-
1
-
-
0346058347
-
Immunotherapy of malignant diseases Challenges and strategies
-
[1] Ko, E.C., Wang, X., Ferrone, S., Immunotherapy of malignant diseases Challenges and strategies. Int. Arch. Allergy Immunol. 132:4 (2003), 294–309.
-
(2003)
Int. Arch. Allergy Immunol.
, vol.132
, Issue.4
, pp. 294-309
-
-
Ko, E.C.1
Wang, X.2
Ferrone, S.3
-
2
-
-
0034066072
-
Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis
-
[2] Weinstein, I.B., Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis. Carcinogenesis 21:5 (2000), 857–864.
-
(2000)
Carcinogenesis
, vol.21
, Issue.5
, pp. 857-864
-
-
Weinstein, I.B.1
-
3
-
-
84881109637
-
The molecular basis of targeting protein kinases in cancer therapeutics
-
[3] Tsai, C.J., Nussinov, R., The molecular basis of targeting protein kinases in cancer therapeutics. Semin. Cancer Biol. 23:August (4) (2013), 235–242.
-
(2013)
Semin. Cancer Biol.
, vol.23
, Issue.August (4)
, pp. 235-242
-
-
Tsai, C.J.1
Nussinov, R.2
-
4
-
-
84877773278
-
Tyrosine kinase inhibitors: their on-target toxicities as potential indicators of efficacy
-
[4] Shah, D.R., Shah, R.R., Morganroth, J., Tyrosine kinase inhibitors: their on-target toxicities as potential indicators of efficacy. Drug Saf. 36:6 (2013), 413–426.
-
(2013)
Drug Saf.
, vol.36
, Issue.6
, pp. 413-426
-
-
Shah, D.R.1
Shah, R.R.2
Morganroth, J.3
-
5
-
-
12944325331
-
A listing of human tumor antigens recognized by T cells: March 2004 update
-
[5] Novellino, L.C.C., Parmiani, G., A listing of human tumor antigens recognized by T cells: March 2004 update. Cancer Immunol. Immunother. 54:3 (2005), 187–207.
-
(2005)
Cancer Immunol. Immunother.
, vol.54
, Issue.3
, pp. 187-207
-
-
Novellino, L.C.C.1
Parmiani, G.2
-
6
-
-
22044442973
-
Tyrosine kinases as targets for cancer therapy
-
[6] Krause, D.S., Van Etten, R.A., Tyrosine kinases as targets for cancer therapy. N. Engl. J. Med. 353:2 (2005), 172–187.
-
(2005)
N. Engl. J. Med.
, vol.353
, Issue.2
, pp. 172-187
-
-
Krause, D.S.1
Van Etten, R.A.2
-
7
-
-
0033786922
-
Protein tyrosine kinase structure and function
-
[7] Hubbard, S.R., Till, J.H., Protein tyrosine kinase structure and function. Annu. Rev. Biochem. 69 (2000), 373–398.
-
(2000)
Annu. Rev. Biochem.
, vol.69
, pp. 373-398
-
-
Hubbard, S.R.1
Till, J.H.2
-
8
-
-
0036159121
-
The Ror receptor tyrosine kinase family
-
[8] Forrester, W.C., The Ror receptor tyrosine kinase family. Cell. Mol. Life Sci. 59:1 (2002), 83–96.
-
(2002)
Cell. Mol. Life Sci.
, vol.59
, Issue.1
, pp. 83-96
-
-
Forrester, W.C.1
-
9
-
-
0028146767
-
A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity
-
[9] Nishikawa, R.J.X., Harmon, R.C., et al. A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity. Proc. Natl. Acad. Sci. U. S. A. 91:16 (1994), 7727–7731.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, Issue.16
, pp. 7727-7731
-
-
Nishikawa, R.J.X.1
Harmon, R.C.2
-
10
-
-
0035150912
-
The molecular biology of cancer
-
[10] Bertram, J.S., The molecular biology of cancer. Mol. Aspects Med. 21:December (6) (2000), 167–223.
-
(2000)
Mol. Aspects Med.
, vol.21
, Issue.December (6)
, pp. 167-223
-
-
Bertram, J.S.1
-
11
-
-
42449110211
-
Overexpression of orphan receptor tyrosine kinase Ror1 as a putative tumor-associated antigen in Iranian patients with acute lymphoblastic leukemia
-
[11] Shabani, M., Asgarian-Omran, H., Jeddi-Tehrani, M., Vossough, P., Faranoush, M., Sharifian, R.A., Toughe, G.R., Kordmahin, M., Khoshnoodi, J., Roohi, A., Tavoosi, N., Mellstedt, H., Rabbani, H., Shokri, F., Overexpression of orphan receptor tyrosine kinase Ror1 as a putative tumor-associated antigen in Iranian patients with acute lymphoblastic leukemia. Tumour Biol. 28:6 (2007), 318–326, 10.1159/000121405.
-
(2007)
Tumour Biol.
, vol.28
, Issue.6
, pp. 318-326
-
-
Shabani, M.1
Asgarian-Omran, H.2
Jeddi-Tehrani, M.3
Vossough, P.4
Faranoush, M.5
Sharifian, R.A.6
Toughe, G.R.7
Kordmahin, M.8
Khoshnoodi, J.9
Roohi, A.10
Tavoosi, N.11
Mellstedt, H.12
Rabbani, H.13
Shokri, F.14
-
12
-
-
84904155440
-
Cancer treatment and survivorship statistics, 2014
-
[12] DeSantis, C.E., Lin, C.C., Mariotto, A.B., Siegel, R.L., Stein, K.D., Kramer, J.L., Alteri, R., Robbins, A.S., Jemal, A., Cancer treatment and survivorship statistics, 2014. CA Cancer J. Clin. 64:July–August (4) (2014), 252–271.
-
(2014)
CA Cancer J. Clin.
, vol.64
, Issue.July–August (4)
, pp. 252-271
-
-
DeSantis, C.E.1
Lin, C.C.2
Mariotto, A.B.3
Siegel, R.L.4
Stein, K.D.5
Kramer, J.L.6
Alteri, R.7
Robbins, A.S.8
Jemal, A.9
-
13
-
-
0027074850
-
A novel family of cell surface receptors with tyrosine kinase-like domain
-
[13] Masiakowski, P.C.R., A novel family of cell surface receptors with tyrosine kinase-like domain. J. Biol. Chem. 267 (1992), 26181–26190.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 26181-26190
-
-
Masiakowski, P.C.R.1
-
14
-
-
0033607015
-
A C. elegans Ror receptor tyrosine kinase regulates cell motility and asymmetric cell division
-
[14] Forrester, W.C., Dell, M., Perens, E., Garriga, G., A C. elegans Ror receptor tyrosine kinase regulates cell motility and asymmetric cell division. Nature 400 (1999), 881–885.
