Cell cycle regulated transcription: From yeast to cancer.

F1000Research

Volumn 5, Issue , 2016, Pages

  McInerny, Christopher J ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FORKHEAD TRANSCRIPTION FACTOR; MBF PROTEIN; NRM1 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F; UNCLASSIFIED DRUG;

CARCINOGENESIS; CELL CYCLE; CELL DIVISION; CELL PROLIFERATION; GENE EXPRESSION; GENETIC REGULATION; GENETIC TRANSCRIPTION; HUMAN; MALIGNANT NEOPLASM; NONHUMAN; REVIEW; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; TRANSCRIPTION REGULATION; YEAST;

EID: 85010845199     PISSN: None     EISSN: 20461402     Source Type: Journal    
DOI: 10.12688/F1000RESEARCH.8111.1     Document Type: Review

References (26)

1. Haase SB, Wittenberg C: Topology and control of the cell-cycle-regulated transcriptional circuitry. Genetics. 2014; 196(1): 65-90.
2. Bähler J: Cell-cycle control of gene expression in budding and fission yeast. Annu Rev Genet. 2005; 39: 69-94.
3. McInerny CJ: Cell cycle regulated gene expression in yeasts. Adv Genet. 2011; 73: 51-85.
4. Boros J, Lim FL, Darieva Z, et al.: Molecular determinants of the cell-cycle regulated Mcm1p-Fkh2p transcription factor complex. Nucleic Acids Res. 2003; 31(9): 2279-88.
5. Darieva Z, Clancy A, Bulmer R, et al.: A competitive transcription factor binding mechanism determines the timing of late cell cycle-dependent gene expression. Mol Cell. 2010; 38(1): 29-40.
6. Papadopoulou K, Ng SS, Ohkura H, et al.: Regulation of gene expression during M-G1-phase in fission yeast through Plo1p and forkhead transcription factors. J Cell Sci. 2008; 121(Pt 1): 38-47.
7. Suárez MB, Alonso-Nuñez ML, del Rey F, et al.: Regulation of Ace2-dependent genes requires components of the PBF complex in Schizosaccharomyces pombe. Cell Cycle. 2015; 14(19): 3124-37.
8. Murakami H, Aiba H, Nakanishi M, et al.: Regulation of yeast forkhead transcription factors and FoxM1 by cyclin-dependent and polo-like kinases. Cell Cycle. 2010; 9(16): 3233-42.
9. Grant GD, Brooks L 3rd, Zhang X, et al.: Identification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors. Mol Biol Cell. 2013; 24(23): 3634-50.
10. Dansen TB, Kalkhoven E: Targeting FOXO1 as an option to treat obesity? Cell Cycle. 2015; 14(16): 2558.
11. Martins R, Lithgow GJ, Link W: Long live FOXO: unraveling the role of FOXO proteins in aging and longevity. Aging Cell. 2016; 15(2): 196-207.
12. Coomans de Brachène A, Demoulin JB: FOXO transcription factors in cancer development and therapy. Cell Mol Life Sci. 2016; 73(6): 1159-72.
13. Zhang T, Kim DH, Xiao X, et al.: FoxO1 Plays an Important Role in Regulating β-Cell Compensation for Insulin Resistance in Male Mice. Endocrinology. 2016; 157(3): 1055-70.
14. Tosiek MJ, Fiette L, El Daker S, et al.: IL-15-dependent balance between Foxp3 and RORt expression impacts inflammatory bowel disease. Nat Commun. 2016; 7: 10888.
15. Wilhelm K, Happel K, Eelen G, et al.: FOXO1 couples metabolic activity and growth state in the vascular endothelium. Nature. 2016; 529(7585): 216-20.
16. Hill R, Kalathur RK, Callejas S, et al.: A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes. Breast Cancer Res. 2014; 16(6): 482.
17. Bullock M: FOXO factors and breast cancer: outfoxing endocrine resistance. Endocr Relat Cancer. 2016; 23(2): R113-30.
18. de Bruin RA, Kalashnikova TI, Chahwan C, et al.: Constraining G1-specific transcription to late G1 phase: the MBF-associated corepressor Nrm1 acts via negative feedback. Mol Cell. 2006; 23(4): 483-96.
19. Ostapenko D, Solomon MJ: Anaphase promoting complex-dependent degradation of transcriptional repressors Nrm1 and Yhp1 in Saccharomyces cerevisiae. Mol Biol Cell. 2011; 22(13): 2175-84.
20. Ofir A, Hofmann K, Weindling E, et al.: Role of a Candida albicans Nrm1/Whi5 homologue in cell cycle gene expression and DNA replication stress response. Mol Microbiol. 2012; 84(4): 778-94.
21. Travesa A, Kalashnikova TI, de Bruin RA, et al.: Repression of G1/S transcription is mediated via interaction of the GTB motifs of Nrm1 and Whi5 with Swi6. Mol Cell Biol. 2013; 33(8): 1476-86.
22. Polager S, Ginsberg D: E2F-at the crossroads of life and death. Trends Cell Biol. 2008; 18(11): 528-35.
23. Chen HZ, Tsai SY, Leone G: Emerging roles of E2Fs in cancer: an exit from cell cycle control. Nat Rev Cancer. 2009; 9(11): 785-97.
24. Engelmann D, Pützer BM: The dark side of E2F1: in transit beyond apoptosis. Cancer Res. 2012; 72(3): 571-5.
25. Park SA, Platt J, Lee JW, et al.: E2F8 as a novel therapeutic target for lung cancer. J Natl Cancer Inst. 2015; 107(9): pii: djv151.
26. Caetano C, Limbo O, Farmer S, et al.: Tolerance of deregulated G1/S transcription depends on critical G1/S regulon genes to prevent catastrophic genome instability. Cell Rep. 2014; 9(6): 2279-89.