Design of strategies to study the metabolic profile of highly polar compounds in plasma by reversed-phase liquid chromatography–high resolution mass spectrometry

Journal of Chromatography A

Volumn 1490, Issue , 2017, Pages 156-165

  Sánchez López, Elena ^a   Crego, Antonio L ^a   Marina, María Luisa ^a  

^a UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

9 Fluorenylmethyloxycarbonyl; Hydrophilic compounds; Liquid chromatography high resolution mass spectrometry; Metabolic profile; Plasma; Ultrafiltration

Indexed keywords

AMINES; AMINO ACIDS; CHROMATOGRAPHY; HYDROPHILICITY; LIQUIDS; MASS SPECTROMETRY; METABOLISM; PLASMAS; PROTEINS; SPECTROMETRY; ULTRAFILTRATION;

9-FLUORENYLMETHYLOXYCARBONYL; HYDROPHILIC COMPOUNDS; LIQUID CHROMATOGRAPHY-HIGH RESOLUTION MASS SPECTROMETRIES; METABOLIC PROFILES; PENTAFLUOROPHENYL COLUMNS; PRIMARY AND SECONDARY AMINE; PROTEINOGENIC AMINO ACIDS; REVERSED PHASE LIQUID-CHROMATOGRAPHY;

LIQUID CHROMATOGRAPHY;

9 FLUORENYLMETHYLOXYCARBONYL; ALANINE; ARGININE; ASPARAGINE; ASPARTIC ACID; BETA ALANINE; BOMBESIN[6-13][6 DEXTRO PENTAFLUOROPHENYLALANINE 11 DEXTRO ALANINE] METHYL ESTER; CITRULLINE; GLUTAMIC ACID; GLUTAMINE; GLYCINE; HISTAMINE; HISTIDINE; ISOLEUCINE; LEUCINE; LYSINE; METHIONINE; NORVALINE; ORNITHINE; PHENYLALANINE; PROLINE; PYROGLUTAMIC ACID; REAGENT; SERINE; SEROTONIN; THREONINE; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG; VALINE; AMINO ACID;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; CELL POLARITY; COMPLEX FORMATION; CONTROLLED STUDY; DATA PROCESSING; DERIVATIZATION; ELUTION; HIGH TEMPERATURE; HYDROGEN BOND; HYDROPHILIC INTERACTION CHROMATOGRAPHY; HYDROPHILICITY; HYDROPHOBICITY; ION CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLOMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRECIPITATION; RAT; RETENTION TIME; REVERSED PHASE LIQUID CHROMATOGRAPHY; STATIC ELECTRICITY; TIME OF FLIGHT MASS SPECTROMETRY; ULTRAFILTRATION; WETTABILITY; CHEMICAL PHENOMENA; CHEMISTRY; METHODOLOGY; PROCEDURES;

AMINO ACIDS; CHROMATOGRAPHY, REVERSE-PHASE; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MASS SPECTROMETRY; METABOLOMICS; RESEARCH DESIGN;

EID: 85013040074     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2017.02.029     Document Type: Article

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