Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak

Science

Volumn 351, Issue 6277, 2016, Pages 1078-1083

  Bornholdt, Zachary A ^a   Turner, Hannah L ^a   Murin, Charles D ^a   Li, Wen ^b   Sok, Devin ^a   Souders, Colby A ^c   Piper, Ashley E ^d   Goff, Arthur ^d   Shamblin, Joshua D ^d   Wollen, Suzanne E ^d   Sprague, Thomas R ^d   Fusco, Marnie L ^a   Pommert, Kathleen B J ^a   Cavacini, Lisa A ^c   Smith, Heidi L ^c   Klempner, Mark ^c   Reimann, Keith A ^c   Krauland, Eric ^b   Gerngross, Tillman U ^b   Wittrup, Karl D ^b   Saphire, Erica Ollmann ^a   Burton, Dennis R ^a,e   Glass, Pamela J ^d   Ward, Andrew B ^a   Walker, Laura M ^b   more..

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Adimab Inc   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^e HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; VIRUS GLYCOPROTEIN; ANTIGEN ANTIBODY COMPLEX; EBOLA VACCINE; ENVELOPE GLYCOPROTEIN, EBOLA VIRUS; VIRUS ANTIBODY; VIRUS ENVELOPE PROTEIN;

ANTIBODY; CELLS AND CELL COMPONENTS; DISEASE TREATMENT; SURVIVAL; VACCINE; VIRAL DISEASE; VULNERABILITY;

ANTIBODY ISOLATION; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; COMPARATIVE STUDY; CONFORMATION; CONTROLLED STUDY; CROSS REACTION; CRYSTAL STRUCTURE; EBOLAVIRUS; ELECTRON MICROSCOPY; EPIDEMIC; FLOW CYTOMETRY; HUMAN; INTERFEROMETRY; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SURVIVAL RATE; TITRIMETRY; VIRUS PLAQUE; ANIMAL; ANTIBODY PRODUCTION; ANTIGEN ANTIBODY COMPLEX; CHEMISTRY; DEMOCRATIC REPUBLIC CONGO; DONOR; HEMORRHAGIC FEVER, EBOLA; IMMUNOLOGY; ISOLATION AND PURIFICATION; MOUSE; PASSIVE IMMUNIZATION; SURVIVOR; VIRION;

EBOLA VIRUS; MUS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ANTIBODY FORMATION; ANTIGEN-ANTIBODY COMPLEX; DEMOCRATIC REPUBLIC OF THE CONGO; DISEASE OUTBREAKS; EBOLA VACCINES; EBOLAVIRUS; HEMORRHAGIC FEVER, EBOLA; HUMANS; IMMUNIZATION, PASSIVE; MICE; SURVIVORS; TISSUE DONORS; VIRAL ENVELOPE PROTEINS; VIRION;

EID: 84960400876     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aad5788     Document Type: Article

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