Lasalocid induces cytotoxic apoptosis and cytoprotective autophagy through reactive oxygen species in human prostate cancer PC-3 cells

Biomedicine and Pharmacotherapy

Volumn 88, Issue , 2017, Pages 1016-1024

  Kim, Kwang Youn ^a   Kim, Sang Hun ^b   Yu, Sun Nyoung ^b   Park, Sul Gi ^b   Kim, Young Wook ^b   Nam, Hyo Won ^b   An, Hyun Hee ^b   Yu, Hak Sun ^b,e   Kim, Young Woo ^a   Ji, Jae Hoon ^c   Seo, Young Kyo ^d   Ahn, Soon Cheol ^b,e  

^a Daegu Haany University   (South Korea)

^b Pusan National University School of Medicine   (South Korea)

^c Ajou University School of Medicine   (South Korea)

^d Ulsan National Institute of Science and Technology   (South Korea)

^e Pusan National University   (South Korea)

Author keywords

Apoptosis; Autophagy; Cell cycle arrest; Lasalocid; Prostate cancer; Reactive oxygen species

Indexed keywords

3 METHYLADENINE; CASPASE 3; LASALOCID; MICROTUBULE ASSOCIATED PROTEIN 1; N(G) NITROARGININE METHYL ESTER; PROCASPASE 3; REACTIVE OXYGEN METABOLITE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; CELL PROLIFERATION; DRUG EFFECTS; MALE; METABOLISM; PATHOLOGY; PROSTATE TUMOR; TUMOR CELL LINE;

APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; CELL PROLIFERATION; G1 PHASE CELL CYCLE CHECKPOINTS; HUMANS; LASALOCID; MALE; PROSTATIC NEOPLASMS; REACTIVE OXYGEN SPECIES;

EID: 85011580169     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2017.01.140     Document Type: Article

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