. Mol. Cell. Biol. 33, 2551-2559
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 2551-2559
-
-
Qu, Q.1
Sun, G.2
Murai, K.3
Ye, P.4
Li, W.5
Asuelime, G.6
Cheung, Y.T.7
Shi, Y.8
-
21
-
-
0037829660
-
Canonical wnt signals are essential for homeostasis of the intestinal epithelium
-
Pinto, D., Gregorieff, A., Begthel, H., and Clevers, H. (2003). Canonical Wnt signals are essential for homeostasis of the intestinal epithelium. Genes Dev. 17, 1709-1713
-
(2003)
Genes Dev.
, vol.17
, pp. 1709-1713
-
-
Pinto, D.1
Gregorieff, A.2
Begthel, H.3
Clevers, H.4
-
22
-
-
84869864069
-
Redundant sources of wnt regulate intestinal stem cells and promote formation of paneth cells
-
Farin, H.F., Van Es, J.H., and Clevers, H. (2012). Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells. Gastroenterology 143, 1518-1529
-
(2012)
Gastroenterology
, vol.143
, pp. 1518-1529
-
-
Farin, H.F.1
Van Es, J.H.2
Clevers, H.3
-
23
-
-
80053907201
-
Canonical wnt signaling regulates hematopoiesis in a dosagedependent fashion
-
Luis, T.C., Naber, B.A., Roozen, P.P., Brugman, M.H., de Haas, E.F., Ghazvini, M., Fibbe, W.E., van Dongen, J.J., Fodde, R., and Staal, F.J. (2011). Canonical wnt signaling regulates hematopoiesis in a dosagedependent fashion. Cell Stem Cell 9, 345-356
-
(2011)
Cell Stem Cell
, vol.9
, pp. 345-356
-
-
Luis, T.C.1
Naber, B.A.2
Roozen, P.P.3
Brugman, M.H.4
De Haas, E.F.5
Ghazvini, M.6
Fibbe, W.E.7
Van Dongen, J.J.8
Fodde, R.9
Staal, F.J.10
-
24
-
-
69049096989
-
Genomic response to wnt signalling is highly context-dependent-evidence from DNA microarray and chromatin immunoprecipitation screens of wnt/TCF targets
-
Railo, A., Pajunen, A., Itaranta, P., Naillat, F., Vuoristo, J., Kilpelainen, P., and Vainio, S. (2009). Genomic response to Wnt signalling is highly context-dependent-evidence from DNA microarray and chromatin immunoprecipitation screens of Wnt/TCF targets. Exp. Cell Res. 315, 2690-2704
-
(2009)
Exp. Cell Res.
, vol.315
, pp. 2690-2704
-
-
Railo, A.1
Pajunen, A.2
Itaranta, P.3
Naillat, F.4
Vuoristo, J.5
Kilpelainen, P.6
Vainio, S.7
-
25
-
-
33845355511
-
Diversity of LEF/TCF action in development and disease
-
Arce, L., Yokoyama, N.N., and Waterman, M.L. (2006). Diversity of LEF/TCF action in development and disease. Oncogene 25, 7492-7504
-
(2006)
Oncogene
, vol.25
, pp. 7492-7504
-
-
Arce, L.1
Yokoyama, N.N.2
Waterman, M.L.3
-
26
-
-
36849023295
-
Differential control of wnt target genes involves epigenetic mechanisms and selective promoter occupancy by T-cell factors
-
Wohrle, S., Wallmen, B., and Hecht, A. (2007). Differential control of Wnt target genes involves epigenetic mechanisms and selective promoter occupancy by T-cell factors. Mol. Cell Biol. 27, 8164-8177
-
(2007)
Mol. Cell Biol.
