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Volumn 45, Issue 5, 2016, Pages 1573-1587

Association of lactase persistence genotype with milk consumption, obesity and blood pressure: A Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis

Author keywords

Blood pressure; Body mass index; Lactase persistence; Mendelian randomization; Milk; Obesity

Indexed keywords

LACTASE; TRIPEPTIDE;

EID: 85013353284     PISSN: 03005771     EISSN: 14643685     Source Type: Journal    
DOI: 10.1093/ije/dyw074     Document Type: Article
Times cited : (36)

References (67)
  • 3
    • 0031750479 scopus 로고    scopus 로고
    • The genetically programmed down-regulation of lactase in children
    • Wang Y, Harvey CB, Hollox EJ, et al. The genetically programmed down-regulation of lactase in children. Gastroenterology 1998;114:123036.
    • (1998) Gastroenterology , vol.114 , pp. 123036
    • Wang, Y.1    Harvey, C.B.2    Hollox, E.J.3
  • 4
    • 34547398557 scopus 로고    scopus 로고
    • Correlation of intestinal disaccharidase activities with the C/T-13910 variant and age
    • Enattah NS, Kuokkanen M, Forsblom C et al. Correlation of intestinal disaccharidase activities with the C/T-13910 variant and age. World J Gastroenterol 2007; 13:350812.
    • (2007) World J Gastroenterol , vol.13 , pp. 350812
    • Enattah, N.S.1    Kuokkanen, M.2    Forsblom, C.3
  • 5
    • 0038476614 scopus 로고    scopus 로고
    • Transcriptional regulation of the lactase-phlorizin hydrolase gene by polymorphisms associated with adult-type hypolactasia
    • Kuokkanen M, Enattah NS, Oksanen A, Savilahti E, Orpana A, Jarvela I. Transcriptional regulation of the lactase-phlorizin hydrolase gene by polymorphisms associated with adult-type hypolactasia. Gut 2003;52:64752.
    • (2003) Gut , vol.52 , pp. 64752
    • Kuokkanen, M.1    Enattah, N.S.2    Oksanen, A.3    Savilahti, E.4    Orpana, A.5    Jarvela, I.6
  • 6
    • 85065760821 scopus 로고    scopus 로고
    • Transcriptional downregulation of the lactase (LCT) gene during childhood
    • Rasinpera H, Kuokkanen M, Kolho KL et al. Transcriptional downregulation of the lactase (LCT) gene during childhood. Gut 2005; 54:166061.
    • (2005) Gut , vol.54 , pp. 166061
    • Rasinpera, H.1    Kuokkanen, M.2    Kolho, K.L.3
  • 7
    • 0345059399 scopus 로고    scopus 로고
    • An upstream polymorphism associated with lactase persistence has increased enhancer activity
    • Troelsen JT, Olsen J, Moller J, Sjostrom H. An upstream polymorphism associated with lactase persistence has increased enhancer activity. Gastroenterology 2003;125:1686_94.
    • (2003) Gastroenterology , vol.125
    • Troelsen, J.T.1    Olsen, J.2    Moller, J.3    Sjostrom, H.4
  • 8
    • 0141702274 scopus 로고    scopus 로고
    • Lactase persistence DNA variant enhances lactase promoter activity in vitro: Functional role as a cis regulatory element
    • Olds LC, Sibley E. Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory element. Hum Mol Genet 2003;12:23340.
    • (2003) Hum Mol Genet , vol.12 , pp. 23340
    • Olds, L.C.1    Sibley, E.2
  • 9
    • 29644439954 scopus 로고    scopus 로고
    • T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro
    • Lewinsky RH, Jensen TG, Moller J, Stensballe A, Olsen J, Troelsen JT. T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro. Hum Mol Genet 2005;14:394553.
