CRF1 receptor-deficiency increases cocaine reward

Neuropharmacology

Volumn 117, Issue , 2017, Pages 41-48

  Contarino, Angelo ^a,c   Kitchener, Pierre ^b,c   Vallée, Monique ^b,c   Papaleo, Francesco ^d   Piazza, Pier Vincenzo ^b,c  

^a UMR 5287   (France)

^b INSTITUT FRANÇOIS MAGENDIE   (France)

^c UNIVERSITÉ DE BORDEAUX   (France)

^d ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

Author keywords

Cocaine; Corticotropin releasing factor (CRF) receptor 1; Hypothalamus pituitary adrenal (HPA) axis; Reward; Stereotypy

Indexed keywords

ANTALARMIN; COCAINE; CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; GLUCOCORTICOID RECEPTOR; CORTICOTROPIN RELEASING FACTOR RECEPTOR; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CIRCADIAN RHYTHM; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DRUG SEEKING BEHAVIOR; HIPPOCAMPUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; MOUSE; NONHUMAN; PLACE PREFERENCE; PROTEIN DEPLETION; RECEPTOR BLOCKING; STEREOTYPY; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; CONDITIONING; DOSE RESPONSE; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; REWARD;

ANIMALS; CIRCADIAN RHYTHM; COCAINE; CONDITIONING (PSYCHOLOGY); CORTICOSTERONE; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; MALE; MICE; MICE, KNOCKOUT; PYRIMIDINES; PYRROLES; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; RECEPTORS, GLUCOCORTICOID; REWARD; STEREOTYPED BEHAVIOR;

EID: 85011041151     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2017.01.024     Document Type: Article

References (56)

