Modulation of intestinal barrier and bacterial endotoxin production contributes to the beneficial effect of nicotinic acid on alcohol-induced endotoxemia and hepatic inflammation in rats

Biomolecules

Volumn 5, Issue 4, 2015, Pages 2643-2658

  Zhong, Wei ^a   Li, Qiong ^a   Zhang, Wenliang ^a   Sun, Qian ^a   Sun, Xinguo ^a   Zhou, Zhanxiang ^a  

^a UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

Author keywords

Alcohol; Endotoxemia; Gut permeability; Inflammation; Nicotinic acid

Indexed keywords

ACETALDEHYDE; ALCOHOL; ALDEHYDE DEHYDROGENASE ISOENZYME 1; CD163 ANTIGEN; CD68 ANTIGEN; CLAUDIN 1; CLAUDIN 5; CXCL1 CHEMOKINE; ENDOTOXIN; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; NICOTINIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN ZO1; TIGHT JUNCTION PROTEIN;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ARTICLE; DOWN REGULATION; EXPERIMENTAL ENDOTOXEMIA; HEPATITIS; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INTESTINAL BARRIER; MALE; NICOTINIC ACID DEFICIENCY; NONHUMAN; PERMEABILITY BARRIER; POLYMERASE CHAIN REACTION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; VITAMIN SUPPLEMENTATION; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; ENDOTOXEMIA; INTESTINE; LIVER DISEASES, ALCOHOLIC; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; ENDOTOXEMIA; ETHANOL; INTESTINES; LIVER DISEASES, ALCOHOLIC; MALE; NIACIN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 85012069122     PISSN: None     EISSN: 2218273X     Source Type: Journal    
DOI: 10.3390/biom5042643     Document Type: Article

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