    • (2005) Hum Mol Genet , vol.14 , pp. 394553
    • Lewinsky, R.H.1    Jensen, T.G.2    Moller, J.3    Stensballe, A.4    Olsen, J.5    Troelsen, J.T.6
  • 10
    • 84867025727 scopus 로고    scopus 로고
    • Several different lactase persistence associated alleles and high diversity of the lactase gene in the admixed Brazilian population
    • Friedrich DC, Santos SE, Ribeiro-dos-Santos AK, Hutz MH. Several different lactase persistence associated alleles and high diversity of the lactase gene in the admixed Brazilian population. PLoS One 2012;7(9)e46520.
    • (2012) PLoS One , vol.7 , Issue.9
    • Friedrich, D.C.1    Santos, S.E.2    Ribeiro-Dos-Santos, A.K.3    Hutz, M.H.4
  • 11
    • 1542320651 scopus 로고    scopus 로고
    • Diet, nutrition and the prevention of osteoporosis
    • Prentice A. Diet, nutrition and the prevention of osteoporosis. Public Health Nutr 2004;7:22743.
    • (2004) Public Health Nutr , vol.7 , pp. 22743
    • Prentice, A.1
  • 12
    • 1942436221 scopus 로고    scopus 로고
    • Mendelian randomization: Prospects, potentials and limitations
    • Davey Smith D, Ebrahim S. Mendelian randomization: prospects, potentials and limitations. Int J Epidemiol 2004;33:3042.
    • (2004) Int J Epidemiol , vol.33 , pp. 3042
    • Davey Smith, D.1    Ebrahim, S.2
  • 13
    • 58149173403 scopus 로고    scopus 로고
    • Adult-type hypolactasia is not a predisposing factor for the early functional and structural changes of atherosclerosis: The cardiovascular risk in young finns study
    • Lehtimaki T, Hutri-Kahonen N, Kahonen M et al. Adult-type hypolactasia is not a predisposing factor for the early functional and structural changes of atherosclerosis: the Cardiovascular Risk in Young Finns Study. Clin Sci (Lond) 2008;115:26571.
    • (2008) Clin Sci (Lond) , vol.115 , pp. 26571
    • Lehtimaki, T.1    Hutri-Kahonen, N.2    Kahonen, M.3
  • 15
    • 1942475329 scopus 로고    scopus 로고
    • Genetic predisposition for adult lactose intolerance and relation to diet, bone density, and bone fractures
    • Obermayer-Pietsch BM, Bonelli CM, Walter DE et al. Genetic predisposition for adult lactose intolerance and relation to diet, bone density, and bone fractures. J Bone Miner Res 2004;19:4247.
    • (2004) J Bone Miner Res , vol.19 , pp. 4247
    • Obermayer-Pietsch, B.M.1    Bonelli, C.M.2    Walter, D.E.3
  • 16
    • 30444446380 scopus 로고    scopus 로고
    • Molecularly-defined lactose malabsorption, milk consumption and anthropometric differences in adult males
    • Gugatschka M, Dobnig H, Fahrleitner-Pammer A et al. Molecularly-defined lactose malabsorption, milk consumption and anthropometric differences in adult males. QJM 2005;98:85763.
    • (2005) QJM , vol.98 , pp. 85763
    • Gugatschka, M.1    Dobnig, H.2    Fahrleitner-Pammer, A.3
  • 17
    • 33845497182 scopus 로고    scopus 로고
    • Lactase non-persistence and milk consumption in Estonia
    • Lember M, Torniainen S, Kull M et al. Lactase non-persistence and milk consumption in Estonia. World J Gastroenterol 2006;12:732931.
    • (2006) World J Gastroenterol , vol.12 , pp. 732931
    • Lember, M.1    Torniainen, S.2    Kull, M.3
  • 18
    • 33847663738 scopus 로고    scopus 로고
    • Adult-type hypolactasia and calcium availability: Decreased calcium intake or impaired calcium absorption?
    • Obermayer-Pietsch BM, Gugatschka M, Reitter S et al. Adult-type hypolactasia and calcium availability: decreased calcium intake or impaired calcium absorption?. Osteoporos Int 2007;18:44551.
