-
1
-
-
78149405081
-
Ketosis and the ketogenic diet, 2010: Advances in treating epilepsy and other disorders
-
Freeman JM, Kossoff EH. Ketosis and the ketogenic diet, 2010: advances in treating epilepsy and other disorders. Adv Pediatr 2010; 57:315-329.
-
(2010)
Adv Pediatr
, vol.57
, pp. 315-329
-
-
Freeman, J.M.1
Kossoff, E.H.2
-
2
-
-
84866022656
-
The ketogenic diet as a treatment paradigm for diverse neurological disorders
-
Stafstrom CE, Rho JM. The ketogenic diet as a treatment paradigm for diverse neurological disorders. Front Pharmacol 2012; 3:59.
-
(2012)
Front Pharmacol
, vol.3
, pp. 59
-
-
Stafstrom, C.E.1
Rho, J.M.2
-
3
-
-
84899051589
-
Risk of seizure recurrence after achieving initial seizure freedom on the ketogenic diet
-
Taub KS, Kessler SK, Bergqvist AG. Risk of seizure recurrence after achieving initial seizure freedom on the ketogenic diet. Epilepsia 2014; 55:579-583.
-
(2014)
Epilepsia
, vol.55
, pp. 579-583
-
-
Taub, K.S.1
Kessler, S.K.2
Bergqvist, A.G.3
-
4
-
-
84938718749
-
How does the ketogenic diet induce anti-seizure effects?
-
Rho JM. How does the ketogenic diet induce anti-seizure effects? Neurosci Lett 2015; 637:4-10.
-
(2015)
Neurosci Lett
, vol.637
, pp. 4-10
-
-
Rho, J.M.1
-
5
-
-
84869095296
-
Mechanisms of ketogenic diet action
-
Noebels JL, Avoli M, Rogawski MA, et al., editors. 4th ed Bethesda (MD), USA: National Center for Biotechnology Information (US)
-
Masino SA, Rho JM. Mechanisms of ketogenic diet action. In: Noebels JL, Avoli M, Rogawski MA, et al., editors. Jaspers basic mechanisms of the epilepsies, 4th ed Bethesda (MD), USA: National Center for Biotechnology Information (US); 2012.
-
(2012)
Jaspers Basic Mechanisms of the Epilepsies
-
-
Masino, S.A.1
Rho, J.M.2
-
6
-
-
84871718480
-
The ketogenic diet: Metabolic influences on brain excitability and epilepsy
-
Lutas A, Yellen G. The ketogenic diet: metabolic influences on brain excitability and epilepsy. Trends Neurosci 2013; 36:32-40.
-
(2013)
Trends Neurosci
, vol.36
, pp. 32-40
-
-
Lutas, A.1
Yellen, G.2
-
7
-
-
84989842395
-
A prospective study on changes in blood levels of cholecystokinin-8 and leptin in patients with refractory epilepsy treated with the ketogenic diet
-
Lambrechts DA, Brandt-Wouters E, Verschuure P, et al. A prospective study on changes in blood levels of cholecystokinin-8 and leptin in patients with refractory epilepsy treated with the ketogenic diet. Epilepsy Res 2016; 127:87-92.
-
(2016)
Epilepsy Res
, vol.127
, pp. 87-92
-
-
Lambrechts, D.A.1
Brandt-Wouters, E.2
Verschuure, P.3
-
8
-
-
84944751908
-
Efficacy of the ketogenic diet for the treatment of refractory childhood epilepsy: Cerebrospinal fluid neurotransmitters and amino acid levels
-
Sariego-Jamardo A, Garcia-Cazorla A, Artuch R, et al. Efficacy of the ketogenic diet for the treatment of refractory childhood epilepsy: cerebrospinal fluid neurotransmitters and amino acid levels. Pediatr Neurol 2015; 53: 422-426.
