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Volumn 106, Issue 38, 2009, Pages 16387-16392

Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential

Author keywords

Breast; Cancer; Genomics; Mouse

Indexed keywords

BETA CATENIN; MYC PROTEIN; RAS PROTEIN; STAT3 PROTEIN;

EID: 70349496099     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0901250106     Document Type: Article
Times cited : (66)

References (27)
  • 1
    • 36248980204 scopus 로고    scopus 로고
    • Characterizing the cancer genome in lung adenocarcinoma
    • Weir BA, et al. (2007) Characterizing the cancer genome in lung adenocarcinoma. Nature 450:893-898.
    • (2007) Nature , vol.450 , pp. 893-898
    • Weir, B.A.1
  • 4
    • 34147224008 scopus 로고    scopus 로고
    • Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
    • Mullighan CG, et al. (2007) Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature 446:758-764.
    • (2007) Nature , vol.446 , pp. 758-764
    • Mullighan, C.G.1
  • 5
    • 54549094903 scopus 로고    scopus 로고
    • Somatic mutations effect key pathways in lung adenocarcinoma
    • Ding L, et al. (2008) Somatic mutations effect key pathways in lung adenocarcinoma. Nature 455:1069-1075.
    • (2008) Nature , vol.455 , pp. 1069-1075
    • Ding, L.1
  • 6
    • 0034696279 scopus 로고    scopus 로고
    • The mammary pathology of genetically engineered mice: The consensus report and recommendations from the Annapolis meeting
    • Cardiff RD, et al. (2000) The mammary pathology of genetically engineered mice: The consensus report and recommendations from the Annapolis meeting. Oncogene 19:968-988.
    • (2000) Oncogene , vol.19 , pp. 968-988
    • Cardiff, R.D.1
  • 7
    • 0037023755 scopus 로고    scopus 로고
    • Signaling networks that link cell proliferation and cell fate
    • Sears RC, Nevins JR (2002) Signaling networks that link cell proliferation and cell fate. J Biol Chem 277:11617-11620.
    • (2002) J Biol Chem , vol.277 , pp. 11617-11620
    • Sears, R.C.1    Nevins, J.R.2
  • 9
    • 0033082892 scopus 로고    scopus 로고
    • Ras enhances Myc protein stability
    • DOI 10.1016/S1097-2765(00)80308-1
    • Sears R, Leone G, DeGregori J, Nevins JR (1999) Ras enhances Myc protein stability. Mol Cell 3:169-179. (Pubitemid 29292618)
    • (1999) Molecular Cell , vol.3 , Issue.2 , pp. 169-179
    • Sears, R.1    Leone, G.2    Degregori, J.3    Nevins, J.R.4
  • 10
    • 0023631608 scopus 로고
    • Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo
    • DOI 10.1016/0092-8674(87)90449-1
    • Sinn E, et al. (1987) Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo. Cell 49:465-475. (Pubitemid 18091823)
    • (1987) Cell , vol.49 , Issue.4 , pp. 465-475
    • Sinn, E.1    Muller, W.2    Pattengale, P.3    Tepler, I.4    Wallace, R.5    Leder, P.6
  • 11
    • 0035126052 scopus 로고    scopus 로고
    • c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations
    • D'Crus CM, et al. (2001) c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations. Nat Med 7:235-239.
    • (2001) Nat Med , vol.7 , pp. 235-239
    • D'Crus, C.M.1
  • 14
    • 34548863946 scopus 로고    scopus 로고
    • Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
    • Herschkowitz JI, et al. (2007) Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol 8:R76.
    • (2007) Genome Biol , vol.8
    • Herschkowitz, J.I.1
  • 15
    • 0029041534 scopus 로고
    • Synergistic interaction of transforming growth factor alpha and c-myc in mouse mammary and salivary gland tumorigenesis
    • Amundadottir KT, Johnson MD, Merlino G, Smith GH, Dickson RB (1995) Synergistic interaction of transforming growth factor alpha and c-myc in mouse mammary and salivary gland tumorigenesis. Cell Growth Differ 6:737-748.
    • (1995) Cell Growth Differ , vol.6 , pp. 737-748
    • Amundadottir, K.T.1    Johnson, M.D.2    Merlino, G.3    Smith, G.H.4    Dickson, R.B.5
  • 16
    • 0031056820 scopus 로고    scopus 로고