1. Ahima, R.S., Harlan, R.E., Charting of type II glucocorticoid receptor-like immunoreactivity in the rat central nervous system. Neuroscience 39 (1990), 579–604.
2. Bale, T.L., Vale, W.W., CRF and CRF receptors: role in stress responsivity and other behaviors. Annu. Rev. Pharmacol. Toxicol. 44 (2004), 525–557.
3. Blanchard, D.C., Blanchard, R.J., Cocaine potentiates defensive behaviors related to fear and anxiety. Neurosci. Biobehav Rev. 23 (1999), 981–991.
4. Blanchard, R.J., Hebert, M.A., Dulloog, L., Kaawaloa, N., Nishimura, O., Blanchard, D.C., Acute cocaine effects on stereotype and defense: an ethoexperimental approach. Neurosci. Biobehav Rev. 23 (1998), 179–188.
5. Bradbury, M.J., McBurnie, M.I., Denton, D.A., Lee, K.F., Vale, W.W., Modulation of urocortin-induced hypophagia and weight loss by corticotropin-releasing factor receptor 1 deficiency in mice. Endocrinology 141 (2000), 2715–2724.
6. Briand, L.A., Blendy, J.A., Molecular and genetic substrates linking stress and addiction. Brain Res. 1314 (2010), 219–234.
7. Cador, M., Dulluc, J., Mormede, P., Modulation of the locomotor response to amphetamine by corticosterone. Neuroscience 56 (1993), 981–988.
8. Contarino, A., Dellu, F., Koob, G.F., Smith, G.W., Lee, K.F., Vale, W., Gold, L.H., Reduced anxiety-like and cognitive performance in mice lacking the corticotropin-releasing factor receptor 1. Brain Res. 835 (1999), 1–9.
9. Contarino, A., Dellu, F., Koob, G.F., Smith, G.W., Lee, K.F., Vale, W.W., Gold, L.H., Dissociation of locomotor activation and suppression of food intake induced by CRF in CRFR1-deficient mice. Endocrinology 141 (2000), 2698–2702.
10. Contarino, A., Gold, L.H., Targeted mutations of the corticotropin-releasing factor system: effects on physiology and behavior. Neuropeptides 36 (2002), 103–116.
11. Contarino, A., Papaleo, F., The corticotropin-releasing factor receptor-1 pathway mediates the negative affective states of opiate withdrawal. Proc. Natl. Acad. Sci. U. S. A. 102 (2005), 18649–18654 Epub 12005 Dec 18648.
12. de Jong, I.E., Oitzl, M.S., de Kloet, E.R., Adrenalectomy prevents behavioural sensitisation of mice to cocaine in a genotype-dependent manner. Behav. Brain Res. 177 (2007), 329–339.
13. de Kloet, E.R., Hormones, brain and stress. Endocr. Regul. 37 (2003), 51–68.
14. Deroche, V., Marinelli, M., Le Moal, M., Piazza, P.V., Glucocorticoids and behavioral effects of psychostimulants. II: cocaine intravenous self-administration and reinstatement depend on glucocorticoid levels. J. Pharmacol. Exp. Ther. 281 (1997), 1401–1407.
15. Erb, S., Shaham, Y., Stewart, J., The role of corticotropin-releasing factor and corticosterone in stress- and cocaine-induced relapse to cocaine seeking in rats. J. Neurosci. 18 (1998), 5529–5536.
16. Fuxe, K., Wikstrom, A.C., Okret, S., Agnati, L.F., Harfstrand, A., Yu, Z.Y., Granholm, L., Zoli, M., Vale, W., Gustafsson, J.A., Mapping of glucocorticoid receptor immunoreactive neurons in the rat tel- and diencephalon using a monoclonal antibody against rat liver glucocorticoid receptor. Endocrinology 117 (1985), 1803–1812.
17. Gawin, F.H., Cocaine addiction: psychology and neurophysiology. Science 251 (1991), 1580–1586.
18. Grant, B.F., Harford, T.C., Concurrent and simultaneous use of alcohol with cocaine: results of national survey. Drug Alcohol Depend. 25 (1990), 97–104.
19. Haile, C.N., GrandPre, T., Kosten, T.A., Chronic unpredictable stress, but not chronic predictable stress, enhances the sensitivity to the behavioral effects of cocaine in rats. Psychopharmacol. Berl. 154 (2001), 213–220.
20. Hauger, R.L., Grigoriadis, D.E., Dallman, M.F., Plotsky, P.M., Vale, W.W., Dautzenberg, F.M., International Union of Pharmacology. XXXVI. Current status of the nomenclature for receptors for corticotropin-releasing factor and their ligands. Pharmacol. Rev. 55 (2003), 21–26.
21. Herman, J.P., Spencer, R., Regulation of hippocampal glucocorticoid receptor gene transcription and protein expression in vivo. J. Neurosci. 18 (1998), 7462–7473.
22. Holly, E.N., Boyson, C.O., Montagud-Romero, S., Stein, D.J., Gobrogge, K.L., DeBold, J.F., Miczek, K.A., Episodic social stress-escalated cocaine self-administration: role of phasic and tonic corticotropin releasing factor in the anterior and posterior ventral tegmental area. J. Neurosci. 36 (2016), 4093–4105.
23. Howes, S.R., Dalley, J.W., Morrison, C.H., Robbins, T.W., Everitt, B.J., Leftward shift in the acquisition of cocaine self-administration in isolation-reared rats: relationship to extracellular levels of dopamine, serotonin and glutamate in the nucleus accumbens and amygdala-striatal FOS expression. Psychopharmacol. Berl. 151 (2000), 55–63.
24. Kitchener, P., Di Blasi, F., Borrelli, E., Piazza, P.V., Differences between brain structures in nuclear translocation and DNA binding of the glucocorticoid receptor during stress and the circadian cycle. Eur. J. Neurosci. 19 (2004), 1837–1846.
25. Koob, G.F., A role for brain stress systems in addiction. Neuron 59 (2008), 11–34.
26. Laemmli, U.K., Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970), 680–685.
27. Lu, L., Liu, Z., Huang, M., Zhang, Z., Dopamine-dependent responses to cocaine depend on corticotropin-releasing factor receptor subtypes. J. Neurochem. 84 (2003), 1378–1386.
28. Maj, M., Turchan, J., Smialowska, M., Przewlocka, B., Morphine and cocaine influence on CRF biosynthesis in the rat central nucleus of amygdala. Neuropeptides 37 (2003), 105–110.
