메뉴 건너뛰기




Volumn 82, Issue 2, 2017, Pages 127-138

Sex-Specific Neurodevelopmental Programming by Placental Insulin Receptors on Stress Reactivity and Sensorimotor Gating

Author keywords

Epigenetic; Insulin; Prefrontal cortex; Prenatal; Serotonin; Sex

Indexed keywords

CYTOCHROME C OXIDASE; INSULIN RECEPTOR; SEROTONIN; TRANSCRIPTOME;

EID: 85011339652     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2016.12.025     Document Type: Article
Times cited : (36)

References (92)
  • 1
    • 84941670933 scopus 로고    scopus 로고
    • Maternal obesity, overweight and gestational diabetes affect the offspring neurodevelopment at 6 and 18 months of age—A follow-up from the PREOBE cohort
    • Torres-Espinola, F.J., Berglund, S.K., García-Valdés, L.M., Segura, M.T., Jerez, A., Campos, D., et al. Maternal obesity, overweight and gestational diabetes affect the offspring neurodevelopment at 6 and 18 months of age—A follow-up from the PREOBE cohort. PLoS One, 10, 2015, e0133010.
    • (2015) PLoS One , vol.10 , pp. e0133010
    • Torres-Espinola, F.J.1    Berglund, S.K.2    García-Valdés, L.M.3    Segura, M.T.4    Jerez, A.5    Campos, D.6
  • 2
    • 0035019549 scopus 로고    scopus 로고
    • School-age children born to diabetic mothers and to mothers with gestational diabetes exhibit a high rate of inattention and fine and gross motor impairment
    • Ornoy, A., Ratzon, N., Greenbaum, C., Wolf, A., Dulitzky, M., School-age children born to diabetic mothers and to mothers with gestational diabetes exhibit a high rate of inattention and fine and gross motor impairment. J Pediatr Endocrinol Metab 14:Suppl 1 (2001), 681–689.
    • (2001) J Pediatr Endocrinol Metab , vol.14 , pp. 681-689
    • Ornoy, A.1    Ratzon, N.2    Greenbaum, C.3    Wolf, A.4    Dulitzky, M.5
  • 3
    • 32244446763 scopus 로고    scopus 로고
    • Growth and neurodevelopmental outcome of children born to mothers with pregestational and gestational diabetes
    • Ornoy, A., Growth and neurodevelopmental outcome of children born to mothers with pregestational and gestational diabetes. Pediatr Endocrinol Rev 3 (2005), 104–113.
    • (2005) Pediatr Endocrinol Rev , vol.3 , pp. 104-113
    • Ornoy, A.1
  • 4
    • 53349142647 scopus 로고    scopus 로고
    • Diabetes mellitus during pregnancy and increased risk of schizophrenia in offspring: A review of the evidence and putative mechanisms
    • Van Lieshout, R.J., Voruganti, L.P., Diabetes mellitus during pregnancy and increased risk of schizophrenia in offspring: A review of the evidence and putative mechanisms. J Psychiatry Neurosci 33 (2008), 395–404.
    • (2008) J Psychiatry Neurosci , vol.33 , pp. 395-404
    • Van Lieshout, R.J.1    Voruganti, L.P.2
  • 5
    • 84929493980 scopus 로고    scopus 로고
    • Maternal prepregnancy body mass index and child psychosocial development at 6 years of age
    • Jo, H., Schieve, L.A., Sharma, A.J., Hinkle, S.N., Li, R., Lind, J.N., Maternal prepregnancy body mass index and child psychosocial development at 6 years of age. Pediatrics 135 (2015), e1198–e1209.
    • (2015) Pediatrics , vol.135 , pp. e1198-e1209
    • Jo, H.1    Schieve, L.A.2    Sharma, A.J.3    Hinkle, S.N.4    Li, R.5    Lind, J.N.6
  • 6
    • 0028360323 scopus 로고
    • Long-term developmental follow-up of infants of diabetic mothers
    • Sells, C.J., Robinson, N.M., Brown, Z., Knopp, R.H., Long-term developmental follow-up of infants of diabetic mothers. J Pediatr 125 (1994), S9–S17.
    • (1994) J Pediatr , vol.125 , pp. S9-S17
    • Sells, C.J.1    Robinson, N.M.2    Brown, Z.3    Knopp, R.H.4
  • 7
    • 84860888269 scopus 로고    scopus 로고
    • Does maternal body mass index during pregnancy influence risk of schizophrenia in the adult offspring?
    • Khandaker, G.M., Dibben, C.R.M., Jones, P.B., Does maternal body mass index during pregnancy influence risk of schizophrenia in the adult offspring?. Obes Rev 13 (2012), 518–527.
    • (2012) Obes Rev , vol.13 , pp. 518-527
    • Khandaker, G.M.1    Dibben, C.R.M.2    Jones, P.B.3
  • 8
    • 84930647519 scopus 로고    scopus 로고
    • The role of maternal obesity in the risk of neuropsychiatric disorders
    • Rivera, H.M., Christiansen, K.J., Sullivan, E.L., The role of maternal obesity in the risk of neuropsychiatric disorders. Front Neurosci, 9, 2015, 194.
    • (2015) Front Neurosci , vol.9 , pp. 194
    • Rivera, H.M.1    Christiansen, K.J.2    Sullivan, E.L.3
  • 9
    • 77649188000 scopus 로고    scopus 로고
    • Obesity in pregnancy: Prevalence and metabolic consequences
    • Huda, S.S., Brodie, L.E., Sattar, N., Obesity in pregnancy: Prevalence and metabolic consequences. Semin Fetal Neonatal Med 15 (2010), 70–76.