, vol.27
, pp. 8164-8177
-
-
Wohrle, S.1
Wallmen, B.2
Hecht, A.3
-
27
-
-
84868149453
-
Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/β-catenin target gene expression
-
Wallmen, B., Schrempp, M., and Hecht, A. (2012). Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/β-catenin target gene expression. Nucleic Acids Res. 40, 9455-9469
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 9455-9469
-
-
Wallmen, B.1
Schrempp, M.2
Hecht, A.3
-
28
-
-
81355143310
-
Cell-context dependent TCF/LEF expression and function: Alternative tales of repression, de-repression and activation potentials
-
Mao, CD. and Byers, S.W. (2011). Cell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentials. Crit. Rev. Eukaryot. Gene Expr. 21, 207-236
-
(2011)
Crit. Rev. Eukaryot. Gene Expr
, vol.21
, pp. 207-236
-
-
Mao, C.D.1
Byers, S.W.2
-
29
-
-
0035033521
-
Beta-catenin-sensitive iso-forms of lymphoid enhancer factor-1 are selectively expressed in colon cancer
-
Hovanes, K, Li, T.W., Munguia, J.E., Truong, T., Milovanovic, T., Lawrence Marsh, J., Holcombe, R.F., and Waterman, M.L. (2001). Beta-catenin-sensitive iso-forms of lymphoid enhancer factor-1 are selectively expressed in colon cancer. Nat. Genet. 28, 53-57
-
(2001)
Nat. Genet.
, vol.28
, pp. 53-57
-
-
Hovanes, K.1
Li, T.W.2
Munguia, J.E.3
Truong, T.4
Milovanovic, T.5
Lawrence Marsh, J.6
Holcombe, R.F.7
Waterman, M.L.8
-
30
-
-
84870276846
-
The nuclear effector of wnt-signaling, tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas
-
Tiemessen, M.M., Baert, M.R., Schonewille, T., Brugman, M.H., Famili, F., Salvatori, D.C., Meijerink, J.P., Ozbek, U., Clevers, H., van Dongen, J.J. and Staal, F.J. (2012). The nuclear effector of wnt-signaling, tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas. PLoS Biol. 10, e1001430
-
(2012)
PLoS Biol.
, vol.10
, pp. e1001430
-
-
Tiemessen, M.M.1
Baert, M.R.2
Schonewille, T.3
Brugman, M.H.4
Famili, F.5
Salvatori, D.C.6
Meijerink, J.P.7
Ozbek, U.8
Clevers, H.9
Van Dongen, J.J.10
Staal, F.J.11
-
31
-
-
0034879853
-
The beta-catenin-TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival
-
Ioannidis, V., Beermann, F., Clevers, H., and Held, W. (2001). The beta-catenin-TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival. Nat. Immunol. 2, 691-697
-
(2001)
Nat. Immunol
, vol.2
, pp. 691-697
-
-
Ioannidis, V.1
Beermann, F.2
Clevers, H.3
Held, W.4
-
32
-
-
69449102426
-
Blocking beta-catenin binding to the ZBP1 promoter represses ZBP1 expression, leading to increased proliferation and migration of metastatic breast-cancer cells
-
Gu, W., Pan, F., and Singer, R.H. (2009). Blocking beta-catenin binding to the ZBP1 promoter represses ZBP1 expression, leading to increased proliferation and migration of metastatic breast-cancer cells. J. Cell Sci. 122, 1895-1905
-
(2009)
J. Cell Sci.
, vol.122
, pp. 1895-1905
-
-
Gu, W.1
Pan, F.2
Singer, R.H.3
-
33
-
-
78649318098
-
The wnt signaling pathway in cellular proliferation and differentiation: A tale of two coactivators
-
Teo, J.L. and Kahn, M. (2010). The Wnt signaling pathway in cellular proliferation and differentiation: a tale of two coactivators. Adv. Drug Deliv. Rev. 62, 1149-1155
-
(2010)
Adv. Drug Deliv. Rev.
, vol.62
, pp. 1149-1155
-
-
Teo, J.L.1
Kahn, M.2
-
34
-
-
24744470274
-
Specific inhibition of CBP/beta-catenin interaction rescues defects in neuronal differentiation caused by a presenilin-1 mutation
-
Teo, J.L., Ma, H., Nguyen, C, Lam, C, and Kahn, M. (2005). Specific inhibition of CBP/beta-catenin interaction rescues defects in neuronal differentiation caused by a presenilin-1 mutation. Proc. Natl. Acad. Sci. USA. 102, 12171-12176
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 12171-12176
-
-
Teo, J.L.1
Ma, H.2
Nguyen, C.3
Lam, C.4
Kahn, M.5
-
35
-
-
84964883522
-
P300/β-catenin interactions regulate adult progenitor cell differentiation downstream of Wnt5a/protein kinase C (PKC)
-
Rieger, M.E., Zhou, B., Solomon, N., Sunohara, M., Li, C, Nguyen, C, Liu, Y., Pan, J., Minoo, P., Crandall, E.D., Brody, S.L., Kahn, M., and Borok, Z. (2016). P300/β-catenin interactions regulate adult progenitor cell differentiation downstream of Wnt5a/protein kinase C (PKC). J. Biol. Chem. 12, 6569-6582
-
(2016)
