Downregulation of Iduna is associated with AIF nuclear translocation in neonatal brain after hypoxia–ischemia

Neuroscience

Volumn 346, Issue , 2017, Pages 74-80

  Yang, Xiaoxia ^a   Cheng, Jianhua ^a   Gao, Yubo ^a   Ding, Juan ^a   Ni, Xinli ^a  

^a NINGXIA MEDICAL UNIVERSITY   (China)

Author keywords

apoptosis inducing factor; hypoxia ischemia; Iduna; neonatal rats

Indexed keywords

APOPTOSIS INDUCING FACTOR; IDUNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN; UNCLASSIFIED DRUG; PDCD8 PROTEIN, RAT; RNF146 PROTEIN, RAT; UBIQUITIN PROTEIN LIGASE; UBIQUITINATED PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY LIGATION; ARTICLE; BRAIN CORTEX; BRAIN DAMAGE; BRAIN MATURATION; BRAIN NERVE CELL; CELL DAMAGE; CELL DEATH; CELL NUCLEUS; COMMON CAROTID ARTERY; CONTROLLED STUDY; DISEASE SEVERITY; DNA STRAND BREAKAGE; DOWN REGULATION; HISTOPATHOLOGY; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LEARNING; MEMORY; MORRIS WATER MAZE TEST; NERVE CELL NECROSIS; NEWBORN; NONHUMAN; PERINATAL PERIOD; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT; STAINING; TRANSMISSION ELECTRON MICROSCOPY; TUNEL ASSAY; UBIQUITINATION; WESTERN BLOTTING; ANIMAL; CELL SURVIVAL; METABOLISM; PATHOLOGY; PSYCHOLOGY; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS INDUCING FACTOR; CELL SURVIVAL; CEREBRAL CORTEX; DOWN-REGULATION; HYPOXIA-ISCHEMIA, BRAIN; LEARNING; MEMORY; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATED PROTEINS;

EID: 85010892520     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2017.01.010     Document Type: Article

References (24)