-
(1999)
Nature
, vol.400
, pp. 881-885
-
-
Forrester, W.C.1
Dell, M.2
Perens, E.3
Garriga, G.4
-
15
-
-
80053985778
-
Post-translational modifications regulate signalling by Ror1
-
[15] Kaucká, M.K.P., Plevová, K., Pavlová, Š., Procházková, J., Janovská, P., Valnohová, J., Kozubík, A., Pospíšilová, Š., Bryja, V., Post-translational modifications regulate signalling by Ror1. Acta Physiol. 203 (2011), 351–362.
-
(2011)
Acta Physiol.
, vol.203
, pp. 351-362
-
-
Kaucká, M.K.P.1
Plevová, K.2
Pavlová, Š.3
Procházková, J.4
Janovská, P.5
Valnohová, J.6
Kozubík, A.7
Pospíšilová, Š.8
Bryja, V.9
-
16
-
-
77954078799
-
Nuclear localization of orphan receptor protein kinase (Ror1) is mediated through the juxtamembrane domain
-
[16] Tseng, H.-C., Lyu, P.-C., Lin, W-c., Nuclear localization of orphan receptor protein kinase (Ror1) is mediated through the juxtamembrane domain. BMC Cell Biol., 11(1), 2010, 48.
-
(2010)
BMC Cell Biol.
, vol.11
, Issue.1
, pp. 48
-
-
Tseng, H.-C.1
Lyu, P.-C.2
Lin, W.-C.3
-
17
-
-
84855168544
-
Cytoskeleton network and cellular migration modulated by nuclear-localized receptor tyrosine kinase ROR1
-
[17] Tseng, H.-C., Kao, H.-W., Ho, M.-R., Chen, Y.-R., Lin, T.-W., Lyu, P.-C., et al. Cytoskeleton network and cellular migration modulated by nuclear-localized receptor tyrosine kinase ROR1. Anticancer Res. 31:12 (2011), 4239–4249.
-
(2011)
Anticancer Res.
, vol.31
, Issue.12
, pp. 4239-4249
-
-
Tseng, H.-C.1
Kao, H.-W.2
Ho, M.-R.3
Chen, Y.-R.4
Lin, T.-W.5
Lyu, P.-C.6
-
18
-
-
54249099446
-
Ror receptor tyrosine kinases: orphans no more
-
[18] Green, J.L., Kuntz, S.G., Sternberg, P.W., Ror receptor tyrosine kinases: orphans no more. Trends Cell Biol. 18:11 (2008), 536–544.
-
(2008)
Trends Cell Biol.
, vol.18
, Issue.11
, pp. 536-544
-
-
Green, J.L.1
Kuntz, S.G.2
Sternberg, P.W.3
-
19
-
-
79954622199
-
Ror1 is a pseudokinase that is crucial for Met-driven tumorigenesis
-
[19] Gentile, A., Lazzari, L., Benvenuti, S., Trusolino, L., Comoglio, P.M., Ror1 is a pseudokinase that is crucial for Met-driven tumorigenesis. Cancer Res. 71:8 (2011), 3132–3141.
-
(2011)
Cancer Res.
, vol.71
, Issue.8
, pp. 3132-3141
-
-
Gentile, A.1
Lazzari, L.2
Benvenuti, S.3
Trusolino, L.4
Comoglio, P.M.5
-
20
-
-
84904206209
-
ROR1, an embryonic protein with an emerging role in cancer biology
-
[20] Borcherding, N., Kusner, D., Liu, G.-H., Zhang, W., ROR1, an embryonic protein with an emerging role in cancer biology. Protein Cell 5:7 (2014), 496–502.
-
(2014)
Protein Cell
, vol.5
, Issue.7
, pp. 496-502
-
-
Borcherding, N.1
Kusner, D.2
Liu, G.-H.3
Zhang, W.4
-
21
-
-
6544275956
-
Spatio‐temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system
-
[21] Oishi, I., Takeuchi, S., Hashimoto, R., Nagabukuro, A., Ueda, T., Liu, Z.J., et al. Spatio‐temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system. Genes Cells 4:1 (1999), 41–56.
-
(1999)
Genes Cells
, vol.4
, Issue.1
, pp. 41-56
-
-
Oishi, I.1
Takeuchi, S.2
Hashimoto, R.3
Nagabukuro, A.4
Ueda, T.5
Liu, Z.J.6
-
22
-
-
0027074850
-
A novel family of cell surface receptors with tyrosine kinase-like domain
-
[22] Masiakowski, P., Carroll, R.D., A novel family of cell surface receptors with tyrosine kinase-like domain. J. Biol. Chem. 267:36 (1992), 26181–26190.
-
(1992)
J. Biol. Chem.
, vol.267
, Issue.36
, pp. 26181-26190
-
-
Masiakowski, P.1
Carroll, R.D.2
-
23
-
-
84869049935
-
Crosstalk between ROR1 and the pre-B Cell receptor promotes survival of t (1;19) acute lymphoblastic leukemia
-
[23] Bicocca, V.T., Chang, B.H., Masouleh, B.K., Muschen, M., Loriaux, M.M., Druker, B.J., Tyner, J.W., Crosstalk between ROR1 and the pre-B Cell receptor promotes survival of t (1;19) acute lymphoblastic leukemia. Cancer Cell 22 (2012), 656–667.
-
(2012)
Cancer Cell
, vol.22
, pp. 656-667
-
-
Bicocca, V.T.1
Chang, B.H.2
Masouleh, B.K.3
Muschen, M.4
Loriaux, M.M.5
Druker, B.J.6
Tyner, J.W.7
-
24
-
-
84863384604
-
NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma
-
[24] Yamaguchi, T., Yanagisawa, K., Sugiyama, R., Hosono, Y., Shimada, Y., Arima, C., et al. NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma. Cancer Cell 21:3 (2012), 348–361.
-
(2012)
Cancer Cell
, vol.21
, Issue.3
, pp. 348-361
-
-
Yamaguchi, T.1
Yanagisawa, K.2
Sugiyama, R.3
Hosono, Y.4
Shimada, Y.5
Arima, C.6
-
25
-
-
84904326600
-
Evolutionary divergence in the catalytic activity of the CAM-1 ROR1 and ROR2 kinase domains
-
[25] Bainbridge, T.W., DeAlmeida, V.I., Izrael-Tomasevic, A., Chalouni, C., Pan, B., Goldsmith, J., et al. Evolutionary divergence in the catalytic activity of the CAM-1 ROR1 and ROR2 kinase domains. PLoS One, 9(7), 2014, e102695.
-
(2014)
PLoS One
, vol.9
, Issue.7
, pp. e102695
-
-
Bainbridge, T.W.1
DeAlmeida, V.I.2
Izrael-Tomasevic, A.3
Chalouni, C.4
Pan, B.5
Goldsmith, J.6
-
26
-
-
0034948866
-
Expression of the receptor tyrosine kinase genes, Ror1 and Ror2, during mouse development
-
[26] Matsuda, T., Nomi, M., Ikeya, M., Kani, S., Oishi, I., Terashima, T., et al. Expression of the receptor tyrosine kinase genes, Ror1 and Ror2, during mouse development. Mech. Dev. 105:1 (2001), 153–156.