    • (2010) Semin Fetal Neonatal Med , vol.15 , pp. 70-76
    • Huda, S.S.1    Brodie, L.E.2    Sattar, N.3
  • 10
    • 34250011188 scopus 로고    scopus 로고
    • The increasing prevalence of diabetes in pregnancy
    • Hunt, K.J., Schuller, K.L., The increasing prevalence of diabetes in pregnancy. Obstet Gynecol Clin North Am 34 (2007), 173–199.
    • (2007) Obstet Gynecol Clin North Am , vol.34 , pp. 173-199
    • Hunt, K.J.1    Schuller, K.L.2
  • 11
    • 84911461625 scopus 로고    scopus 로고
    • Prevalence estimates of gestational diabetes mellitus in the United States: Pregnancy Risk Assessment Monitoring System (PRAMS), 2007–2010
    • DeSisto, C.L., Kim, S.Y., Sharma, A.J., Prevalence estimates of gestational diabetes mellitus in the United States: Pregnancy Risk Assessment Monitoring System (PRAMS), 2007–2010. Prev Chronic Dis, 11, 2014, E104.
    • (2014) Prev Chronic Dis , vol.11 , pp. E104
    • DeSisto, C.L.1    Kim, S.Y.2    Sharma, A.J.3
  • 12
    • 84858048546 scopus 로고    scopus 로고
    • Summary health statistics for U.S. children: National Health Interview Survey, 2010
    • Bloom, B., Cohen, R.A., Freeman, G., Summary health statistics for U.S. children: National Health Interview Survey, 2010. Vital Health Stat 10, 2011, 1–80.
    • (2011) Vital Health Stat 10 , pp. 1-80
    • Bloom, B.1    Cohen, R.A.2    Freeman, G.3
  • 13
    • 85033345484 scopus 로고    scopus 로고
    • Autism and Developmental Disabilities Monitoring Network Surveillance Year 2010 Principal Investigators. Prevalence of autism spectrum disorder among children aged 8 years—Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2010. Available at: Accessed May 10.
    • Autism and Developmental Disabilities Monitoring Network Surveillance Year 2010 Principal Investigators. Prevalence of autism spectrum disorder among children aged 8 years—Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2010. Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/ss6302a1.htm. Accessed May 10, 2016.
    • (2016)
  • 14
    • 77957753702 scopus 로고    scopus 로고
    • Maternal high fat feeding and gestational dietary restriction: Effects on offspring body weight, food intake and hypothalamic gene expression over three generations in mice
    • Giraudo, S.Q., Della-Fera, M.A., Proctor, L., Wickwire, K., Ambati, S., Baile, C.A., Maternal high fat feeding and gestational dietary restriction: Effects on offspring body weight, food intake and hypothalamic gene expression over three generations in mice. Pharmacol Biochem Behav 97 (2010), 121–129.
    • (2010) Pharmacol Biochem Behav , vol.97 , pp. 121-129
    • Giraudo, S.Q.1    Della-Fera, M.A.2    Proctor, L.3    Wickwire, K.4    Ambati, S.5    Baile, C.A.6
  • 15
    • 84904439239 scopus 로고    scopus 로고
    • Sex differences in LXR expression in normal offspring and in rats born to diabetic dams
    • Kruse, M.S., Vega, M.C., Rey, M., Coirini, H., Sex differences in LXR expression in normal offspring and in rats born to diabetic dams. J Endocrinol 222 (2014), 53–60.
    • (2014) J Endocrinol , vol.222 , pp. 53-60
    • Kruse, M.S.1    Vega, M.C.2    Rey, M.3    Coirini, H.4
  • 16
    • 84890879744 scopus 로고    scopus 로고
    • Peri-conceptional obesogenic exposure induces sex-specific programming of disease susceptibilities in adult mouse offspring
    • Dahlhoff, M., Pfister, S., Blutke, A., Rozman, J., Klingenspor, M., Deutsch, M.J., et al. Peri-conceptional obesogenic exposure induces sex-specific programming of disease susceptibilities in adult mouse offspring. Biochim Biophys Acta 1842 (2014), 304–317.
    • (2014) Biochim Biophys Acta , vol.1842 , pp. 304-317
    • Dahlhoff, M.1    Pfister, S.2    Blutke, A.3    Rozman, J.4    Klingenspor, M.5    Deutsch, M.J.6
  • 17
    • 84900560787 scopus 로고    scopus 로고
    • Maternal high-fat diet induces insulin resistance and deterioration of pancreatic β-cell function in adult offspring with sex differences in mice
    • Yokomizo, H., Inoguchi, T., Sonoda, N., Sakaki, Y., Maeda, Y., Inoue, T., et al. Maternal high-fat diet induces insulin resistance and deterioration of pancreatic β-cell function in adult offspring with sex differences in mice. Am J Physiol Endocrinol Metab 306 (2014), E1163–E1175.
    • (2014) Am J Physiol Endocrinol Metab , vol.306 , pp. E1163-E1175
    • Yokomizo, H.1    Inoguchi, T.2    Sonoda, N.3    Sakaki, Y.4    Maeda, Y.5    Inoue, T.6
  • 18
    • 84884210057 scopus 로고    scopus 로고
    • Sexual dimorphism in fat distribution and metabolic profile in mice offspring from diet-induced obese mothers
    • Ornellas, F., Mello, V.S., Mandarim-de-Lacerda, C.A., Aguila, M.B., Sexual dimorphism in fat distribution and metabolic profile in mice offspring from diet-induced obese mothers. Life Sci 93 (2013), 454–463.
