Measures of metabolism and complexity in the brain of patients with disorders of consciousness

NeuroImage: Clinical

Volumn 14, Issue , 2017, Pages 354-362

  Bodart, Olivier ^a   Gosseries, Olivia ^a,b   Wannez, Sarah ^a   Thibaut, Aurore ^a   Annen, Jitka ^a   Boly, Melanie ^a,b   Rosanova, Mario ^c,f   Casali, Adenauer G ^c,d   Casarotto, Silvia ^c   Tononi, Giulio ^b   Massimini, Marcello ^c,e   Laureys, Steven ^a  

^a University and University Hospital of Liège   (Belgium)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c UNIVERSITY OF MILAN   (Italy)

^d FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^e IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

^f Fondazione Europea di Ricerca Biomedica   (Italy)

Author keywords

Brain injury; Disorders of consciousness; Electroencephalography; Positron emission tomography; Transcranial magnetic stimulation; Unresponsive wakefulness syndrome minimally conscious state

Indexed keywords

FLUORODEOXYGLUCOSE F 18; OXYGEN;

ACQUIRED BRAIN INJURY; ADULT; ANTERIOR CINGULATE; ARTICLE; AUDITORY EVOKED POTENTIAL; BRAIN METABOLISM; CLINICAL ARTICLE; CONSCIOUSNESS; CONSCIOUSNESS DISORDER; CONTROLLED STUDY; FEMALE; HUMAN; MALE; METABOLIC RATE; MIDDLE AGED; MINIMALLY CONSCIOUS STATE; POSITRON EMISSION TOMOGRAPHY; PRECUNEUS; PRIORITY JOURNAL; SIGNAL NOISE RATIO; TRAUMATIC BRAIN INJURY; UNCONSCIOUSNESS; WAKEFULNESS; WHITE NOISE; YOUNG ADULT; BLOOD; BRAIN; BRAIN INJURY; COMPLICATION; CONSCIOUSNESS DISORDERS; DIAGNOSTIC IMAGING; ELECTROENCEPHALOGRAPHY; IMAGE PROCESSING; METABOLISM; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; TRANSCRANIAL MAGNETIC STIMULATION;

ADULT; BRAIN; BRAIN INJURIES; CONSCIOUSNESS DISORDERS; ELECTROENCEPHALOGRAPHY; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OXYGEN; POSITRON-EMISSION TOMOGRAPHY; TRANSCRANIAL MAGNETIC STIMULATION; YOUNG ADULT;

EID: 85013213406     PISSN: None     EISSN: 22131582     Source Type: Journal    
DOI: 10.1016/j.nicl.2017.02.002     Document Type: Article

References (36)

