-
1
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
International Human Genome Sequencing Consortium
-
Lander ES, et al.; International Human Genome Sequencing Consortium (2001) Initial sequencing and analysis of the human genome. Nature 409(6822):860-921.
-
(2001)
Nature
, vol.409
, Issue.6822
, pp. 860-921
-
-
Lander, E.S.1
-
2
-
-
84860879005
-
Human transposon tectonics
-
Burns KH, Boeke JD (2012) Human transposon tectonics. Cell 149(4):740-752.
-
(2012)
Cell
, vol.149
, Issue.4
, pp. 740-752
-
-
Burns, K.H.1
Boeke, J.D.2
-
3
-
-
0034086210
-
L1 (LINE-1) retrotransposon evolution and amplification in recent human history
-
Boissinot S, Chevret P, Furano AV (2000) L1 (LINE-1) retrotransposon evolution and amplification in recent human history. Mol Biol Evol 17(6):915-928.
-
(2000)
Mol Biol Evol
, vol.17
, Issue.6
, pp. 915-928
-
-
Boissinot, S.1
Chevret, P.2
Furano, A.V.3
-
4
-
-
0023948714
-
Unit-length line-1 transcripts in human teratocarcinoma cells
-
Skowronski J, Fanning TG, Singer MF (1988) Unit-length line-1 transcripts in human teratocarcinoma cells. Mol Cell Biol 8(4):1385-1397.
-
(1988)
Mol Cell Biol
, vol.8
, Issue.4
, pp. 1385-1397
-
-
Skowronski, J.1
Fanning, T.G.2
Singer, M.F.3
-
5
-
-
0033786249
-
Reading between the LINEs: Human genomic variation induced by LINE-1 retrotransposition
-
Sheen FM, et al. (2000) Reading between the LINEs: Human genomic variation induced by LINE-1 retrotransposition. Genome Res 10(10):1496-1508.
-
(2000)
Genome Res
, vol.10
, Issue.10
, pp. 1496-1508
-
-
Sheen, F.M.1
-
6
-
-
0041353551
-
LINE-mediated retrotransposition of marked Alu sequences
-
Dewannieux M, Esnault C, Heidmann T (2003) LINE-mediated retrotransposition of marked Alu sequences. Nat Genet 35(1):41-48.
-
(2003)
Nat Genet
, vol.35
, Issue.1
, pp. 41-48
-
-
Dewannieux, M.1
Esnault, C.2
Heidmann, T.3
-
7
-
-
80051702066
-
Retrotransposition of marked SVA elements by human L1s in cultured cells
-
Hancks DC, Goodier JL, Mandal PK, Cheung LE, Kazazian HH, Jr (2011) Retrotransposition of marked SVA elements by human L1s in cultured cells. Hum Mol Genet 20(17):3386-3400.
-
(2011)
Hum Mol Genet
, vol.20
, Issue.17
, pp. 3386-3400
-
-
Hancks, D.C.1
Goodier, J.L.2
Mandal, P.K.3
Cheung, L.E.4
Kazazian, H.H.5
-
8
-
-
0034079713
-
Human LINE retrotransposons generate processed pseudogenes
-
Esnault C, Maestre J, Heidmann T (2000) Human LINE retrotransposons generate processed pseudogenes. Nat Genet 24(4):363-367.
-
(2000)
Nat Genet
, vol.24
, Issue.4
, pp. 363-367
-
-
Esnault, C.1
Maestre, J.2
Heidmann, T.3
-
9
-
-
0027450385
-
Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotransposition
-
Luan DD, Korman MH, Jakubczak JL, Eickbush TH (1993) Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotransposition. Cell 72(4):595-605.
-
(1993)
Cell
, vol.72
, Issue.4
, pp. 595-605
-
-
Luan, D.D.1
Korman, M.H.2
Jakubczak, J.L.3
Eickbush, T.H.4
-
10
-
-
0036847319
-
Human L1 element target-primed reverse transcription in vitro
-
Cost GJ, Feng Q, Jacquier A, Boeke JD (2002) Human L1 element target-primed reverse transcription in vitro. EMBO J 21(21):5899-5910.