    • (2007) Osteoporos Int , vol.18 , pp. 44551
    • Obermayer-Pietsch, B.M.1    Gugatschka, M.2    Reitter, S.3
  • 19
    • 60749124969 scopus 로고    scopus 로고
    • Lactase persistence-related genetic variant: Population substructure and health outcomes
    • Davey Smith G, Lawlor DA, Timpson NJ et al. Lactase persistence-related genetic variant: population substructure and health outcomes. Eur J Hum Genet 2009;17:35767.
    • (2009) Eur J Hum Genet , vol.17 , pp. 35767
    • Davey Smith, G.1    Lawlor, D.A.2    Timpson, N.J.3
  • 20
    • 77952484063 scopus 로고    scopus 로고
    • Mendelian randomization as applied to coronary heart disease, including recent advances incorporating new technology
    • Lewis SJ. Mendelian randomization as applied to coronary heart disease, including recent advances incorporating new technology. Circ Cardiovasc Genet 2010;3:10917.
    • (2010) Circ Cardiovasc Genet , vol.3 , pp. 10917
    • Lewis, S.J.1
  • 21
    • 84871036375 scopus 로고    scopus 로고
    • Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010
    • Lozano R, Naghavi M, Foreman K et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380:2095_128.
    • (2012) Lancet , vol.380
    • Lozano, R.1    Naghavi, M.2    Foreman, K.3
  • 22
    • 0034612618 scopus 로고    scopus 로고
    • Primary prevention of coronary heart disease in women through diet and lifestyle
    • Stampfer MJ, Hu FB, Manson JE, Rimm EB, Willett WC. Primary prevention of coronary heart disease in women through diet and lifestyle. N Engl J Med 2000;343:16–22.
    • (2000) N Engl J Med , vol.343 , pp. 16-22
    • Stampfer, M.J.1    Hu, F.B.2    Manson, J.E.3    Rimm, E.B.4    Willett, W.C.5
  • 23
    • 83555163843 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of elevated blood pressure and consumption of dairy foods
    • Ralston RA, Lee JH, Truby H, Palermo CE, Walker KZ. A systematic review and meta-analysis of elevated blood pressure and consumption of dairy foods. J Hum Hypertens 2012;26:313.
    • (2012) J Hum Hypertens , vol.26 , pp. 313
    • Ralston, R.A.1    Lee, J.H.2    Truby, H.3    Palermo, C.E.4    Walker, K.Z.5
  • 24
    • 84868194719 scopus 로고    scopus 로고
    • Dairy consumption and incidence of hypertension: A dose-response meta-analysis of prospective cohort studies
    • Soedamah-Muthu SS, Verberne LD, Ding EL, Engberink MF, Geleijnse JM. Dairy consumption and incidence of hypertension: a dose-response meta-analysis of prospective cohort studies. Hypertension 2012;60:113137.
    • (2012) Hypertension , vol.60 , pp. 113137
    • Soedamah-Muthu, S.S.1    Verberne, L.D.2    Ding, E.L.3    Engberink, M.F.4    Geleijnse, J.M.5
  • 25
    • 50549086234 scopus 로고    scopus 로고
    • Effect of milk tripeptides on blood pressure: A meta-analysis of randomized controlled trials
    • Xu JY, Qin LQ, Wang PY, Li W, Chang C. Effect of milk tripeptides on blood pressure: a meta-analysis of randomized controlled trials. Nutrition 2008;24:93340.
    • (2008) Nutrition , vol.24 , pp. 93340
    • Xu, J.Y.1    Qin, L.Q.2    Wang, P.Y.3    Li, W.4    Chang, C.5
  • 26
    • 84876557415 scopus 로고    scopus 로고
    • Do the lactotri-peptides isoleucine-proline-proline and valine-proline-proline reduce systolic blood pressure in European subjects? A meta-analysis of randomized controlled trials
    • Cicero AF, Aubin F, Azais-Braesco V, Borghi C. Do the lactotri-peptides isoleucine-proline-proline and valine-proline-proline reduce systolic blood pressure in European subjects? A meta-analysis of randomized controlled trials. Am J Hypertens 2013;26:442–49.
