메뉴 건너뛰기




Volumn 4, Issue JUN, 2016, Pages

Border security: The role of RIPK3 in epithelium homeostasis

Author keywords

Cancer; DSS; IL 1 ; IL 23; Inflammasome; Necroptosis; RIPK1; Tissue repair

Indexed keywords


EID: 85013196214     PISSN: None     EISSN: 2296634X     Source Type: Journal    
DOI: 10.3389/fcell.2016.00070     Document Type: Article
Times cited : (10)

References (45)
  • 1
    • 84962069613 scopus 로고    scopus 로고
    • Vaccination with necroptotic cancer cells induces efficient anti-tumor immunity
    • Aaes, T. L., Kaczmarek, A., Delvaeye, T., De Craene, B., De Koker, S., Heyndrickx, L., et al. (2016). Vaccination with necroptotic cancer cells induces efficient anti-tumor immunity. Cell Rep. 15, 274-287. doi: 10.1016/j.celrep.2016.03.037
    • (2016) Cell Rep , vol.15 , pp. 274-287
    • Aaes, T.L.1    Kaczmarek, A.2    Delvaeye, T.3    De Craene, B.4    De Koker, S.5    Heyndrickx, L.6
  • 2
    • 33847030394 scopus 로고    scopus 로고
    • Regulation of NF-kappaB activity and keratinocyte differentiation by the RIP4 protein: implications for cutaneous wound repair
    • Adams, S., Pankow, S., Werner, S., and Munz, B. (2007). Regulation of NF-kappaB activity and keratinocyte differentiation by the RIP4 protein: implications for cutaneous wound repair. J. Invest. Dermatol. 127, 538-544. doi: 10.1038/sj.jid.5700588
    • (2007) J. Invest. Dermatol , vol.127 , pp. 538-544
    • Adams, S.1    Pankow, S.2    Werner, S.3    Munz, B.4
  • 3
    • 84860668802 scopus 로고    scopus 로고
    • Lethal inflammasome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota
    • Ayres, J. S., Trinidad, N. J., and Vance, R. E. (2012). Lethal inflammasome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota. Nat. Med. 18, 799-806. doi: 10.1038/nm.2729
    • (2012) Nat. Med , vol.18 , pp. 799-806
    • Ayres, J.S.1    Trinidad, N.J.2    Vance, R.E.3
  • 4
    • 84901678314 scopus 로고    scopus 로고
    • Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice
    • Berger, S. B., Kasparcova, V., Hoffman, S., Swift, B., Dare, L., Schaeffer, M., et al. (2014). Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice. J. Immunol. 192, 5476-5480. doi: 10.4049/jimmunol.1400499
    • (2014) J. Immunol , vol.192 , pp. 5476-5480
    • Berger, S.B.1    Kasparcova, V.2    Hoffman, S.3    Swift, B.4    Dare, L.5    Schaeffer, M.6
  • 5
    • 80755132824 scopus 로고    scopus 로고
    • The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation
    • Bonnet, M. C., Preukschat, D., Welz, P. S., van Loo, G., Ermolaeva, M. A., Bloch, W., et al. (2011). The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation. Immunity 35, 572-582. doi: 10.1016/j.immuni.2011.08.014
    • (2011) Immunity , vol.35 , pp. 572-582
    • Bonnet, M.C.1    Preukschat, D.2    Welz, P.S.3    van Loo, G.4    Ermolaeva, M.A.5    Bloch, W.6
  • 6
    • 0033965946 scopus 로고    scopus 로고
    • A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes
    • Chan, F. K., and Lenardo, M. J. (2000). A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes. Eur. J. Immunol. 30, 652-660. doi: 10.1002/1521-4141(200002)30:2<652::AID-IMMU652>3.0.CO;2-L
    • (2000) Eur. J. Immunol , vol.30 , pp. 652-660
    • Chan, F.K.1    Lenardo, M.J.2
  • 7
    • 84927671957 scopus 로고    scopus 로고
    • Programmed necrosis in the cross talk of cell death and inflammation
