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Volumn 13, Issue 1, 2017, Pages

Fighting Ebola: A Window for Vaccine Re-evaluation?

Author keywords

[No Author keywords available]

Indexed keywords

EBOLA VACCINE; MUCIN;

EID: 85011003461     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1006037     Document Type: Article
Times cited : (14)

References (38)
  • 1
    • 84982211867 scopus 로고    scopus 로고
    • Ebola virus disease candidate vaccines under evaluation in clinical trials
    • 7160784, ().: –
    • Martins KA, Jahrling PB, Bavari S, Kuhn JH, (2016) Ebola virus disease candidate vaccines under evaluation in clinical trials. Expert Rev Vaccines15: 1101–1112. doi: 10.1080/14760584.2016.118756627160784
    • (2016) Expert Rev Vaccines , vol.15 , pp. 1101-1112
    • Martins, K.A.1    Jahrling, P.B.2    Bavari, S.3    Kuhn, J.H.4
  • 4
    • 79955387781 scopus 로고    scopus 로고
    • Recombinant adenovirus serotype 26 (Ad26) and Ad35 vaccine vectors bypass immunity to Ad5 and protect nonhuman primates against ebolavirus challenge
    • 1325402,. ().: –
    • Geisbert TW, Bailey M, Hensley L, Asiedu C, Geisbert J, et al. (2011) Recombinant adenovirus serotype 26 (Ad26) and Ad35 vaccine vectors bypass immunity to Ad5 and protect nonhuman primates against ebolavirus challenge. J Virol85: 4222–4233. doi: 10.1128/JVI.02407-1021325402
    • (2011) J Virol , vol.85 , pp. 4222-4233
    • Geisbert, T.W.1    Bailey, M.2    Hensley, L.3    Asiedu, C.4    Geisbert, J.5
  • 5
    • 84907263544 scopus 로고    scopus 로고
    • Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge
    • 5194571,. ().: –
    • Stanley DA, Honko AN, Asiedu C, Trefry JC, Lau-Kilby AW, et al. (2014) Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge. Nat Med20: 1126–1129. doi: 10.1038/nm.370225194571
    • (2014) Nat Med , vol.20 , pp. 1126-1129
    • Stanley, D.A.1    Honko, A.N.2    Asiedu, C.3    Trefry, J.C.4    Lau-Kilby, A.W.5
  • 6
    • 84959245846 scopus 로고    scopus 로고
    • Safety and immunogenicity of a chimpanzee adenovirus-vectored Ebola vaccine in healthy adults: a randomised, double-blind, placebo-controlled, dose-finding, phase 1/2a study
    • 6725450,. ().: –
    • De Santis O, Audran R, Pothin E, Warpelin-Decrausaz L, Vallotton L, et al. (2016) Safety and immunogenicity of a chimpanzee adenovirus-vectored Ebola vaccine in healthy adults: a randomised, double-blind, placebo-controlled, dose-finding, phase 1/2a study. Lancet Infect Dis16: 311–320. doi: 10.1016/S1473-3099(15)00486-726725450
    • (2016) Lancet Infect Dis , vol.16 , pp. 311-320
    • De Santis, O.1    Audran, R.2    Pothin, E.3    Warpelin-Decrausaz, L.4    Vallotton, L.5
  • 7
    • 84964335436 scopus 로고    scopus 로고
    • Safety and Immunogenicity of Novel Adenovirus Type 26- and Modified Vaccinia Ankara-Vectored Ebola Vaccines: A Randomized Clinical Trial
    • 7092831,. ().: –
    • Milligan ID, Gibani MM, Sewell R, Clutterbuck EA, Campbell D, et al. (2016) Safety and Immunogenicity of Novel Adenovirus Type 26- and Modified Vaccinia Ankara-Vectored Ebola Vaccines: A Randomized Clinical Trial. JAMA315: 1610–1623. doi: 10.1001/jama.2016.421827092831
    • (2016) JAMA , vol.315 , pp. 1610-1623
    • Milligan, I.D.1    Gibani, M.M.2    Sewell, R.3    Clutterbuck, E.A.4    Campbell, D.5
  • 8
    • 84940952795 scopus 로고    scopus 로고
    • Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial
    • 6248676,. ().: –
    • Henao-Restrepo AM, Longini IM, Egger M, Dean NE, Edmunds WJ, et al. (2015) Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial. Lancet386: 857–866. doi: 10.1016/S0140-6736(15)61117-526248676
    • (2015) Lancet , vol.386 , pp. 857-866
    • Henao-Restrepo, A.M.1    Longini, I.M.2    Egger, M.3    Dean, N.E.4    Edmunds, W.J.5
  • 9
    • 84964969174 scopus 로고    scopus 로고
    • Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe
    • 5830326,. ().: –
    • Agnandji ST, Huttner A, Zinser ME, Njuguna P, Dahlke C, et al. (2016) Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe. N Engl J Med374: 1647–1660. doi: 10.1056/NEJMoa150292425830326
    • (2016) N Engl J Med , vol.374 , pp. 1647-1660
    • Agnandji, S.T.1    Huttner, A.2    Zinser, M.E.3    Njuguna, P.4    Dahlke, C.5
  • 10
    • 84955264022 scopus 로고    scopus 로고
    • First-in-Human Evaluation of the Safety and Immunogenicity of a Recombinant Vesicular Stomatitis Virus Human Immunodeficiency Virus-1 gag Vaccine (HVTN 090)
    • 6199949,. ().:
    • Fuchs JD, Frank I, Elizaga ML, Allen M, Frahm N, et al. (2015) First-in-Human Evaluation of the Safety and Immunogenicity of a Recombinant Vesicular Stomatitis Virus Human Immunodeficiency Virus-1 gag Vaccine (HVTN 090). Open Forum Infect Dis2: ofv082. doi: 10.1093/ofid/ofv08226199949
    • (2015) Open Forum Infect Dis , vol.2 , pp. ofv082
    • Fuchs, J.D.1    Frank, I.2    Elizaga, M.L.3    Allen, M.4    Frahm, N.5
  • 11
    • 0033831191 scopus 로고    scopus 로고
    • Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injury
    • 0932225,. ().: –
    • Yang ZY, Duckers HJ, Sullivan NJ, Sanchez A, Nabel EG, et al. (2000) Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injury. Nat Med6: 886–889. doi: 10.1038/7864510932225
    • (2000) Nat Med , vol.6 , pp. 886-889
    • Yang, Z.Y.1    Duckers, H.J.2    Sullivan, N.J.3    Sanchez, A.4    Nabel, E.G.5
  • 12
    • 72849134026 scopus 로고    scopus 로고
    • Interaction between Ebola virus glycoprotein and host toll-like receptor 4 leads to induction of proinflammatory cytokines and SOCS1
    • 9846529, ().: –
    • Okumura A, Pitha PM, Yoshimura A, Harty RN, (2010) Interaction between Ebola virus glycoprotein and host toll-like receptor 4 leads to induction of proinflammatory cytokines and SOCS1. J Virol84: 27–33. doi: 10.1128/JVI.01462-0919846529
    • (2010) J Virol , vol.84 , pp. 27-33
    • Okumura, A.1    Pitha, P.M.2    Yoshimura, A.3    Harty, R.N.4
  • 13
    • 84941247956 scopus 로고    scopus 로고
    • Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity
    • 6355031,. ().:
    • Modhiran N, Watterson D, Muller DA, Panetta AK, Sester DP, et al. (2015) Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity. Sci Transl Med7: 304ra142. doi: 10.1126/scitranslmed.aaa386326355031
    • (2015) Sci Transl Med , vol.7 , pp. 304ra142
    • Modhiran, N.1    Watterson, D.2    Muller, D.A.3    Panetta, A.K.4    Sester, D.P.5
  • 14
    • 84939571191 scopus 로고    scopus 로고
    • Treatment of Ebola virus infections with inhibitors of TLR4
    • 6003830, ().: –
    • Denner J, (2015) Treatment of Ebola virus infections with inhibitors of TLR4. Med Hypotheses85: 253–257. doi: 10.1016/j.mehy.2015.05.00926003830
    • (2015) Med Hypotheses , vol.85 , pp. 253-257
    • Denner, J.1
  • 15
    • 84937022260 scopus 로고    scopus 로고
    • Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol
    • 6158910,. ().:
    • Hacke M, Bjorkholm P, Hellwig A, Himmels P, de Almodovar CR, et al. (2015) Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol. Nat Commun6: 7688. doi: 10.1038/ncomms868826158910
    • (2015) Nat Commun , vol.6 , pp. 7688
    • Hacke, M.1    Bjorkholm, P.2    Hellwig, A.3    Himmels, P.4    de Almodovar, C.R.5
  • 16
    • 2942526839 scopus 로고    scopus 로고
    • Ectodomain shedding of the glycoprotein GP of Ebola virus
    • 5103332,. ().: –
    • Dolnik O, Volchkova V, Garten W, Carbonnelle C, Becker S, et al. (2004) Ectodomain shedding of the glycoprotein GP of Ebola virus. EMBO J23: 2175–2184. doi: 10.1038/sj.emboj.760021915103332
    • (2004) EMBO J , vol.23 , pp. 2175-2184
    • Dolnik, O.1    Volchkova, V.2    Garten, W.3    Carbonnelle, C.4    Becker, S.5
  • 17
    • 84912058948 scopus 로고    scopus 로고