-
(2001)
Mech. Dev.
, vol.105
, Issue.1
, pp. 153-156
-
-
Matsuda, T.1
Nomi, M.2
Ikeya, M.3
Kani, S.4
Oishi, I.5
Terashima, T.6
-
27
-
-
0033607015
-
elegans Ror receptor tyrosine kinase regulates cell motility and asymmetric cell division
-
[27] Forrester, W.C., Dell, M., Perens, E., Garriga, G.A.C., elegans Ror receptor tyrosine kinase regulates cell motility and asymmetric cell division. Nature 400:6747 (1999), 881–885.
-
(1999)
Nature
, vol.400
, Issue.6747
, pp. 881-885
-
-
Forrester, W.C.1
Dell, M.2
Perens, E.3
Garriga, G.A.C.4
-
28
-
-
0344925865
-
Functional analysis of the domains of the C elegans Ror receptor tyrosine kinase CAM-1
-
[28] Kim, C., Forrester, W.C., Functional analysis of the domains of the C elegans Ror receptor tyrosine kinase CAM-1. Dev. Biol. 264:2 (2003), 376–390.
-
(2003)
Dev. Biol.
, vol.264
, Issue.2
, pp. 376-390
-
-
Kim, C.1
Forrester, W.C.2
-
29
-
-
0035947581
-
Localization of disulfide bonds in the frizzled module of Ror1 receptor tyrosine kinase
-
[29] Roszmusz, E., Patthy, A., Trexler, M., Patthy, L., Localization of disulfide bonds in the frizzled module of Ror1 receptor tyrosine kinase. J. Biol. Chem. 276:21 (2001), 18485–18490.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.21
, pp. 18485-18490
-
-
Roszmusz, E.1
Patthy, A.2
Trexler, M.3
Patthy, L.4
-
30
-
-
14044263637
-
Neurite extension in central neurons: a novel role for the receptor tyrosine kinases Ror1 and Ror2
-
[30] Paganoni, S., Ferreira, A., Neurite extension in central neurons: a novel role for the receptor tyrosine kinases Ror1 and Ror2. J. Cell Sci. 118:Jaunuary Pt 2 (2005), 433–446.
-
(2005)
J. Cell Sci.
, vol.118
, Issue.Jaunuary Pt 2
, pp. 433-446
-
-
Paganoni, S.1
Ferreira, A.2
-
31
-
-
84953240034
-
ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1. ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1
-
[31] Yamaguchi, T., Lu, C., Ida, L., Yanagisawa, K., Usukura, J., Cheng, J., Hotta, N., Shimada, Y., Isomura, H., Suzuki, M., Fujimoto, T., Takahashi, T., ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1. ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1. Nat. Commun., 7(January), 2016, 10060.
-
(2016)
Nat. Commun.
, vol.7
, Issue.January
, pp. 10060
-
-
Yamaguchi, T.1
Lu, C.2
Ida, L.3
Yanagisawa, K.4
Usukura, J.5
Cheng, J.6
Hotta, N.7
Shimada, Y.8
Isomura, H.9
Suzuki, M.10
Fujimoto, T.11
Takahashi, T.12
-
32
-
-
0037237125
-
Expression and function of the Ror-family receptor tyrosine kinases during development: lessons from genetic analyses of nematodes, mice, and humans
-
[32] Yoda, A., Oishi, I., Minami, Y., Expression and function of the Ror-family receptor tyrosine kinases during development: lessons from genetic analyses of nematodes, mice, and humans. J. Recept. Signal Transduct. 23:1 (2003), 1–15.
-
(2003)
J. Recept. Signal Transduct.
, vol.23
, Issue.1
, pp. 1-15
-
-
Yoda, A.1
Oishi, I.2
Minami, Y.3
-
33
-
-
0035192873
-
Loss of mRor1 enhances the heart and skeletal abnormalities in mRor2-deficient mice: redundant and pleiotropic functions of mRor1 and mRor2 receptor tyrosine kinases
-
[33] Nomi, M., Oishi, I., Kani, S., Suzuki, H., Matsuda, T., Yoda, A., et al. Loss of mRor1 enhances the heart and skeletal abnormalities in mRor2-deficient mice: redundant and pleiotropic functions of mRor1 and mRor2 receptor tyrosine kinases. Mol. Cell. Biol. 21:24 (2001), 8329–8335.
-
(2001)
Mol. Cell. Biol.
, vol.21
, Issue.24
, pp. 8329-8335
-
-
Nomi, M.1
Oishi, I.2
Kani, S.3
Suzuki, H.4
Matsuda, T.5
Yoda, A.6
-
34
-
-
0034051682
-
Ror2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate development
-
[34] DeChiara, T.M., Kimble, R.B., Poueymirou, W.T., Rojas, J., Masiakowski, P., Valenzuela, D.M., et al. Ror2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate development. Nat. Genet. 24:3 (2000), 271–274.
-
(2000)
Nat. Genet.
, vol.24
, Issue.3
, pp. 271-274
-
-
DeChiara, T.M.1
Kimble, R.B.2
Poueymirou, W.T.3
Rojas, J.4
Masiakowski, P.5
Valenzuela, D.M.6
-
35
-
-
6744265274
-
Mouse Ror2 receptor tyrosine kinase is required for the heart development and limb formation
-
[35] Takeuchi, S., Takeda, K., Oishi, I., Nomi, M., Ikeya, M., Itoh, K., et al. Mouse Ror2 receptor tyrosine kinase is required for the heart development and limb formation. Genes Cells 5:1 (2000), 71–78.
-
(2000)
Genes Cells
, vol.5
, Issue.1
, pp. 71-78
-
-
Takeuchi, S.1
Takeda, K.2
Oishi, I.3
Nomi, M.4
Ikeya, M.5
Itoh, K.6
-
36
-
-
0034838873
-
Simons JP Expression of the Ror1 and Ror2 receptor tyrosine kinase genes during mouse development
-
[36] Al-Shawi, R.A.S., Underwood, C., Simons JP Expression of the Ror1 and Ror2 receptor tyrosine kinase genes during mouse development. Dev. Genes Evol. 211 (2001), 161–171.
-
(2001)
Dev. Genes Evol.
, vol.211
, pp. 161-171
-
-
Al-Shawi, R.A.S.1
Underwood, C.2
-
37
-
-
0034948866
-
Expression of the receptor tyrosine kinase genes, Ror1 and Ror2, during mouse development
-
[37] Matsuda, T.N.M., Ikeya, M., Kani, S., Oishi, I., Terashima, T., Takada, S., Minami, Y., Expression of the receptor tyrosine kinase genes, Ror1 and Ror2, during mouse development. Mech. Dev. 105 (2001), 153–156.
