Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope

Nature Structural and Molecular Biology

Volumn 24, Issue 4, 2017, Pages 395-406

  Song, InYoung ^a   Gil, Anna ^a   Mishra, Rabinarayan ^a   Ghersi, Dario ^b   Selin, Liisa K ^a   Stern, Lawrence J ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA A2 ANTIGEN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; COMPLEMENTARITY DETERMINING REGION; EPITOPE; LYMPHOCYTE ANTIGEN RECEPTOR; PEPTIDE; PROTEIN BINDING;

ADULT; ALPHA HELIX; ANTIGEN RECOGNITION; ARTICLE; CD8+ T LYMPHOCYTE; CELL PLASTICITY; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; EX VIVO STUDY; HUMAN; HUMAN CELL; HYDROGEN BOND; MOLECULAR RECOGNITION; NEXT GENERATION SEQUENCING; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN MOTIF; SINGLE CELL ANALYSIS; STABLE EXPRESSION; UPREGULATION; YOUNG ADULT; AMINO ACID SEQUENCE; CHEMISTRY; COMPLEMENTARITY DETERMINING REGION; GENETICS; IMMUNOLOGY; JURKAT CELL LINE; MAJOR HISTOCOMPATIBILITY COMPLEX; METABOLISM; MOLECULAR MODEL; PROTEIN SECONDARY STRUCTURE; SIGNAL TRANSDUCTION; X RAY CRYSTALLOGRAPHY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CD8-POSITIVE T-LYMPHOCYTES; COMPLEMENTARITY DETERMINING REGIONS; CRYSTALLOGRAPHY, X-RAY; EPITOPES, T-LYMPHOCYTE; HLA-A2 ANTIGEN; HUMANS; IMMUNODOMINANT EPITOPES; JURKAT CELLS; MAJOR HISTOCOMPATIBILITY COMPLEX; MODELS, MOLECULAR; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION;

EID: 85014063434     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.3383     Document Type: Article

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