    • Chan, F. K., Luz, N. F., and Moriwaki, K. (2015). Programmed necrosis in the cross talk of cell death and inflammation. Annu. Rev. Immunol. 33, 79-106. doi: 10.1146/annurev-immunol-032414-112248
    • (2015) Annu. Rev. Immunol , vol.33 , pp. 79-106
    • Chan, F.K.1    Luz, N.F.2    Moriwaki, K.3
  • 8
    • 66449133280 scopus 로고    scopus 로고
    • Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
    • Cho, Y. S., Challa, S., Moquin, D., Genga, R., Ray, T. D., Guildford, M., et al. (2009). Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137, 1112-1123. doi: 10.1016/j.cell.2009.05.037
    • (2009) Cell , vol.137 , pp. 1112-1123
    • Cho, Y.S.1    Challa, S.2    Moquin, D.3    Genga, R.4    Ray, T.D.5    Guildford, M.6
  • 9
    • 68949086679 scopus 로고    scopus 로고
    • Enhanced cytoprotective effects of the inhibitor of apoptosis protein cellular IAP1 through stabilization with TRAF2
    • Csomos, R. A., Brady, G. F., and Duckett, C. S. (2009). Enhanced cytoprotective effects of the inhibitor of apoptosis protein cellular IAP1 through stabilization with TRAF2. J. Biol. Chem. 284, 20531-20539. doi: 10.1074/jbc.M109.029983
    • (2009) J. Biol. Chem , vol.284 , pp. 20531-20539
    • Csomos, R.A.1    Brady, G.F.2    Duckett, C.S.3
  • 10
    • 84907210946 scopus 로고    scopus 로고
    • RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
    • Dannappel, M., Vlantis, K., Kumari, S., Polykratis, A., Kim, C., Wachsmuth, L., et al. (2014). RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature 513, 90-94. doi: 10.1038/nature13608
    • (2014) Nature , vol.513 , pp. 90-94
    • Dannappel, M.1    Vlantis, K.2    Kumari, S.3    Polykratis, A.4    Kim, C.5    Wachsmuth, L.6
  • 12
    • 84901386193 scopus 로고    scopus 로고
    • RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3
    • Dillon, C. P., Weinlich, R., Rodriguez, D. A., Cripps, J. G., Quarato, G., Gurung, P., et al. (2014). RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3. Cell 157, 1189-1202. doi: 10.1016/j.cell.2014.04.018
    • (2014) Cell , vol.157 , pp. 1189-1202
    • Dillon, C.P.1    Weinlich, R.2    Rodriguez, D.A.3    Cripps, J.G.4    Quarato, G.5    Gurung, P.6
  • 13
    • 34548437549 scopus 로고    scopus 로고
    • Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain
    • Feng, S., Yang, Y., Mei, Y., Ma, L., Zhu, D. E., Hoti, N., et al. (2007). Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain. Cell. Signal. 19, 2056-2067. doi: 10.1016/j.cellsig.2007.05.016
    • (2007) Cell. Signal , vol.19 , pp. 2056-2067
    • Feng, S.1    Yang, Y.2    Mei, Y.3    Ma, L.4    Zhu, D.E.5    Hoti, N.6
  • 14
    • 84948703488 scopus 로고    scopus 로고
    • Receptor-Interacting protein kinase 3 deficiency delays cutaneous wound healing
    • Godwin, A., Sharma, A., Yang, W. L., Wang, Z., Nicastro, J., Coppa, G. F., et al. (2015). Receptor-Interacting protein kinase 3 deficiency delays cutaneous wound healing. PLoS ONE 10:e0140514. doi: 10.1371/journal.pone.0140514
    • (2015) PLoS ONE , vol.10
    • Godwin, A.1    Sharma, A.2    Yang, W.L.3    Wang, Z.4    Nicastro, J.5    Coppa, G.F.6
  • 15
    • 80052845560 scopus 로고    scopus 로고
    • Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis
    • Gunther, C., Martini, E., Wittkopf, N., Amann, K., Weigmann, B., Neumann, H., et al. (2011). Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis. Nature 477, 335-339. doi: 10.1038/nature10400