    • (2013) Am J Hypertens , vol.26 , pp. 442-449
    • Cicero, A.F.1    Aubin, F.2    Azais-Braesco, V.3    Borghi, C.4
  • 27
    • 77953555973 scopus 로고    scopus 로고
    • Dairy and milk consumption and child growth: Is BMI involved? An analysis of NHANES 1999-2004
    • Wiley AS. Dairy and milk consumption and child growth: Is BMI involved? An analysis of NHANES 1999-2004. Am J Hum Biol 2010;22:51725.
    • (2010) Am J Hum Biol , vol.22 , pp. 51725
    • Wiley, A.S.1
  • 28
    • 84928189123 scopus 로고    scopus 로고
    • Milk intake, height and body mass index in preschool children
    • DeBoer MD, Agard HE, Scharf RJ. Milk intake, height and body mass index in preschool children. Arch Dis Child 2015;100:46065.
    • (2015) Arch Dis Child , vol.100 , pp. 46065
    • DeBoer, M.D.1    Agard, H.E.2    Scharf, R.J.3
  • 29
    • 84899646664 scopus 로고    scopus 로고
    • Dairy consumption and pre-school, school-age and adolescent obesity in developed countries: A systematic review and meta-analysis
    • Dror DK. Dairy consumption and pre-school, school-age and adolescent obesity in developed countries: a systematic review and meta-analysis. Obes Rev 2014;15:516_27.
    • (2014) Obes Rev , vol.15
    • Dror, D.K.1
  • 30
    • 84936798400 scopus 로고    scopus 로고
    • Milk intake is not associated with low risk of diabetes or overweight-obesity: A Mendelian randomization study in 97,811 Danish individuals
    • Bergholdt HK, Nordestgaard BG, Ellervik C. Milk intake is not associated with low risk of diabetes or overweight-obesity: a Mendelian randomization study in 97,811 Danish individuals. Am J Clin Nutr 2015;102:48796.
    • (2015) Am J Clin Nutr , vol.102 , pp. 48796
    • Bergholdt, H.K.1    Nordestgaard, B.G.2    Ellervik, C.3
  • 31
    • 77956630099 scopus 로고    scopus 로고
    • Impact of water intake on energy intake and weight status: A systematic review
    • Daniels MC, Popkin BM. Impact of water intake on energy intake and weight status: a systematic review. Nutr Rev 2010;68:50521.
    • (2010) Nutr Rev , vol.68 , pp. 50521
    • Daniels, M.C.1    Popkin, B.M.2
  • 32
    • 84885675113 scopus 로고    scopus 로고
    • Changes in water and beverage intake and long-term weight changes: Results from three prospective cohort studies
    • Pan A, Malik VS, Hao T, Willett WC, Mozaffarian D, Hu FB. Changes in water and beverage intake and long-term weight changes: results from three prospective cohort studies. Int J Obes (Lond) 2013;37:137885.
    • (2013) Int J Obes (Lond) , vol.37 , pp. 137885
    • Pan, A.1    Malik, V.S.2    Hao, T.3    Willett, W.C.4    Mozaffarian, D.5    Hu, F.B.6
  • 33
    • 0037322022 scopus 로고    scopus 로고
    • ‘Mendelian randomization’: Can genetic epidemiology contribute to understanding environmental determinants of disease?
    • Davey Smith G, Ebrahim S. ‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease? Int J Epidemiol 2003;32:122.
    • (2003) Int J Epidemiol , vol.32 , pp. 122
    • Davey Smith, G.1    Ebrahim, S.2
  • 34
    • 38049023073 scopus 로고    scopus 로고
    • Clustered environments and randomized genes: A fundamental distinction between conventional and genetic epidemiology
    • Davey Smith G, Lawlor DA, Harbord R, Timpson N, Day I, Ebrahim S. Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology. PLoS Med 2007;4:e352.