J. Biol. Chem.
, vol.12
, pp. 6569-6582
-
-
Rieger, M.E.1
Zhou, B.2
Solomon, N.3
Sunohara, M.4
Li, C.5
Nguyen, C.6
Liu, Y.7
Pan, J.8
Minoo, P.9
Crandall, E.D.10
Brody, S.L.11
Kahn, M.12
Borok, Z.13
-
36
-
-
0033817339
-
β-catenin-histone deacetylase interactions regulate the transition of LEF1 from a transcriptional repressor to an activator
-
Billin, A.N., Thirlwell, H., and Ayer, D.E. (2000). β-Catenin-histone deacetylase interactions regulate the transition of LEF1 from a transcriptional repressor to an activator. Mol. Cell Biol. 20, 6882-6890
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 6882-6890
-
-
Billin, A.N.1
Thirlwell, H.2
Ayer, D.E.3
-
37
-
-
23144435753
-
Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing wnt and notch signaling pathways
-
Yamaguchi, M., Tonou-Fujimori, N, Komori, A., Maeda, R., Nojima, Y., Li, H., Okamoto, H., and Masai, I. (2005). Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways. Development 132, 3027-3043
-
(2005)
Development
, vol.132
, pp. 3027-3043
-
-
Yamaguchi, M.1
Tonou-Fujimori, N.2
Komori, A.3
Maeda, R.4
Nojima, Y.5
Li, H.6
Okamoto, H.7
Masai, I.8
-
38
-
-
84859882025
-
NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells
-
Ota, S., Ishitani, S., Shimizu, N, Matsumoto, K, Itoh, M., and Ishitani, T. (2012). NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells. EMBO J. 31, 1904-1915
-
(2012)
EMBO J.
, vol.31
, pp. 1904-1915
-
-
Ota, S.1
Ishitani, S.2
Shimizu, N.3
Matsumoto, K.4
Itoh, M.5
Ishitani, T.6
-
39
-
-
7744228427
-
Polycomb group proteins Ring1A/B link ubiqui-tylation of histone H2A to heritable gene silencing and X inactivation
-
de Napoles, M., Mermoud, J.E., Wakao, R., Tang, Y.A., Endoh, M., Appanah, R., Nesterova, T.B., Silva, J., Otte, A.P., Vidal, M., Koseki, H., and Brockdorff, N. (2004). Polycomb group proteins Ring1A/B link ubiqui-tylation of histone H2A to heritable gene silencing and X inactivation. Dev. Cell 7, 663-676
-
(2004)
Dev. Cell
, vol.7
, pp. 663-676
-
-
De Napoles, M.1
Mermoud, J.E.2
Wakao, R.3
Tang, Y.A.4
Endoh, M.5
Appanah, R.6
Nesterova, T.B.7
Silva, J.8
Otte, A.P.9
Vidal, M.10
Koseki, H.11
Brockdorff, N.12
-
40
-
-
55949124844
-
EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency
-
Shen, X., Liu, Y., Hsu, Y.J., Fujiwara, Y., Kim, J., Mao, X., Yuan, G.C., and Orkin, S.H. (2008). EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. Mol. Cell 32, 491-502
-
(2008)
Mol. Cell
, vol.32
, pp. 491-502
-
-
Shen, X.1
Liu, Y.2
Hsu, Y.J.3
Fujiwara, Y.4
Kim, J.5
Mao, X.6
Yuan, G.C.7
Orkin, S.H.8
-
41
-
-
3242889925
-
The Wnt/β-catenin pathway directs neuronal differentiation of cortical neural precursor cells
-
Hirabayashi, Y., Itoh, Y., Tabata, H., Nakajima, K, Akiyama, T., Masuyama, N, and Gotoh, Y. (2004). The Wnt/β-catenin pathway directs neuronal differentiation of cortical neural precursor cells. Development 131, 2791-2801
