-
1
-
-
34547661993
-
Triplenegative breast cancer: Clinical features and patterns of recurrence
-
Dent R, Trudeau M, Pritchard KI, Hanna WM, Kahn HK, Sawka CA et al. Triplenegative breast cancer: clinical features and patterns of recurrence. Clin Cancer Res 2007; 13(Pt 1): 4429-4434.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4429-4434
-
-
Dent, R.1
Trudeau, M.2
Pritchard, K.I.3
Hanna, W.M.4
Kahn, H.K.5
Sawka, C.A.6
-
2
-
-
41649102048
-
Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer
-
Liedtke C, Mazouni C, Hess KR, Andre F, Tordai A, Mejia JA et al. Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer. J Clin Oncol 2008; 26: 1275-1281.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1275-1281
-
-
Liedtke, C.1
Mazouni, C.2
Hess, K.R.3
Andre, F.4
Tordai, A.5
Mejia, J.A.6
-
3
-
-
13044304179
-
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
-
Perou CM, Jeffrey SS, van de Rijn M, Rees CA, Eisen MB, Ross DT et al. Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc Natl Acad Sci USA 1999; 96: 9212-9217.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 9212-9217
-
-
Perou, C.M.1
Jeffrey, S.S.2
Van De Rijn, M.3
Rees, C.A.4
Eisen, M.B.5
Ross, D.T.6
-
4
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA et al. Molecular portraits of human breast tumours. Nature 2000; 406: 747-752.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
Van De Rijn, M.4
Jeffrey, S.S.5
Rees, C.A.6
-
5
-
-
33745834662
-
Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: Gene expression analyses across three different platforms
-
Sorlie T, Wang Y, Xiao C, Johnsen H, Naume B, Samaha RR et al. Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms. BMC Genomics 2006; 7: 127.
-
(2006)
BMC Genomics
, vol.7
, pp. 127
-
-
Sorlie, T.1
Wang, Y.2
Xiao, C.3
Johnsen, H.4
Naume, B.5
Samaha, R.R.6
-
6
-
-
84870312288
-
A pathway-based classification of breast cancer integrating data on differentially expressed genes, copy number variations and microRNA target genes
-
Eo HS, Heo JY, Choi Y, Hwang Y, Choi HS. A pathway-based classification of breast cancer integrating data on differentially expressed genes, copy number variations and microRNA target genes. Mol Cells 2012; 34: 393-398.
-
(2012)
Mol Cells
, vol.34
, pp. 393-398
-
-
Eo, H.S.1
Heo, J.Y.2
Choi, Y.3
Hwang, Y.4
Choi, H.S.5
-
7
-
-
31144459985
-
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
-
Bild AH, Yao G, Chang JT, Wang Q, Potti A, Chasse D et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature 2006; 439: 353-357.
-
(2006)
Nature
, vol.439
, pp. 353-357
-
-
Bild, A.H.1
Yao, G.2
Chang, J.T.3
Wang, Q.4
Potti, A.5
Chasse, D.6
-
8
-
-
0035949684
-
Predicting the clinical status of human breast cancer by using gene expression profiles
-
West M, Blanchette C, Dressman H, Huang E, Ishida S, Spang R et al. Predicting the clinical status of human breast cancer by using gene expression profiles. Proc Natl Acad Sci USA 2001; 98: 11462-11467.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11462-11467
-
-
West, M.1
Blanchette, C.2
Dressman, H.3
Huang, E.4
Ishida, S.5
Spang, R.6
-
9
-
-
77951083686
-
A pathwaybased classification of human breast cancer
-
Gatza ML, Lucas JE, Barry WT, Kim JW, Wang Q, Crawford MD et al. A pathwaybased classification of human breast cancer. Proc Natl Acad Sci USA 2010; 107: 6994-6999.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 6994-6999
-
-
Gatza, M.L.1
Lucas, J.E.2
Barry, W.T.3
Kim, J.W.4
Wang, Q.5
Crawford, M.D.6
-
10
-
-
84890470353
-
HER2/Neu tumorigenesis and metastasis is regulated by E2F activator transcription factors
-
Andrechek ER. HER2/Neu tumorigenesis and metastasis is regulated by E2F activator transcription factors. Oncogene 2015; 34: 217-225.