    • (2013) Life Sci , vol.93 , pp. 454-463
    • Ornellas, F.1    Mello, V.S.2    Mandarim-de-Lacerda, C.A.3    Aguila, M.B.4
  • 19
    • 84929203519 scopus 로고    scopus 로고
    • Gestational diabetes alters offspring DNA methylation profiles in human and rat: Identification of key pathways involved in endocrine system disorders, insulin signaling, diabetes signaling, and ILK signaling
    • Petropoulos, S., Guillemin, C., Ergaz, Z., Dimov, S., Suderman, M., Weinstein-Fudim, L., et al. Gestational diabetes alters offspring DNA methylation profiles in human and rat: Identification of key pathways involved in endocrine system disorders, insulin signaling, diabetes signaling, and ILK signaling. Endocrinology 156 (2015), 2222–2238.
    • (2015) Endocrinology , vol.156 , pp. 2222-2238
    • Petropoulos, S.1    Guillemin, C.2    Ergaz, Z.3    Dimov, S.4    Suderman, M.5    Weinstein-Fudim, L.6
  • 20
    • 84924587656 scopus 로고    scopus 로고
    • GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake
    • Li, Y., Hadden, C., Singh, P., Mercado, C.P., Murphy, P., Dajani, N.K., et al. GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake. Proc Natl Acad Sci U S A 111 (2014), E5697–E5705.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. E5697-E5705
    • Li, Y.1    Hadden, C.2    Singh, P.3    Mercado, C.P.4    Murphy, P.5    Dajani, N.K.6
  • 21
    • 84994242506 scopus 로고    scopus 로고
    • Discrepancy in insulin regulation between GDM-platelets and -placenta
    • Li, Y., Cooper, A., Odibo, I.N., Ahmed, A., Murphy, P., Koonce, R., et al. Discrepancy in insulin regulation between GDM-platelets and -placenta. J Biol Chem 291 (2016), 9657–9665.
    • (2016) J Biol Chem , vol.291 , pp. 9657-9665
    • Li, Y.1    Cooper, A.2    Odibo, I.N.3    Ahmed, A.4    Murphy, P.5    Koonce, R.6
  • 22
    • 64549160282 scopus 로고    scopus 로고
    • Defective insulin signaling in placenta from pregnancies complicated by gestational diabetes mellitus
    • Colomiere, M., Permezel, M., Riley, C., Desoye, G., Lappas, M., Defective insulin signaling in placenta from pregnancies complicated by gestational diabetes mellitus. Eur J Endocrinol 160 (2009), 567–578.
    • (2009) Eur J Endocrinol , vol.160 , pp. 567-578
    • Colomiere, M.1    Permezel, M.2    Riley, C.3    Desoye, G.4    Lappas, M.5
  • 23
    • 0026528844 scopus 로고
    • Insulin binding to trophoblast plasma membranes and placental glycogen content in well-controlled gestational diabetic women treated with diet or insulin, in well-controlled overt diabetic patients and in healthy control subjects
    • Desoye, G., Hofmann, H.H., Weiss, P.A., Insulin binding to trophoblast plasma membranes and placental glycogen content in well-controlled gestational diabetic women treated with diet or insulin, in well-controlled overt diabetic patients and in healthy control subjects. Diabetologia 35 (1992), 45–55.
    • (1992) Diabetologia , vol.35 , pp. 45-55
    • Desoye, G.1    Hofmann, H.H.2    Weiss, P.A.3
  • 25
    • 78751512142 scopus 로고    scopus 로고
    • Impairment of insulin receptor signal transduction in placentas of intra-uterine growth-restricted newborns and its relationship with fetal growth
    • Street, M.E., Viani, I., Ziveri, M.A., Volta, C., Smerieri, A., Bernasconi, S., Impairment of insulin receptor signal transduction in placentas of intra-uterine growth-restricted newborns and its relationship with fetal growth. Eur J Endocrinol 164 (2011), 45–52.
    • (2011) Eur J Endocrinol , vol.164 , pp. 45-52
    • Street, M.E.1    Viani, I.2    Ziveri, M.A.3    Volta, C.4    Smerieri, A.5    Bernasconi, S.6
  • 26
    • 36048965154 scopus 로고    scopus 로고
    • Preeclampsia, insulin signalling and immunological dysfunction: A fetal, maternal or placental disorder?
    • Rademacher, T.W., Gumaa, K., Scioscia, M., Preeclampsia, insulin signalling and immunological dysfunction: A fetal, maternal or placental disorder?. J Reprod Immunol 76 (2007), 78–84.
    • (2007) J Reprod Immunol , vol.76 , pp. 78-84
    • Rademacher, T.W.1    Gumaa, K.2    Scioscia, M.3
  • 27
    • 32544441869 scopus 로고    scopus 로고
    • Insulin resistance in human preeclamptic placenta is mediated by serine phosphorylation of insulin receptor substrate-1 and -2
    • Scioscia, M., Gumaa, K., Kunjara, S., Paine, M.A., Selvaggi, L.E., Rodeck, C.H., Rademacher, T.W., Insulin resistance in human preeclamptic placenta is mediated by serine phosphorylation of insulin receptor substrate-1 and -2. J Clin Endocrinol Metab 91 (2006), 709–717.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 709-717
    • Scioscia, M.1    Gumaa, K.2    Kunjara, S.3    Paine, M.A.4    Selvaggi, L.E.5    Rodeck, C.H.6    Rademacher, T.W.7
  • 28
    • 84949543815 scopus 로고    scopus 로고
    • The placenta as a mediator of stress effects on neurodevelopmental reprogramming
    • Bronson, S.L., Bale, T.L., The placenta as a mediator of stress effects on neurodevelopmental reprogramming. Neuropsychopharmacology 41 (2016), 207–218.
    • (2016) Neuropsychopharmacology , vol.41 , pp. 207-218
    • Bronson, S.L.1    Bale, T.L.2
  • 29
    • 33645306841 scopus 로고    scopus 로고
    • Placental adaptive responses and fetal programming
    • Myatt, L., Placental adaptive responses and fetal programming. J Physiol 572 (2006), 25–30.