    • Differential regulation of cell cycle characteristics and apoptosis in MMTV-myc and MMTV-ras mouse mammary tumors
    • Hundley JE, et al. (1997) Differential regulation of cell cycle characteristics and apoptosis in MMTV-myc and MMTV-ras mouse mammary tumors. Cancer Res 57:600-603.
    • (1997) Cancer Res , vol.57 , pp. 600-603
    • Hundley, J.E.1
  • 17
    • 51649085736 scopus 로고    scopus 로고
    • Identification of VEGF-regulated genes associated with increased lung metastatic potential: Functional involvement of tenascin-C in tumor growth and lung metastasis
    • Calvo A, et al. (2008) Identification of VEGF-regulated genes associated with increased lung metastatic potential: functional involvement of tenascin-C in tumor growth and lung metastasis. Oncogene 27:5373-5384.
    • (2008) Oncogene , vol.27 , pp. 5373-5384
    • Calvo, A.1
  • 18
    • 41649092988 scopus 로고    scopus 로고
    • Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer
    • Acharya CR, et al. (2008) Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer. JAMA 299:1574-1587.
    • (2008) JAMA , vol.299 , pp. 1574-1587
    • Acharya, C.R.1
  • 19
    • 23144461051 scopus 로고    scopus 로고
    • Genes that mediate breast cancer metastasis to lung
    • Minn AJ, et al. (2005) Genes that mediate breast cancer metastasis to lung. Nature 436:518-524.
    • (2005) Nature , vol.436 , pp. 518-524
    • Minn, A.J.1
  • 21
    • 51449085561 scopus 로고    scopus 로고
    • Generation of breast cancer stem cells through epithelial-mesenchymal transition
    • Morel AP, et al. (2008) Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLOS ONE 3:e2888.
    • (2008) PLOS ONE , vol.3
    • Morel, A.P.1
  • 23
    • 33750379861 scopus 로고    scopus 로고
    • Isoform-specific ras activation and oncogene dependence during MYC- And Wnt-induced mammary tumorigenesis
    • Jang JW, Boxer RB, Chodosh LA (2006) Isoform-specific ras activation and oncogene dependence during MYC- and Wnt-induced mammary tumorigenesis. Mol Cell Biol 26:8109-8121.
    • (2006) Mol Cell Biol , vol.26 , pp. 8109-8121
    • Jang, J.W.1    Boxer, R.B.2    Chodosh, L.A.3
  • 24
    • 0026587657 scopus 로고
    • Induction of mammary tumors by expression of polyomarirus middle T oncogene: A transgenic mouse model for metastatic disease
    • Guy CT, Cardiff RD, Muller WJ (1992) Induction of mammary tumors by expression of polyomarirus middle T oncogene: A transgenic mouse model for metastatic disease. Mol Cell Biol 12:954-961.
    • (1992) Mol Cell Biol , vol.12 , pp. 954-961
    • Guy, C.T.1    Cardiff, R.D.2    Muller, W.J.3
  • 25
    • 0027986757 scopus 로고
    • Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors
    • Siegel PM, Dankort DL, Hardy WR, Muller WJ (1994) Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors. Mol Cell Biol 14:7068-7077.
    • (1994) Mol Cell Biol , vol.14 , pp. 7068-7077
    • Siegel, P.M.1    Dankort, D.L.2    Hardy, W.R.3    Muller, W.J.4
  • 26
    • 0033513541 scopus 로고    scopus 로고
    • Accelerated mammary tumor development in mutant polyomavirus middle T transgenic mice expressing elevated levels of either the Shc or Grb2 adapter protein
    • Rauh MJ, et al. (1999) Accelerated mammary tumor development in mutant polyomavirus middle T transgenic mice expressing elevated levels of either the Shc or Grb2 adapter protein. Mol Cell Biol 19:8169-8179.
    • (1999) Mol Cell Biol , vol.19 , pp. 8169-8179
    • Rauh, M.J.1
  • 27
    • 50249151374 scopus 로고    scopus 로고
    • Patterns of cell signaling pathway activation that characterize mammary development
    • Andrechek ER, Mori S, Rempel RE, Chang JT, Nevins JR (2008) Patterns of cell signaling pathway activation that characterize mammary development. Development 135:2403-2411.
    • (2008) Development , vol.135 , pp. 2403-2411
    • Andrechek, E.R.1    Mori, S.2    Rempel, R.E.3    Chang, J.T.4    Nevins, J.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.