-
(2015)
Pediatr Neurol
, vol.53
, pp. 422-426
-
-
Sariego-Jamardo, A.1
Garcia-Cazorla, A.2
Artuch, R.3
-
9
-
-
84948745029
-
Variants in KCNJ11 and BAD do not predict response to ketogenic dietary therapies for epilepsy
-
Schoeler NE, Leu C, White J, et al. Variants in KCNJ11 and BAD do not predict response to ketogenic dietary therapies for epilepsy. Epilepsy Res 2015; 118:22-28.
-
(2015)
Epilepsy Res
, vol.118
, pp. 22-28
-
-
Schoeler, N.E.1
Leu, C.2
White, J.3
-
10
-
-
84924356420
-
The ketone metabolite b-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease
-
Youm YH, Nguyen KY, Grant RW, et al. The ketone metabolite b-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease. Nat Med 2015; 21:263-269.
-
(2015)
Nat Med
, vol.21
, pp. 263-269
-
-
Youm, Y.H.1
Nguyen, K.Y.2
Grant, R.W.3
-
11
-
-
84901325457
-
The b-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages
-
Rahman M, Muhammad S, Khan MA, et al. The b-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages. Nat Commun 2014; 5:3944.
-
(2014)
Nat Commun
, vol.5
, pp. 3944
-
-
Rahman, M.1
Muhammad, S.2
Khan, M.A.3
-
12
-
-
84939190356
-
Ketone bodies effectively compete with glucose for neuronal acetyl-CoA generation in rat hippocampal slices
-
Valente-Silva P, Lemos C, Kofalvi A, et al. Ketone bodies effectively compete with glucose for neuronal acetyl-CoA generation in rat hippocampal slices. NMR Biomed 2015; 28:1111-1116.
-
(2015)
NMR Biomed
, vol.28
, pp. 1111-1116
-
-
Valente-Silva, P.1
Lemos, C.2
Kofalvi, A.3
-
13
-
-
84921472344
-
Decreased carbon shunting from glucose toward oxidative metabolism in diet-induced ketotic rat brain
-
Zhang Y, Zhang S, Marin-Valencia I, Puchowicz MA. Decreased carbon shunting from glucose toward oxidative metabolism in diet-induced ketotic rat brain. J Neurochem 2015; 132:301-312.
-
(2015)
J Neurochem
, vol.132
, pp. 301-312
-
-
Zhang, Y.1
Zhang, S.2
Marin-Valencia, I.3
Puchowicz, M.A.4
-
14
-
-
84964305217
-
Valproate effect on ketosis in children under ketogenic diet
-
Spilioti M, Pavlou E, Gogou M, et al. Valproate effect on ketosis in children under ketogenic diet. Eur J Paediatr Neurol 2016; 20:555-559.
-
(2016)
Eur J Paediatr Neurol
, vol.20
, pp. 555-559
-
-
Spilioti, M.1
Pavlou, E.2
Gogou, M.3
-
15
-
-
84958741342
-
B-Hydroxybutyrate supports synaptic vesicle cycling but reduces endocytosis and exocytosis in rat brain synaptosomes
-
Hrynevich SV, Waseem TV, Hebert A, et al. b-Hydroxybutyrate supports synaptic vesicle cycling but reduces endocytosis and exocytosis in rat brain synaptosomes. Neurochem Int 2016; 93:73-81.
-
(2016)
Neurochem Int
, vol.93
, pp. 73-81
-
-
Hrynevich, S.V.1
Waseem, T.V.2
Hebert, A.3
-
16
-
-
84938099390
-
Anticonvulsant properties of an oral ketone ester in a pentylenetetrazole-model of seizure
-
Viggiano A, Pilla R, Arnold P, et al. Anticonvulsant properties of an oral ketone ester in a pentylenetetrazole-model of seizure. Brain Res 2015; 1618:50-54.
-
(2015)
Brain Res
, vol.1618
, pp. 50-54
-
-
Viggiano, A.1
Pilla, R.2
Arnold, P.3
-
17
-
-
84983777921
-
Ketone ester supplementation attenuates seizure activity, and improves behavior and hippocampal synaptic plasticity in an Angelman syndrome mouse model
-
Ciarlone SL, Grieco JC, D'Agostino DP, Weeber EJ. Ketone ester supplementation attenuates seizure activity, and improves behavior and hippocampal synaptic plasticity in an Angelman syndrome mouse model. Neurobiol Dis 2016; 96:38-46.