-
(2015)
Oncogene
, vol.34
, pp. 217-225
-
-
Andrechek, E.R.1
-
11
-
-
84925582075
-
The E2F transcription factors regulate tumor development and metastasis in a mouse model of metastatic breast cancer
-
Hollern DP, Honeysett J, Cardiff RD, Andrechek ER. The E2F transcription factors regulate tumor development and metastasis in a mouse model of metastatic breast cancer. Mol Cell Biol 2014; 34: 3229-3243.
-
(2014)
Mol Cell Biol
, vol.34
, pp. 3229-3243
-
-
Hollern, D.P.1
Honeysett, J.2
Cardiff, R.D.3
Andrechek, E.R.4
-
12
-
-
79952221879
-
Prediction and genetic demonstration of a role for activator E2Fs in Myc-induced tumors
-
Fujiwara K, Yuwanita I, Hollern DP, Andrechek ER. Prediction and genetic demonstration of a role for activator E2Fs in Myc-induced tumors. Cancer Res 2011; 71: 1924-1932.
-
(2011)
Cancer Res
, vol.71
, pp. 1924-1932
-
-
Fujiwara, K.1
Yuwanita, I.2
Hollern, D.P.3
Andrechek, E.R.4
-
13
-
-
70349496099
-
Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential
-
Andrechek ER, Cardiff RD, Chang JT, Gatza ML, Acharya CR, Potti A et al. Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential. Proc Natl Acad Sci USA 2009; 106: 16387-16392.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 16387-16392
-
-
Andrechek, E.R.1
Cardiff, R.D.2
Chang, J.T.3
Gatza, M.L.4
Acharya, C.R.5
Potti, A.6
-
14
-
-
84943613527
-
Comprehensive molecular portraits of invasive lobular breast cancer
-
Ciriello G, Gatza ML, Beck AH, Wilkerson MD, Rhie SK, Pastore A et al. Comprehensive molecular portraits of invasive lobular breast cancer. Cell 2015; 163: 506-519.
-
(2015)
Cell
, vol.163
, pp. 506-519
-
-
Ciriello, G.1
Gatza, M.L.2
Beck, A.H.3
Wilkerson, M.D.4
Rhie, S.K.5
Pastore, A.6
-
15
-
-
84922020381
-
An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer
-
Gatza ML, Silva GO, Parker JS, Fan C, Perou CM. An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer. Nat Genet 2014; 46: 1051-1059.
-
(2014)
Nat Genet
, vol.46
, pp. 1051-1059
-
-
Gatza, M.L.1
Silva, G.O.2
Parker, J.S.3
Fan, C.4
Perou, C.M.5
-
16
-
-
63649150787
-
A genomic strategy to elucidate modules of oncogenic pathway signaling networks
-
Chang JT, Carvalho C, Mori S, Bild AH, Gatza ML, Wang Q et al. A genomic strategy to elucidate modules of oncogenic pathway signaling networks. Mol Cell 2009; 34: 104-114.
-
(2009)
Mol Cell
, vol.34
, pp. 104-114
-
-
Chang, J.T.1
Carvalho, C.2
Mori, S.3
Bild, A.H.4
Gatza, M.L.5
Wang, Q.6
-
17
-
-
79960015997
-
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
-
Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, Shyr Y et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest 2011; 121: 2750-2767.
-
(2011)
J Clin Invest
, vol.121
, pp. 2750-2767
-
-
Lehmann, B.D.1
Bauer, J.A.2
Chen, X.3
Sanders, M.E.4
Chakravarthy, A.B.5
Shyr, Y.6
-
18
-
-
79952253747
-
Incidence and outcome of BRCA mutations in unselected patients with triple receptornegative breast cancer
-
Gonzalez-Angulo AM, Timms KM, Liu S, Chen H, Litton JK, Potter J et al. Incidence and outcome of BRCA mutations in unselected patients with triple receptornegative breast cancer. Clin Cancer Res 2011; 17: 1082-1089.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1082-1089
-
-
Gonzalez-Angulo, A.M.1
Timms, K.M.2
Liu, S.3
Chen, H.4
Litton, J.K.5
Potter, J.6
-
19
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 2005; 434: 917-921.
-
(2005)
Nature
, vol.434
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
Tutt, A.N.4
Johnson, D.A.5
Richardson, T.B.6
-
20
-
-
77955019276
-
Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: A proof-of-concept trial
-
Tutt A, Robson M, Garber JE, Domchek SM, Audeh MW, Weitzel JN et al. Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. Lancet 2010; 376: 235-244.