1. Andrabi, S.A., Dawson, T.M., Dawson, V.L., Mitochondrial and nuclear cross talk in cell death: parthanatos. Ann N Y Acad Sci 1147 (2008), 233–241.
2. Andrabi, S.A., Kang, H.C., Haince, J.F., Lee, Y.I., Zhang, J., Chi, Z., West, A.B., Koehler, R.C., Poirier, G.G., Dawson, T.M., Dawson, V.L., Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death. Nat Med 17 (2011), 692–699.
3. Brekke, E., Morken, T.S., Sonnewald, U., Glucose metabolism and astrocyte-neuron interactions in the neonatal brain. Neurochem Int 82 (2015), 33–41.
4. Carloni, S., Carnevali, A., Cimino, M., Balduini, W., Extended role of necrotic cell death after hypoxia-ischemia-induced neurodegeneration in the neonatal rat. Neurobiol Dis 27 (2007), 354–361.
5. Choi, H.Y., Lim, J.E., Hong, J.H., Curcumin interrupts the interaction between the androgen receptor and Wnt/β-catenin signaling pathway in LNCaP prostate cancer cells. Prostate Cancer Prostatic Dis 13:4 (2010), 343–349.
6. David, K.K., Andrabi, S.A., Dawson, T.M., Dawson, V.L., Parthanatos, a messenger of death. Front Biosci (Landmark Ed) 14 (2009), 1116–1128.
7. Feng, F.Y., de Bono, J.S., Rubin, M.A., Knudsen, K.E., Chromatin to clinic: the molecular rationale for PARP1 inhibitor function. Mol Cell 58 (2015), 925–934.
8. Ferriero, D.M., Neonatal brain injury. N Engl J Med 351 (2004), 1985–1995.
9. Hagberg, H., Wilson, M.A., Matsushita, H., Zhu, C., Lange, M., Gustavsson, M., Poitras, M.F., Dawson, T.M., Dawson, V.L., Northington, F., Johnston, M.V., PARP-1 gene disruption in mice preferentially protects males from perinatal brain injury. J Neurochem 90 (2004), 1068–1075.
10. Kang, H.C., Lee, Y.I., Shin, J.H., Andrabi, S.A., Chi, Z., Gagné, J.P., Lee, Y., Ko, H.S., Lee, B.D., Poirier, G.G., Dawson, V.L., Dawson, T.M., Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage. Proc Natl Acad Sci USA 108 (2011), 14103–14108.
11. Lafemina, M.J., Sheldon, R.A., Ferriero, D.M., Acute hypoxia–ischemia results in hydrogen peroxide accumulation in neonatal but not adult mouse brain. Pediatr Res 59 (2006), 680–683.
12. Leviton, A., Gressens, P., Neuronal damage accompanies perinatal white-matter damage. Trends Neurosci 30 (2007), 473–478.
13. Lu, P., Kamboj, A., Gibson, S.B., Anderson, C.M., Poly(ADP-ribose) polymerase-1 causes mitochondrial damage and neuron death mediated by Bnip3. J Neurosci 34 (2014), 15975–15987.
14. Northington, F.J., Chavez-Valdez, R., Martin, L.J., Neuronal cell death in neonatal hypoxia–ischemia. Ann Neurol 69 (2011), 743–758.
15. Rice, J.E. 3rd, Vannucci, R.C., Brierley, J.B., The influence of immaturity on hypoxic–ischemic brain damage in the rat. Ann Neurol 9 (1981), 131–141.
16. Sheldon, R.A., Jiang, X., Francisco, C., Christen, S., Vexler, Z.S., Täuber, M.G., Ferriero, D.M., Manipulation of antioxidant pathways in neonatal murine brain. Pediatr Res 56 (2004), 656–662.
17. van Velthoven, C.T., Kavelaars, A., Heijnen, C.J., Mesenchymal stem cells as a treatment for neonatal ischemic brain damage. Pediatr Res 71 (2012), 474–481.
18. Wang, L.B., Zhang, L.Y., Shan, C.H., A new form of cell death: parthanatos. Yi Chuan 32 (2010), 881–885.
19. Wang, X., Carlsson, Y., Basso, E., Zhu, C., Rousset, C.I., Rasola, A., Johansson, B.R., Blomgren, K., Mallard, C., Bernardi, P., Forte, M.A., Hagberg, H., Developmental shift of cyclophilin D contribution to hypoxic–ischemic brain injury. J Neurosci 29 (2009), 2588–2596.
20. Wang, Y., Dawson, V.L., Dawson, T.M., Poly(ADP-ribose) signals to mitochondrial AIF: a key event in parthanatos. Exp Neurol 218 (2009), 193–202.
21. Wang, Y., Kim, N.S., Haince, J.F., Kang, H.C., David, K.K., Andrabi, S.A., Poirier, G.G., Dawson, V.L., Dawson, T.M., Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos). Sci Signal, 4, 2011, ra20.
22. Zhou, Z.D., Chan, C.H., Xiao, Z.C., Tan, E.K., Ring finger protein 146/Iduna is a poly(ADP-ribose) polymer binding and PARsylation dependent E3 ubiquitin ligase. Cell Adh Migr 5 (2011), 463–471.
23. Zhu, C., Wang, X., Huang, Z., Qiu, L., Xu, F., Vahsen, N., Nilsson, M., Eriksson, P.S., Hagberg, H., Culmsee, C., Plesnila, N., Kroemer, G., Blomgren, K., Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia–ischemia. Cell Death Differ 14 (2007), 775–784.
24. Zhu, C., Wang, X., Xu, F., Bahr, B.A., Shibata, M., Uchiyama, Y., Hagberg, H., Blomgren, K., The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia–ischemia. Cell Death Differ 12 (2005), 162–176.