-
(2002)
EMBO J
, vol.21
, Issue.21
, pp. 5899-5910
-
-
Cost, G.J.1
Feng, Q.2
Jacquier, A.3
Boeke, J.D.4
-
11
-
-
0035208118
-
Twin priming: A proposed mechanism for the creation of inversions in L1 retrotransposition
-
Ostertag EM, Kazazian HH, Jr (2001) Twin priming: A proposed mechanism for the creation of inversions in L1 retrotransposition. Genome Res 11(12):2059-2065.
-
(2001)
Genome Res
, vol.11
, Issue.12
, pp. 2059-2065
-
-
Ostertag, E.M.1
Kazazian, H.H.2
-
12
-
-
0034161961
-
Transduction of 3'-flanking sequences is common in L1 retrotransposition
-
Goodier JL, Ostertag EM, Kazazian HH, Jr (2000) Transduction of 3'-flanking sequences is common in L1 retrotransposition. Hum Mol Genet 9(4):653-657.
-
(2000)
Hum Mol Genet
, vol.9
, Issue.4
, pp. 653-657
-
-
Goodier, J.L.1
Ostertag, E.M.2
Kazazian, H.H.3
-
13
-
-
0342313559
-
Frequent human genomic DNA transduction driven by LINE-1 retrotransposition
-
Pickeral OK, Makalowski W, Boguski MS, Boeke JD (2000) Frequent human genomic DNA transduction driven by LINE-1 retrotransposition. Genome Res 10(4):411-415.
-
(2000)
Genome Res
, vol.10
, Issue.4
, pp. 411-415
-
-
Pickeral, O.K.1
Makalowski, W.2
Boguski, M.S.3
Boeke, J.D.4
-
14
-
-
0037047396
-
Human l1 retrotransposition is associated with genetic instability in vivo
-
Symer DE, et al. (2002) Human l1 retrotransposition is associated with genetic instability in vivo. Cell 110(3):327-338.
-
(2002)
Cell
, vol.110
, Issue.3
, pp. 327-338
-
-
Symer, D.E.1
-
15
-
-
77953889472
-
Natural mutagenesis of human genomes by endogenous retrotransposons
-
Iskow RC, et al. (2010) Natural mutagenesis of human genomes by endogenous retrotransposons. Cell 141(7):1253-1261.
-
(2010)
Cell
, vol.141
, Issue.7
, pp. 1253-1261
-
-
Iskow, R.C.1
-
16
-
-
77955160719
-
High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes
-
Ewing AD, Kazazian HH, Jr (2010) High-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomes. Genome Res 20(9):1262-1270.
-
(2010)
Genome Res
, vol.20
, Issue.9
, pp. 1262-1270
-
-
Ewing, A.D.1
Kazazian, H.H.2
-
17
-
-
77953892366
-
Mobile interspersed repeats are major structural variants in the human genome
-
Huang CR, et al. (2010) Mobile interspersed repeats are major structural variants in the human genome. Cell 141(7):1171-1182.
-
(2010)
Cell
, vol.141
, Issue.7
, pp. 1171-1182
-
-
Huang, C.R.1
-
18
-
-
84961266736
-
Resolving rates of mutation in the brain using single-neuron genomics
-
Evrony GD, Lee E, Park PJ, Walsh CA (2016) Resolving rates of mutation in the brain using single-neuron genomics. eLife 5:e12966.
-
(2016)
ELife
, vol.5
-
-
Evrony, G.D.1
Lee, E.2
Park, P.J.3
Walsh, C.A.4
-
19
-
-
84875698271
-
Endogenous retrotransposition activates oncogenic pathways in hepatocellular carcinoma
-
Shukla R, et al. (2013) Endogenous retrotransposition activates oncogenic pathways in hepatocellular carcinoma. Cell 153(1):101-111.
