Associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the Canary Islands

European Journal of Nutrition

Volumn 49, Issue 3, 2010, Pages 141-146

  Almon, Ricardo ^a   Álvarez Leon, Eva E ^b,c   Engfeldt, Peter ^a   Serra Majem, Lluís ^b,c   Magnuson, Anders ^d   Nilsson, Torbjörn K ^d  

^a ÖREBRO UNIVERSITY   (Sweden)

^b UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

^c HOSPITAL UNIVERSITARIO INSULAR DE GRAN CANARIA   (Spain)

^d ÖREBRO UNIVERSITY HOSPITAL   (Sweden)

Author keywords

LCT 13910 C>T polymorphism; Mendelian randomization; Metabolic syndrome; Milk; Nutrigenetics

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LACTASE;

ADULT; AGED; ARTICLE; BLOOD PRESSURE; CALORIC INTAKE; CARDIOVASCULAR RISK; EDUCATION; FEMALE; FOOD INTAKE; GENOTYPE; GLUCOSE BLOOD LEVEL; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HYPERTRIGLYCERIDEMIA; LACTOSE INTOLERANCE; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; MILK; PHENOTYPE; PHYSICAL ACTIVITY; PREVALENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SPAIN;

ADOLESCENT; ADULT; AGED; ANIMALS; BIOLOGICAL MARKERS; CROSS-SECTIONAL STUDIES; DIET; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LACTASE; LACTOSE INTOLERANCE; MALE; METABOLIC SYNDROME X; MIDDLE AGED; MILK; NUTRITION SURVEYS; ODDS RATIO; POLYMORPHISM, GENETIC; SEX DISTRIBUTION; SPAIN; YOUNG ADULT;

EID: 77950864600     PISSN: 14366207     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00394-009-0058-2     Document Type: Article

References (44)