    • Shed GP of Ebola virus triggers immune activation and increased vascular permeability
    • 5412102, ().:
    • Escudero-Perez B, Volchkova VA, Dolnik O, Lawrence P, Volchkov VE, (2014) Shed GP of Ebola virus triggers immune activation and increased vascular permeability. PLoS Pathog10: e1004509. doi: 10.1371/journal.ppat.100450925412102
    • (2014) PLoS Pathog , vol.10 , pp. e1004509
    • Escudero-Perez, B.1    Volchkova, V.A.2    Dolnik, O.3    Lawrence, P.4    Volchkov, V.E.5
  • 18
    • 84943327908 scopus 로고    scopus 로고
    • Shedding of Ebola Virus Surface Glycoprotein Is a Mechanism of Self-regulation of Cellular Cytotoxicity and Has a Direct Effect on Virus Infectivity
    • Dolnik O, Volchkova VA, Escudero-Perez B, Lawrence P, Klenk HD, et al. (2015) Shedding of Ebola Virus Surface Glycoprotein Is a Mechanism of Self-regulation of Cellular Cytotoxicity and Has a Direct Effect on Virus Infectivity. J Infect Dis212Suppl 2: S322–328.
    • (2015) J Infect Dis , vol.212 , pp. S322-328
    • Dolnik, O.1    Volchkova, V.A.2    Escudero-Perez, B.3    Lawrence, P.4    Klenk, H.D.5
  • 19
    • 80054735134 scopus 로고    scopus 로고
    • Impact of Ebola mucin-like domain on antiglycoprotein antibody responses induced by Ebola virus-like particles
    • Martinez O, Tantral L, Mulherkar N, Chandran K, Basler CF, (2011) Impact of Ebola mucin-like domain on antiglycoprotein antibody responses induced by Ebola virus-like particles. J Infect Dis204Suppl 3: S825–832.
    • (2011) J Infect Dis , vol.204 , pp. S825-832
    • Martinez, O.1    Tantral, L.2    Mulherkar, N.3    Chandran, K.4    Basler, C.F.5
  • 20
    • 72849133481 scopus 로고    scopus 로고
    • A forward genetic strategy reveals destabilizing mutations in the Ebolavirus glycoprotein that alter its protease dependence during cell entry
    • 9846533, ().: –
    • Wong AC, Sandesara RG, Mulherkar N, Whelan SP, Chandran K, (2010) A forward genetic strategy reveals destabilizing mutations in the Ebolavirus glycoprotein that alter its protease dependence during cell entry. J Virol84: 163–175. doi: 10.1128/JVI.01832-0919846533
    • (2010) J Virol , vol.84 , pp. 163-175
    • Wong, A.C.1    Sandesara, R.G.2    Mulherkar, N.3    Whelan, S.P.4    Chandran, K.5
  • 21
    • 84959458245 scopus 로고    scopus 로고
    • Notes from the Field: Circulating Vaccine-Derived Poliovirus Outbreaks—Five Countries, 2014–2015
    • 6866942, ().: –
    • Morales M, Nnadi CD, Tangermann RH, Wassilak SG, (2016) Notes from the Field: Circulating Vaccine-Derived Poliovirus Outbreaks—Five Countries, 2014–2015. MMWR Morb Mortal Wkly Rep65: 128–129. doi: 10.15585/mmwr.mm6505a526866942
    • (2016) MMWR Morb Mortal Wkly Rep , vol.65 , pp. 128-129
    • Morales, M.1    Nnadi, C.D.2    Tangermann, R.H.3    Wassilak, S.G.4
  • 22
    • 2342455182 scopus 로고    scopus 로고
    • Properties of replication-competent vesicular stomatitis virus vectors expressing glycoproteins of filoviruses and arenaviruses
    • 5113924,. ().: –
    • Garbutt M, Liebscher R, Wahl-Jensen V, Jones S, Moller P, et al. (2004) Properties of replication-competent vesicular stomatitis virus vectors expressing glycoproteins of filoviruses and arenaviruses. J Virol78: 5458–5465. doi: 10.1128/JVI.78.10.5458-5465.200415113924
    • (2004) J Virol , vol.78 , pp. 5458-5465
    • Garbutt, M.1    Liebscher, R.2    Wahl-Jensen, V.3    Jones, S.4    Moller, P.5
  • 23
    • 85010982266 scopus 로고    scopus 로고
    • In: ClinicalTrials.gov [Internet].:. - [cited 2016 Oct 28]. Bethesda (MD) National Library of Medicine (US
    • GlaxoSmithKlineStudy to Evaluate the Safety and Immunogenicity of a Candidate Ebola Vaccine in Children. In: ClinicalTrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000- [cited 2016 Oct 28]. https://clinicaltrials.gov/ct2/show/NCT02548078.
