Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice

Nature Communications

Volumn 8, Issue , 2017, Pages

  Andres Hernando, Ana ^a   Li, Nanxing ^a   Cicerchi, Christina ^a   Inaba, Shinichiro ^a   Chen, Wei ^a,b   Roncal Jimenez, Carlos ^a   Le, Myphuong T ^a   Wempe, Michael F ^a   Milagres, Tamara ^a   Ishimoto, Takuji ^a   Fini, Mehdi ^a   Nakagawa, Takahiko ^a   Johnson, Richard J ^a   Lanaspa, Miguel A ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALDEHYDE REDUCTASE; FRUCTOKINASE; FRUCTOSE; LUTEOLIN; POLYOL; SORBITOL; URIC ACID; PROTECTIVE AGENT;

ENZYME ACTIVITY; GLUCOSE; INHIBITOR; INJURY; METABOLISM; OXIDATIVE STRESS; PATHOGENICITY;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; ENZYME INHIBITION; HUMAN; INFLAMMATION; KIDNEY CORTEX; KIDNEY DYSFUNCTION; KIDNEY INJURY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; RENAL PROTECTION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL LINE; COMPLICATION; DRUG EFFECT; GENETICS; ISCHEMIA; KIDNEY; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; URINE;

ANIMALIA; MUS;

ACUTE KIDNEY INJURY; ALDEHYDE REDUCTASE; ANIMALS; CELL LINE; FRUCTOKINASES; FRUCTOSE; HUMANS; ISCHEMIA; KIDNEY; LUTEOLIN; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS; PROTECTIVE AGENTS; URIC ACID;

EID: 85012307670     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms14181     Document Type: Article

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