    • (2007) PLoS Med , vol.4
    • Davey Smith, G.1    Lawlor, D.A.2    Harbord, R.3    Timpson, N.4    Day, I.5    Ebrahim, S.6
  • 35
    • 84906838227 scopus 로고    scopus 로고
    • Mendelian randomization: Genetic anchors for causal inference in epidemiological studies
    • Davey Smith G, Hemani G. Mendelian randomization: genetic anchors for causal inference in epidemiological studies. Hum Mol Genet 2014;23:R8998.
    • (2014) Hum Mol Genet , vol.23 , pp. R8998
    • Davey Smith, G.1    Hemani, G.2
  • 36
    • 77950663235 scopus 로고    scopus 로고
    • European lactase persistence genotype shows evidence of association with increase in body mass index
    • Kettunen J, Silander K, Saarela O et al. European lactase persistence genotype shows evidence of association with increase in body mass index. Hum Mol Genet 2010;19:112936.
    • (2010) Hum Mol Genet , vol.19 , pp. 112936
    • Kettunen, J.1    Silander, K.2    Saarela, O.3
  • 37
    • 84936757019 scopus 로고    scopus 로고
    • Milk intake is not associated with ischaemic heart disease in observational or Mendelian randomization analyses in 98,529 Danish adults
    • Bergholdt HK, Nordestgaard BG, Varbo A, Ellervik C. Milk intake is not associated with ischaemic heart disease in observational or Mendelian randomization analyses in 98,529 Danish adults. Int J Epidemiol 2015;44:587603.
    • (2015) Int J Epidemiol , vol.44 , pp. 587603
    • Bergholdt, H.K.1    Nordestgaard, B.G.2    Varbo, A.3    Ellervik, C.4
  • 38
    • 33645819803 scopus 로고    scopus 로고
    • Cohort profile: The 1982 Pelotas (Brazil) birth cohort study
    • Victora CG, Barros FC. Cohort Profile: The 1982 Pelotas (Brazil) birth cohort study. Int J Epidemiol 2006;35: 23742.
    • (2006) Int J Epidemiol , vol.35 , pp. 23742
    • Victora, C.G.1    Barros, F.C.2
  • 39
    • 84936741531 scopus 로고    scopus 로고
    • Cohort profile update: The 1982 Pelotas (Brazil) birth cohort study
    • Horta BL, Gigante DP, Goncalves H et al. Cohort Profile Update: The 1982 Pelotas (Brazil) Birth Cohort Study. Int J Epidemiol 2015;44:441.
    • (2015) Int J Epidemiol , vol.44 , pp. 441
    • Horta, B.L.1    Gigante, D.P.2    Goncalves, H.3
  • 40
    • 26944439004 scopus 로고    scopus 로고
    • A nationwide wealth score based on the 2000 Brazilian demographic census
    • Barros AJ, Victora CG. [A nationwide wealth score based on the 2000 Brazilian demographic census.] Rev Saude Publica 2005;39:52329.
    • (2005) Rev Saude Publica , vol.39 , pp. 52329
    • Barros, A.J.1    Victora, C.G.2
  • 41
    • 69749099417 scopus 로고    scopus 로고
    • Fast model-based estimation of ancestry in unrelated individuals
    • Alexander DH, Novembre J, Lange K. Fast model-based estimation of ancestry in unrelated individuals. Genome Res 2009;19:165564.
    • (2009) Genome Res , vol.19 , pp. 165564
    • Alexander, D.H.1    Novembre, J.2    Lange, K.3
  • 42
    • 84991503771 scopus 로고    scopus 로고
    • Genomic ancestry and ethnoracial self-classification based on 5,871 community-dwelling Brazilians (The Epigen Initiative)
    • Lima-Costa MF, Rodrigues LC, Barreto ML et al. Genomic ancestry and ethnoracial self-classification based on 5,871 community-dwelling Brazilians (The Epigen Initiative). Sci Rep 2015;5:9812.
    • (2015) Sci Rep , vol.5 , pp. 9812
    • Lima-Costa, M.F.1    Rodrigues, L.C.2    Barreto, M.L.3
  • 43
    • 84883488876 scopus 로고    scopus 로고
    • Associations of the lactase persistence allele and lactose intake with body composition among multiethnic children
    • Malek AJ, Klimentidis YC, Kell KP, Fernandez JR. Associations of the lactase persistence allele and lactose intake with body composition among multiethnic children. Genes Nutr 2013;8:48794.