-
(2013)
Cell
, vol.153
, Issue.1
, pp. 101-111
-
-
Shukla, R.1
-
20
-
-
79957933956
-
Whole-genome resequencing allows detection of many rare LINE-1 insertion alleles in humans
-
Ewing AD, Kazazian HH, Jr (2011) Whole-genome resequencing allows detection of many rare LINE-1 insertion alleles in humans. Genome Res 21(6):985-990.
-
(2011)
Genome Res
, vol.21
, Issue.6
, pp. 985-990
-
-
Ewing, A.D.1
Kazazian, H.H.2
-
21
-
-
80052318161
-
A comprehensive map of mobile element insertion polymorphisms in humans
-
1000 Genomes Project
-
Stewart C, et al.; 1000 Genomes Project (2011) A comprehensive map of mobile element insertion polymorphisms in humans. PLoS Genet 7(8):e1002236.
-
(2011)
PLoS Genet
, vol.7
, Issue.8
-
-
Stewart, C.1
-
22
-
-
84865285978
-
Landscape of somatic retrotransposition in human cancers
-
Cancer Genome Atlas Research Network
-
Lee E, et al.; Cancer Genome Atlas Research Network (2012) Landscape of somatic retrotransposition in human cancers. Science 337(6097):967-971.
-
(2012)
Science
, vol.337
, Issue.6097
, pp. 967-971
-
-
Lee, E.1
-
23
-
-
84905900534
-
Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L 1 retrotransposition in cancer genomes
-
Tubio JM, et al.; ICGC Breast Cancer Group; ICGC Bone Cancer Group; ICGC Prostate Cancer Group (2014) Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes. Science 345(6196): 1251343.
-
(2014)
Science
, vol.345
, Issue.6196
, pp. 1251343
-
-
Tubio, J.M.1
-
24
-
-
84870482898
-
Extensive somatic L1 retrotransposition in colorectal tumors
-
Solyom S, et al. (2012) Extensive somatic L1 retrotransposition in colorectal tumors. Genome Res 22(12):2328-2338.
-
(2012)
Genome Res
, vol.22
, Issue.12
, pp. 2328-2338
-
-
Solyom, S.1
-
25
-
-
84941923663
-
Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution
-
Ewing AD, et al. (2015) Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution. Genome Res 25(10):1536-1545.
-
(2015)
Genome Res
, vol.25
, Issue.10
, pp. 1536-1545
-
-
Ewing, A.D.1
-
26
-
-
84940979605
-
LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma
-
Doucet-O'Hare TT, et al. (2015) LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma. Proc Natl Acad Sci USA 112(35):E4894-E4900.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, Issue.35
, pp. E4894-E4900
-
-
Doucet-O'Hare, T.T.1
-
27
-
-
84941024427
-
Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma
-
Rodic N, et al. (2015) Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma. Nat Med 21(9):1060-1064.
-
(2015)
Nat Med
, vol.21
, Issue.9
, pp. 1060-1064
-
-
Rodic, N.1
-
28
-
-
33845204670
-
Transposon insertion site profiling chip (TIP-chip)
-
Wheelan SJ, Scheifele LZ, Martínez-Murillo F, Irizarry RA, Boeke JD (2006) Transposon insertion site profiling chip (TIP-chip). Proc Natl Acad Sci USA 103(47):17632-17637.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.47
, pp. 17632-17637
-
-
Wheelan, S.J.1
Scheifele, L.Z.2
Martínez-Murillo, F.3
Irizarry, R.A.4
Boeke, J.D.5
-
29
-
-
0026207423
-
Vectorette PCR: A novel approach to genomic walking
-
Arnold C, Hodgson IJ (1991) Vectorette PCR: A novel approach to genomic walking. PCR Methods Appl 1(1):39-42.
-
(1991)
PCR Methods Appl
, vol.1
, Issue.1
, pp. 39-42
-
-
Arnold, C.1
Hodgson, I.J.2
-
30
-
-
0031857588
-
Molecular screening for P-element insertions in a large genomic region of Drosophila melanogaster using polymerase chain reaction mediated by the vectorette
-
Eggert H, Bergemann K, Saumweber H (1998) Molecular screening for P-element insertions in a large genomic region of Drosophila melanogaster using polymerase chain reaction mediated by the vectorette. Genetics 149(3):1427-1434.