    • (2006) J Physiol , vol.572 , pp. 25-30
    • Myatt, L.1
  • 30
    • 20444430424 scopus 로고    scopus 로고
    • Development of structures and transport functions in the mouse placenta
    • Watson, E.D., Cross, J.C., Development of structures and transport functions in the mouse placenta. Physiology (Bethesda) 20 (2005), 180–193.
    • (2005) Physiology (Bethesda) , vol.20 , pp. 180-193
    • Watson, E.D.1    Cross, J.C.2
  • 31
    • 34250902914 scopus 로고    scopus 로고
    • Role of the placenta in fetal programming: Underlying mechanisms and potential interventional approaches
    • Jansson, T., Powell, T.L., Role of the placenta in fetal programming: Underlying mechanisms and potential interventional approaches. Clin Sci (Lond) 113 (2007), 1–13.
    • (2007) Clin Sci (Lond) , vol.113 , pp. 1-13
    • Jansson, T.1    Powell, T.L.2
  • 33
    • 0028181069 scopus 로고
    • Insulin receptors in syncytiotrophoblast and fetal endothelium of human placenta: Immunohistochemical evidence for developmental changes in distribution pattern
    • Desoye, G., Hartmann, M., Blaschitz, A., Dohr, G., Hahn, T., Kohnen, G., Kaufmann, P., Insulin receptors in syncytiotrophoblast and fetal endothelium of human placenta: Immunohistochemical evidence for developmental changes in distribution pattern. Histochemistry 101 (1994), 277–285.
    • (1994) Histochemistry , vol.101 , pp. 277-285
    • Desoye, G.1    Hartmann, M.2    Blaschitz, A.3    Dohr, G.4    Hahn, T.5    Kohnen, G.6    Kaufmann, P.7
  • 34
    • 31444436853 scopus 로고    scopus 로고
    • Insulin control of placental gene expression shifts from mother to foetus over the course of pregnancy
    • Hiden, U., Maier, A., Bilban, M., Ghaffari-Tabrizi, N., Wadsack, C., Lang, I., et al. Insulin control of placental gene expression shifts from mother to foetus over the course of pregnancy. Diabetologia 49 (2006), 123–131.
    • (2006) Diabetologia , vol.49 , pp. 123-131
    • Hiden, U.1    Maier, A.2    Bilban, M.3    Ghaffari-Tabrizi, N.4    Wadsack, C.5    Lang, I.6
  • 35
    • 84878540327 scopus 로고    scopus 로고
    • Placental contribution to the origins of sexual dimorphism in health and diseases: Sex chromosomes and epigenetics
    • Gabory, A., Roseboom, T.J., Moore, T., Moore, L.G., Junien, C., Placental contribution to the origins of sexual dimorphism in health and diseases: Sex chromosomes and epigenetics. Biol Sex Differ, 4, 2013, 5.
    • (2013) Biol Sex Differ , vol.4 , pp. 5
    • Gabory, A.1    Roseboom, T.J.2    Moore, T.3    Moore, L.G.4    Junien, C.5
  • 36
    • 0035406530 scopus 로고    scopus 로고
    • Placental development: Lessons from mouse mutants
    • Rossant, J., Cross, J.C., Placental development: Lessons from mouse mutants. Nat Rev Genet 2 (2001), 538–548.
    • (2001) Nat Rev Genet , vol.2 , pp. 538-548
    • Rossant, J.1    Cross, J.C.2
  • 37
    • 84857373125 scopus 로고    scopus 로고
    • Rat placentation: An experimental model for investigating the hemochorial maternal–fetal interface
    • Soares, M.J., Chakraborty, D., Karim Rumi, M.A., Konno, T., Renaud, S.J., Rat placentation: An experimental model for investigating the hemochorial maternal–fetal interface. Placenta 33 (2012), 233–243.
    • (2012) Placenta , vol.33 , pp. 233-243
    • Soares, M.J.1    Chakraborty, D.2    Karim Rumi, M.A.3    Konno, T.4    Renaud, S.J.5
  • 38
    • 34247240533 scopus 로고    scopus 로고
    • Expression of Cre recombinase in early diploid trophoblast cells of the mouse placenta
    • Wenzel, P.L., Leone, G., Expression of Cre recombinase in early diploid trophoblast cells of the mouse placenta. Genesis 45 (2007), 129–134.
    • (2007) Genesis , vol.45 , pp. 129-134
    • Wenzel, P.L.1    Leone, G.2
  • 39
    • 84903287131 scopus 로고    scopus 로고
    • Prenatal stress-induced increases in placental inflammation and offspring hyperactivity are male-specific and ameliorated by maternal antiinflammatory treatment
    • Bronson, S.L., Bale, T.L., Prenatal stress-induced increases in placental inflammation and offspring hyperactivity are male-specific and ameliorated by maternal antiinflammatory treatment. Endocrinology 155 (2014), 2635–2646.
    • (2014) Endocrinology , vol.155 , pp. 2635-2646
    • Bronson, S.L.1    Bale, T.L.2
  • 41
    • 84878580738 scopus 로고    scopus 로고
    • The Subread aligner: Fast, accurate and scalable read mapping by seed-and-vote
    • Liao, Y., Smyth, G.K., Shi, W., The Subread aligner: Fast, accurate and scalable read mapping by seed-and-vote. Nucleic Acids Res, 41, 2013, e108.
    • (2013) Nucleic Acids Res , vol.41 , pp. e108
    • Liao, Y.1    Smyth, G.K.2    Shi, W.3
  • 42
    • 0038054341 scopus 로고    scopus 로고
    • PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
    • Mootha, V.K., Lindgren, C.M., Eriksson, K.-F., Subramanian, A., Sihag, S., Lehar, J., et al. PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34 (2003), 267–273.