    • (2011) Nature , vol.477 , pp. 335-339
    • Gunther, C.1    Martini, E.2    Wittkopf, N.3    Amann, K.4    Weigmann, B.5    Neumann, H.6
  • 16
    • 66749183275 scopus 로고    scopus 로고
    • Receptor Interacting protein kinase-3 determines cellular necrotic response to TNF-a
    • He, S., Wang, L., Miao, L., Du, F., Zhao, L., and Wang, X. (2009). Receptor Interacting protein kinase-3 determines cellular necrotic response to TNF-a Cell 137, 1100-1111. doi: 10.1016/j.cell.2009.05.021
    • (2009) Cell , vol.137 , pp. 1100-1111
    • He, S.1    Wang, L.2    Miao, L.3    Du, F.4    Zhao, L.5    Wang, X.6
  • 17
    • 84901649808 scopus 로고    scopus 로고
    • RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition
    • Kaiser, W. J., Daley-Bauer, L. P., Thapa, R. J., Mandal, P., Berger, S. B., Huang, C., et al. (2014). RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition. Proc. Natl. Acad. Sci. U.S.A. 111, 7753-7758. doi: 10.1073/pnas.1401857111
    • (2014) Proc. Natl. Acad. Sci. U.S.A , vol.111 , pp. 7753-7758
    • Kaiser, W.J.1    Daley-Bauer, L.P.2    Thapa, R.J.3    Mandal, P.4    Berger, S.B.5    Huang, C.6
  • 19
    • 84932601454 scopus 로고    scopus 로고
    • Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3
    • Kang, S., Fernandes-Alnemri, T., Rogers, C., Mayes, L., Wang, Y., Dillon, C., et al. (2015). Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3. Nat. Commun. 6:7515. doi: 10.1038/ncomms8515
    • (2015) Nat. Commun , vol.6 , pp. 7515
    • Kang, S.1    Fernandes-Alnemri, T.2    Rogers, C.3    Mayes, L.4    Wang, Y.5    Dillon, C.6
  • 20
    • 0035892888 scopus 로고    scopus 로고
    • TNF type 2 receptor (p75) lowers the threshold of T cell activation
    • Kim, E. Y., and Teh, H. S. (2001). TNF type 2 receptor (p75) lowers the threshold of T cell activation. J. Immunol. 167, 6812-6820. doi: 10.4049/jimmunol.167.12.6812
    • (2001) J. Immunol , vol.167 , pp. 6812-6820
    • Kim, E.Y.1    Teh, H.S.2
  • 21
    • 4644296132 scopus 로고    scopus 로고
    • Critical role of TNF receptor type-2 (p75) as a costimulator for IL-2 induction and T cell survival: a functional link to CD28
    • Kim, E. Y., and Teh, H. S. (2004). Critical role of TNF receptor type-2 (p75) as a costimulator for IL-2 induction and T cell survival: a functional link to CD28. J. Immunol. 173, 4500-4509. doi: 10.4049/jimmunol.173.7.4500
    • (2004) J. Immunol , vol.173 , pp. 4500-4509
    • Kim, E.Y.1    Teh, H.S.2
  • 22
    • 77954224522 scopus 로고    scopus 로고
    • TNFR2-deficient memory CD8 T cells provide superior protection against tumor cell growth
    • Kim, E. Y., Teh, S. J., Yang, J., Chow, M. T., and Teh, H. S. (2009). TNFR2-deficient memory CD8 T cells provide superior protection against tumor cell growth. J. Immunol. 183, 6051-6057. doi: 10.4049/jimmunol.0803482
    • (2009) J. Immunol , vol.183 , pp. 6051-6057
    • Kim, E.Y.1    Teh, S.J.2    Yang, J.3    Chow, M.T.4    Teh, H.S.5
  • 23
    • 70350484946 scopus 로고    scopus 로고
    • Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease
    • Kovalenko, A., Kim, J. C., Kang, T. B., Rajput, A., Bogdanov, K., Dittrich-Breiholz, O., et al. (2009). Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J. Exp. Med. 206, 2161-2177. doi: 10.1084/jem.20090616
    • (2009) J. Exp. Med , vol.206 , pp. 2161-2177