-
(2010)
Lancet
, vol.376
, pp. 235-244
-
-
Tutt, A.1
Robson, M.2
Garber, J.E.3
Domchek, S.M.4
Audeh, M.W.5
Weitzel, J.N.6
-
21
-
-
78751610848
-
Iniparib plus chemotherapy in metastatic triple-negative breast cancer
-
O'Shaughnessy J, Osborne C, Pippen JE, Yoffe M, Patt D, Rocha C et al. Iniparib plus chemotherapy in metastatic triple-negative breast cancer. N Engl J Med 2011; 364: 205-214.
-
(2011)
N Engl J Med
, vol.364
, pp. 205-214
-
-
O'Shaughnessy, J.1
Osborne, C.2
Pippen, J.E.3
Yoffe, M.4
Patt, D.5
Rocha, C.6
-
22
-
-
84883050174
-
Adjuvant bevacizumab-containing therapy in triple-negative breast cancer (BEATRICE): Primary results of a randomised, phase 3 trial
-
Cameron D, Brown J, Dent R, Jackisch C, Mackey J, Pivot X et al. Adjuvant bevacizumab-containing therapy in triple-negative breast cancer (BEATRICE): primary results of a randomised, phase 3 trial. Lancet Oncol 2013; 14: 933-942.
-
(2013)
Lancet Oncol
, vol.14
, pp. 933-942
-
-
Cameron, D.1
Brown, J.2
Dent, R.3
Jackisch, C.4
Mackey, J.5
Pivot, X.6
-
23
-
-
84940606731
-
Neoadjuvant plus adjuvant bevacizumab in early breast cancer (NSABP B-40 [NRG Oncology]): Secondary outcomes of a phase 3, randomised controlled trial
-
Bear HD, Tang G, Rastogi P, Geyer Jr CE, Liu Q, Robidoux A et al. Neoadjuvant plus adjuvant bevacizumab in early breast cancer (NSABP B-40 [NRG Oncology]): secondary outcomes of a phase 3, randomised controlled trial. Lancet Oncol 2015; 16: 1037-1048.
-
(2015)
Lancet Oncol
, vol.16
, pp. 1037-1048
-
-
Bear, H.D.1
Tang, G.2
Rastogi, P.3
Geyer, C.E.4
Liu, Q.5
Robidoux, A.6
-
24
-
-
84962284720
-
Bevacizumab plus neoadjuvant chemotherapy in patients with HER2-negative inflammatory breast cancer (BEVERLY-1): A multicentre, single-arm, phase 2 study
-
Bertucci F, Fekih M, Autret A, Petit T, Dalenc F, Levy C et al. Bevacizumab plus neoadjuvant chemotherapy in patients with HER2-negative inflammatory breast cancer (BEVERLY-1): a multicentre, single-arm, phase 2 study. Lancet Oncol 2016; 17: 600-611.
-
(2016)
Lancet Oncol
, vol.17
, pp. 600-611
-
-
Bertucci, F.1
Fekih, M.2
Autret, A.3
Petit, T.4
Dalenc, F.5
Levy, C.6
-
25
-
-
28244432561
-
Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells
-
Nahta R, Yuan LX, Zhang B, Kobayashi R, Esteva FJ. Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells. Cancer Res 2005; 65: 11118-11128.
-
(2005)
Cancer Res
, vol.65
, pp. 11118-11128
-
-
Nahta, R.1
Yuan, L.X.2
Zhang, B.3
Kobayashi, R.4
Esteva, F.J.5
-
26
-
-
33847013396
-
Lapatinib antitumor activity is not dependent upon phosphatase and tensin homologue deleted on chromosome 10 in ErbB2-overexpressing breast cancers
-
Xia W, Husain I, Liu L, Bacus S, Saini S, Spohn J et al. Lapatinib antitumor activity is not dependent upon phosphatase and tensin homologue deleted on chromosome 10 in ErbB2-overexpressing breast cancers. Cancer Res 2007; 67: 1170-1175.
-
(2007)
Cancer Res
, vol.67
, pp. 1170-1175
-
-
Xia, W.1
Husain, I.2
Liu, L.3
Bacus, S.4
Saini, S.5
Spohn, J.6
-
27
-
-
35148885729
-
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer
-
Berns K, Horlings HM, Hennessy BT, Madiredjo M, Hijmans EM, Beelen K et al. A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer. Cancer Cell 2007; 12: 395-402.