    • (2003) Nat Genet , vol.34 , pp. 267-273
    • Mootha, V.K.1    Lindgren, C.M.2    Eriksson, K.-F.3    Subramanian, A.4    Sihag, S.5    Lehar, J.6
  • 43
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian, A., Tamayo, P., Mootha, V.K., Mukherjee, S., Ebert, B.L., Gillette, M.A., et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 102 (2005), 15545–15550.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3    Mukherjee, S.4    Ebert, B.L.5    Gillette, M.A.6
  • 44
    • 77958471357 scopus 로고    scopus 로고
    • Differential expression analysis for sequence count data
    • Anders, S., Huber, W., Differential expression analysis for sequence count data. Genome Biol, 11, 2010, R106.
    • (2010) Genome Biol , vol.11 , pp. R106
    • Anders, S.1    Huber, W.2
  • 45
    • 41349115432 scopus 로고    scopus 로고
    • The DAVID gene functional classification tool: A novel biological module-centric algorithm to functionally analyze large gene lists
    • Huang, D.W., Sherman, B.T., Tan, Q., Collins, J.R., Alvord, W.G., Roayaei, J., et al. The DAVID gene functional classification tool: A novel biological module-centric algorithm to functionally analyze large gene lists. Genome Biol, 8, 2007, R183.
    • (2007) Genome Biol , vol.8 , pp. R183
    • Huang, D.W.1    Sherman, B.T.2    Tan, Q.3    Collins, J.R.4    Alvord, W.G.5    Roayaei, J.6
  • 46
    • 0031238774 scopus 로고    scopus 로고
    • Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development
    • Louvi, A., Accili, D., Efstratiadis, A., Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development. Dev Biol 189 (1997), 33–48.
    • (1997) Dev Biol , vol.189 , pp. 33-48
    • Louvi, A.1    Accili, D.2    Efstratiadis, A.3
  • 47
    • 84896732337 scopus 로고    scopus 로고
    • Assessing behavioural and cognitive domains of autism spectrum disorders in rodents: Current status and future perspectives
    • Kas, M.J., Glennon, J.C., Buitelaar, J., Ey, E., Biemans, B., Crawley, J., et al. Assessing behavioural and cognitive domains of autism spectrum disorders in rodents: Current status and future perspectives. Psychopharmacology (Berl) 231 (2014), 1125–1146.
    • (2014) Psychopharmacology (Berl) , vol.231 , pp. 1125-1146
    • Kas, M.J.1    Glennon, J.C.2    Buitelaar, J.3    Ey, E.4    Biemans, B.5    Crawley, J.6
  • 48
    • 33745190239 scopus 로고    scopus 로고
    • Schizophrenia-relevant behavioral testing in rodent models: A uniquely human disorder?
    • Powell, C.M., Miyakawa, T., Schizophrenia-relevant behavioral testing in rodent models: A uniquely human disorder?. Biol Psychiatry 59 (2006), 1198–1207.
    • (2006) Biol Psychiatry , vol.59 , pp. 1198-1207
    • Powell, C.M.1    Miyakawa, T.2
  • 49
    • 79956208485 scopus 로고    scopus 로고
    • Translating cognition from animals to humans
    • Keeler, J.F., Robbins, T.W., Translating cognition from animals to humans. Biochem Pharmacol 81 (2011), 1356–1366.
    • (2011) Biochem Pharmacol , vol.81 , pp. 1356-1366
    • Keeler, J.F.1    Robbins, T.W.2
  • 50
    • 0027200692 scopus 로고
    • The role of the medial prefrontal cortex (cingulate gyrus) in the regulation of hypothalamic–pituitary–adrenal responses to stress
    • Diorio, D., Viau, V., Meaney, M.J., The role of the medial prefrontal cortex (cingulate gyrus) in the regulation of hypothalamic–pituitary–adrenal responses to stress. J Neurosci 13 (1993), 3839–3847.
    • (1993) J Neurosci , vol.13 , pp. 3839-3847
    • Diorio, D.1    Viau, V.2    Meaney, M.J.3
  • 51
    • 84929741102 scopus 로고    scopus 로고
    • The medial prefrontal cortex: Coordinator of autonomic, neuroendocrine and behavioural responses to stress
    • McKlveen, J.M., Myers, B., Herman, J.P., The medial prefrontal cortex: Coordinator of autonomic, neuroendocrine and behavioural responses to stress. J Neuroendocrinol 27 (2015), 446–456.
    • (2015) J Neuroendocrinol , vol.27 , pp. 446-456
    • McKlveen, J.M.1    Myers, B.2    Herman, J.P.3
  • 52
    • 33845615546 scopus 로고    scopus 로고
    • Regional differentiation of the medial prefrontal cortex in regulating adaptive responses to acute emotional stress
    • Radley, J.J., Arias, C.M., Sawchenko, P.E., Regional differentiation of the medial prefrontal cortex in regulating adaptive responses to acute emotional stress. J Neurosci 26 (2006), 12967–12976.
    • (2006) J Neurosci , vol.26 , pp. 12967-12976
    • Radley, J.J.1    Arias, C.M.2    Sawchenko, P.E.3
  • 53
    • 84994682761 scopus 로고    scopus 로고
    • Schizophrenia: A tale of two critical periods for prefrontal cortical development
    • Selemon, L.D., Zecevic, N., Schizophrenia: A tale of two critical periods for prefrontal cortical development. Transl Psychiatry, 5, 2015, e623.
    • (2015) Transl Psychiatry , vol.5 , pp. e623
    • Selemon, L.D.1    Zecevic, N.2
  • 54
    • 0034927844 scopus 로고    scopus 로고
    • Neural circuit regulation of prepulse inhibition of startle in the rat: Current knowledge and future challenges
    • Swerdlow, N.R., Geyer, M.A., Braff, D.L., Neural circuit regulation of prepulse inhibition of startle in the rat: Current knowledge and future challenges. Psychopharmacology (Berl) 156 (2001), 194–215.