-
(2004)
Development
, vol.131
, pp. 2791-2801
-
-
Hirabayashi, Y.1
Itoh, Y.2
Tabata, H.3
Nakajima, K.4
Akiyama, T.5
Masuyama, N.6
Gotoh, Y.7
-
42
-
-
69949085080
-
Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition
-
Hirabayashi, Y., Suzki, N, Tsuboi, M., Endo, T.A., Toyoda, T., Shinga, J., Koseki, H, Vidal, M., and Gotoh, Y. (2009). Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition. Neuron 63, 600-613
-
(2009)
Neuron
, vol.63
, pp. 600-613
-
-
Hirabayashi, Y.1
Suzki, N.2
Tsuboi, M.3
Endo, T.A.4
Toyoda, T.5
Shinga, J.6
Koseki, H.7
Vidal, M.8
Gotoh, Y.9
-
43
-
-
2442715238
-
Cdx1 autoregulation is governed by a novel cdx1-LEF1 transcription complex
-
Beland, M., Pilon, N., Houle, M., Oh, K., Sylvestre, J.R., Prinos, P., and Lohnes, D. (2004). Cdx1 autoregulation is governed by a novel Cdx1-LEF1 transcription complex. Mol. Cell Biol. 24, 5028-5038
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 5028-5038
-
-
Beland, M.1
Pilon, N.2
Houle, M.3
Oh, K.4
Sylvestre, J.R.5
Prinos, P.6
Lohnes, D.7
-
44
-
-
84962079746
-
Sp5 and sp8 recruit beta-catenin and tcf1-lef1 to select enhancers to activate wnt target gene transcription
-
Kennedy, M.W., Chalamalasetty, R.B., Thomas, S., Garriock, R.J., Jailwala, P., and Yamaguchi, T.P. (2016). Sp5 and Sp8 recruit beta-catenin and Tcf1-Lef1 to select enhancers to activate wnt target gene transcription. Proc. Natl. Acad. Sci. USA. 113, 3545-3550
-
(2016)
Proc. Natl. Acad. Sci. USA
, vol.113
, pp. 3545-3550
-
-
Kennedy, M.W.1
Chalamalasetty, R.B.2
Thomas, S.3
Garriock, R.J.4
Jailwala, P.5
Yamaguchi, T.P.6
-
45
-
-
0034669131
-
Sp5, a new member of the sp1 family, is dynamically expressed during development and genetically interacts with brachyury
-
Harrison, S.M., Houzelstein, D., Dunwoodie, S.L., and Beddington, R.S. (2000). Sp5, a new member of the Sp1 family, is dynamically expressed during development and genetically interacts with Brachyury. Dev. Biol. 227, 358-372
-
(2000)
Dev. Biol.
, vol.227
, pp. 358-372
-
-
Harrison, S.M.1
Houzelstein, D.2
Dunwoodie, S.L.3
Beddington, R.S.4
-
46
-
-
0142123109
-
Sp8 is crucial for limb outgrowth and neuropore closure
-
Bell, S.M., Schreiner, C.M., Waclaw, R.R., Campbell, K, Potter, S.S., and Scott, W.J. (2003). Sp8 is crucial for limb outgrowth and neuropore closure. Proc. Natl. Acad. Sci. USA. 100, 12195-12200
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12195-12200
-
-
Bell, S.M.1
Schreiner, C.M.2
Waclaw, R.R.3
Campbell, K.4
Potter, S.S.5
Scott, W.J.6
-
47
-
-
84896596045
-
Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF
-
Schuijers, J., Mokry, M., Hatzis, P., Cuppen, E., and Clevers, H. (2014). Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF. EMBO J. 33, 146-156
-
(2014)
EMBO J.