-
(1998)
Genetics
, vol.149
, Issue.3
, pp. 1427-1434
-
-
Eggert, H.1
Bergemann, K.2
Saumweber, H.3
-
31
-
-
84905049901
-
Trimmomatic: A flexible trimmer for Illumina sequence data
-
Bolger AM, Lohse M, Usadel B (2014) Trimmomatic: A flexible trimmer for Illumina sequence data. Bioinformatics 30(15):2114-2120.
-
(2014)
Bioinformatics
, vol.30
, Issue.15
, pp. 2114-2120
-
-
Bolger, A.M.1
Lohse, M.2
Usadel, B.3
-
32
-
-
62349130698
-
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
-
Langmead B, Trapnell C, Pop M, Salzberg SL (2009) Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 10(3):R25.
-
(2009)
Genome Biol
, vol.10
, Issue.3
, pp. R25
-
-
Langmead, B.1
Trapnell, C.2
Pop, M.3
Salzberg, S.L.4
-
34
-
-
77951770756
-
BEDTools: A flexible suite of utilities for comparing genomic features
-
Quinlan AR, Hall IM (2010) BEDTools: A flexible suite of utilities for comparing genomic features. Bioinformatics 26(6):841-842.
-
(2010)
Bioinformatics
, vol.26
, Issue.6
, pp. 841-842
-
-
Quinlan, A.R.1
Hall, I.M.2
-
35
-
-
0034284437
-
Repbase update: A database and an electronic journal of repetitive elements
-
Jurka J (2000) Repbase update: A database and an electronic journal of repetitive elements. Trends Genet 16(9):418-420.
-
(2000)
Trends Genet
, vol.16
, Issue.9
, pp. 418-420
-
-
Jurka, J.1
-
36
-
-
84878771050
-
Combining multiple ChIP-seq peak detection systems using combinatorial fusion
-
Schweikert C, Brown S, Tang Z, Smith PR, Hsu DF (2012) Combining multiple ChIP-seq peak detection systems using combinatorial fusion. BMC Genomics 13(Suppl 8):S12.
-
(2012)
BMC Genomics
, vol.13
, pp. S12
-
-
Schweikert, C.1
Brown, S.2
Tang, Z.3
Smith, P.R.4
Hsu, D.F.5
-
37
-
-
84899548825
-
Long interspersed element-1 protein expression is a hallmark of many human cancers
-
Rodic N, et al. (2014) Long interspersed element-1 protein expression is a hallmark of many human cancers. Am J Pathol 184(5):1280-1286.
-
(2014)
Am J Pathol
, vol.184
, Issue.5
, pp. 1280-1286
-
-
Rodic, N.1
-
38
-
-
84959216112
-
Combining Amplification Typing of L1 Active Subfamilies (ATLAS) with high-throughput sequencing
-
Rahbari R, Badge RM (2016) Combining Amplification Typing of L1 Active Subfamilies (ATLAS) with high-throughput sequencing. Methods Mol Biol 1400:95-106.
-
(2016)
Methods Mol Biol
, vol.1400
, pp. 95-106
-
-
Rahbari, R.1
Badge, R.M.2
-
39
-
-
84959200745
-
Retrotransposon Capture Sequencing (RC-Seq): A targeted, high-throughput approach to resolve somatic L1 retrotransposition in humans
-
Sanchez-Luque FJ, Richardson SR, Faulkner GJ (2016) Retrotransposon Capture Sequencing (RC-Seq): A targeted, high-throughput approach to resolve somatic L1 retrotransposition in humans. Methods Mol Biol 1400:47-77.
-
(2016)
Methods Mol Biol
, vol.1400
, pp. 47-77
-
-
Sanchez-Luque, F.J.1
Richardson, S.R.2
Faulkner, G.J.3
-
40
-
-
84927136066
-
Ubiquitous L1 mosaicism in hippocampal neurons
-
Upton KR, et al. (2015) Ubiquitous L1 mosaicism in hippocampal neurons. Cell 161(2): 228-239.