-
(2007)
Cancer Cell
, vol.12
, pp. 395-402
-
-
Berns, K.1
Horlings, H.M.2
Hennessy, B.T.3
Madiredjo, M.4
Hijmans, E.M.5
Beelen, K.6
-
28
-
-
40449113978
-
Met receptor contributes to trastuzumab resistance of Her2-overexpressing breast cancer cells
-
Shattuck DL, Miller JK, Carraway KL III, Sweeney C. Met receptor contributes to trastuzumab resistance of Her2-overexpressing breast cancer cells. Cancer Res 2008; 68: 1471-1477.
-
(2008)
Cancer Res
, vol.68
, pp. 1471-1477
-
-
Shattuck, D.L.1
Miller, J.K.2
Carraway, K.L.3
Sweeney, C.4
-
29
-
-
34247154498
-
A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo
-
Iwamaru A, Szymanski S, Iwado E, Aoki H, Yokoyama T, Fokt I et al. A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo. Oncogene 2007; 26: 2435-2444.
-
(2007)
Oncogene
, vol.26
, pp. 2435-2444
-
-
Iwamaru, A.1
Szymanski, S.2
Iwado, E.3
Aoki, H.4
Yokoyama, T.5
Fokt, I.6
-
30
-
-
77953932867
-
Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/ mTOR-addicted lymphomas
-
Bhatt AP, Bhende PM, Sin SH, Roy D, Dittmer DP, Damania B. Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/ mTOR-addicted lymphomas. Blood 2010; 115: 4455-4463.
-
(2010)
Blood
, vol.115
, pp. 4455-4463
-
-
Bhatt, A.P.1
Bhende, P.M.2
Sin, S.H.3
Roy, D.4
Dittmer, D.P.5
Damania, B.6
-
31
-
-
77956369534
-
Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase
-
Yang D, Liu H, Goga A, Kim S, Yuneva M, Bishop JM. Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase. Proc Natl Acad Sci USA 2010; 107: 13836-13841.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 13836-13841
-
-
Yang, D.1
Liu, H.2
Goga, A.3
Kim, S.4
Yuneva, M.5
Bishop, J.M.6
-
32
-
-
49149118719
-
BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models
-
Li D, Ambrogio L, Shimamura T, Kubo S, Takahashi M, Chirieac LR et al. BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models. Oncogene 2008; 27: 4702-4711.
-
(2008)
Oncogene
, vol.27
, pp. 4702-4711
-
-
Li, D.1
Ambrogio, L.2
Shimamura, T.3
Kubo, S.4
Takahashi, M.5
Chirieac, L.R.6
-
33
-
-
79956018943
-
Antitumor activities of JTP-74057 (GSK1120212), a novel MEK1/2 inhibitor, on colorectal cancer cell lines in vitro and in vivo
-
Yamaguchi T, Kakefuda R, Tajima N, Sowa Y, Sakai T. Antitumor activities of JTP-74057 (GSK1120212), a novel MEK1/2 inhibitor, on colorectal cancer cell lines in vitro and in vivo. Int J Oncol 2011; 39: 23-31.
-
(2011)
Int J Oncol
, vol.39
, pp. 23-31
-
-
Yamaguchi, T.1
Kakefuda, R.2
Tajima, N.3
Sowa, Y.4
Sakai, T.5
-
34
-
-
1342265719
-
SB-505124 is a selective inhibitor of transforming growth factor-beta type i receptors ALK4, ALK5, and ALK7
-
DaCosta Byfield S, Major C, Laping NJ, Roberts AB. SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptors ALK4, ALK5, and ALK7. Mol Pharmacol 2004; 65: 744-752.
-
(2004)
Mol Pharmacol
, vol.65
, pp. 744-752
-
-
DaCosta Byfield, S.1
Major, C.2
Laping, N.J.3
Roberts, A.B.4
-
35
-
-
67650506105
-
TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation
-
Tang Y, Wu X, Lei W, Pang L, Wan C, Shi Z et al. TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation. Nat Med 2009; 15: 757-765.
-
(2009)
Nat Med
, vol.15
, pp. 757-765
-
-
Tang, Y.1
Wu, X.2
Lei, W.3
Pang, L.4
Wan, C.5
Shi, Z.6
-
36
-
-
5144226211
-
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
-
Nagata Y, Lan KH, Zhou X, Tan M, Esteva FJ, Sahin AA et al. PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 2004; 6: 117-127.
