Structural basis for clonal diversity of the public T cell response to a dominant human cytomegalovirus epitope

Journal of Biological Chemistry

Volumn 290, Issue 48, 2015, Pages 29106-29119

  Yang, Xinbo ^a,b   Gao, Mingming ^a,b   Chen, Guobing ^c   Pierce, Brian G ^a   Lu, Jinghua ^d   Weng, Nan Ping ^c   Mariuzza, Roy A ^a,b  

^a UNIVERSITY OF MARYLAND   (United States)

^b Bldg 142   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; CELLS; CLONE CELLS; CYTOLOGY; EPITOPES; LYMPHOCYTES; PEPTIDES;

CLONAL DIVERSITIES; COMPLEMENTARITY-DETERMINING REGION 3; CYTOTOXIC T LYMPHOCYTES; HUMAN CYTOMEGALOVIRUS; MAJOR HISTOCOMPATIBILITY COMPLEX CLASS; STRUCTURAL BASIS; STRUCTURAL SOLUTIONS; T CELL RECEPTOR;

T-CELLS;

COMPLEMENT COMPONENT C3D; COMPLEMENT COMPONENT C7; COMPLEMENTARITY DETERMINING REGION 3ALPHA; COMPLEMENTARITY DETERMINING REGION 3BETA; COMPLEMENTARY DNA; EPITOPE; HLA A2 ANTIGEN; HLA E ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; LYMPHOCYTE ANTIGEN RECEPTOR;

ADULT; ALPHA HELIX; ANTIGEN BINDING; ARTICLE; BINDING SITE; CLONAL VARIATION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DISSOCIATION CONSTANT; EPITOPE MAPPING; ESCHERICHIA COLI; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; HUMAN EXPERIMENT; HYDROGEN BOND; IN VITRO STUDY; MALE; MOLECULAR DOCKING; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN MOTIF; SURFACE PLASMON RESONANCE; T LYMPHOCYTE; VIRUS MORPHOLOGY; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CLINICAL TRIAL; CYTOMEGALOVIRUS; GENETICS; IMMUNOLOGY; MIDDLE AGED;

ADULT; AMINO ACID MOTIFS; CD8-POSITIVE T-LYMPHOCYTES; CYTOMEGALOVIRUS; EPITOPES, T-LYMPHOCYTE; HLA-A2 ANTIGEN; HUMANS; IMMUNITY, CELLULAR; MIDDLE AGED; RECEPTORS, ANTIGEN, T-CELL;

EID: 84948663096     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.691311     Document Type: Article

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