    • (2013) Genes Nutr , vol.8 , pp. 48794
    • Malek, A.J.1    Klimentidis, Y.C.2    Kell, K.P.3    Fernandez, J.R.4
  • 44
    • 84914700351 scopus 로고    scopus 로고
    • The lactase persistence genotype is a protective factor for the metabolic syndrome
    • Friedrich DC, de Andrade FM, Fiegenbaum M et al. The lactase persistence genotype is a protective factor for the metabolic syndrome. Genet Mol Biol 2014;37:61115.
    • (2014) Genet Mol Biol , vol.37 , pp. 61115
    • Friedrich, D.C.1    De Andrade, F.M.2    Fiegenbaum, M.3
  • 45
    • 84863621055 scopus 로고    scopus 로고
    • Lactase persistence and milk consumption are associated with body height in Swedish preadolescents and adolescents
    • Epub 2011 Sep 6
    • Almon R, Nilsson TK, Sjostrom M, Engfeldt P. Lactase persistence and milk consumption are associated with body height in Swedish preadolescents and adolescents. Food Nutr Res 2011; 55. doi: 10.3402/fnr.v55i0.7253. [Epub 2011 Sep 6.]
    • (2011) Food Nutr Res , vol.55
    • Almon, R.1    Nilsson, T.K.2    Sjostrom, M.3    Engfeldt, P.4
  • 46
    • 84906217992 scopus 로고    scopus 로고
    • An association between lactose intolerance and anthropometric variables in the Sudanese Shagia tribe (East Africa)
    • Kempinska-Podhorodecka A, Knap O, Popadowska A, Drozd A. An association between lactose intolerance and anthropometric variables in the Sudanese Shagia tribe (East Africa). Ann Hum Biol 2014;41:46064.
    • (2014) Ann Hum Biol , vol.41 , pp. 46064
    • Kempinska-Podhorodecka, A.1    Knap, O.2    Popadowska, A.3    Drozd, A.4
  • 47
    • 84883140899 scopus 로고    scopus 로고
    • The lactase persistence genotype is associated with body mass index and dairy consumption in the D.E.S.I.R. Study
    • Lamri A, Poli A, Emery N, Bellili N et al. The lactase persistence genotype is associated with body mass index and dairy consumption in the D.E.S.I.R. study. Metabolism 2013;62:132329.
    • (2013) Metabolism , vol.62 , pp. 132329
    • Lamri, A.1    Poli, A.2    Emery, N.3    Bellili, N.4
  • 48
    • 84875275313 scopus 로고    scopus 로고
    • The lactase persistence - 13910C . T polymorphism shows indication of association with abdominal obesity among Portuguese children
    • Albuquerque D, Nobrega C, Manco L. The lactase persistence - 13910C . T polymorphism shows indication of association with abdominal obesity among Portuguese children. Acta Paediatr 2013;102:e15357.
    • (2013) Acta Paediatr , vol.102
    • Albuquerque, D.1    Nobrega, C.2    Manco, L.3
  • 50
    • 84866601832 scopus 로고    scopus 로고
    • Association of the European lactase persistence variant (LCT-13910 C . T polymorphism) with obesity in the Canary Islands
    • Almon R, Alvarez-Leon EE, Serra-Majem L. Association of the European lactase persistence variant (LCT-13910 C . T polymorphism) with obesity in the Canary Islands. PLoS One 2012;7:e43978.
    • (2012) PLoS One , vol.7
    • Almon, R.1    Alvarez-Leon, E.E.2    Serra-Majem, L.3
  • 51
    • 79960836838 scopus 로고    scopus 로고
    • Association of the LCT-13910C . T polymorphism with obesity and its modulation by dairy products in a Mediterranean population
    • Corella D, Arregui M, Coltell O et al. Association of the LCT-13910C . T polymorphism with obesity and its modulation by dairy products in a Mediterranean population. Obesity (Silver Spring) 2011;19:170714.
