Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity

Nature Communications

Volumn 8, Issue , 2017, Pages

  Yu, Yanqin ^a   Zuo, Xianbo ^b,c,d,e   He, Miao ^a   Gao, Jinping ^b,c,d,e   Fu, Yuchuan ^a   Qin, Chuanqi ^a   Meng, Liuyan ^a   Wang, Wenjun ^b,c,d,e   Song, Yaling ^a   Cheng, Yong ^a   Zhou, Fusheng ^b,c,d,e   Chen, Gang ^b,c,d,e   Zheng, Xiaodong ^b,c,d,e   Wang, Xinhuan ^a   Liang, Bo ^b,c,d,e   Zhu, Zhengwei ^b,c,d,e   Fu, Xiazhou ^a   Sheng, Yujun ^b,c,d,e   Hao, Jiebing ^f   Liu, Zhongyin ^g   Yan, Hansong ^h   Mangold, Elisabeth ⁱ   Ruczinski, Ingo ^j   Liu, Jianjun ^b,c,d,e   Marazita, Mary L ^k,l,m   Ludwig, Kerstin U ⁱ   Beaty, Terri H ⁿ   Zhang, Xuejun ^b,c,d,e,o   Sun, Liangdan ^b,c,d,e   Bian, Zhuan ^a   more..

^a WUHAN UNIVERSITY   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

^c MINISTRY OF SCIENCE AND TECHNOLOGY   (China)

^d BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^e Key Lab of Gene Resources Utilization for Severe Inherited Disorders   (China)

^f University of Henan Province   (China)

^g Stomatological Hospital of Nanyang   (China)

^h Stomatological Hospital of Xiangyang   (China)

ⁱ UNIVERSITY OF BONN   (Germany)

^j JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^k UNIVERSITY OF PITTSBURGH   (United States)

^l UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^m UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

ⁿ JOHNS HOPKINS UNIVERSITY   (United States)

^o FUDAN UNIVERSITY   (China)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR RECEPTOR 1; GENOMIC DNA; INTERFERON REGULATORY FACTOR 6; MATRIX METALLOPROTEINASE 16; MYC PROTEIN; PROTEIN PATCHED 1; TRANSCRIPTION FACTOR MAFB; TRANSCRIPTION FACTOR MSX1; WNT9B PROTEIN;

ABNORMALITY; ETIOLOGY; GENETIC ANALYSIS; GENOME; HERITABILITY; HETEROGENEITY; MORPHOLOGY; PHENOTYPE;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARHGAP29 GENE; ARTICLE; CASE CONTROL STUDY; CHINESE; COHORT ANALYSIS; CONTROLLED STUDY; DICER1 GENE; EMBRYO; ETHNIC DIFFERENCE; ETHNICITY; EUROPEAN; FAM49A GENE; FEMALE; FETUS; GADD45G GENE; GENE; GENE EXPRESSION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOME-WIDE ASSOCIATION STUDY; HERITABILITY; HUMAN; KRT18 GENE; LINC00640 GENE; LIP MALFORMATION; MAJOR CLINICAL STUDY; MALE; MOUSE; MULTIFACTORIAL GENETIC DISORDER; NOG GENE; NON SYNDROMIC CLEFT LIP WITH PALATE; NONHUMAN; NTN1 GENE; OFCC1 GENE; PALATE MALFORMATION; PHENOTYPE; RAD54B GENE; REPLICATION STUDY; RPS26 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SPRY1 GENE; SPRY2 GENE; TAF1B GENE; TMEM19 GENE; VAX1 GENE; AGE; ASIAN CONTINENTAL ANCESTRY GROUP; CLEFT LIP; CLEFT PALATE; ETHNOLOGY; GENETIC PREDISPOSITION; GENETICS; GENOTYPING TECHNIQUE; SEX FACTOR;

ADULT; AGE FACTORS; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CLEFT LIP; CLEFT PALATE; COHORT STUDIES; FEMALE; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPING TECHNIQUES; HUMANS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; SEX FACTORS;

EID: 85013747384     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms14364     Document Type: Article

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