    • (2000) Study to Evaluate the Safety and Immunogenicity of a Candidate Ebola Vaccine in Children
  • 25
    • 84925436702 scopus 로고    scopus 로고
    • Emergency postexposure vaccination with vesicular stomatitis virus-vectored Ebola vaccine after needlestick
    • 5742465,. ().: –
    • Lai L, Davey R, Beck A, Xu Y, Suffredini AF, et al. (2015) Emergency postexposure vaccination with vesicular stomatitis virus-vectored Ebola vaccine after needlestick. JAMA313: 1249–1255. doi: 10.1001/jama.2015.199525742465
    • (2015) JAMA , vol.313 , pp. 1249-1255
    • Lai, L.1    Davey, R.2    Beck, A.3    Xu, Y.4    Suffredini, A.F.5
  • 26
    • 84990936358 scopus 로고    scopus 로고
    • Efficacy of Vesicular Stomatitis Virus-Ebola Virus Postexposure Treatment in Rhesus Macaques Infected With Ebola Virus Makona
    • 7496978,. ().: –
    • Marzi A, Hanley PW, Haddock E, Martellaro C, Kobinger G, et al. (2016) Efficacy of Vesicular Stomatitis Virus-Ebola Virus Postexposure Treatment in Rhesus Macaques Infected With Ebola Virus Makona. J Infect Dis214: S360–S366. doi: 10.1093/infdis/jiw21827496978
    • (2016) J Infect Dis , vol.214 , pp. S360-S366
    • Marzi, A.1    Hanley, P.W.2    Haddock, E.3    Martellaro, C.4    Kobinger, G.5
  • 27
    • 43949115183 scopus 로고    scopus 로고
    • Recombinant vesicular stomatitis virus vector mediates postexposure protection against Sudan Ebola hemorrhagic fever in nonhuman primates
    • 8385248,. ().: –
    • Geisbert TW, Daddario-DiCaprio KM, Williams KJ, Geisbert JB, Leung A, et al. (2008) Recombinant vesicular stomatitis virus vector mediates postexposure protection against Sudan Ebola hemorrhagic fever in nonhuman primates. J Virol82: 5664–5668. doi: 10.1128/JVI.00456-0818385248
    • (2008) J Virol , vol.82 , pp. 5664-5668
    • Geisbert, T.W.1    Daddario-DiCaprio, K.M.2    Williams, K.J.3    Geisbert, J.B.4    Leung, A.5
  • 28
    • 84954245042 scopus 로고    scopus 로고
    • Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1
    • 6771495,. ().: –
    • Wang H, Shi Y, Song J, Qi J, Lu G, et al. (2016) Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1. Cell164: 258–268. doi: 10.1016/j.cell.2015.12.04426771495
    • (2016) Cell , vol.164 , pp. 258-268
    • Wang, H.1    Shi, Y.2    Song, J.3    Qi, J.4    Lu, G.5
  • 29
    • 84981214211 scopus 로고    scopus 로고
    • Structures of Ebola virus GP and sGP in complex with therapeutic antibodies
    • 7562261,. ().:
    • Pallesen J, Murin CD, de Val N, Cottrell CA, Hastie KM, et al. (2016) Structures of Ebola virus GP and sGP in complex with therapeutic antibodies. Nat Microbiol1: 16128. doi: 10.1038/nmicrobiol.2016.12827562261
    • (2016) Nat Microbiol , vol.1 , pp. 16128
    • Pallesen, J.1    Murin, C.D.2    de Val, N.3    Cottrell, C.A.4    Hastie, K.M.5
  • 30
    • 84969961924 scopus 로고    scopus 로고
    • Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection
    • 7238017,. ().: –
    • Gong X, Qian H, Zhou X, Wu J, Wan T, et al. (2016) Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection. Cell165: 1467–1478. doi: 10.1016/j.cell.2016.05.02227238017