-
(2001)
Mech. Dev.
, vol.105
, pp. 153-156
-
-
Matsuda, T.N.M.1
Ikeya, M.2
Kani, S.3
Oishi, I.4
Terashima, T.5
Takada, S.6
Minami, Y.7
-
38
-
-
38949156617
-
Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia
-
[38] Baskar, S., Kwong, K.Y., Hofer, T., Levy, J.M., Kennedy, M.G., Lee, E., Staudt, L.M., Wilson, W.H., Wiestner, A., Rader, C., Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia. Clin. Cancer Res. 14 (2008), 396–404.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 396-404
-
-
Baskar, S.1
Kwong, K.Y.2
Hofer, T.3
Levy, J.M.4
Kennedy, M.G.5
Lee, E.6
Staudt, L.M.7
Wilson, W.H.8
Wiestner, A.9
Rader, C.10
-
39
-
-
78649461928
-
The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor
-
[39] Hudecek, M.S.T., Baskar, S., Lupo-Stanghellini, M.T., Nishida, T., Yamamoto, T.N., Bleakley, M., Turtle, C.J., Chang, W.-C., Greisman, H.A., et al. The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor. Blood 116 (2010), 4532–4541.
-
(2010)
Blood
, vol.116
, pp. 4532-4541
-
-
Hudecek, M.S.T.1
Baskar, S.2
Lupo-Stanghellini, M.T.3
Nishida, T.4
Yamamoto, T.N.5
Bleakley, M.6
Turtle, C.J.7
Chang, W.-C.8
Greisman, H.A.9
-
40
-
-
47249140824
-
Ror1, a cell surface receptor tyrosine kinase is expressed in chronic lymphocytic leukemia and may serve as a putative target for therapy
-
[40] Daneshmanesh, A.H., Mikaelsson, E., Jeddi-Tehrani, M., Bayat, A.A., Ghods, R., Ostadkarampour, M., Akhondi, M., Lagercrantz, S., Larsson, C., Osterborg, A., Shokri, F., Mellstedt, H., Rabbani, H., Ror1, a cell surface receptor tyrosine kinase is expressed in chronic lymphocytic leukemia and may serve as a putative target for therapy. Int. J. Cancer 123 (2008), 1190–1195.
-
(2008)
Int. J. Cancer
, vol.123
, pp. 1190-1195
-
-
Daneshmanesh, A.H.1
Mikaelsson, E.2
Jeddi-Tehrani, M.3
Bayat, A.A.4
Ghods, R.5
Ostadkarampour, M.6
Akhondi, M.7
Lagercrantz, S.8
Larsson, C.9
Osterborg, A.10
Shokri, F.11
Mellstedt, H.12
Rabbani, H.13
-
41
-
-
79952337584
-
ROR1 expression is not a unique marker of CLL
-
[41] Barna, G.M.R., Timár, B., Tömböl, J., Csende, Z., Sebestyén, A., Bödör, C., Csernus, B., Reiniger, L., Peták, I., et al. ROR1 expression is not a unique marker of CLL. Hematol. Oncol. 29 (2011), 17–21.
-
(2011)
Hematol. Oncol.
, vol.29
, pp. 17-21
-
-
Barna, G.M.R.1
Timár, B.2
Tömböl, J.3
Csende, Z.4
Sebestyén, A.5
Bödör, C.6
Csernus, B.7
Reiniger, L.8
Peták, I.9
-
42
-
-
84863251015
-
ROR1 is expressed in human breast cancer and associated with enhanced tumor-cell growth
-
[42] Zhang, S.C.L., Cui, B., Chuang, H.-Y., Yu, J., Wang-Rodriguez, J., Tang, L., Chen, G., Basak, G.W., Kipps, T.J., ROR1 is expressed in human breast cancer and associated with enhanced tumor-cell growth. PLoS One, 7, 2012, e31127.
-
(2012)
PLoS One
, vol.7
, pp. e31127
-
-
Zhang, S.C.L.1
Cui, B.2
Chuang, H.-Y.3
Yu, J.4
Wang-Rodriguez, J.5
Tang, L.6
Chen, G.7
Basak, G.W.8
Kipps, T.J.9
-
43
-
-
20444419344
-
Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
-
[43] MacKeigan, J.P., Murphy, L.O., Blenis, J., Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. Nat. Cell Biol. 7:6 (2005), 591–600.
-
(2005)
Nat. Cell Biol.
, vol.7
, Issue.6
, pp. 591-600
-
-
MacKeigan, J.P.1
Murphy, L.O.2
Blenis, J.3
-
44
-
-
77958519836
-
Silencing of ROR1 and FMOD with siRNA results in apoptosis of CLL cells
-
[44] Choudhury, A., Derkow, K., Daneshmanesh, A.H., Mikaelsson, E., Kiaii, S., Kokhaei, P., et al. Silencing of ROR1 and FMOD with siRNA results in apoptosis of CLL cells. Br. J. Haematol. 151:4 (2010), 327–335.
-
(2010)
Br. J. Haematol.
, vol.151
, Issue.4
, pp. 327-335
-
-
Choudhury, A.1
Derkow, K.2
Daneshmanesh, A.H.3
Mikaelsson, E.4
Kiaii, S.5
Kokhaei, P.6
-
45
-
-
84927578271
-
The receptor tyrosine kinase ROR1—an oncofetal antigen for targeted cancer therapy
-
[45] Hojjat-Farsangi, M., Moshfegh, A., Daneshmanesh, A.H., Khan, A.S., Mikaelsson, E., Osterborg, A., Mellstedt, H., The receptor tyrosine kinase ROR1—an oncofetal antigen for targeted cancer therapy. Semin. Cancer Biol. 29 (2014), 21–31.
-
(2014)
Semin. Cancer Biol.
, vol.29
, pp. 21-31
-
-
Hojjat-Farsangi, M.1
Moshfegh, A.2
Daneshmanesh, A.H.3
Khan, A.S.4
Mikaelsson, E.5
Osterborg, A.6
Mellstedt, H.7
-
46
-
-
84875993102
-
Orphan receptor tyrosine kinases ROR1 and ROR2 in hematological malignancies
-
[46] Daneshmanesh, A.H., Porwit, A., Hojjat-Farsangi, M., Jeddi-Tehrani, M., Tamm, K.P., Grandér, D., et al. Orphan receptor tyrosine kinases ROR1 and ROR2 in hematological malignancies. Leuk. Lymphoma 54:4 (2013), 843–850.