    • Kovalenko, A.1    Kim, J.C.2    Kang, T.B.3    Rajput, A.4    Bogdanov, K.5    Dittrich-Breiholz, O.6
  • 24
    • 84923674191 scopus 로고    scopus 로고
    • RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
    • Lawlor, K. E., Khan, N., Mildenhall, A., Gerlic, M., Croker, B. A., D'Cruz, A. A., et al. (2015). RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL. Nat. Commun. 6:6282. doi: 10.1038/ncomms7282
    • (2015) Nat. Commun , vol.6 , pp. 6282
    • Lawlor, K.E.1    Khan, N.2    Mildenhall, A.3    Gerlic, M.4    Croker, B.A.5    D'Cruz, A.A.6
  • 25
    • 63649143438 scopus 로고    scopus 로고
    • Dynamic expression of epidermal caspase 8 simulates a wound healing response
    • Lee, P., Lee, D. J., Chan, C., Chen, S. W., Ch'en, I., and Jamora, C. (2009). Dynamic expression of epidermal caspase 8 simulates a wound healing response. Nature 458, 519-523. doi: 10.1038/nature07687
    • (2009) Nature , vol.458 , pp. 519-523
    • Lee, P.1    Lee, D.J.2    Chan, C.3    Chen, S.W.4    Ch'en, I.5    Jamora, C.6
  • 26
    • 78650667554 scopus 로고    scopus 로고
    • Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8
    • Li, C., Lasse, S., Lee, P., Nakasaki, M., Chen, S. W., Yamasaki, K., et al. (2010). Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8. Proc. Natl. Acad. Sci. U.S.A. 107, 22249-22254. doi: 10.1073/pnas.1009751108
    • (2010) Proc. Natl. Acad. Sci. U.S.A , vol.107 , pp. 22249-22254
    • Li, C.1    Lasse, S.2    Lee, P.3    Nakasaki, M.4    Chen, S.W.5    Yamasaki, K.6
  • 27
    • 0033214236 scopus 로고    scopus 로고
    • Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
    • Lin, Y., Devin, A., Rodriguez, Y., and Liu, Z. G. (1999). Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev. 13, 2514-2526. doi: 10.1101/gad.13.19.2514
    • (1999) Genes Dev , vol.13 , pp. 2514-2526
    • Lin, Y.1    Devin, A.2    Rodriguez, Y.3    Liu, Z.G.4
  • 28
    • 84908128377 scopus 로고    scopus 로고
    • The necroptosis adaptor RIPK3 promotes injury-induced cytokine expression and tissue repair
    • Moriwaki, K., Balaji, S., McQuade, T., Malhotra, N., Kang, J., and Chan, F. K. (2014). The necroptosis adaptor RIPK3 promotes injury-induced cytokine expression and tissue repair. Immunity 41, 567-578. doi: 10.1016/j.immuni.2014.09.016
    • (2014) Immunity , vol.41 , pp. 567-578
    • Moriwaki, K.1    Balaji, S.2    McQuade, T.3    Malhotra, N.4    Kang, J.5    Chan, F.K.6
  • 29
    • 84922570928 scopus 로고    scopus 로고
    • A RIPK3-caspase 8 complex mediates atypical pro-IL-1beta processing
    • Moriwaki, K., Bertin, J., Gough, P. J., and Chan, F. K. (2015a). A RIPK3-caspase 8 complex mediates atypical pro-IL-1beta processing. J. Immunol. 194, 1938-1944. doi: 10.4049/jimmunol.1402167
    • (2015) J. Immunol , vol.194 , pp. 1938-1944
    • Moriwaki, K.1    Bertin, J.2    Gough, P.J.3    Chan, F.K.4
  • 30
    • 84927660982 scopus 로고    scopus 로고
    • Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death
    • Moriwaki, K., Bertin, J., Gough, P. J., Orlowski, G. M., and Chan, F. K. (2015b). Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death. Cell Death Dis. 6:e1636. doi: 10.1038/cddis.2015.16
    • (2015) Cell Death Dis , vol.6
    • Moriwaki, K.1    Bertin, J.2    Gough, P.J.3    Orlowski, G.M.4    Chan, F.K.5
  • 31
    • 84899062708 scopus 로고    scopus 로고