    • (2016) Cell , vol.165 , pp. 1467-1478
    • Gong, X.1    Qian, H.2    Zhou, X.3    Wu, J.4    Wan, T.5
  • 31
    • 84960154024 scopus 로고    scopus 로고
    • Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies
    • 6908579,. ().: –
    • Bornholdt ZA, Ndungo E, Fusco ML, Bale S, Flyak AI, et al. (2016) Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies. MBio7: e02154–02115. doi: 10.1128/mBio.02154-1526908579
    • (2016) MBio , vol.7 , pp. e02115-e02154
    • Bornholdt, Z.A.1    Ndungo, E.2    Fusco, M.L.3    Bale, S.4    Flyak, A.I.5
  • 32
    • 84959351355 scopus 로고    scopus 로고
    • Structural and molecular basis for Ebola virus neutralization by protective human antibodies
    • 6917592,. ().: –
    • Misasi J, Gilman MS, Kanekiyo M, Gui M, Cagigi A, et al. (2016) Structural and molecular basis for Ebola virus neutralization by protective human antibodies. Science351: 1343–1346. doi: 10.1126/science.aad611726917592
    • (2016) Science , vol.351 , pp. 1343-1346
    • Misasi, J.1    Gilman, M.S.2    Kanekiyo, M.3    Gui, M.4    Cagigi, A.5
  • 33
    • 84960400876 scopus 로고    scopus 로고
    • Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak
    • 6912366,. ().: –
    • Bornholdt ZA, Turner HL, Murin CD, Li W, Sok D, et al. (2016) Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak. Science351: 1078–1083. doi: 10.1126/science.aad578826912366
    • (2016) Science , vol.351 , pp. 1078-1083
    • Bornholdt, Z.A.1    Turner, H.L.2    Murin, C.D.3    Li, W.4    Sok, D.5
  • 36
    • 84978437369 scopus 로고    scopus 로고
    • Toremifene interacts with and destabilizes the Ebola virus glycoprotein
    • 7362232,. ().: –
    • Zhao Y, Ren J, Harlos K, Jones DM, Zeltina A, et al. (2016) Toremifene interacts with and destabilizes the Ebola virus glycoprotein. Nature535: 169–172. doi: 10.1038/nature1861527362232
    • (2016) Nature , vol.535 , pp. 169-172
    • Zhao, Y.1    Ren, J.2    Harlos, K.3    Jones, D.M.4    Zeltina, A.5
  • 37
    • 84906346444 scopus 로고    scopus 로고
    • Spatial localization of the Ebola virus glycoprotein mucin-like domain determined by cryo-electron tomography
    • 5008940,. ().: –
    • Tran EE, Simmons JA, Bartesaghi A, Shoemaker CJ, Nelson E, et al. (2014) Spatial localization of the Ebola virus glycoprotein mucin-like domain determined by cryo-electron tomography. J Virol88: 10958–10962. doi: 10.1128/JVI.00870-1425008940
    • (2014) J Virol , vol.88 , pp. 10958-10962
    • Tran, E.E.1    Simmons, J.A.2    Bartesaghi, A.3    Shoemaker, C.J.4    Nelson, E.5
  • 38
    • 84914127561 scopus 로고    scopus 로고
    • Structures of protective antibodies reveal sites of vulnerability on Ebola virus
    • 5404321,. ().: –
    • Murin CD, Fusco ML, Bornholdt ZA, Qiu X, Olinger GG, et al. (2014) Structures of protective antibodies reveal sites of vulnerability on Ebola virus. Proc Natl Acad Sci U S A111: 17182–17187. doi: 10.1073/pnas.141416411125404321
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 17182-17187
    • Murin, C.D.1    Fusco, M.L.2    Bornholdt, Z.A.3    Qiu, X.4    Olinger, G.G.5


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