1. CA Adebamowo D Spiegelman CS Berkey FW Danby HH Rockett GA Colditz WC Willett MD Holmes 2008 Milk consumption and acne in teenaged boys J Am Acad Dermatol 58 794 795 10.1016/j.jaad.2007.08.049
2. KG Alberti P Zimmet J Shaw 2006 Metabolic syndrome-a new world-wide definition. A consensus statement from the International Diabetes Federation Diabet Med 23 469 480 10.1111/j.1464-5491.2006.01858.x 1:STN:280: DC%2BD283lslGgsQ%3D%3D
3. R Almon P Engfeldt C Tysk M Sjostrom TK Nilsson 2007 Prevalence and trends in adult-type hypolactasia in different age cohorts in Central Sweden diagnosed by genotyping for the adult-type hypolactasia-linked LCT -13910C>T mutation Scand J Gastroenterol 42 165 170 10.1080/00365520600825257 1:CAS:528:DC%2BD2sXjtF2jsb0%3D (Pubitemid 46253858)
4. EE Alvarez Leon L Ribas Barba L Serra Majem 2003 Prevalence of the metabolic syndrome in the population of Canary Islands, Spain Med Clin (Barc) 120 172 174 10.1157/13043145 (Pubitemid 36266971)
5. EE Alvarez-Leon B Roman-Vinas L Serra-Majem 2006 Dairy products and health: a review of the epidemiological evidence Br J Nutr 96 Suppl 1 S94 99 1:CAS:528:DC%2BD28XpvVCqsbk%3D
6. Aranceta J (2005) La leche y los lácteos en la alimentación de los españoles. In: Arancenta J, Serra-Majem L (eds) Leche, lácteos y salud. Médica-Panamericana, Madrid, pp 31-41
7. CS Berkey GA Colditz HR Rockett AL Frazier WC Willett 2009 Dairy consumption and female height growth: prospective cohort study Cancer Epidemiol Biomarkers Prev 18 1881 1887 10.1158/1055-9965.EPI-08-1163 1:CAS:528: DC%2BD1MXmvF2js7k%3D
8. CS Berkey HR Rockett WC Willett GA Colditz 2005 Milk, dairy fat, dietary calcium, and weight gain: a longitudinal study of adolescents Arch Pediatr Adolesc Med 159 543 550 10.1001/archpedi.159.6.543 (Pubitemid 40973476)
9. K Brismar SE Nilsson 2009 Interrelations and associations of serum levels of steroids and pituitary hormones with markers of insulin resistance, inflammatory activity, and renal function in men and women aged >70 years in an 8-year longitudinal study of opposite-sex twins Gend Med 6 Suppl 1 123 136 10.1016/j.genm.2009.01.001
10. MA Cornier D Dabelea TL Hernandez RC Lindstrom AJ Steig NR Stob RE Van Pelt H Wang RH Eckel 2008 The metabolic syndrome Endocr Rev 29 777 822 10.1210/er.2008-0024 1:CAS:528:DC%2BD1MXmt1yjtg%3D%3D
11. M Denise Robertson 2007 Metabolic cross talk between the colon and the periphery: implications for insulin sensitivity Proc Nutr Soc 66 351 361 10.1017/S0029665107005617 1:STN:280:DC%2BD2svhvFGhug%3D%3D (Pubitemid 47076232)
12. EL Ding Y Song VS Malik S Liu 2006 Sex differences of endogenous sex hormones and risk of type 2 diabetes: a systematic review and meta-analysis JAMA 295 1288 1299 10.1001/jama.295.11.1288 1:CAS:528:DC%2BD28Xis1ShsLs%3D
13. PC Elwood JE Pickering AM Fehily 2007 Milk and dairy consumption, diabetes and the metabolic syndrome: the Caerphilly prospective study J Epidemiol Community Health 61 695 698 10.1136/jech.2006.053157 (Pubitemid 47122068)
14. NS Enattah A Trudeau V Pimenoff L Maiuri S Auricchio L Greco M Rossi M Lentze JK Seo S Rahgozar I Khalil M Alifrangis S Natah L Groop N Shaat A Kozlov G Verschubskaya D Comas K Bulayeva SQ Mehdi JD Terwilliger T Sahi E Savilahti M Perola A Sajantila I Jarvela L Peltonen 2007 Evidence of still-ongoing convergence evolution of the lactase persistence T-13910 alleles in humans Am J Hum Genet 81 615 625 10.1086/520705 1:CAS:528:DC%2BD2sXhtVSqurvI (Pubitemid 47330220)