-
(2016)
Neurobiol Dis
, vol.96
, pp. 38-46
-
-
Ciarlone, S.L.1
Grieco, J.C.2
D'Agostino, D.P.3
Weeber, E.J.4
-
18
-
-
84875235362
-
Seizure control by ketogenic dietassociated medium chain fatty acids
-
Chang P, Terbach N, Plant N, et al. Seizure control by ketogenic dietassociated medium chain fatty acids. Neuropharmacology 2013; 69:105-114.
-
(2013)
Neuropharmacology
, vol.69
, pp. 105-114
-
-
Chang, P.1
Terbach, N.2
Plant, N.3
-
19
-
-
84873411637
-
Heptanoate as a neural fuel: Energetic and neurotransmitter precursors in normal and glucose transporter I-deficient (G1D) brain
-
Marin-Valencia I, Good LB, Ma Q, et al. Heptanoate as a neural fuel: energetic and neurotransmitter precursors in normal and glucose transporter I-deficient (G1D) brain. J Cereb Blood Flow Metab 2013; 33:175-182.
-
(2013)
J Cereb Blood Flow Metab
, vol.33
, pp. 175-182
-
-
Marin-Valencia, I.1
Good, L.B.2
Ma, Q.3
-
20
-
-
84908007846
-
Triheptanoin for glucose transporter type i deficiency (G1D): Modulation of human ictogenesis, cerebral metabolic rate, and cognitive indices by a food supplement
-
Pascual JM, Liu P, Mao D, et al. Triheptanoin for glucose transporter type I deficiency (G1D): modulation of human ictogenesis, cerebral metabolic rate, and cognitive indices by a food supplement. JAMA Neurol 2014; 71:1255-1265.
-
(2014)
JAMA Neurol
, vol.71
, pp. 1255-1265
-
-
Pascual, J.M.1
Liu, P.2
Mao, D.3
-
21
-
-
84919762194
-
Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency
-
Chang P, Zuckermann AM, Williams S, et al. Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency. J Pharmacol Exp Ther 2015; 352:43-52.
-
(2015)
J Pharmacol Exp Ther
, vol.352
, pp. 43-52
-
-
Chang, P.1
Zuckermann, A.M.2
Williams, S.3
-
22
-
-
85014644089
-
Tridecanoin is anticonvulsant, antioxidant, and improves mitochondrial function
-
[Epub ahead of print]
-
Tan KN, Carrasco-Pozo C, McDonald TS, et al. Tridecanoin is anticonvulsant, antioxidant, and improves mitochondrial function. J Cereb Blood Flow Metab 2016. [Epub ahead of print]
-
(2016)
J Cereb Blood Flow Metab
-
-
Tan, K.N.1
Carrasco-Pozo, C.2
McDonald, T.S.3
-
23
-
-
84963765159
-
The pleiotropic effects of decanoic acid treatment on mitochondrial function in fibroblasts from patients with complex i deficient Leigh syndrome
-
Kanabus M, Fassone E, Hughes SD, et al. The pleiotropic effects of decanoic acid treatment on mitochondrial function in fibroblasts from patients with complex I deficient Leigh syndrome. J Inherit Metab Dis 2016; 39:415-426.
-
(2016)
J Inherit Metab Dis
, vol.39
, pp. 415-426
-
-
Kanabus, M.1
Fassone, E.2
Hughes, S.D.3
-
24
-
-
84899410824
-
The ketogenic diet component decanoic acid increases mitochondrial citrate synthase and complex i activity in neuronal cells
-
Hughes SD, Kanabus M, Anderson G, et al. The ketogenic diet component decanoic acid increases mitochondrial citrate synthase and complex I activity in neuronal cells. J Neurochem 2014; 129:426-433.
