Systematic comparison of sensitivity between hydrophilic interaction liquid chromatography and reversed phase liquid chromatography coupled with mass spectrometry

Journal of Chromatography A

Volumn 1312, Issue , 2013, Pages 49-57

  Periat, Aurélie ^a   Boccard, Julien ^a   Veuthey, Jean Luc ^a   Rudaz, Serge ^a   Guillarme, Davy ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Electrospray ionization; HILIC MS; Hydrophilic interaction liquid chromatography; Pharmaceutical compounds; Sensitivity

Indexed keywords

HILIC-MS; HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHIES; PHARMACEUTICAL COMPOUNDS; PHYSICOCHEMICAL PROPERTY; REVERSED PHASE LIQUID-CHROMATOGRAPHY; SENSITIVITY; SENSITIVITY ENHANCEMENTS; SIGNAL TO NOISE (S/N) RATIOS;

ELECTROSPRAY IONIZATION; IONIZATION; LIQUID CHROMATOGRAPHY;

MASS SPECTROMETRY;

ACEBUTOLOL; ADENOSINE; ALPRAZOLAM; ALPRENOLOL; AMFEBUTAMONE; AMPHETAMINE; BISOPROLOL; BUPRENORPHINE; BUSPIRONE; CINCHOCAINE; CLONIDINE; COCAINE; CODEINE; DEXTROMETHORPHAN; DIAMORPHINE; DIHYDROCODEINE; DILTIAZEM; DOXEPIN; FENTANYL; FLURAZEPAM; HOMOCOCAINE; HYDROXYZINE; IMIPRAMINE; KETAMINE; LIDOCAINE; METHADONE; METHAMPHETAMINE; MORPHINE 6 ACETATE; PHENAZONE; UNINDEXED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STRUCTURE; ELUTION; FLOW RATE; HYDROPHILIC INTERACTION CHROMATOGRAPHY; INTERMETHOD COMPARISON; IONIZATION; MASS SPECTROMETRY; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON TRANSPORT; REVERSED PHASE LIQUID CHROMATOGRAPHY; SENSITIVITY ANALYSIS; SIGNAL NOISE RATIO;

ELECTROSPRAY IONIZATION; HILIC-MS; HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY; PHARMACEUTICAL COMPOUNDS; SENSITIVITY;

ACETONITRILES; CHROMATOGRAPHY, LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MASS SPECTROMETRY; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; SIGNAL-TO-NOISE RATIO; STATISTICS, NONPARAMETRIC;

EID: 84884355099     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2013.08.097     Document Type: Article

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