-
(2004)
Cancer Cell
, vol.6
, pp. 117-127
-
-
Nagata, Y.1
Lan, K.H.2
Zhou, X.3
Tan, M.4
Esteva, F.J.5
Sahin, A.A.6
-
37
-
-
65549090180
-
Trastuzumabinduced HER reprogramming in 'resistant' breast carcinoma cells
-
Narayan M, Wilken JA, Harris LN, Baron AT, Kimbler KD, Maihle NJ. Trastuzumabinduced HER reprogramming in 'resistant' breast carcinoma cells. Cancer Res 2009; 69: 2191-2194.
-
(2009)
Cancer Res
, vol.69
, pp. 2191-2194
-
-
Narayan, M.1
Wilken, J.A.2
Harris, L.N.3
Baron, A.T.4
Kimbler, K.D.5
Maihle, N.J.6
-
38
-
-
65349101151
-
Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941
-
Junttila TT, Akita RW, Parsons K, Fields C, Lewis Phillips GD, Friedman LS et al. Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941. Cancer Cell 2009; 15: 429-440.
-
(2009)
Cancer Cell
, vol.15
, pp. 429-440
-
-
Junttila, T.T.1
Akita, R.W.2
Parsons, K.3
Fields, C.4
Lewis Phillips, G.D.5
Friedman, L.S.6
-
39
-
-
80051751593
-
Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2- overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy
-
Morrow PK, Wulf GM, Ensor J, Booser DJ, Moore JA, Flores PR et al. Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2- overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy. J Clin Oncol 2011; 29: 3126-3132.
-
(2011)
J Clin Oncol
, vol.29
, pp. 3126-3132
-
-
Morrow, P.K.1
Wulf, G.M.2
Ensor, J.3
Booser, D.J.4
Moore, J.A.5
Flores, P.R.6
-
40
-
-
84922369296
-
The cyclindependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2- negative, advanced breast cancer (PALOMA-1/TRIO-18): A randomised phase 2 study
-
Finn RS, Crown JP, Lang I, Boer K, Bondarenko IM, Kulyk SO et al. The cyclindependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2- negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study. Lancet Oncol 2015; 16: 25-35.
-
(2015)
Lancet Oncol
, vol.16
, pp. 25-35
-
-
Finn, R.S.1
Crown, J.P.2
Lang, I.3
Boer, K.4
Bondarenko, I.M.5
Kulyk, S.O.6
-
41
-
-
84915748814
-
Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth
-
Barbie TU, Alexe G, Aref AR, Li S, Zhu Z, Zhang X et al. Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth. J Clin Invest 2014; 124: 5411-5423.
-
(2014)
J Clin Invest
, vol.124
, pp. 5411-5423
-
-
Barbie, T.U.1
Alexe, G.2
Aref, A.R.3
Li, S.4
Zhu, Z.5
Zhang, X.6
-
42
-
-
84901982281
-
A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer
-
Hollern DP, Andrechek E. A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer. Breast Cancer Res 2014; 16: R59.
-
(2014)
Breast Cancer Res
, vol.16
, pp. R59
-
-
Hollern, D.P.1
Andrechek, E.2
-
43
-
-
84974633297
-
Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity
-
Hoefflin R, Lahrmann B, Warsow G, Hubschmann D, Spath C, Walter B et al. Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity. Nat Commun 2016; 7:11845.
-
(2016)
Nat Commun
, vol.7
, pp. 11845
-
-
Hoefflin, R.1
Lahrmann, B.2
Warsow, G.3
Hubschmann, D.4
Spath, C.5
Walter, B.6
-
44
-
-
84936890500
-
Subclonal diversification of primary breast cancer revealed by multiregion sequencing
-
Yates LR, Gerstung M, Knappskog S, Desmedt C, Gundem G, Van Loo P et al. Subclonal diversification of primary breast cancer revealed by multiregion sequencing. Nat Med 2015; 21: 751-759.
-
(2015)
Nat Med
, vol.21
, pp. 751-759
-
-
Yates, L.R.1
Gerstung, M.2
Knappskog, S.3
Desmedt, C.4
Gundem, G.5
Van Loo, P.6
-
45
-
-
73949083834
-
MEK1 mutations confer resistance to MEK and B-RAF inhibition
-
Emery CM, Vijayendran KG, Zipser MC, Sawyer AM, Niu L, Kim JJ et al. MEK1 mutations confer resistance to MEK and B-RAF inhibition. Proc Natl Acad Sci USA 2009; 106: 20411-20416.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 20411-20416
-
-
Emery, C.M.1
Vijayendran, K.G.2
Zipser, M.C.3
Sawyer, A.M.4
Niu, L.5
Kim, J.J.6
-
46
-
-
51349164790
-
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer
-
Carracedo A, Ma L, Teruya-Feldstein J, Rojo F, Salmena L, Alimonti A et al. Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer. J Clin Invest 2008; 118: 3065-3074.