    • (2001) Psychopharmacology (Berl) , vol.156 , pp. 194-215
    • Swerdlow, N.R.1    Geyer, M.A.2    Braff, D.L.3
  • 55
    • 0034891977 scopus 로고    scopus 로고
    • Human studies of prepulse inhibition of startle: Normal subjects, patient groups, and pharmacological studies
    • Braff, D.L., Geyer, M.A., Swerdlow, N.R., Human studies of prepulse inhibition of startle: Normal subjects, patient groups, and pharmacological studies. Psychopharmacology (Berl) 156 (2001), 234–258.
    • (2001) Psychopharmacology (Berl) , vol.156 , pp. 234-258
    • Braff, D.L.1    Geyer, M.A.2    Swerdlow, N.R.3
  • 56
    • 84876004502 scopus 로고    scopus 로고
    • Placental serotonin: Implications for the developmental effects of SSRIs and maternal depression
    • Velasquez, J.C., Goeden, N., Bonnin, A., Placental serotonin: Implications for the developmental effects of SSRIs and maternal depression. Front Cell Neurosci, 7, 2013, 47.
    • (2013) Front Cell Neurosci , vol.7 , pp. 47
    • Velasquez, J.C.1    Goeden, N.2    Bonnin, A.3
  • 57
    • 60549089578 scopus 로고    scopus 로고
    • Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6
    • Riccio, O., Potter, G., Walzer, C., Vallet, P., Szabó, G., Vutskits, L., et al. Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6. Mol Psychiatry 14 (2009), 280–290.
    • (2009) Mol Psychiatry , vol.14 , pp. 280-290
    • Riccio, O.1    Potter, G.2    Walzer, C.3    Vallet, P.4    Szabó, G.5    Vutskits, L.6
  • 58
    • 82855166035 scopus 로고    scopus 로고
    • Fetal, maternal, and placental sources of serotonin and new implications for developmental programming of the brain
    • Bonnin, A., Levitt, P., Fetal, maternal, and placental sources of serotonin and new implications for developmental programming of the brain. Neuroscience 197 (2011), 1–7.
    • (2011) Neuroscience , vol.197 , pp. 1-7
    • Bonnin, A.1    Levitt, P.2
  • 59
    • 34247514888 scopus 로고    scopus 로고
    • Serotonin modulates the response of embryonic thalamocortical axons to netrin-1
    • Bonnin, A., Torii, M., Wang, L., Rakic, P., Levitt, P., Serotonin modulates the response of embryonic thalamocortical axons to netrin-1. Nat Neurosci 10 (2007), 588–597.
    • (2007) Nat Neurosci , vol.10 , pp. 588-597
    • Bonnin, A.1    Torii, M.2    Wang, L.3    Rakic, P.4    Levitt, P.5
  • 60
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da, W., Sherman, B.T., Lempicki, R.A., Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4 (2009), 44–57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 61
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
    • Huang da, W., Sherman, B.T., Lempicki, R.A., Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37 (2009), 1–13.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1-13
    • Huang da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 62
    • 0037093781 scopus 로고    scopus 로고
    • Stress activation of glutamate neurotransmission in the prefrontal cortex: Implications for dopamine-associated psychiatric disorders
    • Moghaddam, B., Stress activation of glutamate neurotransmission in the prefrontal cortex: Implications for dopamine-associated psychiatric disorders. Biol Psychiatry 51 (2002), 775–787.
    • (2002) Biol Psychiatry , vol.51 , pp. 775-787
    • Moghaddam, B.1
  • 64
    • 43449101561 scopus 로고    scopus 로고
    • Stress and the hypothalamic pituitary adrenal axis in the developmental course of schizophrenia
    • Walker, E., Mittal, V., Tessner, K., Stress and the hypothalamic pituitary adrenal axis in the developmental course of schizophrenia. Annu Rev Clin Psychol 4 (2008), 189–216.
    • (2008) Annu Rev Clin Psychol , vol.4 , pp. 189-216
    • Walker, E.1    Mittal, V.2    Tessner, K.3
  • 65
    • 63449110599 scopus 로고    scopus 로고
    • Comparing cortisol, stress, and sensory sensitivity in children with autism
    • Corbett, B.A., Schupp, C.W., Levine, S., Mendoza, S., Comparing cortisol, stress, and sensory sensitivity in children with autism. Autism Res 2 (2009), 39–49.
    • (2009) Autism Res , vol.2 , pp. 39-49
    • Corbett, B.A.1    Schupp, C.W.2    Levine, S.3    Mendoza, S.4
  • 66
    • 35448976848 scopus 로고    scopus 로고
    • Primary and secondary neural networks of auditory prepulse inhibition: A functional magnetic resonance imaging study of sensorimotor gating of the human acoustic startle response
    • Campbell, L.E., Hughes, M., Budd, T.W., Cooper, G., Fulham, W.R., Karayanidis, F., et al. Primary and secondary neural networks of auditory prepulse inhibition: A functional magnetic resonance imaging study of sensorimotor gating of the human acoustic startle response. Eur J Neurosci 26 (2007), 2327–2333.
    • (2007) Eur J Neurosci , vol.26 , pp. 2327-2333
    • Campbell, L.E.1    Hughes, M.2    Budd, T.W.3    Cooper, G.4    Fulham, W.R.5    Karayanidis, F.6
  • 67
    • 78049488635 scopus 로고    scopus 로고
    • Changes in prefrontal axons may disrupt the network in autism
    • Zikopoulos, B., Barbas, H., Changes in prefrontal axons may disrupt the network in autism. J Neurosci 30 (2010), 14595–14609.