1. Bardin, J.C., Fins, J.J., Katz, D.I., Hersh, J., Heier, L.A., Tabelow, K., Dyke, J.P., Ballon, D., Schiff, N.D., Voss, H.U., Dissociations between behavioural and functional magnetic resonance imaging-based evaluations of cognitive function after brain injury. Brain 134 (2011), 769–782, 10.1093/brain/awr005.
2. Bardin, J.C., Schiff, N.D., Voss, H.U., Pattern classification of volitional functional magnetic resonance imaging responses in patients with severe brain injury. Arch. Neurol. 69 (2012), 176–181, 10.1001/archneurol.2011.892.
3. Bodart, O., Laureys, S., Gosseries, O., Coma and disorders of consciousness: scientific advances and practical considerations for clinicians. Semin. Neurol. 33 (2013), 83–90, 10.1055/s-0033-1348965.
4. Casali, A.G., Gosseries, O., Rosanova, M., Boly, M., Sarasso, S., Casali, K.R., Casarotto, S., Bruno, M.-A., Laureys, S., Tononi, G., Massimini, M., A theoretically based index of consciousness independent of sensory processing and behavior. Sci. Transl. Med. 5 (2013), 1–10, 10.1126/scitranslmed.3006294.
5. Casarotto, S., Romero Lauro, L.J., Bellina, V., Casali, A.G., Rosanova, M., Pigorini, A., Defendi, S., Mariotti, M., Massimini, M., EEG responses to TMS are sensitive to changes in the perturbation parameters and repeatable over time. PLoS One, 5, 2010, e10281, 10.1371/journal.pone.0010281.
6. Casarotto, S., Comanducci, A., Rosanova, M., Sarasso, S., Fecchio, M., Napolitani, M., Pigorini, A., Casali, A.G., Trimarchi, P., Boly, M., Gosseries, O., Bodart, O., Curto, F., Landi, C., Mariotti, M., Devalle, G., Laureys, S., Tononi, G., Massimini, M., Stratification of unresponsive patients by an independantly validated index of brain complexity. Ann. Neurol., 2016, 10.1002/ana.24779.
7. Cruse, D., Chennu, S., Chatelle, C., Bekinschtein, T.A., Fernandez-Espejo, D., Pickard, J.D., Laureys, S., Owen, A.M., Bedside detection of awareness in the vegetative state: a cohort study. Lancet 378 (2011), 2088–2094, 10.1016/S0140-6736(11)61224-5.
8. Ferrarelli, F., Massimini, M., Sarasso, S., Casali, A.G., Riedner, B.A., Angelini, G., Tononi, G., Pearce, R.A., Breakdown in cortical effective connectivity during midazolam-induced loss of consciousness. Proc. Natl. Acad. Sci. U. S. A. 107 (2010), 2681–2686, 10.1073/pnas.0913008107.
9. Gantner, I.S., Bodart, O., Laureys, S., Demertzi, A., Our rapidly changing understanding of acute and chronic disorders of consciousness: challenges for neurologists. Future Neurol. 8 (2012), 43–54, 10.2217/fnl.12.77.
10. Giacino, J.T., Ashwal, S., Childs, N., Cranford, R., Jennett, B., Katz, D.I., Kelly, J.P., Rosenberg, J.H., Whyte, J., Zafonte, R.D., Zasler, N.D., The minimally conscious state: definition and diagnostic criteria. Neurology 58 (2002), 349–353.
11. Giacino, J.T., Kalmar, K., Whyte, J., The JFK coma recovery scale-revised: measurement characteristics and diagnostic utility. Arch. Phys. Med. Rehabil. 85 (2004), 2020–2029.
12. Giacino, J.T., Whyte, J., Bagiella, E., Kalmar, K., Childs, N., Khademi, A., Eifert, B., Long, D., Katz, D.I., Cho, S., Yablon, S.A., Luther, M., Hammond, F.M., Nordenbo, A., Novak, P., Mercer, W., Maurer-Karattup, P., Sherer, M., Placebo-controlled trial of amantadine for severe traumatic brain injury. N. Engl. J. Med. 366 (2012), 819–826, 10.1056/NEJMoa1102609.
13. Giacino, J.T., Fins, J.J., Laureys, S., Schiff, N.D., Disorders of consciousness after acquired brain injury: the state of the science. Nat. Rev. Neurol. 10 (2014), 99–114, 10.1038/nrneurol.2013.279.
14. Goldfine, A.M., Victor, J.D., Conte, M.M., Bardin, J.C., Schiff, N.D., Determination of awareness in patients with severe brain injury using EEG power spectral analysis. Clin. Neurophysiol. 122 (2011), 2157–2168, 10.1016/j.clinph.2011.03.022.
15. Gosseries, O., Zasler, N.D., Laureys, S., Recent advances in disorders of consciousness: focus on the diagnosis. Brain Inj. 28 (2014), 1141–1150, 10.3109/02699052.2014.920522.
16. Gosseries, O., Sarasso, S., Casarotto, S., Boly, M., Schnakers, C., Napolitani, M., Bruno, M.-A., Ledoux, D., Tshibanda, J.F., Massimini, M., Laureys, S., Rosanova, M., On the cerebral origin of EEG responses to TMS: insights from severe cortical lesions. Brain Stimul. 8 (2015), 142–149, 10.1016/j.brs.2014.10.008.
17. Ilmoniemi, R.J., Virtanen, J., Ruohonen, J., Karhu, J., Aronen, H.J., Naatanen, R., Katila, T., Neuronal responses to magnetic stimulation reveal cortical reactivity and connectivity. Neuroreport 8 (1997), 3537–3540.
18. Laureys, S., Goldman, S., Phillips, C., Van Bogaert, P., Aerts, J., Luxen, A., Franck, G., Maquet, P., Impaired effective cortical connectivity in vegetative state: preliminary investigation using PET. NeuroImage 9 (1999), 377–382, 10.1006/nimg.1998.0414.