-
(2014)
J Neurochem
, vol.129
, pp. 426-433
-
-
Hughes, S.D.1
Kanabus, M.2
Anderson, G.3
-
25
-
-
84966372836
-
Medium-chain fatty acids inhibit mitochondrial metabolism in astrocytes promoting astrocyte-neuron lactate and ketone body shuttle systems
-
Thevenet J, De Marchi U, Domingo JS, et al. Medium-chain fatty acids inhibit mitochondrial metabolism in astrocytes promoting astrocyte-neuron lactate and ketone body shuttle systems. FASEB J 2016; 30:1913-1926.
-
(2016)
FASEB J
, vol.30
, pp. 1913-1926
-
-
Thevenet, J.1
De Marchi, U.2
Domingo, J.S.3
-
26
-
-
84949255141
-
Is the interaction between fatty acids and tryptophan responsible for the efficacy of a ketogenic diet in epilepsy? the new hypothesis of action
-
Maciejak P, Szyndler J, Turzynska D, et al. Is the interaction between fatty acids and tryptophan responsible for the efficacy of a ketogenic diet in epilepsy? The new hypothesis of action. Neuroscience 2016; 313:130-148.
-
(2016)
Neuroscience
, vol.313
, pp. 130-148
-
-
Maciejak, P.1
Szyndler, J.2
Turzynska, D.3
-
27
-
-
84977079443
-
Seizure control by decanoic acid through direct AMPA receptor inhibition
-
Chang P, Augustin K, Boddum K, et al. Seizure control by decanoic acid through direct AMPA receptor inhibition. Brain 2016; 139:431-443.
-
(2016)
Brain
, vol.139
, pp. 431-443
-
-
Chang, P.1
Augustin, K.2
Boddum, K.3
-
28
-
-
84956717094
-
The molecular basis of polyunsaturated fatty acid interactions with the shaker voltage-gated potassium channel
-
Yazdi S, Stein M, Elinder F, et al. The molecular basis of polyunsaturated fatty acid interactions with the shaker voltage-gated potassium channel. PLoS Comput Biol 2016; 12:e1004704.
-
(2016)
PLoS Comput Biol
, vol.12
, pp. e1004704
-
-
Yazdi, S.1
Stein, M.2
Elinder, F.3
-
29
-
-
85015852174
-
Ketogenic diet, but not polyunsaturated fatty acid diet, reduces spontaneous seizures in juvenile rats with kainic acid-induced epilepsy
-
Dustin SM, Stafstrom CE. Ketogenic diet, but not polyunsaturated fatty acid diet, reduces spontaneous seizures in juvenile rats with kainic acid-induced epilepsy. J Epilepsy Res 2016; 6:1-7.
-
(2016)
J Epilepsy Res
, vol.6
, pp. 1-7
-
-
Dustin, S.M.1
Stafstrom, C.E.2
-
31
-
-
84908158825
-
Hepatic IRE1a regulates fasting-induced metabolic adaptive programs through the XBP1s-PPARalpha axis signalling
-
Shao M, Shan B, Liu Y, et al. Hepatic IRE1a regulates fasting-induced metabolic adaptive programs through the XBP1s-PPARalpha axis signalling. Nat Commun 2014; 5:3528.
-
(2014)
Nat Commun
, vol.5
, pp. 3528
-
-
Shao, M.1
Shan, B.2
Liu, Y.3
-
32
-
-
84901322478
-
In vivo ketogenic diet treatment attenuates pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices from epileptic Kv 1.1a knockout mice
-
Simeone TA, Samson KK, Matthews SA, Simeone KA. In vivo ketogenic diet treatment attenuates pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices from epileptic Kv 1.1a knockout mice. Epilepsia 2014; 55:e44-e49.
-
(2014)
Epilepsia
, vol.55
, pp. e44-e49
-
-
Simeone, T.A.1
Samson, K.K.2
Matthews, S.A.3
Simeone, K.A.4
-
33
-
-
84995394885
-
Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy
-
Simeone TA, Matthews SA, Samson KK, Simeone KA. Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy. Exp Neurol 2017; 287:54-64.