15. S Erlingsson S Herard O Dahlqvist Leinhard T Lindstrom T Lanne M Borga FH Nystrom 2009 Men develop more intraabdominal obesity and signs of the metabolic syndrome after hyperalimentation than women Metabolism 58 995 1001 10.1016/j.metabol.2009.02.028 1:CAS:528:DC%2BD1MXntVKltrk%3D
16. RJ FitzGerald BA Murray DJ Walsh 2004 Hypotensive peptides from milk proteins J Nutr 134 980S 988S 1:CAS:528:DC%2BD2cXjtFOrs7c%3D
17. ES Ford 2005 Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidence Diabetes Care 28 1769 1778 10.2337/diacare.28.7.1769 (Pubitemid 40923091)
18. D Ganmaa A Sato 2005 The possible role of female sex hormones in milk from pregnant cows in the development of breast, ovarian and corpus uteri cancers Med Hypotheses 65 1028 1037 10.1016/j.mehy.2005.06.026 1:CAS:528:DC%2BD2MXhtVOksL7N (Pubitemid 41430335)
19. D Ganmaa PY Wang LQ Qin K Hoshi A Sato 2001 Is milk responsible for male reproductive disorders? Med Hypotheses 57 510 514 10.1054/mehy.2001.1380 1:STN:280:DC%2BD3Mrls1SktA%3D%3D (Pubitemid 33052047)
20. E Giovannucci M Pollak Y Liu EA Platz N Majeed EB Rimm WC Willett 2003 Nutritional predictors of insulin-like growth factor I and their relationships to cancer in men Cancer Epidemiol Biomarkers Prev 12 84 89 1:CAS:528: DC%2BD3sXhtVOks74%3D (Pubitemid 36193996)
21. P Henriquez Sanchez C Diaz Romero E Rodriguez Rodriguez F Lopez Blanco E Alvarez Leon J Diaz Cremades MC Pastor Ferrer L Serra Majem 2000 Biochemical assessment of nutritional status in the Canary Islands population (1998) Arch Latinoam Nutr 50 43 54 1:STN:280:DC%2BD3M3nsVSnsA%3D%3D
22. A Hjartaker A Lagiou N Slimani E Lund MD Chirlaque E Vasilopoulou X Zavitsanos F Berrino C Sacerdote MC Ocke PH Peeters D Engeset G Skeie A Aller P Amiano G Berglund S Nilsson A McTaggart EA Spencer K Overvad A Tjonneland F Clavel-Chapelon J Linseisen M Schulz B Hemon E Riboli 2002 Consumption of dairy products in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort: data from 35,955 24-h dietary recalls in 10 European countries Public Health Nutr 5 1259 1271 10.1079/PHN2002403 1:STN:280: DC%2BD3s7is1Ogsg%3D%3D (Pubitemid 36313617)
23. C Hoppe C Molgaard A Juul KF Michaelsen 2004 High intakes of skimmed milk, but not meat, increase serum IGF-I and IGFBP-3 in eight-year-old boys Eur J Clin Nutr 58 1211 1216 10.1038/sj.ejcn.1601948 1:CAS:528:DC%2BD2cXmvFGisro%3D (Pubitemid 39264017)
24. CJ Ingram MF Elamin CA Mulcare ME Weale A Tarekegn TO Raga E Bekele FM Elamin MG Thomas N Bradman DM Swallow 2007 A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence? Hum Genet 120 779 788 10.1007/s00439-006-0291-1 1:CAS:528:DC%2BD2sXnsF2hsg%3D%3D (Pubitemid 46128833)
25. T Joy P Lahiry RL Pollex RA Hegele 2008 Genetics of metabolic syndrome Curr Diab Rep 8 141 148 10.1007/s11892-008-0025-y 1:CAS:528:DC%2BD1cXms1Wgt78%3D
26. AJ Lanou ND Barnard 2008 Dairy and weight loss hypothesis: an evaluation of the clinical trials Nutr Rev 66 272 279 10.1111/j.1753-4887.2008.00032.x (Pubitemid 351623970)
27. DA Lawlor S Ebrahim N Timpson G Davey Smith 2005 Avoiding milk is associated with a reduced risk of insulin resistance and the metabolic syndrome: findings from the British Women's Heart and Health Study Diabet Med 22 808 811 10.1111/j.1464-5491.2005.01537.x 1:STN:280:DC%2BD2M3mvVKltA%3D%3D (Pubitemid 40805906)
28. J Levesque B Lamarche 2008 The metabolic syndrome: definitions, prevalence and management J Nutrigenet Nutrigenomics 1 100 108 10.1159/000112457 (Pubitemid 351301321)