    • (2011) Obesity (Silver Spring) , vol.19 , pp. 170714
    • Corella, D.1    Arregui, M.2    Coltell, O.3
  • 52
    • 4644310840 scopus 로고    scopus 로고
    • The genetic variant of lactase persistence C (13910) T as a risk factor for type I and II diabetes in the Finnish population
    • Enattah NS, Forsblom C, Rasinpera H, Tuomi T, Groop PH, Jarvela I. The genetic variant of lactase persistence C (13910) T as a risk factor for type I and II diabetes in the Finnish population. Eur J Clin Nutr 2004;58:131922.
    • (2004) Eur J Clin Nutr , vol.58 , pp. 131922
    • Enattah, N.S.1    Forsblom, C.2    Rasinpera, H.3    Tuomi, T.4    Groop, P.H.5    Jarvela, I.6
  • 53
    • 77950864600 scopus 로고    scopus 로고
    • Associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the Canary Islands
    • Almon R, Alvarez-Leon EE, Engfeldt P, Serra-Majem L, Magnuson A, Nilsson TK. Associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the Canary Islands. Eur J Nutr 2010;49:14146.
    • (2010) Eur J Nutr , vol.49 , pp. 14146
    • Almon, R.1    Alvarez-Leon, E.E.2    Engfeldt, P.3    Serra-Majem, L.4    Magnuson, A.5    Nilsson, T.K.6
  • 54
    • 67649855154 scopus 로고    scopus 로고
    • Does greater adiposity increase blood pressure and hypertension risk?: Mendelian randomization using the FTO/MC4R genotype
    • Timpson NJ, Harbord R, Davey Smith G, Zacho J, Tybjaerg-Hansen A, Nordestgaard BG. Does greater adiposity increase blood pressure and hypertension risk?: Mendelian randomization using the FTO/MC4R genotype. Hypertension 2009;54:8490.
    • (2009) Hypertension , vol.54 , pp. 8490
    • Timpson, N.J.1    Harbord, R.2    Davey Smith, G.3    Zacho, J.4    Tybjaerg-Hansen, A.5    Nordestgaard, B.G.6
  • 55
    • 84893735878 scopus 로고    scopus 로고
    • Causal effects of body mass index on cardiometabolic traits and events: A Mendelian randomization analysis
    • Holmes MV, Lange LA, Palmer T et al. Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis. Am J Hum Genet 2014;94:198–208.
    • (2014) Am J Hum Genet , vol.94 , pp. 198-208
    • Holmes, M.V.1    Lange, L.A.2    Palmer, T.3
  • 56
    • 84884642795 scopus 로고    scopus 로고
    • Effect of probiotic fermented milk on blood pressure: A meta-analysis of randomised controlled trials
    • Dong JY, Szeto IM, Makinen K et al. Effect of probiotic fermented milk on blood pressure: a meta-analysis of randomised controlled trials. Br J Nutr 2013;110:1188–94.
    • (2013) Br J Nutr , vol.110 , pp. 1188-1194
    • Dong, J.Y.1    Szeto, I.M.2    Makinen, K.3
  • 57
    • 84898969507 scopus 로고    scopus 로고
    • How sound is the science behind the dietary recommendations for dairy?
    • Weaver CM. How sound is the science behind the dietary recommendations for dairy?. Am J Clin Nutr 2014;99(Suppl 5)1217–22S.
    • (2014) Am J Clin Nutr , vol.99
    • Weaver, C.M.1
  • 58
    • 53549109724 scopus 로고    scopus 로고
    • Milk feeding and dietary patterns predict weight and fat gains in infancy
    • Baird J, Poole J, Robinson S et al. Milk feeding and dietary patterns predict weight and fat gains in infancy. Paediatr Perinat Epidemiol 2008;22:575–86.