-
(2015)
Cell
, vol.161
, Issue.2
, pp. 228-239
-
-
Upton, K.R.1
-
41
-
-
84959218485
-
Long interspersed element sequencing (L1-Seq): A method to identify somatic LINE-1 insertions in the human genome
-
Doucet TT, Kazazian HH, Jr (2016) Long interspersed element sequencing (L1-Seq): A method to identify somatic LINE-1 insertions in the human genome. Methods Mol Biol 1400:79-93.
-
(2016)
Methods Mol Biol
, vol.1400
, pp. 79-93
-
-
Doucet, T.T.1
Kazazian, H.H.2
-
42
-
-
84925869415
-
Sequencing, identification and mapping of primed L1 elements (SIMPLE) reveals significant variation in full length L1 elements between individuals
-
Streva VA, et al. (2015) Sequencing, identification and mapping of primed L1 elements (SIMPLE) reveals significant variation in full length L1 elements between individuals. BMC Genomics 16:220.
-
(2015)
BMC Genomics
, vol.16
, pp. 220
-
-
Streva, V.A.1
-
43
-
-
84987617362
-
L1-associated genomic regions are deleted in somatic cells of the healthy human brain
-
Erwin JA, et al. (2016) L1-associated genomic regions are deleted in somatic cells of the healthy human brain. Nat Neurosci 19(12):1583-1591.
-
(2016)
Nat Neurosci
, vol.19
, Issue.12
, pp. 1583-1591
-
-
Erwin, J.A.1
-
44
-
-
84941135612
-
EuL1db: The European database of L1HS retrotransposon insertions in humans
-
Mir AA, Philippe C, Cristofari G (2015) euL1db: The European database of L1HS retrotransposon insertions in humans. Nucleic Acids Res 43(Database issue):D43-D47.
-
(2015)
Nucleic Acids Res
, vol.43
, Issue.DATABASE ISSUE
, pp. D43-D47
-
-
Mir, A.A.1
Philippe, C.2
Cristofari, G.3
-
45
-
-
77954038084
-
Mobile element scanning (ME-Scan) by targeted highthroughput sequencing
-
Witherspoon DJ, et al. (2010) Mobile element scanning (ME-Scan) by targeted highthroughput sequencing. BMC Genomics 11:410.
-
(2010)
BMC Genomics
, vol.11
, pp. 410
-
-
Witherspoon, D.J.1
-
46
-
-
84880066634
-
Mobile element scanning (ME-Scan) identifies thousands of novel Alu insertions in diverse human populations
-
Witherspoon DJ, et al. (2013) Mobile element scanning (ME-Scan) identifies thousands of novel Alu insertions in diverse human populations. Genome Res 23(7): 1170-1181.
-
(2013)
Genome Res
, vol.23
, Issue.7
, pp. 1170-1181
-
-
Witherspoon, D.J.1
-
47
-
-
84943182461
-
An integrated map of structural variation in 2,504 human genomes
-
1000 Genomes Project Consortium
-
Sudmant PH, et al.; 1000 Genomes Project Consortium (2015) An integrated map of structural variation in 2,504 human genomes. Nature 526(7571):75-81.
-
(2015)
Nature
, vol.526
, Issue.7571
, pp. 75-81
-
-
Sudmant, P.H.1
-
48
-
-
84904247696
-
Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing
-
Helman E, et al. (2014) Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing. Genome Res 24(7):1053-1063.
-
(2014)
Genome Res
, vol.24
, Issue.7
, pp. 1053-1063
-
-
Helman, E.1
-
49
-
-
84868032982
-
Single-neuron sequencing analysis of L1 retrotransposition and somatic mutation in the human brain
-
Evrony GD, et al. (2012) Single-neuron sequencing analysis of L1 retrotransposition and somatic mutation in the human brain. Cell 151(3):483-496.
-
(2012)
Cell
, vol.151
, Issue.3
, pp. 483-496
-
-
Evrony, G.D.1
|