-
(2017)
Exp Neurol
, vol.287
, pp. 54-64
-
-
Simeone, T.A.1
Matthews, S.A.2
Samson, K.K.3
Simeone, K.A.4
-
34
-
-
84861440823
-
BAD-dependent regulation of fuel metabolism and K(ATP) channel activity confers resistance to epileptic seizures
-
Gimenez-Cassina A, Martinez-Francois JR, Fisher JK, et al. BAD-dependent regulation of fuel metabolism and K(ATP) channel activity confers resistance to epileptic seizures. Neuron 2012; 74:719-730.
-
(2012)
Neuron
, vol.74
, pp. 719-730
-
-
Gimenez-Cassina, A.1
Martinez-Francois, J.R.2
Fisher, J.K.3
-
35
-
-
84929991757
-
Ketones prevent oxidative impairment of hippocampal synaptic integrity through KATP channels
-
Kim DY, Abdelwahab MG, Lee SH, et al. Ketones prevent oxidative impairment of hippocampal synaptic integrity through KATP channels. PLoS One 2015; 10:e0119316.
-
(2015)
PLoS One
, vol.10
, pp. e0119316
-
-
Kim, D.Y.1
Abdelwahab, M.G.2
Lee, S.H.3
-
36
-
-
84914706500
-
Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels
-
Lutas A, Birnbaumer L, YellenG.Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels. J Neurosci 2014; 34:16336-16347.
-
(2014)
J Neurosci
, vol.34
, pp. 16336-16347
-
-
Lutas, A.1
Birnbaumer, L.2
Yellen, G.3
-
37
-
-
84964587682
-
Effect of dietary fat and the circadian clock on the expression of brain-derived neurotrophic factor (BDNF)
-
Genzer Y, Dadon M, Burg C, et al. Effect of dietary fat and the circadian clock on the expression of brain-derived neurotrophic factor (BDNF). Mol Cell Endocrinol 2016; 430:49-55.
-
(2016)
Mol Cell Endocrinol
, vol.430
, pp. 49-55
-
-
Genzer, Y.1
Dadon, M.2
Burg, C.3
-
38
-
-
84876786978
-
Brain changes in BDNF and S100B induced by ketogenic diets in Wistar rats
-
Vizuete AF, de Souza DF, Guerra MC, et al. Brain changes in BDNF and S100B induced by ketogenic diets in Wistar rats. Life Sci 2013; 92:923-928.
-
(2013)
Life Sci
, vol.92
, pp. 923-928
-
-
Vizuete, A.F.1
De Souza, D.F.2
Guerra, M.C.3
-
39
-
-
84946475986
-
The ketogenic diet compensates for AGC1 deficiency and improves myelination
-
Dahlin M, Martin DA, Hedlund Z, et al. The ketogenic diet compensates for AGC1 deficiency and improves myelination. Epilepsia 2015; 56:e176-e181.
-
(2015)
Epilepsia
, vol.56
, pp. e176-e181
-
-
Dahlin, M.1
Martin, D.A.2
Hedlund, Z.3
-
40
-
-
85002714982
-
Altered glycolysis and mitochondrial respiration in a zebrafish model of Dravet syndrome
-
ENEURO.0008-16.2016
-
Kumar MG, Rowley S, Fulton R, et al. Altered glycolysis and mitochondrial respiration in a zebrafish model of Dravet syndrome. eNeuro 2016; 3. (2):ENEURO.0008-16.2016.
-
(2016)
ENeuro
, vol.3
, Issue.2
-
-
Kumar, M.G.1
Rowley, S.2
Fulton, R.3
-
41
-
-
84933181448
-
Ketone bodies mediate antiseizure effects through mitochondrial permeability transition
-
Kim DY, Simeone KA, Simeone TA, et al. Ketone bodies mediate antiseizure effects through mitochondrial permeability transition. Ann Neurol 2015; 78:77-87.
-
(2015)
Ann Neurol
, vol.78
, pp. 77-87
-
-
Kim, D.Y.1
Simeone, K.A.2
Simeone, T.A.3
-
42
-
-
84911059062
-
Catabolism of (2E)-4-hydroxy-2-nonenal via v-and v-1-oxidation stimulated by ketogenic diet
-
Jin Z, Berthiaume JM, Li Q, et al. Catabolism of (2E)-4-hydroxy-2-nonenal via v-and v-1-oxidation stimulated by ketogenic diet. J Biol Chem 2014; 289:32327-32338.