-
(2008)
J Clin Invest
, vol.118
, pp. 3065-3074
-
-
Carracedo, A.1
Ma, L.2
Teruya-Feldstein, J.3
Rojo, F.4
Salmena, L.5
Alimonti, A.6
-
47
-
-
0033607633
-
Phosphorylation and regulation of Raf by Akt (protein kinase B)
-
Zimmermann S, Moelling K. Phosphorylation and regulation of Raf by Akt (protein kinase B). Science 1999; 286: 1741-1744.
-
(1999)
Science
, vol.286
, pp. 1741-1744
-
-
Zimmermann, S.1
Moelling, K.2
-
48
-
-
84863596086
-
MEK inhibition leads to PI3K/AKT activation by relieving a negative feedback on ERBB receptors
-
Turke AB, Song Y, Costa C, Cook R, Arteaga CL, Asara JM et al. MEK inhibition leads to PI3K/AKT activation by relieving a negative feedback on ERBB receptors. Cancer Res 2012; 72: 3228-3237.
-
(2012)
Cancer Res
, vol.72
, pp. 3228-3237
-
-
Turke, A.B.1
Song, Y.2
Costa, C.3
Cook, R.4
Arteaga, C.L.5
Asara, J.M.6
-
49
-
-
38049150665
-
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
-
Bean J, Brennan C, Shih JY, Riely G, Viale A, Wang L et al. MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proc Natl Acad Sci USA 2007; 104: 20932-20937.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20932-20937
-
-
Bean, J.1
Brennan, C.2
Shih, J.Y.3
Riely, G.4
Viale, A.5
Wang, L.6
-
50
-
-
32944481596
-
Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinib
-
Riely GJ, Pao W, Pham D, Li AR, Rizvi N, Venkatraman ES et al. Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treated with gefitinib or erlotinib. Clin Cancer Res 2006; 12(Pt 1): 839-844.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 839-844
-
-
Riely, G.J.1
Pao, W.2
Pham, D.3
Li, A.R.4
Rizvi, N.5
Venkatraman, E.S.6
-
51
-
-
84874778318
-
A mouse model with T58A mutations in Myc reduces the dependence on KRas mutations and has similarities to claudinlow human breast cancer
-
Hollern DP, Yuwanita I, Andrechek ER. A mouse model with T58A mutations in Myc reduces the dependence on KRas mutations and has similarities to claudinlow human breast cancer. Oncogene 2012; 32: 1296-1304.
-
(2012)
Oncogene
, vol.32
, pp. 1296-1304
-
-
Hollern, D.P.1
Yuwanita, I.2
Andrechek, E.R.3
-
52
-
-
0035942271
-
Significance analysis of microarrays applied to the ionizing radiation response
-
Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 2001; 98: 5116-5121.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5116-5121
-
-
Tusher, V.G.1
Tibshirani, R.2
Chu, G.3
-
53
-
-
62549125109
-
High-dimensional sparse factor modeling: Applications in gene expression genomics
-
Carvalho CM, Chang J, Lucas JE, Nevins JR, Wang Q, West M. High-dimensional sparse factor modeling: applications in gene expression genomics. J Am Stat Assoc 2008; 103: 1438-1456.
-
(2008)
J Am Stat Assoc
, vol.103
, pp. 1438-1456
-
-
Carvalho, C.M.1
Chang, J.2
Lucas, J.E.3
Nevins, J.R.4
Wang, Q.5
West, M.6
-
55
-
-
9444225935
-
Java Treeview-extensible visualization of microarray data
-
Alok JS, Moelling K. Java Treeview-extensible visualization of microarray data. Bioinformatics 2004; 20: 3246-3248.
-
(2004)
Bioinformatics
, vol.20
, pp. 3246-3248
-
-
Alok, J.S.1
Moelling, K.2
-
56
-
-
84881415504
-
A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models
-
Zhang X, Claerhout S, Prat A, Dobrolecki LE, Petrovic I, Lai Q et al. A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models. Cancer Res 2013; 73: 4885-4897.
-
(2013)
Cancer Res
, vol.73
, pp. 4885-4897
-
-
Zhang, X.1
Claerhout, S.2
Prat, A.3
Dobrolecki, L.E.4
Petrovic, I.5
Lai, Q.6
|