-
(2013)
Leuk. Lymphoma
, vol.54
, Issue.4
, pp. 843-850
-
-
Daneshmanesh, A.H.1
Porwit, A.2
Hojjat-Farsangi, M.3
Jeddi-Tehrani, M.4
Tamm, K.P.5
Grandér, D.6
-
47
-
-
80052602132
-
Comparative expression profile of orphan receptor tyrosine kinase ROR1 in Iranian patients with lymphoid and myeloid leukemias
-
[47] Shabani, M., Asgarian-Omran, H., Hojjat-Farsangi, M., Vossough, P., Sharifian, R.A., Toughe, G.R., et al. Comparative expression profile of orphan receptor tyrosine kinase ROR1 in Iranian patients with lymphoid and myeloid leukemias. Avicenna J. Med. Biotechnol. 3:3 (2011), 119–125.
-
(2011)
Avicenna J. Med. Biotechnol.
, vol.3
, Issue.3
, pp. 119-125
-
-
Shabani, M.1
Asgarian-Omran, H.2
Hojjat-Farsangi, M.3
Vossough, P.4
Sharifian, R.A.5
Toughe, G.R.6
-
48
-
-
84869166013
-
Kipps TJ The onco-embryonic antigen ROR1 is expressed by a variety of human cancers
-
[48] Zhang, S.C.L., Wang-Rodriguez, J., Zhang, L., Cui, B., Frankel, W., Wu, R., Kipps TJ The onco-embryonic antigen ROR1 is expressed by a variety of human cancers. Am. J. Pathol. 181 (2012), 1903–1910.
-
(2012)
Am. J. Pathol.
, vol.181
, pp. 1903-1910
-
-
Zhang, S.C.L.1
Wang-Rodriguez, J.2
Zhang, L.3
Cui, B.4
Frankel, W.5
Wu, R.6
-
49
-
-
84927580139
-
Anti-ROR1 monoclonal antibodies induce apoptosis in pancreatic cancer cells via the PI3-kinase/AKT/mTOR pathway
-
[49] Daneshmanesh, A.H., Hojjat-Farsangi, M., Moshfegh, A., Mikaelsson, E., Khan, A.S., Österborg, A., et al. Anti-ROR1 monoclonal antibodies induce apoptosis in pancreatic cancer cells via the PI3-kinase/AKT/mTOR pathway. Cancer Res., 74(19 Suppl), 2014, 4770.
-
(2014)
Cancer Res.
, vol.74
, Issue.19
, pp. 4770
-
-
Daneshmanesh, A.H.1
Hojjat-Farsangi, M.2
Moshfegh, A.3
Mikaelsson, E.4
Khan, A.S.5
Österborg, A.6
-
50
-
-
85012238028
-
Cirmtuzumab vedotin (UC-961ADC3), an anti-ROR1-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for ROR1-positive leukemia and solid tumors
-
[50] Widhopf, G.F., Prussak, C.E., Wu, C.C., Sadarangani, A., Zhang, S., Lao, F., et al. Cirmtuzumab vedotin (UC-961ADC3), an anti-ROR1-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for ROR1-positive leukemia and solid tumors. Blood, 122(21), 2013, 1637-.
-
(2013)
Blood
, vol.122
, Issue.21
, pp. 1637-
-
-
Widhopf, G.F.1
Prussak, C.E.2
Wu, C.C.3
Sadarangani, A.4
Zhang, S.5
Lao, F.6
-
51
-
-
0031436969
-
B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues
-
[51] Frank, D.A., Mahajan, S., Ritz, J., B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues. J. Clin. Invest., 100(12), 1997, 3140.
-
(1997)
J. Clin. Invest.
, vol.100
, Issue.12
, pp. 3140
-
-
Frank, D.A.1
Mahajan, S.2
Ritz, J.3
-
52
-
-
77955639050
-
Stat3 activates the receptor tyrosine kinase like orphan receptor-1 gene in chronic lymphocytic leukemia cells
-
[52] Li, P., Harris, D., Liu, Z., Liu, J., Keating, M., Estrov, Z., Stat3 activates the receptor tyrosine kinase like orphan receptor-1 gene in chronic lymphocytic leukemia cells. PLoS One, 5(7), 2010, e11859.
-
(2010)
PLoS One
, vol.5
, Issue.7
, pp. e11859
-
-
Li, P.1
Harris, D.2
Liu, Z.3
Liu, J.4
Keating, M.5
Estrov, Z.6
-
53
-
-
84886240815
-
The tyrosine kinase receptor ROR1 is constitutively phosphorylated in chronic lymphocytic leukemia (CLL) cells
-
[53] Hojjat-Farsangi, M., Khan, A.S., Daneshmanesh, A.H., Moshfegh, A., Sandin, Å., Mansouri, L., et al. The tyrosine kinase receptor ROR1 is constitutively phosphorylated in chronic lymphocytic leukemia (CLL) cells. PLoS One, 8(10), 2013, e78339.
-
(2013)
PLoS One
, vol.8
, Issue.10
, pp. e78339
-
-
Hojjat-Farsangi, M.1
Khan, A.S.2
Daneshmanesh, A.H.3
Moshfegh, A.4
Sandin, Å.5
Mansouri, L.6
-
54
-
-
36849046794
-
Homodimerization of Ror2 tyrosine kinase receptor induces 14-3-3β phosphorylation and promotes osteoblast differentiation and bone formation
-
[54] Liu, Y., Ross, J.F., Bodine, P.V., Billiard, J., Homodimerization of Ror2 tyrosine kinase receptor induces 14-3-3β phosphorylation and promotes osteoblast differentiation and bone formation. Mol. Endocrinol. 21:12 (2007), 3050–3061.
-
(2007)
Mol. Endocrinol.
, vol.21
, Issue.12
, pp. 3050-3061
-
-
Liu, Y.1
Ross, J.F.2
Bodine, P.V.3
Billiard, J.4
-
55
-
-
54249096215
-
Wnt5a induces homodimerization and activation of Ror2 receptor tyrosine kinase
-
[55] Liu, Y., Rubin, B., Bodine, P.V., Billiard, J., Wnt5a induces homodimerization and activation of Ror2 receptor tyrosine kinase. J. Cell. Biochem. 105:2 (2008), 497–502.
-
(2008)
J. Cell. Biochem.
, vol.105
, Issue.2
, pp. 497-502
-
-
Liu, Y.1
Rubin, B.2
Bodine, P.V.3
Billiard, J.4
-
56
-
-
10244267459
-
Modulation of GDF5/BRI-b signalling through interaction with the tyrosine kinase receptor Ror2
-
[56] Sammar, M., Stricker, S., Schwabe, G.C., Sieber, C., Hartung, A., Hanke, M., et al. Modulation of GDF5/BRI-b signalling through interaction with the tyrosine kinase receptor Ror2. Genes Cells 9:12 (2004), 1227–1238.