    • Necrosis-dependent and independent signaling of the RIP kinases in inflammation
    • Moriwaki, K., and Chan, F. K. (2014). Necrosis-dependent and independent signaling of the RIP kinases in inflammation. Cytokine Growth Factor Rev. 25, 167-174. doi: 10.1016/j.cytogfr.2013.12.013
    • (2014) Cytokine Growth Factor Rev , vol.25 , pp. 167-174
    • Moriwaki, K.1    Chan, F.K.2
  • 32
    • 84968538437 scopus 로고    scopus 로고
    • RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury
    • [Epub ahead of print]
    • Newton, K., Dugger, D. L., Maltzman, A., Greve, J. M., Hedehus, M., Martin-McNulty, B., et al. (2016). RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury. Cell Death Differ. doi: 10.1038/cdd.2016.46. [Epub ahead of print]
    • (2016) Cell Death Differ
    • Newton, K.1    Dugger, D.L.2    Maltzman, A.3    Greve, J.M.4    Hedehus, M.5    Martin-McNulty, B.6
  • 33
    • 84897088275 scopus 로고    scopus 로고
    • Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis
    • Newton, K., Dugger, D. L., Wickliffe, K. E., Kapoor, N., de Almagro, M. C., Vucic, D., et al. (2014). Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis. Science 343, 1357-1360. doi: 10.1126/science.1249361
    • (2014) Science , vol.343 , pp. 1357-1360
    • Newton, K.1    Dugger, D.L.2    Wickliffe, K.E.3    Kapoor, N.4    de Almagro, M.C.5    Vucic, D.6
  • 34
    • 79952810024 scopus 로고    scopus 로고
    • Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
    • Oberst, A., Dillon, C. P., Weinlich, R., McCormick, L. L., Fitzgerald, P., Pop, C., et al. (2011). Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 471, 363-367. doi: 10.1038/nature09852
    • (2011) Nature , vol.471 , pp. 363-367
    • Oberst, A.1    Dillon, C.P.2    Weinlich, R.3    McCormick, L.L.4    Fitzgerald, P.5    Pop, C.6
  • 35
    • 84922602504 scopus 로고    scopus 로고
    • Necroptosis and its role in inflammation
    • Pasparakis, M., and Vandenabeele, P. (2015). Necroptosis and its role in inflammation. Nature 517, 311-320. doi: 10.1038/nature14191
    • (2015) Nature , vol.517 , pp. 311-320
    • Pasparakis, M.1    Vandenabeele, P.2
  • 36
    • 84893726744 scopus 로고    scopus 로고
    • Necroptosis is active in children with inflammatory bowel disease and contributes to heighten intestinal inflammation
    • Pierdomenico, M., Negroni, A., Stronati, L., Vitali, R., Prete, E., Bertin, J., et al. (2014). Necroptosis is active in children with inflammatory bowel disease and contributes to heighten intestinal inflammation. Am. J. Gastroenterol. 109, 279-287. doi: 10.1038/ajg.2013.403
    • (2014) Am. J. Gastroenterol , vol.109 , pp. 279-287
    • Pierdomenico, M.1    Negroni, A.2    Stronati, L.3    Vitali, R.4    Prete, E.5    Bertin, J.6
  • 37
    • 84901422731 scopus 로고    scopus 로고
    • RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
    • Rickard, J. A., O'Donnell, J. A., Evans, J. M., Lalaoui, N., Poh, A. R., Rogers, T., et al. (2014). RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis. Cell 157, 1175-1188. doi: 10.1016/j.cell.2014.04.019
    • (2014) Cell , vol.157 , pp. 1175-1188
    • Rickard, J.A.1    O'Donnell, J.A.2    Evans, J.M.3    Lalaoui, N.4    Poh, A.R.5    Rogers, T.6
  • 38
    • 84964317387 scopus 로고    scopus 로고
    • The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression
    • Seifert, L., Werba, G., Tiwari, S., Giao Ly, N. N., Alothman, S., Alqunaibit, D., et al. (2016). The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression. Nature 532, 245-249. doi: 10.1038/nature17403
    • (2016) Nature , vol.532 , pp. 245-249
    • Seifert, L.1    Werba, G.2    Tiwari, S.3    Giao Ly, N.N.4    Alothman, S.5    Alqunaibit, D.6
  • 39
    • 84907197966 scopus 로고    scopus 로고
    • RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis
    • Takahashi, N., Vereecke, L., Bertrand, M. J., Duprez, L., Berger, S. B., Divert, T., et al. (2014). RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis. Nature 513, 95-99. doi: 10.1038/nature13706
    • (2014) Nature , vol.513 , pp. 95-99
    • Takahashi, N.1    Vereecke, L.2    Bertrand, M.J.3    Duprez, L.4    Berger, S.B.5    Divert, T.6
  • 40
    • 43049152912 scopus 로고    scopus 로고
    • TNF-alpha induces two distinct caspase-8 activation pathways
    • Wang, L., Du, F., and Wang, X. (2008). TNF-alpha induces two distinct caspase-8 activation pathways. Cell 133, 693-703. doi: 10.1016/j.cell.2008.03.036
    • (2008) Cell , vol.133 , pp. 693-703
    • Wang, L.1    Du, F.2    Wang, X.3
  • 41
    • 80052850704 scopus 로고    scopus 로고
    • FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
    • Welz, P. S., Wullaert, A., Vlantis, K., Kondylis, V., Fernandez-Majada, V., Ermolaeva, M., et al. (2011). FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature 477, 330-334. doi: 10.1038/nature10273
    • (2011) Nature , vol.477 , pp. 330-334
    • Welz, P.S.1    Wullaert, A.2    Vlantis, K.3    Kondylis, V.4    Fernandez-Majada, V.5    Ermolaeva, M.6
  • 42
    • 34347262689 scopus 로고    scopus 로고
    • Chemically induced mouse models of intestinal inflammation
    • Wirtz, S., Neufert, C., Weigmann, B., and Neurath, M. F. (2007). Chemically induced mouse models of intestinal inflammation. Nat. Protoc. 2, 541-546. doi: 10.1038/nprot.2007.41
    • (2007) Nat. Protoc , vol.2 , pp. 541-546
    • Wirtz, S.1    Neufert, C.2    Weigmann, B.3    Neurath, M.F.4
  • 43
    • 7144263731 scopus 로고    scopus 로고
    • FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis
    • Yeh, W. C., Pompa, J. L., McCurrach, M. E., Shu, H. B., Elia, A. J., Shahinian, A., et al. (1998). FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 279, 1954-1958. doi: 10.1126/science.279.5358.1954
    • (1998) Science , vol.279 , pp. 1954-1958
    • Yeh, W.C.1    Pompa, J.L.2    McCurrach, M.E.3    Shu, H.B.4    Elia, A.J.5    Shahinian, A.6
  • 44
    • 79952780505 scopus 로고    scopus 로고
    • Functional complementation between FADD and RIP1 in embryos and lymphocytes
    • Zhang, H., Zhou, X., McQuade, T., Li, J., Chan, F. K., and Zhang, J. (2011). Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature 471, 373-376. doi: 10.1038/nature09878
    • (2011) Nature , vol.471 , pp. 373-376
    • Zhang, H.1    Zhou, X.2    McQuade, T.3    Li, J.4    Chan, F.K.5    Zhang, J.6
  • 45
    • 0032546387 scopus 로고    scopus 로고
    • Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1
    • Zhang, J., Cado, D., Chen, A., Kabra, N. H., and Winoto, A. (1998). Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature 392, 296-300. doi: 10.1038/32681
    • (1998) Nature , vol.392 , pp. 296-300
    • Zhang, J.1    Cado, D.2    Chen, A.3    Kabra, N.H.4    Winoto, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.