, vol.33
, pp. 146-156
-
-
Schuijers, J.1
Mokry, M.2
Hatzis, P.3
Cuppen, E.4
Clevers, H.5
-
48
-
-
79551594937
-
β-catenin enhances oct-4 activity and reinforces pluripotency through a TCF-independent mechanism
-
Kelly, K.F., Ng, D.Y., Jayakumaran, G, Wood, G.A., Koide, H., and Doble, B.W. (2011). β-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism. Cell Stem Cell 8, 214-227
-
(2011)
Cell Stem Cell
, vol.8
, pp. 214-227
-
-
Kelly, K.F.1
Ng, D.Y.2
Jayakumaran, G.3
Wood, G.A.4
Koide, H.5
Doble, B.W.6
-
49
-
-
4043094754
-
Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes
-
Sinner, D., Rankin, S., Lee, M., and Zorn, A.M. (2004). Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes. Development 131, 3069-3080
-
(2004)
Development
, vol.131
, pp. 3069-3080
-
-
Sinner, D.1
Rankin, S.2
Lee, M.3
Zorn, A.M.4
-
50
-
-
18844382368
-
Functional interaction between beta-catenin and FOXO in oxidative stress signaling
-
Essers, M.A., de Vries-Smits, L.M., Barker, N., Polderman, P.E., Burgering, B.M., and Korswagen, H.C. (2005). Functional interaction between beta-catenin and FOXO in oxidative stress signaling. Science 308, 1181-1184
-
(2005)
Science
, vol.308
, pp. 1181-1184
-
-
Essers, M.A.1
De Vries-Smits, L.M.2
Barker, N.3
Polderman, P.E.4
Burgering, B.M.5
Korswagen, H.C.6
-
51
-
-
33947217823
-
Interaction between β-catenin and HIF-1 promotes cellular adaptation to hypoxia
-
Kaidi, A., Williams, A.C., and Paraskeva, C. (2007). Interaction between β-catenin and HIF-1 promotes cellular adaptation to hypoxia. Nat. Cell Biol. 9, 210-217
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 210-217
-
-
Kaidi, A.1
Williams, A.C.2
Paraskeva, C.3
-
52
-
-
75749152053
-
Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in wnt-dependent manner
-
Notani, D., Gottimukkala, K.P., Jayani, R.S., Limaye, A.S., Damle, M.V., Mehta, S., Purbey, P.K., Joseph, J., and Galande, S. (2010). Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner. PLoS Biol. 8, e1000296
-
(2010)
PLoS Biol.
, vol.8
, pp. e1000296
-
-
Notani, D.1
Gottimukkala, K.P.2
Jayani, R.S.3
Limaye, A.S.4
Damle, M.V.5
Mehta, S.6
Purbey, P.K.7
Joseph, J.8
Galande, S.9
-
53
-
-
84975138424
-
A positive regulatory loop between a wnt-regulated non-coding RNA and ASCL2 controls intestinal stem cell fate
-
Giakountis, A., Moulos, P., Zarkou, V., Oikonomou, C, Harokopos, V., Hatzigeorgiou, A.G, Reczko, M., and Hatzis, P. (2016). A positive regulatory loop between a Wnt-regulated non-coding RNA and ASCL2 controls intestinal stem cell fate. Cell Reports 15, 2588-2596
-
(2016)
Cell Reports
, vol.15
, pp. 2588-2596
-
-
Giakountis, A.1
Moulos, P.2
Zarkou, V.3
Oikonomou, C.4
Harokopos, V.5
Hatzigeorgiou, A.G.6
Reczko, M.7
Hatzis, P.8
-
55
-
-
0035554684
-
Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development
-
Gounari, F., Aifantis, I., Khazaie, K, Hoeflinger, S., Harada, N, Taketo, M.M., and von Boehmer, H. (2001). Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development. Nat. Immunol. 2, 863-869
-
(2001)
Nat. Immunol
, vol.2
, pp. 863-869
-
-
Gounari, F.1
Aifantis, I.2
Khazaie, K.3
Hoeflinger, S.4
Harada, N.5
Taketo, M.M.6
Von Boehmer, H.7
-
56
-
-
77957970301
-
Epigenetic modifications and human disease
-
Portela, A. and Esteller, M. (2010). Epigenetic modifications and human disease. Nat. Biotechnol. 28, 1057-1068