29. C Livingstone M Collison 2002 Sex steroids and insulin resistance Clin Sci (Lond) 102 151 166 10.1042/CS20010197 1:CAS:528:DC%2BD38Xit1Wrur4%3D (Pubitemid 34185043)
30. TK Nilsson CA Johansson 2004 A novel method for diagnosis of adult hypolactasia by genotyping of the -13910 C/T polymorphism with Pyrosequencing technology Scand J Gastroenterol 39 287 290 10.1080/00365520310008304 1:STN:280:DC%2BD2c7nvFKrsg%3D%3D (Pubitemid 38388876)
31. H Nishizawa I Shimomura K Kishida N Maeda H Kuriyama H Nagaretani M Matsuda H Kondo N Furuyama S Kihara T Nakamura Y Tochino T Funahashi Y Matsuzawa 2002 Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein Diabetes 51 2734 2741 10.2337/diabetes.51.9.2734 1:CAS:528:DC%2BD38Xmslerur0%3D (Pubitemid 34970926)
32. EM Ostman HG Liljeberg Elmstahl IM Bjorck 2001 Inconsistency between glycemic and insulinemic responses to regular and fermented milk products Am J Clin Nutr 74 96 100 1:CAS:528:DC%2BD3MXltVWrs78%3D
33. M Pfeuffer J Schrezenmeir 2007 Milk and the metabolic syndrome Obes Rev 8 109 118 10.1111/j.1467-789X.2006.00265.x 1:CAS:528:DC%2BD2sXkt12nsbg%3D (Pubitemid 46239439)
34. SN Rajpathak EB Rimm B Rosner WC Willett FB Hu 2006 Calcium and dairy intakes in relation to long-term weight gain in US men Am J Clin Nutr 83 559 566 1:CAS:528:DC%2BD28XislSku7Y%3D (Pubitemid 44699200)
35. V Regitz-Zagrosek E Lehmkuhl S Mahmoodzadeh 2007 Gender aspects of the role of the metabolic syndrome as a risk factor for cardiovascular disease Gend Med 4 Suppl B S162 177 10.1016/S1550-8579(07)80056-8
36. T Sahi 1994 Genetics and epidemiology of adult-type hypolactasia Scand J Gastroenterol Suppl 202 7 20 10.3109/00365529409091740 1:STN:280: DyaK2czhs12rsg%3D%3D (Pubitemid 24128390)
37. L Serra Majem A Cabrera Leon A Sierra Lopez 2000 Conclusions of the Canary Islands Nutrition Survey (1997-1998). Foundations for a nutrition policy in Canary Islands Arch Latinoam Nutr 50 62 70 1:STN:280:DC%2BD3M3nsVSntg%3D%3D
38. L Serra Majem L Ribas Barba A Armas Navarro E Alvarez Leon A Sierra 2000 Energy and nutrient intake and risk of inadequate intakes in Canary Islands (1997-1998) Arch Latinoam Nutr 50 7 22 1:STN:280:DC%2BD3M3nsVSntw%3D%3D (Pubitemid 33295736)
39. Serra-Majem L, Aranceta J (2002) Alimentación infantil y juvenil. Masson S.A., Barcelona
40. FL Suarez D Savaiano P Arbisi MD Levitt 1997 Tolerance to the daily ingestion of two cups of milk by individuals claiming lactose intolerance Am J Clin Nutr 65 1502 1506 1:CAS:528:DyaK2sXivFWntL4%3D (Pubitemid 27187764)
41. DM Swallow 2003 Genetics of lactase persistence and lactose intolerance Annu Rev Genet 37 197 219 10.1146/annurev.genet.37.110801.143820 1:CAS:528:DC%2BD2cXhsFGluw%3D%3D (Pubitemid 38041425)
42. SA Tishkoff FA Reed A Ranciaro BF Voight CC Babbitt JS Silverman K Powell HM Mortensen JB Hirbo M Osman M Ibrahim SA Omar G Lema TB Nyambo J Ghori S Bumpstead JK Pritchard GA Wray P Deloukas 2007 Convergent adaptation of human lactase persistence in Africa and Europe Nat Genet 39 31 40 10.1038/ng1946 1:CAS:528:DC%2BD28XhtlGktLjK (Pubitemid 46026499)
43. AS Wiley 2005 Does milk make children grow? Relationships between milk consumption and height in NHANES 1999-2002 Am J Hum Biol 17 425 441 10.1002/ajhb.20411 (Pubitemid 41150530)
44. MB Zemel 2003 Role of dietary calcium and dairy products in modulating adiposity Lipids 38 139 146 10.1007/s11745-003-1044-6 1:CAS:528: DC%2BD3sXjtFGhurg%3D (Pubitemid 36457722)