-
(2004)
Genes Cells
, vol.9
, Issue.12
, pp. 1227-1238
-
-
Sammar, M.1
Stricker, S.2
Schwabe, G.C.3
Sieber, C.4
Hartung, A.5
Hanke, M.6
-
57
-
-
54949106904
-
Mammalian glycosylation in immunity
-
[57] Marth, J.D., Grewal, P.K., Mammalian glycosylation in immunity. Nat. Rev. Immunol. 8:11 (2008), 874–887.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, Issue.11
, pp. 874-887
-
-
Marth, J.D.1
Grewal, P.K.2
-
58
-
-
84892611828
-
ROR1 can interact with TCL1 and enhance leukemogenesis in Eμ-TCL1 transgenic mice
-
[58] Widhopf, G.F., Cui, B., Ghia, E.M., Chen, L., Messer, K., Shen, Z., Briggs, S.P., Croce, C.M., Kipps, T.J., ROR1 can interact with TCL1 and enhance leukemogenesis in Eμ-TCL1 transgenic mice. Proc. Natl. Acad. Sci. U. S. A. 111:January (2) (2014), 793–798.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, Issue.January (2)
, pp. 793-798
-
-
Widhopf, G.F.1
Cui, B.2
Ghia, E.M.3
Chen, L.4
Messer, K.5
Shen, Z.6
Briggs, S.P.7
Croce, C.M.8
Kipps, T.J.9
-
59
-
-
43249130717
-
Flow cytometric immunophenotyping for hematologic neoplasms
-
[59] Craig, Fiona E., Foon, Kenneth A., Flow cytometric immunophenotyping for hematologic neoplasms. Blood 111 (2008), 3941–3967.
-
(2008)
Blood
, vol.111
, pp. 3941-3967
-
-
Craig, F.E.1
Foon, K.A.2
-
60
-
-
84938074563
-
Introduction to a series of reviews on chronic lymphocytic leukemia
-
[60] Byrd, John C., Introduction to a series of reviews on chronic lymphocytic leukemia. Blood, 126, 2015, 427.
-
(2015)
Blood
, vol.126
, pp. 427
-
-
Byrd, J.C.1
-
61
-
-
84959454423
-
The molecular pathogenesis of chronic lymphocytic leukaemia
-
[61] Fabbri, G., Dalla-Favera, R., The molecular pathogenesis of chronic lymphocytic leukaemia. Nat. Rev. Cancer 16 (2016), 145–162.
-
(2016)
Nat. Rev. Cancer
, vol.16
, pp. 145-162
-
-
Fabbri, G.1
Dalla-Favera, R.2
-
62
-
-
80052102768
-
Use of the receptor tyrosine kinase-like orphan receptor 1 (ROR1) as a diagnostic tool in chronic lymphocytic leukemia (CLL)
-
[62] Uhrmacher, S., Schmidt, C., Erdfelder, F., Poll-Wolbeck, S.J., Gehrke, I., Hallek, M., et al. Use of the receptor tyrosine kinase-like orphan receptor 1 (ROR1) as a diagnostic tool in chronic lymphocytic leukemia (CLL). Leuk. Res. 35:10 (2011), 1360–1366.
-
(2011)
Leuk. Res.
, vol.35
, Issue.10
, pp. 1360-1366
-
-
Uhrmacher, S.1
Schmidt, C.2
Erdfelder, F.3
Poll-Wolbeck, S.J.4
Gehrke, I.5
Hallek, M.6
-
63
-
-
84860912693
-
Monoclonal antibodies against ROR1 induce apoptosis of chronic lymphocytic leukemia (CLL) cells
-
[63] Daneshmanesh, A., Hojjat-Farsangi, M., Khan, A., Jeddi-Tehrani, M., Akhondi, M., Bayat, A., et al. Monoclonal antibodies against ROR1 induce apoptosis of chronic lymphocytic leukemia (CLL) cells. Leukemia 26:6 (2012), 1348–1355.
-
(2012)
Leukemia
, vol.26
, Issue.6
, pp. 1348-1355
-
-
Daneshmanesh, A.1
Hojjat-Farsangi, M.2
Khan, A.3
Jeddi-Tehrani, M.4
Akhondi, M.5
Bayat, A.6
-
64
-
-
34247594390
-
International standardized approach for flow cytometric residual disease monitoring in chronic lymphocytic leukaemia
-
[64] Rawstron, A., Villamor, N., Ritgen, M., Böttcher, S., Ghia, P., Zehnder, J., et al. International standardized approach for flow cytometric residual disease monitoring in chronic lymphocytic leukaemia. Leukemia 21:5 (2007), 956–964.
-
(2007)
Leukemia
, vol.21
, Issue.5
, pp. 956-964
-
-
Rawstron, A.1
Villamor, N.2
Ritgen, M.3
Böttcher, S.4
Ghia, P.5
Zehnder, J.6
-
65
-
-
33747078748
-
Fludarabine in chronic lymphocytic leukaemia
-
[65] Elter, T., Hallek, M., Engert, A., Fludarabine in chronic lymphocytic leukaemia. Expert Opin. Pharmacother. 7:12 (2006), 1641–1651.
-
(2006)
Expert Opin. Pharmacother.
, vol.7
, Issue.12
, pp. 1641-1651
-
-
Elter, T.1
Hallek, M.2
Engert, A.3
-
66
-
-
84860907341
-
Targeting malignant B cells with an immunotoxin against ROR1
-
[66] Baskar, S., Wiestner, A., Wilson, W.H., Pastan, I., Rader, C., Targeting malignant B cells with an immunotoxin against ROR1. MAbs 4:May–June (3) (2012), 349–361.
-
(2012)
MAbs
, vol.4
, Issue.May–June (3)
, pp. 349-361
-
-
Baskar, S.1
Wiestner, A.2
Wilson, W.H.3
Pastan, I.4
Rader, C.5
-
67
-
-
84927568982
-
Preclinical development of ROR1 peptide based vaccine with activity against chronic lymphocytic leukemia in ROR1 transgenic mice
-
[67] Cui, B., Widhopf, G.F., Chen, L., Rassenti, L., Wang, Z., Ma, S., et al. Preclinical development of ROR1 peptide based vaccine with activity against chronic lymphocytic leukemia in ROR1 transgenic mice. Blood, 122(21), 2013, 4174.
-
(2013)
Blood
, vol.122
, Issue.21
, pp. 4174
-
-
Cui, B.1
Widhopf, G.F.2
Chen, L.3
Rassenti, L.4
Wang, Z.5
Ma, S.6
-
68
-
-
84883759491
-
Active immunotherapy in HER2 overexpressing breast cancer: current status and future perspectives
-
[68] Milani, A., Sangiolo, D., Montemurro, F., Aglietta, M., Valabrega, G., Active immunotherapy in HER2 overexpressing breast cancer: current status and future perspectives. Ann. Oncol. 24:July (7) (2013), 1740–1748.
-
(2013)
Ann. Oncol.
, vol.24
, Issue.July (7)
, pp. 1740-1748
-
-
Milani, A.1
Sangiolo, D.2
Montemurro, F.3
Aglietta, M.4
Valabrega, G.5
-
69
-
-
38949156617
-
Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia
-
[69] Baskar, S., Kwong, K.Y., Hofer, T., Levy, J.M., Kennedy, M.G., Lee, E., et al. Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia. Clin. Cancer Res. 14:2 (2008), 396–404.