-
(2014)
J Biol Chem
, vol.289
, pp. 32327-32338
-
-
Jin, Z.1
Berthiaume, J.M.2
Li, Q.3
-
43
-
-
84907015381
-
FGF21 is an endocrine signal of protein restriction
-
Laeger T, Henagan TM, Albarado DC, et al. FGF21 is an endocrine signal of protein restriction. J Clin Invest 2014; 124:3913-3922.
-
(2014)
J Clin Invest
, vol.124
, pp. 3913-3922
-
-
Laeger, T.1
Henagan, T.M.2
Albarado, D.C.3
-
44
-
-
84925334416
-
Epilepsy treatment. Targeting LDH enzymes with a stiripentol analog to treat epilepsy
-
Sada N, Lee S, Katsu T, et al. Epilepsy treatment. Targeting LDH enzymes with a stiripentol analog to treat epilepsy. Science 2015; 347:1362-1367.
-
(2015)
Science
, vol.347
, pp. 1362-1367
-
-
Sada, N.1
Lee, S.2
Katsu, T.3
-
45
-
-
84984984358
-
Ketogenic diet treatment increases longevity in Kcna1-null mice, a model of sudden unexpected death in epilepsy
-
Simeone KA, Matthews SA, Rho JM, Simeone TA. Ketogenic diet treatment increases longevity in Kcna1-null mice, a model of sudden unexpected death in epilepsy. Epilepsia 2016; 57:e178-e182.
-
(2016)
Epilepsia
, vol.57
, pp. e178-e182
-
-
Simeone, K.A.1
Matthews, S.A.2
Rho, J.M.3
Simeone, T.A.4
-
46
-
-
84888168918
-
Deep sequencing reveals increased DNA methylation in chronic rat epilepsy
-
Kobow K, Kaspi A, Harikrishnan KN, et al. Deep sequencing reveals increased DNA methylation in chronic rat epilepsy. Acta Neuropathol 2013; 126:741-756.
-
(2013)
Acta Neuropathol
, vol.126
, pp. 741-756
-
-
Kobow, K.1
Kaspi, A.2
Harikrishnan, K.N.3
-
47
-
-
84940021980
-
Ketogenic diet prevents epileptogenesis and disease progression in adult mice and rats
-
Lusardi TA, Akula KK, Coffman SQ, et al. Ketogenic diet prevents epileptogenesis and disease progression in adult mice and rats. Neuropharmacology 2015; 99:500-509.
-
(2015)
Neuropharmacology
, vol.99
, pp. 500-509
-
-
Lusardi, T.A.1
Akula, K.K.2
Coffman, S.Q.3
-
48
-
-
79959957820
-
A ketogenic diet suppresses seizures in mice through adenosine A1 receptors
-
Masino SA, Li T, Theofilas P, et al. A ketogenic diet suppresses seizures in mice through adenosine A1 receptors. J Clin Inv 2011; 121:2679-2683.
-
(2011)
J Clin Inv
, vol.121
, pp. 2679-2683
-
-
Masino, S.A.1
Li, T.2
Theofilas, P.3
-
49
-
-
84879710932
-
Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis
-
Williams-Karnesky RL, Sandau US, Lusardi TA, et al. Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis. J Clin Inv 2013; 123:3552-3563.
-
(2013)
J Clin Inv
, vol.123
, pp. 3552-3563
-
-
Williams-Karnesky, R.L.1
Sandau, U.S.2
Lusardi, T.A.3
-
50
-
-
84987629405
-
Ketogenic diet modifies the gut microbiota in a murine model of autism spectrum disorder
-
Newell C, Bomhof MR, Reimer RA, et al. Ketogenic diet modifies the gut microbiota in a murine model of autism spectrum disorder. Mol Autism 2016; 7:37.
-
(2016)
Mol Autism
, vol.7
, pp. 37
-
-
Newell, C.1
Bomhof, M.R.2
Reimer, R.A.3
|