29. Marinelli, M., Rouge-Pont, F., Deroche, V., Barrot, M., De Jesus-Oliveira, C., Le Moal, M., Piazza, P.V., Glucocorticoids and behavioral effects of psychostimulants. I: locomotor response to cocaine depends on basal levels of glucocorticoids. J. Pharmacol. Exp. Ther. 281 (1997), 1392–1400.
30. Marrow, L., Statham, A., Overton, P.G., Brain, P.F., Clark, D., The corticosteroid synthesis inhibitor metyrapone markedly enhances the behavioural effects of d-amphetamine. Addict. Biol. 4 (1999), 89–92.
31. Mendelson, J.H., Mello, N.K., Management of cocaine abuse and dependence. N. Engl. J. Med. 334 (1996), 965–972.
32. Morisot, N., Millan, M.J., Contarino, A., CRF1 receptor-deficiency induces anxiety-like vulnerability to cocaine. Psychopharmacol. Berl. 231 (2014), 3965–3972.
33. Papaleo, F., Ghozland, S., Ingallinesi, M., Roberts, A.J., Koob, G.F., Contarino, A., Disruption of the CRF(2) receptor pathway decreases the somatic expression of opiate withdrawal. Neuropsychopharmacology 33 (2008), 2878–2887 Epub 2008 Feb 2820.
34. Papaleo, F., Kitchener, P., Contarino, A., Disruption of the CRF/CRF1 receptor stress system exacerbates the somatic signs of opiate withdrawal. Neuron 53 (2007), 577–589.
35. Piazza, P.V., Le Moal, M., The role of stress in drug self-administration. Trends Pharmacol. Sci. 19 (1998), 67–74.
36. Richter, R.M., Pich, E.M., Koob, G.F., Weiss, F., Sensitization of cocaine-stimulated increase in extracellular levels of corticotropin-releasing factor from the rat amygdala after repeated administration as determined by intracranial microdialysis. Neurosci. Lett. 187 (1995), 169–172.
37. Rivier, C., Lee, S., Stimulatory effect of cocaine on ACTH secretion: role of the hypothalamus. Mol. Cell Neurosci. 5 (1994), 189–195.
38. Rivier, C., Vale, W., Cocaine stimulates adrenocorticotropin (ACTH) secretion through a corticotropin-releasing factor (CRF)-mediated mechanism. Brain Res. 422 (1987), 403–406.
39. Rodaros, D., Caruana, D.A., Amir, S., Stewart, J., Corticotropin-releasing factor projections from limbic forebrain and paraventricular nucleus of the hypothalamus to the region of the ventral tegmental area. Neuroscience 150 (2007), 8–13.
40. Rogerio, R., Takahashi, R.N., Anxiogenic properties of cocaine in the rat evaluated with the elevated plus-maze. Pharmacol. Biochem. Behav. 43 (1992), 631–633.
41. Russo, S.J., Jenab, S., Fabian, S.J., Festa, E.D., Kemen, L.M., Quinones-Jenab, V., Sex differences in the conditioned rewarding effects of cocaine. Brain Res. 970 (2003), 214–220.
42. Sanchez, E.R., Heat shock induces translocation to the nucleus of the unliganded glucocorticoid receptor. J. Biol. Chem. 267 (1992), 17–20.
43. Sarnyai, Z., Biro, E., Penke, B., Telegdy, G., The cocaine-induced elevation of plasma corticosterone is mediated by endogenous corticotropin-releasing factor (CRF) in rats. Brain Res. 589 (1992), 154–156.
44. Smith, G.W., Aubry, J.M., Dellu, F., Contarino, A., Bilezikjian, L.M., Gold, L.H., Chen, R., Marchuk, Y., Hauser, C., Bentley, C.A., Sawchenko, P.E., Koob, G.F., Vale, W., Lee, K.F., Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development. Neuron 20 (1998), 1093–1102.
45. Spangler, R., Zhou, Y., Schlussman, S.D., Ho, A., Kreek, M.J., Behavioral stereotypies induced by ”binge' cocaine administration are independent of drug-induced increases in corticosterone levels. Behav. Brain Res. 86 (1997), 201–204.
46. Specio, S.E., Wee, S., O'Dell, L.E., Boutrel, B., Zorrilla, E.P., Koob, G.F., CRF(1) receptor antagonists attenuate escalated cocaine self-administration in rats. Psychopharmacol. Berl. 196 (2008), 473–482 Epub 2007 Oct 2030.
47. Suzuki, T., Sugano, Y., Funada, M., Misawa, M., Adrenalectomy potentiates the morphine–but not cocaine-induced place preference in rats. Life Sci. 56 (1995), PL339–344.
48. Timpl, P., Spanagel, R., Sillaber, I., Kresse, A., Reul, J.M., Stalla, G.K., Blanquet, V., Steckler, T., Holsboer, F., Wurst, W., Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1. Nat. Genet. 19 (1998), 162–166.
49. Tzschentke, T.M., Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade. Addict. Biol. 12 (2007), 227–462.
50. Vandevyver, S., Dejager, L., Libert, C., On the trail of the glucocorticoid receptor: into the nucleus and back. Traffic 13 (2012), 364–374.
51. Webster, E.L., Lewis, D.B., Torpy, D.J., Zachman, E.K., Rice, K.C., Chrousos, G.P., In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation. Endocrinology 137 (1996), 5747–5750.
52. Wei, Q., Fentress, H.M., Hoversten, M.T., Zhang, L., Hebda-Bauer, E.K., Watson, S.J., Seasholtz, A.F., Akil, H., Early-life forebrain glucocorticoid receptor overexpression increases anxiety behavior and cocaine sensitization. Biol. Psychiatry 71 (2012), 224–231.
53. Wei, Q., Lu, X.Y., Liu, L., Schafer, G., Shieh, K.R., Burke, S., Robinson, T.E., Watson, S.J., Seasholtz, A.F., Akil, H., Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability. Proc. Natl. Acad. Sci. U. S. A. 101 (2004), 11851–11856 Epub 12004 Jul 11827.
54. Williamson, S., Gossop, M., Powis, B., Griffiths, P., Fountain, J., Strang, J., Adverse effects of stimulant drugs in a community sample of drug users. Drug Alcohol Depend. 44 (1997), 87–94.
55. Yang, X.M., Gorman, A.L., Dunn, A.J., Goeders, N.E., Anxiogenic effects of acute and chronic cocaine administration: neurochemical and behavioral studies. Pharmacol. Biochem. Behav. 41 (1992), 643–650.
56. Zorrilla, E.P., Koob, G.F., The therapeutic potential of CRF1 antagonists for anxiety. Expert Opin. Investig. Drugs 13 (2004), 799–828.