-
(2008)
Clin. Cancer Res.
, vol.14
, Issue.2
, pp. 396-404
-
-
Baskar, S.1
Kwong, K.Y.2
Hofer, T.3
Levy, J.M.4
Kennedy, M.G.5
Lee, E.6
-
70
-
-
84931053950
-
Receptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy
-
941-5519 (7)
-
[70] Shabani, M., Naseri, J., Shokri, F., Receptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy. Expert Opin. Ther. Targets 19:July (7) (2015), 941–955 941-5519 (7).
-
(2015)
Expert Opin. Ther. Targets
, vol.19
, Issue.July (7)
, pp. 941-955
-
-
Shabani, M.1
Naseri, J.2
Shokri, F.3
-
71
-
-
84889848914
-
Future prospects of monoclonal antibodies as magic bullets in immunotherapy
-
[71] Maleki, L.A., Baradaran, B., Majidi, J., Mohammadian, M., Shahneh, F.Z., Future prospects of monoclonal antibodies as magic bullets in immunotherapy. Hum. Antibodies 22:1–2 (2013), 9–13.
-
(2013)
Hum. Antibodies
, vol.22
, Issue.1-2
, pp. 9-13
-
-
Maleki, L.A.1
Baradaran, B.2
Majidi, J.3
Mohammadian, M.4
Shahneh, F.Z.5
-
72
-
-
84989306634
-
Phage display as a promising approach for vaccine development
-
[72] Aghebati-Maleki, L., Bakhshinejad, B., Baradaran, B., et al. Phage display as a promising approach for vaccine development. J. Biomed. Sci., 23, 2016, 66.
-
(2016)
J. Biomed. Sci.
, vol.23
, pp. 66
-
-
Aghebati-Maleki, L.1
Bakhshinejad, B.2
Baradaran, B.3
-
73
-
-
79958776633
-
Therapeutic potential and challenges of targeting receptor tyrosine kinase ROR1 with monoclonal antibodies in B-cell malignancies
-
[73] Yang, J., Baskar, S., Kwong, K.Y., Kennedy, M.G., Wiestner, A., Rader, C., Therapeutic potential and challenges of targeting receptor tyrosine kinase ROR1 with monoclonal antibodies in B-cell malignancies. PLoS One, 6(6), 2011, e21018.
-
(2011)
PLoS One
, vol.6
, Issue.6
, pp. e21018
-
-
Yang, J.1
Baskar, S.2
Kwong, K.Y.3
Kennedy, M.G.4
Wiestner, A.5
Rader, C.6
-
74
-
-
78349232462
-
Asymmetric tyrosine kinase arrangements in activation or autophosphorylation of receptor tyrosine kinases
-
[74] Bae, J.H., Schlessinger, J., Asymmetric tyrosine kinase arrangements in activation or autophosphorylation of receptor tyrosine kinases. Mol. Cells 29:5 (2010), 443–448.
-
(2010)
Mol. Cells
, vol.29
, Issue.5
, pp. 443-448
-
-
Bae, J.H.1
Schlessinger, J.2
-
75
-
-
0035864706
-
Distinct tyrosine autophosphorylation sites mediate induction of epithelial mesenchymal like transition by an activated ErbB-2/Neu receptor
-
[75] Khoury, H., Dankort, D.L., Sadekova, S., Naujokas, M.A., Muller, W.J., Park, M., Distinct tyrosine autophosphorylation sites mediate induction of epithelial mesenchymal like transition by an activated ErbB-2/Neu receptor. Oncogene 20:7 (2001), 788–799.
-
(2001)
Oncogene
, vol.20
, Issue.7
, pp. 788-799
-
-
Khoury, H.1
Dankort, D.L.2
Sadekova, S.3
Naujokas, M.A.4
Muller, W.J.5
Park, M.6
-
76
-
-
52049116971
-
CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation
-
[76] Noble, C., Mercer, K., Hussain, J., Carragher, L., Giblett, S., Hayward, R., et al. CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation. Mol. Cell 31:6 (2008), 862–872.
-
(2008)
Mol. Cell
, vol.31
, Issue.6
, pp. 862-872
-
-
Noble, C.1
Mercer, K.2
Hussain, J.3
Carragher, L.4
Giblett, S.5
Hayward, R.6
-
77
-
-
42949121156
-
Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a
-
[77] Fukuda, T., Chen, L., Endo, T., Tang, L., Lu, D., Castro, J.E., Widhopf, G.F., Rassenti, L.Z., Cantwell, M.J., Prussak, C.E., Carson, D.A., Kipps, T.J., Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a. Proc. Natl. Acad. Sci. U. S. A. 105 (2008), 3047–3052.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 3047-3052
-
-
Fukuda, T.1
Chen, L.2
Endo, T.3
Tang, L.4
Lu, D.5
Castro, J.E.6
Widhopf, G.F.7
Rassenti, L.Z.8
Cantwell, M.J.9
Prussak, C.E.10
Carson, D.A.11
Kipps, T.J.12
-
78
-
-
80051775476
-
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
-
[78] Kalos, M., Levine, B.L., Porter, D.L., Katz, S., Grupp, S.A., Bagg, A., et al. T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci. Transl. Med., 3(95), 2011, 95ra73.
-
(2011)
Sci. Transl. Med.
, vol.3
, Issue.95
, pp. 95ra73
-
-
Kalos, M.1
Levine, B.L.2
Porter, D.L.3
Katz, S.4
Grupp, S.A.5
Bagg, A.6
-
79
-
-
84863337890
-
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells
-
[79] Kochenderfer, J.N., Dudley, M.E., Feldman, S.A., Wilson, W.H., Spaner, D.E., Maric, I., et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells. Blood 119:12 (2012), 2709–2720.
-
(2012)
Blood
, vol.119
, Issue.12
, pp. 2709-2720
-
-
Kochenderfer, J.N.1
Dudley, M.E.2
Feldman, S.A.3
Wilson, W.H.4
Spaner, D.E.5
Maric, I.6
-
80
-
-
78549278144
-
Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
-
[80] Kochenderfer, J.N., Wilson, W.H., Janik, J.E., Dudley, M.E., Stetler-Stevenson, M., Feldman, S.A., et al. Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19. Blood 116:20 (2010), 4099–4102.
-
(2010)
Blood
, vol.116
, Issue.20
, pp. 4099-4102
-
-
Kochenderfer, J.N.1
Wilson, W.H.2
Janik, J.E.3
Dudley, M.E.4
Stetler-Stevenson, M.5
Feldman, S.A.6
-
81
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
[81] Morgan, R.A., Dudley, M.E., Wunderlich, J.R., Hughes, M.S., Yang, J.C., Sherry, R.M., et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 314:5796 (2006), 126–129.