19. Laureys, S., Owen, A.M., Schiff, N.D., Brain function in coma, vegetative state, and related disorders. Lancet Neurol. 3 (2004), 537–546, 10.1016/S1474-4422(04)00852-X.
20. Massimini, M., Ferrarelli, F., Huber, R., Esser, S.K., Singh, H., Tononi, G., Breakdown of cortical effective connectivity during sleep. Science (80-) 309 (2005), 2228–2232, 10.1126/science.1117256.
21. Massimini, M., Boly, M., Casali, A.G., Rosanova, M., Tononi, G., A perturbational approach for evaluating the brain's capacity for consciousness. Prog. Brain Res. 177 (2009), 201–214, 10.1016/S0079-6123(09)17714-2.
22. Massimini, M., Ferrarelli, F., Murphy, M., Huber, R., Riedner, B., Casarotto, S., Tononi, G., Cortical reactivity and effective connectivity during REM sleep in humans. Cogn. Neurosci. 1 (2010), 176–183, 10.1080/17588921003731578.
23. Massimini, M., Ferrarelli, F., Sarasso, S., Tononi, G., Cortical mechanisms of loss of consciousness: insight from TMS/EEG studies. Arch. Ital. Biol. 150 (2012), 44–55, 10.4449/aib.v150i2.1361.
24. Monti, M.M., Vanhaudenhuyse, A., Coleman, M.R., Boly, M., Pickard, J.D., Tshibanda, L., Owen, A.M., Laureys, S., Willful modulation of brain activity in disorders of consciousness. N. Engl. J. Med. 362 (2010), 579–589, 10.1056/NEJMoa0905370.
25. Nakayama, N., Okumura, A., Shinoda, J., Nakashima, T., Iwama, T., Relationship between regional cerebral metabolism and consciousness disturbance in traumatic diffuse brain injury without large focal lesions: an FDG-PET study with statistical parametric mapping analysis. J. Neurol. Neurosurg. Psychiatry 77 (2006), 856–862, 10.1136/jnnp.2005.080523.
26. Owen, A.M., Coleman, M.R., Boly, M., Davis, M.H., Laureys, S., Pickard, J.D., Detecting awareness in the vegetative state. Science (80–), 313, 2006, 1402, 10.1126/science.1130197.
27. Rosanova, M., Gosseries, O., Casarotto, S., Boly, M., Casali, A.G., Bruno, M.-A., Mariotti, M., Boveroux, P., Tononi, G., Laureys, S., Massimini, M., Recovery of cortical effective connectivity and recovery of consciousness in vegetative patients. Brain 135 (2012), 1308–1320, 10.1093/brain/awr340.
28. Sarasso, S., Boly, M., Napolitani, M., Gosseries, O., Charland-verville, V., Casarotto, S., Rosanova, M., Casali, A.G., Brichant, J.-F., Boveroux, P., Rex, S., Tononi, G., Laureys, S., Massimini, M., Consciousness and complexity during unresponsiveness induced by propofol, xenon, and ketamine. Curr. Biol. 25 (2015), 1–7, 10.1016/j.cub.2015.10.014.
29. Schiff, N.D., Fins, J.J., Brain death and disorders of consciousness. Curr. Biol. 26 (2016), R572–R576, 10.1016/j.cub.2016.02.027.
30. Schiff, N.D., Giacino, J.T., Kalmar, K., Victor, J.D., Baker, K., Gerber, M., Fritz, B., Eisenberg, B., Biondi, T., O'Connor, J., Kobylarz, E.J., Farris, S., Machado, A., McCagg, C., Plum, F., Fins, J.J., Rezai, A.R., Behavioural improvements with thalamic stimulation after severe traumatic brain injury. Nature 448 (2007), 600–603, 10.1038/nature06041.
31. Seel, R.T., Sherer, M., Whyte, J., Katz, D.I., Giacino, J.T., Rosenbaum, A.M., Hammond, F.M., Kalmar, K., Pape, T.L., Zafonte, R.D., Biester, R.C., Kaelin, D., Kean, J., Zasler, N.D., Assessment scales for disorders of consciousness: evidence-based recommendations for clinical practice and research. Arch. Phys. Med. Rehabil. 91 (2010), 1795–1813, 10.1016/j.apmr.2010.07.218.
32. Stender, J., Gosseries, O., Bruno, M.-A., Charland-Verville, V., Vanhaudenhuyse, A., Demertzi, A., Chatelle, C., Thonnard, M., Thibaut, A., Heine, L., Soddu, A., Boly, M., Schnakers, C., Gjedde, A., Laureys, S., Diagnostic precision of PET imaging and functional MRI in disorders of consciousness: a clinical validation study. Lancet 6736 (2014), 8–16, 10.1016/S0140-6736(14)60042-8.
33. Stender, J., Mortensen, K.N.N., Thibaut, A., Darkner, S., Laureys, S., Gjedde, A., Kupers, R., The minimal energetic requirement of sustained awareness after brain injury. Curr. Biol. 26 (2016), 1494–1499, 10.1016/j.cub.2016.04.024.
34. Thibaut, A., Bruno, M.-A., Chatelle, C., Gosseries, O., Vanhaudenhuyse, A., Demertzi, A., Schnakers, C., Thonnard, M., Charland-Verville, V., Bernard, C., Bahri, M., Phillips, C., Boly, M., Hustinx, R., Laureys, S., Metabolic activity in external and internal awareness networks in severely brain-damaged patients. J. Rehabil. Med. 44 (2012), 487–494, 10.2340/16501977-0940.
35. Thibaut, A., Bruno, M.-A., Ledoux, D., Demertzi, A., Laureys, S., tDCS in patients with disorders of consciousness. Neurology 82 (2014), 1–7, 10.1212/WNL.0000000000000260.
36. Whyte, J., Myers, R., Incidence of clinically significant responses to zolpidem among patients with disorders of consciousness: a preliminary placebo controlled trial. Am. J. Phys. Med. Rehabil. 88 (2009), 410–418, 10.1097/PHM.0b013e3181a0e3a0.