-
(2010)
Nat. Biotechnol
, vol.28
, pp. 1057-1068
-
-
Portela, A.1
Esteller, M.2
-
57
-
-
78651256572
-
The epigenetic regulator histone deacetylase 1 promotes transcription of a core neurogenic programme in zebrafish embryos
-
Harrison, M.R., Georgiou, A.S., Spaink, H.P., and Cunliffe, V.T. (2011). The epigenetic regulator Histone Deacetylase 1 promotes transcription of a core neurogenic programme in zebrafish embryos. BMC Genomics 12, 24
-
(2011)
BMC Genomics
, vol.12
, pp. 24
-
-
Harrison, M.R.1
Georgiou, A.S.2
Spaink, H.P.3
Cunliffe, V.T.4
-
58
-
-
0037023584
-
Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex
-
Kramps, T., Peter, O., Brunner, E., Nellen, D., Froesch, B., Chatterjee, S., Murone, M., Zullig, S., and Basler, K. (2002). Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. Cell 109, 47-60
-
(2002)
Cell
, vol.109
, pp. 47-60
-
-
Kramps, T.1
Peter, O.2
Brunner, E.3
Nellen, D.4
Froesch, B.5
Chatterjee, S.6
Murone, M.7
Zullig, S.8
Basler, K.9
-
59
-
-
66349126230
-
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
-
Gu, B., Sun, P., Yuan, Y., Moraes, R.C., Li, A., Teng, A., Agrawal, A., Rheaume, C, Bilanchone, V., Veltmaat, J.M., Takemaru, K, Millar, S., Lee, E.Y., Lewis, M.T., Li, B., and Dai, X. (2009). Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J. Cell Biol. 185, 811-826
-
(2009)
J. Cell Biol.
, vol.185
, pp. 811-826
-
-
Gu, B.1
Sun, P.2
Yuan, Y.3
Moraes, R.C.4
Li, A.5
Teng, A.6
Agrawal, A.7
Rheaume, C.8
Bilanchone, V.9
Veltmaat, J.M.10
Takemaru, K.11
Millar, S.12
Lee, E.Y.13
Lewis, M.T.14
Li, B.15
Dai, X.16
-
60
-
-
34247892478
-
Pygo1 and pygo2 roles in wnt signaling in Mammalian kidney development
-
Schwab, K.R., Patterson, L.T., Hartman, H.A., Song, N., Lang, R.A., Lin, X., and Potter, S.S. (2007). Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development. BMC Biol. 5, 15
-
(2007)
BMC Biol.
, vol.5
, pp. 15
-
-
Schwab, K.R.1
Patterson, L.T.2
Hartman, H.A.3
Song, N.4
Lang, R.A.5
Lin, X.6
Potter, S.S.7
-
61
-
-
84865249757
-
Dual functions of DP1 promote biphasic wnt-on and wnt-off states during anteroposterior neural patterning
-
Kim, W.T., Kim, H., Katanaev, V.L., Joon Lee, S., Ishitani, T., Cha, B., Han, J.K., and Jho, E.H. (2012). Dual functions of DP1 promote biphasic Wnt-on and Wnt-off states during anteroposterior neural patterning. EMBO J. 31, 3384-3397
-
(2012)
EMBO J.
, vol.31
, pp. 3384-3397
-
-
Kim, W.T.1
Kim, H.2
Katanaev, V.L.3
Joon Lee, S.4
Ishitani, T.5
Cha, B.6
Han, J.K.7
Jho, E.H.8
-
62
-
-
77957876629
-
Regulation of TCF3 by wnt-dependent phosphorylation during vertebrate axis specification
-
Hikasa, H., Ezan, J., Itoh, K, Li, X., Klymkowsky, M.W., and Sokol, S.Y. (2010). Regulation of TCF3 by Wnt-dependent phosphorylation during vertebrate axis specification. Dev. Cell 19, 521-532
-
(2010)
Dev. Cell
, vol.19
, pp. 521-532
-
-
Hikasa, H.1
Ezan, J.2
Itoh, K.3
Li, X.4
Klymkowsky, M.W.5
Sokol, S.Y.6
-
63
-
-
84922483614
-
Hipk2 and PP1c cooperate to maintain dvl protein levels required for wnt signal transduction
-
Shimizu, N., Ishitani, S., Sato, A., Shibuya, H., and Ishitani, T. (2014). Hipk2 and PP1c cooperate to maintain Dvl protein levels required for Wnt signal transduction. Cell Rep. 8, 1391-1404
-
(2014)
Cell Rep.
