Specific inhibition of acyl-CoA oxidase-1 by an acetylenic acid improves hepatic lipid and Reactive Oxygen Species (ROS) metabolism in rats fed a high fat diet

Journal of Biological Chemistry

Volumn 292, Issue 9, 2017, Pages 3800-3809

  Zeng, Jia ^a   Deng, Senwen ^a   Wang, Yiping ^a   Li, Ping ^a   Tang, Lian ^a   Pang, Yefeng ^a  

^a HUNAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; FATTY ACIDS; METABOLISM; PHYSIOLOGY; RATS;

ACTIVATED PROTEINS; EFFECTIVE APPROACHES; FATTY ACID OXIDATION; MITOCHONDRIAL DYSFUNCTION; RATE-LIMITING ENZYMES; REACTIVE OXYGEN SPECIES; SERUM TRIGLYCERIDE; SPECIFIC INHIBITORS;

ENZYME INHIBITION;

10,12 TRICOSADIYNOIC ACID; ACETYLENIC ACID; ACYL COENZYME A OXIDASE; ACYL COENZYME A OXIDASE 1; FATTY ACID; HYDROGEN PEROXIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; REACTIVE OXYGEN METABOLITE; SIRTUIN 1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; 10,12-TRICOSADIYNOIC ACID; LIPID; OXYGEN; RECOMBINANT PROTEIN; SIRT1 PROTEIN, RAT; UNSATURATED FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FATTY ACID OXIDATION; INSULIN BLOOD LEVEL; LIPID DIET; LIPID METABOLISM; LIVER MITOCHONDRION; MALE; METABOLIC DISORDER; MITOCHONDRIAL RESPIRATION; NONHUMAN; OBESITY; PEROXISOME; RAT; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; LIVER; METABOLISM; MITOCHONDRION; WISTAR RAT;

ACYL-COA OXIDASE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BODY WEIGHT; DIET, HIGH-FAT; FATTY ACIDS, UNSATURATED; INSULIN; LIPIDS; LIVER; MALE; MITOCHONDRIA; OXYGEN; PEROXISOMES; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; SIRTUIN 1;

EID: 85014531474     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.763532     Document Type: Article

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