Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development

Developmental Cell

Volumn 40, Issue 4, 2017, Pages 331-341.e4

  Bulusu, Vinay ^a   Prior, Nicole ^a   Snaebjornsson, Marteinn T ^a   Kuehne, Andreas ^b   Sonnen, Katharina F ^a   Kress, Jana ^a   Stein, Frank ^a   Schultz, Carsten ^a   Sauer, Uwe ^b   Aulehla, Alexander ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b ETH ZURICH   (Switzerland)

Author keywords

aerobic glycolysis; mammalian embryonic development; metabolic gradients; metabolite sensor; presomitic mesoderm (PSM); real time imaging; somites; stable isotope tracing

Indexed keywords

GLUCOSE; PYRUVIC ACID; CARBON;

ANIMAL TISSUE; ARTICLE; EMBRYO; EMBRYO DEVELOPMENT; FLUORESCENCE RESONANCE ENERGY TRANSFER; GLYCOLYSIS; MESODERM; METABOLITE; MOUSE; NONHUMAN; PHENOTYPE; PRESOMITIC MESODERM; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPATIOTEMPORAL ANALYSIS; ANIMAL; ANTIBODY SPECIFICITY; BIOLOGICAL MODEL; CELL DIFFERENTIATION; COMPUTER SYSTEM; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENETICS; IN SITU HYBRIDIZATION; KINETICS; MAMMALIAN EMBRYO; METABOLIC FLUX ANALYSIS; METABOLISM; METABOLOMICS; REPORTER GENE; SOMITE;

ANIMALS; CARBON ISOTOPES; CELL DIFFERENTIATION; COMPUTER SYSTEMS; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; GLUCOSE; GLYCOLYSIS; IN SITU HYBRIDIZATION; KINETICS; MESODERM; METABOLIC FLUX ANALYSIS; METABOLOMICS; MICE; MODELS, BIOLOGICAL; ORGAN SPECIFICITY; PHENOTYPE; PYRUVIC ACID; SOMITES; SPATIO-TEMPORAL ANALYSIS;

EID: 85014121043     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2017.01.015     Document Type: Article

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