The 214010*C variant associated with lactase persistence is located between an Oct-1 and HNF1α binding site and increases lactase promoter activity

Human Genetics

Volumn 130, Issue 4, 2011, Pages 483-493

  Jensen, Tine G K ^a   Liebert, Anke ^b   Lewinsky, Rikke ^a   Swallow, Dallas M ^b   Olsen, Jørgen ^a   Troelsen, Jesper T ^a,c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c ROSKILDE UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; GUANINE; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; LACTASE; OCTAMER TRANSCRIPTION FACTOR 1; PRIMER DNA; TRANSCRIPTION FACTOR;

ALLELE; ARTICLE; BINDING SITE; ENHANCER REGION; GENE CONTROL; GENETIC VARIABILITY; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM; ADULT; CELL STRAIN CACO 2; CHEMISTRY; DNA FOOTPRINTING; GEL MOBILITY SHIFT ASSAY; GENETIC POLYMORPHISM; GENETICS; LACTOSE INTOLERANCE; METABOLISM;

ADULT; ALLELES; BINDING SITES; CACO-2 CELLS; DNA FOOTPRINTING; DNA PRIMERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENHANCER ELEMENTS, GENETIC; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HUMANS; LACTASE; LACTOSE INTOLERANCE; OCTAMER TRANSCRIPTION FACTOR-1; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; TRANSCRIPTION FACTORS;

EID: 80054849075     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-011-0966-0     Document Type: Article

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