    • (2008) Paediatr Perinat Epidemiol , vol.22 , pp. 575-586
    • Baird, J.1    Poole, J.2    Robinson, S.3
  • 59
    • 84908609006 scopus 로고    scopus 로고
    • Association between eating patterns and body mass index in a sample of children and adolescents in Northeastern Brazil
    • Santos NH, Fiaccone RL, Barreto ML, Silva LA, Silva R de C. Association between eating patterns and body mass index in a sample of children and adolescents in Northeastern Brazil. Cad Saude Publica 2014;30:2235–45.
    • (2014) Cad Saude Publica , vol.30 , pp. 2235-2245
    • Santos, N.H.1    Fiaccone, R.L.2    Barreto, M.L.3    Silva, L.A.4    Silva, R.5
  • 60
    • 84936891941 scopus 로고    scopus 로고
    • Dietary patterns and their associations with childhood obesity in China
    • Zhang J, Wang H, Wang Y et al. Dietary patterns and their associations with childhood obesity in China. Br J Nutr 2015;113:1978–84.
    • (2015) Br J Nutr , vol.113 , pp. 1978-1984
    • Zhang, J.1    Wang, H.2    Wang, Y.3
  • 61
    • 79952624880 scopus 로고    scopus 로고
    • Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health
    • Davey Smith G. Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health. Genes Nutr 2011;6:27–43.
    • (2011) Genes Nutr , vol.6 , pp. 27-43
    • Davey Smith, G.1
  • 62
    • 0038334174 scopus 로고    scopus 로고
    • Quantifying biases in causal models: Classical confounding vs collider-stratification bias
    • Greenland S. Quantifying biases in causal models: classical confounding vs collider-stratification bias. Epidemiology 2003;14:300–06.
    • (2003) Epidemiology , vol.14 , pp. 300-306
    • Greenland, S.1
  • 63
    • 23044468633 scopus 로고    scopus 로고
    • Demonstrating stratification in a European American population
    • Campbell CD, Ogburn EL, Lunetta KL et al. Demonstrating stratification in a European American population. Nat Genet 2005;37:868–72.
    • (2005) Nat Genet , vol.37 , pp. 868-872
    • Campbell, C.D.1    Ogburn, E.L.2    Lunetta, K.L.3
  • 64
    • 79958172224 scopus 로고    scopus 로고
    • Chronic noncommunicable diseases in Brazil: Burden and current challenges
    • Schmidt MI, Duncan BB, Azevedo e Silva G et al. Chronic noncommunicable diseases in Brazil: burden and current challenges. Lancet 2011;377:1949–61.
    • (2011) Lancet , vol.377 , pp. 1949-1961
    • Schmidt, M.I.1    Duncan, B.B.2    Azevedo e Silva, G.3
  • 65
    • 33846343947 scopus 로고    scopus 로고
    • A novel polymorphism associated with lactose tolerance in Africa: Multiple causes for lactase persistence?
    • Ingram CJ, Elamin MF, Mulcare CA et al. A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence? Hum Genet 2007;120:779–88.
    • (2007) Hum Genet , vol.120 , pp. 779-788
    • Ingram, C.J.1    Elamin, M.F.2    Mulcare, C.A.3
  • 66
    • 80054849075 scopus 로고    scopus 로고
    • The -14010*C variant associated with lactase persistence is located between an Oct-1 and HNF1alpha binding site and increases lactase promoter activity
    • Jensen TG, Liebert A, Lewinsky R, Swallow DM, Olsen J, Troelsen JT. The -14010*C variant associated with lactase persistence is located between an Oct-1 and HNF1alpha binding site and increases lactase promoter activity. Hum Genet 2011;130:483–93.
    • (2011) Hum Genet , vol.130 , pp. 483-493
    • Jensen, T.G.1    Liebert, A.2    Lewinsky, R.3    Swallow, D.M.4    Olsen, J.5    Troelsen, J.T.6
  • 67
    • 79951895658 scopus 로고    scopus 로고
    • The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected
    • Pena SD, Di Pietro G, Fuchshuber-Moraes M et al. The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected. PLoS One 2011;6:e17063.
    • (2011) PLoS One , vol.6
    • Pena, S.D.1    Di Pietro, G.2    Fuchshuber-Moraes, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.