    • (2010) J Neurosci , vol.30 , pp. 14595-14609
    • Zikopoulos, B.1    Barbas, H.2
  • 68
    • 48249096330 scopus 로고    scopus 로고
    • Adrenomedullin protects neurons against oxygen glucose deprivation stress in an autocrine and paracrine manner
    • Tixier, E., Leconte, C., Touzani, O., Roussel, S., Petit, E., Bernaudin, M., Adrenomedullin protects neurons against oxygen glucose deprivation stress in an autocrine and paracrine manner. J Neurochem 106 (2008), 1388–1403.
    • (2008) J Neurochem , vol.106 , pp. 1388-1403
    • Tixier, E.1    Leconte, C.2    Touzani, O.3    Roussel, S.4    Petit, E.5    Bernaudin, M.6
  • 69
    • 9144251741 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone and its structurally related urocortin are synthesized and secreted by human mast cells
    • Kempuraj, D., Papadopoulou, N.G., Lytinas, M., Huang, M., Kandere-Grzybowska, K., Madhappan, B., et al. Corticotropin-releasing hormone and its structurally related urocortin are synthesized and secreted by human mast cells. Endocrinology 145 (2004), 43–48.
    • (2004) Endocrinology , vol.145 , pp. 43-48
    • Kempuraj, D.1    Papadopoulou, N.G.2    Lytinas, M.3    Huang, M.4    Kandere-Grzybowska, K.5    Madhappan, B.6
  • 71
    • 34247490186 scopus 로고    scopus 로고
    • Mitochondria, oxidative stress and cell death
    • Ott, M., Gogvadze, V., Orrenius, S., Zhivotovsky, B., Mitochondria, oxidative stress and cell death. Apoptosis 12 (2007), 913–922.
    • (2007) Apoptosis , vol.12 , pp. 913-922
    • Ott, M.1    Gogvadze, V.2    Orrenius, S.3    Zhivotovsky, B.4
  • 75
    • 0036430378 scopus 로고    scopus 로고
    • State-dependent alterations in mitochondrial complex I activity in platelets: A potential peripheral marker for schizophrenia
    • Dror, N., Klein, E., Karry, R., Sheinkman, A., Kirsh, Z., Mazor, M., et al. State-dependent alterations in mitochondrial complex I activity in platelets: A potential peripheral marker for schizophrenia. Mol Psychiatry 7 (2002), 995–1001.
    • (2002) Mol Psychiatry , vol.7 , pp. 995-1001
    • Dror, N.1    Klein, E.2    Karry, R.3    Sheinkman, A.4    Kirsh, Z.5    Mazor, M.6
  • 76
    • 84964535271 scopus 로고    scopus 로고
    • Evidence of mitochondrial dysfunction within the complex genetic etiology of schizophrenia
    • Hjelm, B.E., Rollins, B., Mamdani, F., Lauterborn, J.C., Kirov, G., Lynch, G., et al. Evidence of mitochondrial dysfunction within the complex genetic etiology of schizophrenia. Mol Neuropsychiatry 1 (2015), 201–219.
    • (2015) Mol Neuropsychiatry , vol.1 , pp. 201-219
    • Hjelm, B.E.1    Rollins, B.2    Mamdani, F.3    Lauterborn, J.C.4    Kirov, G.5    Lynch, G.6
  • 77
    • 84923912066 scopus 로고    scopus 로고
    • Umbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunction
    • Kim, J., Piao, Y., Pak, Y.K., Chung, D., Han, Y.M., Hong, J.S., et al. Umbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunction. Stem Cells Dev 24 (2015), 575–586.
    • (2015) Stem Cells Dev , vol.24 , pp. 575-586
    • Kim, J.1    Piao, Y.2    Pak, Y.K.3    Chung, D.4    Han, Y.M.5    Hong, J.S.6
  • 78
    • 40849142338 scopus 로고    scopus 로고
    • SLC25A12 expression is associated with neurite outgrowth and is upregulated in the prefrontal cortex of autistic subjects
    • Lepagnol-Bestel, A.-M., Maussion, G., Boda, B., Cardona, A., Iwayama, Y., Delezoide, A.-L., et al. SLC25A12 expression is associated with neurite outgrowth and is upregulated in the prefrontal cortex of autistic subjects. Mol Psychiatry 13 (2008), 385–397.
    • (2008) Mol Psychiatry , vol.13 , pp. 385-397
    • Lepagnol-Bestel, A.-M.1    Maussion, G.2    Boda, B.3    Cardona, A.4    Iwayama, Y.5    Delezoide, A.-L.6
  • 79
    • 84961290064 scopus 로고    scopus 로고
    • Placental contribution to nutritional programming of health and diseases: Epigenetics and sexual dimorphism
    • Tarrade, A., Panchenko, P., Junien, C., Gabory, A., Placental contribution to nutritional programming of health and diseases: Epigenetics and sexual dimorphism. J Exp Biol 218 (2015), 50–58.
    • (2015) J Exp Biol , vol.218 , pp. 50-58
    • Tarrade, A.1    Panchenko, P.2    Junien, C.3    Gabory, A.4
  • 80
    • 84877054863 scopus 로고    scopus 로고
    • Modulation of cholesterol transport by insulin-treated gestational diabetes mellitus in human full-term placenta
    • Dubé, E., Ethier-Chiasson, M., Lafond, J., Modulation of cholesterol transport by insulin-treated gestational diabetes mellitus in human full-term placenta. Biol Reprod, 88, 2013, 16.
    • (2013) Biol Reprod , vol.88 , pp. 16
    • Dubé, E.1    Ethier-Chiasson, M.2    Lafond, J.3
  • 81
    • 85007403703 scopus 로고    scopus 로고
    • Maternal and fetal lipid metabolism under normal and gestational diabetic conditions
    • Herrera, E., Desoye, G., Maternal and fetal lipid metabolism under normal and gestational diabetic conditions. Horm Mol Biol Clin Investig 26 (2016), 109–127.