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
Hughes, M.S.4
Yang, J.C.5
Sherry, R.M.6
-
82
-
-
80051720194
-
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
-
[82] Porter, D.L., Levine, B.L., Kalos, M., Bagg, A., June, C.H., Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. New Engl. J. Med. 365:8 (2011), 725–733.
-
(2011)
New Engl. J. Med.
, vol.365
, Issue.8
, pp. 725-733
-
-
Porter, D.L.1
Levine, B.L.2
Kalos, M.3
Bagg, A.4
June, C.H.5
-
83
-
-
0027471898
-
Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors
-
[83] Eshhar, Z., Waks, T., Gross, G., Schindler, D.G., Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors. Proc. Natl. Acad. Sci. U. S. A. 90:2 (1993), 720–724.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, Issue.2
, pp. 720-724
-
-
Eshhar, Z.1
Waks, T.2
Gross, G.3
Schindler, D.G.4
-
84
-
-
28544448646
-
Supernatural T cells: genetic modification of T cells for cancer therapy
-
[84] Kershaw, M.H., Teng, M.W., Smyth, M.J., Darcy, P.K., Supernatural T cells: genetic modification of T cells for cancer therapy. Nat. Rev. Immunol. 5:12 (2005), 928–940.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, Issue.12
, pp. 928-940
-
-
Kershaw, M.H.1
Teng, M.W.2
Smyth, M.J.3
Darcy, P.K.4
-
85
-
-
0037264471
-
Targeting tumours with genetically enhanced T lymphocytes
-
[85] Sadelain, M., Rivière, I., Brentjens, R., Targeting tumours with genetically enhanced T lymphocytes. Nat. Rev. Cancer 3:1 (2003), 35–45.
-
(2003)
Nat. Rev. Cancer
, vol.3
, Issue.1
, pp. 35-45
-
-
Sadelain, M.1
Rivière, I.2
Brentjens, R.3
-
86
-
-
84933510694
-
CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia
-
[86] Maude, Shannon L., Teachey, David T., Porter, David L., Grupp, Stephan A., CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia. Blood 125 (2015), 4017–4023.
-
(2015)
Blood
, vol.125
, pp. 4017-4023
-
-
Maude, S.L.1
Teachey, D.T.2
Porter, D.L.3
Grupp, S.A.4
-
87
-
-
80455179612
-
Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
-
[87] Brentjens, R.J., Rivière, I., Park, J.H., Davila, M.L., Wang, X., Stefanski, J., et al. Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias. Blood 118:18 (2011), 4817–4828.
-
(2011)
Blood
, vol.118
, Issue.18
, pp. 4817-4828
-
-
Brentjens, R.J.1
Rivière, I.2
Park, J.H.3
Davila, M.L.4
Wang, X.5
Stefanski, J.6
-
88
-
-
84879480191
-
Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells
-
[88] Hudecek, M., Lupo-Stanghellini, M.-T., Kosasih, P.L., Sommermeyer, D., Jensen, M.C., Rader, C., et al. Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells. Clin. Cancer Res. 19:12 (2013), 3153–3164.
-
(2013)
Clin. Cancer Res.
, vol.19
, Issue.12
, pp. 3153-3164
-
-
Hudecek, M.1
Lupo-Stanghellini, M.-T.2
Kosasih, P.L.3
Sommermeyer, D.4
Jensen, M.C.5
Rader, C.6
-
89
-
-
0036216405
-
(Gleevec) as a paradigm for cancer therapy
-
[89] STI571, B.J.D., (Gleevec) as a paradigm for cancer therapy. Trends Mol. Med 8:4 Suppl (2002), S14–8.
-
(2002)
Trends Mol. Med
, vol.8
, Issue.4
, pp. S14-8
-
-
STI571, B.J.D.1
-
90
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
[90] Davies, S.P., Reddy, H., Caivano, M., et al. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351:Pt 1 (2000), 95–105.
-
(2000)
Biochem. J.
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
-
91
-
-
84891317257
-
Discovery and preclinical characterization of novel small molecule TRK and ROS1 tyrosine kinase inhibitors for the treatment of cancer and inflammation
-
[91] Narayanan, R., Yepuru, M., Coss, C.C., et al. Discovery and preclinical characterization of novel small molecule TRK and ROS1 tyrosine kinase inhibitors for the treatment of cancer and inflammation. PLoS One, 8(12), 2013, e83380.
-
(2013)
PLoS One
, vol.8
, Issue.12
, pp. e83380
-
-
Narayanan, R.1
Yepuru, M.2
Coss, C.C.3
-
92
-
-
84883160397
-
Ibrutinib and novel BTK inhibitors in clinical development
-
[92] Akinleye, A., Chen, Y., Mukhi, N., et al. Ibrutinib and novel BTK inhibitors in clinical development. J. Hematol. Oncol., 6, 2013, 59.
-
(2013)
J. Hematol. Oncol.
, vol.6
, pp. 59
-
-
Akinleye, A.1
Chen, Y.2
Mukhi, N.3
-
93
-
-
84863011553
-
The Bruton tyrosine kinase inhibitor PCI- 32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo
-
[93] Ponader, S., Chen, S.S., Buggy, J.J., et al. The Bruton tyrosine kinase inhibitor PCI- 32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo. Blood 119:5 (2012), 1182–1189.
-
(2012)
Blood
, vol.119
, Issue.5
, pp. 1182-1189
-
-
Ponader, S.1
Chen, S.S.2
Buggy, J.J.3
-
94
-
-
84927608950
-
The PI3K/AKT/mTOR pathway is involved in direct apoptosis of CLL cells induced by ROR1 monoclonal antibodies
-
May
-
[94] Daneshmanesh, A.H., Hojjat-Farsangi, M., Moshfegh, A., Khan, A.S., Mikaelsson, E., Österborg, A., Mellstedt, H., The PI3K/AKT/mTOR pathway is involved in direct apoptosis of CLL cells induced by ROR1 monoclonal antibodies. Br. J. Haematol. 169:3 (2015 May), 455–458.
-
(2015)
Br. J. Haematol.
, vol.169
, Issue.3
, pp. 455-458
-
-
Daneshmanesh, A.H.1
Hojjat-Farsangi, M.2
Moshfegh, A.3
Khan, A.S.4
Mikaelsson, E.5
Österborg, A.6
Mellstedt, H.7
-
95
-
-
84890063283
-
Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2
-
[95] O'Connell, M.P., Marchbank, K., Webster, M.R., Valiga, A.A., Kaur, A., Vultur, A., et al. Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2. Cancer Discov. 3:12 (2013), 1378–1393.
-
(2013)
Cancer Discov.
, vol.3
, Issue.12
, pp. 1378-1393
-
-
O'Connell, M.P.1
Marchbank, K.2
Webster, M.R.3
Valiga, A.A.4
Kaur, A.5
Vultur, A.6
|