, vol.8
, pp. 1391-1404
-
-
Shimizu, N.1
Ishitani, S.2
Sato, A.3
Shibuya, H.4
Ishitani, T.5
-
64
-
-
33644828474
-
Nrarp functions to modulate neural-crest-cell differentiation by regulating LEF1 protein stability
-
Ishitani, T., Matsumoto, K, Chitnis, A.B., and Itoh, M. (2005). Nrarp functions to modulate neural-crest-cell differentiation by regulating LEF1 protein stability. Nat. Cell Biol. 7, 1106-1112
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 1106-1112
-
-
Ishitani, T.1
Matsumoto, K.2
Chitnis, A.B.3
Itoh, M.4
-
65
-
-
58249094059
-
Nrarp coordinates endothelial notch and wnt signaling to control vessel density in angiogenesis
-
Phng, L.K., Potente, M., Leslie, J.D., Babbage, J., Nyqvist, D., Lobov, I., Ondr, J.K., Rao, S., Lang, R.A., Thurston, G., and Gerhardt, H. (2009). Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis. Dev. Cell 16, 70-82
-
(2009)
Dev. Cell
, vol.16
, pp. 70-82
-
-
Phng, L.K.1
Potente, M.2
Leslie, J.D.3
Babbage, J.4
Nyqvist, D.5
Lobov, I.6
Ondr, J.K.7
Rao, S.8
Lang, R.A.9
Thurston, G.10
Gerhardt, H.11
-
69
-
-
70349695861
-
Tankyrase inhibition stabilizes axin and antagonizes wnt signalling
-
Huang, S.M., Mishina, Y.M., Liu, S., Cheung, A., Stegmeier, F., Michaud, G.A., Charlat, O., Wiellette, E., Zhang, Y., Wiessner, S., Hild, M., Shi, X., Wilson, C.J., Mickanin, C, Myer, V., Fazal, A., Tomlinson, R., Serluca, F., Shao, W., Cheng, H., Shultz, M., Rau, C, Schirle, M., Schlegl, J., Ghidelli, S., Fawell, S., Lu, C, Curtis, D., Kirschner, M.W., Lengauer, C, Finan, P.M., Tallarico, J.A., Bouwmeester, T., Porter, J.A., Bauer, A., and Cong, F. (2009). Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature 461, 614-620
-
(2009)
Nature
, vol.461
, pp. 614-620
-
-
Huang, S.M.1
Mishina, Y.M.2
Liu, S.3
Cheung, A.4
Stegmeier, F.5
Michaud, G.A.6
Charlat, O.7
Wiellette, E.8
Zhang, Y.9
Wiessner, S.10
Hild, M.11
Shi, X.12
Wilson, C.J.13
Mickanin, C.14
Myer, V.15
Fazal, A.16
Tomlinson, R.17
Serluca, F.18
Shao, W.19
Cheng, H.20
Shultz, M.21
Rau, C.22
Schirle, M.23
Schlegl, J.24
Ghidelli, S.25
Fawell, S.26
Lu, C.27
Curtis, D.28
Kirschner, M.W.29
Lengauer, C.30
Finan, P.M.31
Tallarico, J.A.32
Bouwmeester, T.33
Porter, J.A.34
Bauer, A.35
Cong, F.36
more..
-
70
-
-
58249122326
-
Small molecule-mediated disruption of wnt-dependent signaling in tissue regeneration and cancer
-
Chen, B., Dodge, M.E., Tang, W., Lu, J., Ma, Z., Fan, C.W., Wei, S., Hao, W., Kilgore, J., Williams, N.S., Roth, M.G, Amatruda, J.F., Chen, C, and Lum, L. (2009). Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nat. Chem. Biol. 5, 100-107
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 100-107
-
-
Chen, B.1
Dodge, M.E.2
Tang, W.3
Lu, J.4
Ma, Z.5
Fan, C.W.6
Wei, S.7
Hao, W.8
Kilgore, J.9
Williams, N.S.10
Roth, M.G.11
Amatruda, J.F.12
Chen, C.13
Lum, L.14
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