    • (2016) Horm Mol Biol Clin Investig , vol.26 , pp. 109-127
    • Herrera, E.1    Desoye, G.2
  • 82
    • 56049114202 scopus 로고    scopus 로고
    • Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith–Lemli–Opitz syndrome
    • Lindegaard, M.L., Wassif, C.A., Vaisman, B., Amar, M., Wasmuth, E.V., Shamburek, R., et al. Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith–Lemli–Opitz syndrome. Hum Mol Genet 17 (2008), 3806–3813.
    • (2008) Hum Mol Genet , vol.17 , pp. 3806-3813
    • Lindegaard, M.L.1    Wassif, C.A.2    Vaisman, B.3    Amar, M.4    Wasmuth, E.V.5    Shamburek, R.6
  • 83
    • 33845579126 scopus 로고    scopus 로고
    • Placental triglyceride accumulation in maternal type 1 diabetes is associated with increased lipase gene expression
    • Lindegaard, M.L.S., Damm, P., Mathiesen, E.R., Nielsen, L.B., Placental triglyceride accumulation in maternal type 1 diabetes is associated with increased lipase gene expression. J Lipid Res 47 (2006), 2581–2588.
    • (2006) J Lipid Res , vol.47 , pp. 2581-2588
    • Lindegaard, M.L.S.1    Damm, P.2    Mathiesen, E.R.3    Nielsen, L.B.4
  • 85
    • 69249156542 scopus 로고    scopus 로고
    • Expression of placental serotonin transporter and 5-HT 2A receptor in normal and gestational diabetes mellitus pregnancies
    • Viau, M., Lafond, J., Vaillancourt, C., Expression of placental serotonin transporter and 5-HT 2A receptor in normal and gestational diabetes mellitus pregnancies. Reprod Biomed Online 19 (2009), 207–215.
    • (2009) Reprod Biomed Online , vol.19 , pp. 207-215
    • Viau, M.1    Lafond, J.2    Vaillancourt, C.3
  • 86
    • 79955447412 scopus 로고    scopus 로고
    • A transient placental source of serotonin for the fetal forebrain
    • Bonnin, A., Goeden, N., Chen, K., Wilson, M.L., King, J., Shih, J.C., et al. A transient placental source of serotonin for the fetal forebrain. Nature 472 (2011), 347–350.
    • (2011) Nature , vol.472 , pp. 347-350
    • Bonnin, A.1    Goeden, N.2    Chen, K.3    Wilson, M.L.4    King, J.5    Shih, J.C.6
  • 87
    • 84866912634 scopus 로고    scopus 로고
    • UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development
    • Shpargel, K.B., Sengoku, T., Yokoyama, S., Magnuson, T., UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development. PLoS Genet, 8, 2012, e1002964.
    • (2012) PLoS Genet , vol.8 , pp. e1002964
    • Shpargel, K.B.1    Sengoku, T.2    Yokoyama, S.3    Magnuson, T.4
  • 88
    • 84868371230 scopus 로고    scopus 로고
    • Maternal diets trigger sex-specific divergent trajectories of gene expression and epigenetic systems in mouse placenta
    • Gabory, A., Ferry, L., Fajardy, I., Jouneau, L., Gothié, J.-D., Vigé, A., et al. Maternal diets trigger sex-specific divergent trajectories of gene expression and epigenetic systems in mouse placenta. PLoS One, 7, 2012, e47986.
    • (2012) PLoS One , vol.7 , pp. e47986
    • Gabory, A.1    Ferry, L.2    Fajardy, I.3    Jouneau, L.4    Gothié, J.-D.5    Vigé, A.6
  • 89
    • 0141953237 scopus 로고    scopus 로고
    • Cytoskeletal dynamics and transport in growth cone motility and axon guidance
    • Dent, E.W., Gertler, F.B., Cytoskeletal dynamics and transport in growth cone motility and axon guidance. Neuron 40 (2003), 209–227.
    • (2003) Neuron , vol.40 , pp. 209-227
    • Dent, E.W.1    Gertler, F.B.2
  • 90
    • 33846040831 scopus 로고    scopus 로고
    • Trekking across the brain: The journey of neuronal migration
    • Ayala, R., Shu, T., Tsai, L.-H., Trekking across the brain: The journey of neuronal migration. Cell 128 (2007), 29–43.
    • (2007) Cell , vol.128 , pp. 29-43
    • Ayala, R.1    Shu, T.2    Tsai, L.-H.3
  • 91
    • 0036719449 scopus 로고    scopus 로고
    • Breaking the neuronal sphere: Regulation of the actin cytoskeleton in neuritogenesis
    • da Silva, J.S., Dotti, C.G., Breaking the neuronal sphere: Regulation of the actin cytoskeleton in neuritogenesis. Nat Rev Neurosci 3 (2002), 694–704.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 694-704
    • da Silva, J.S.1    Dotti, C.G.2
  • 92
    • 84903701413 scopus 로고    scopus 로고
    • Retardation of fetal dendritic development induced by gestational hyperglycemia is associated with brain insulin/IGF-I signals
    • Jing, Y.-H., Song, Y.-F., Yao, Y.-M., Yin, J., Wang, D.-G., Gao, L.-P., Retardation of fetal dendritic development induced by gestational hyperglycemia is associated with brain insulin/IGF-I signals. Int J Dev Neurosci 37 (2014), 15–20.
    • (2014) Int J Dev Neurosci , vol.37 , pp. 15-20
    • Jing, Y.-H.1    Song, Y.-F.2    Yao, Y.-M.3    Yin, J.4    Wang, D.-G.5    Gao, L.-P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.