Molecular determinants of the cell-cycle regulated Mcm1p-Fkh2p transcription factor complex

Nucleic Acids Research

Volumn 31, Issue 9, 2003, Pages 2279-2288

  Boros, Joanna ^a,b   Lim, Fei Ling ^a,d   Darieva, Zoulfia ^a   Pic Taylor, Aline ^c   Harman, Ruth ^a   Morgan, Brian A ^c   Sharrocks, Andrew D ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF WARSAW   (Poland)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MADS DOMAIN PROTEIN; SERUM RESPONSE FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FKH2P; TRANSCRIPTION FACTOR MCM1P; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; CLB2 PROTEIN, S CEREVISIAE; CYCLIN B; DNA BINDING PROTEIN; FKH2 PROTEIN, S CEREVISIAE; FORKHEAD TRANSCRIPTION FACTOR; FUNGAL PROTEIN; MINICHROMOSOME MAINTENANCE PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; SWI5 PROTEIN, FUNGUS;

ARTICLE; BINDING SITE; CELL CYCLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA BINDING; DNA DETERMINATION; DNA FLANKING REGION; DNA SYNTHESIS INHIBITION; GENE CLUSTER; GENE MAPPING; GENE MUTATION; GENETIC CONSERVATION; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SACCHAROMYCES CEREVISIAE; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUTATION; PHYSIOLOGY; PROMOTER REGION;

CERVUS ELAPHUS; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

BINDING SITES; CELL CYCLE; CELL CYCLE PROTEINS; CYCLIN B; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; FUNGAL PROTEINS; MCM1 PROTEIN; MUTATION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS;

EID: 0038750919     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg347     Document Type: Article

References (39)

1. Dolan,J.W. and Fields,S. (1991) Cell-type-specific transcription in yeast. Biochim. Biophys. Acta, 1088, 155-169.
2. Shore,P. and Sharrocks,A.D. (1995) The MADS-box family of transcription factors. Eur. J. Biochem., 229, 1-13.
3. McInerny,C.J., Partridge,J.F., Mikesell,G.E., Creemer,D.P. and Breeden,L.L. (1997) A novel Mcm1-dependent element in the SWI4, CLN3, CDC6, and CDC47 promoters activates M/G1-specific transcription. Genes Dev., 11, 1277-1288.
4. Althoefer,H., Schleiffer,A., Wassmann,K., Nordheim,A. and Ammerer,G. (1995) Mcm1 is required to coordinate G2-specific transcription in Saccharomyces cerevisiae. Mol. Cell. Biol., 15, 5917-5928.
5. Breeden,L.L. (2000) Cyclin transcription: timing is everything. Curr. Biol., 10, R586-588.
6. Koranda,M., Schleiffer,A., Endler,L. and Ammerer,G. (2000) Forkhead-like transcription factors recruit Ndd1 to the chromatin of G2/M-specific promoters. Nature, 406, 94-98.
7. Kumar,R., Reynolds,D.M., Shevchenko,A., Shevchenko,A., Goldstone,S.D. and Dalton,S. (2000) Forkhead transcription factors, Fkh1p and Fkh2p, collaborate with Mcm1p to control transcription required for M-phase. Curr. Biol., 10, 896-906.
8. Pic,A., Lim,F.-L., Ross,S.J., Johnson,A.L., Sultan,R.A., West,A.G., Johnston,L.H., Sharrocks,A.D. and Morgan,B.A. (2000) The forkhead protein Fkh2 is a component of the yeast cell cycle transcription factor SFF. EMBO J., 19, 3750-3761.
9. Zhu,G., Spellman,P.T., Volpe,T., Brown,P.O., Botstein,D., Davis,T.N. and Futcher,B. (2000) Two yeast forkhead genes regulate the cell cycle and pseudohyphal growth. Nature, 406, 90-94.
10. Hollenhorst,P.C., Pietz,G. and Fox,C.A. (2001) Mechanisms controlling differential promoter-occupancy by the yeast forkhead proteins Fkh1p and Fkh2p: implications for regulating the cell cycle and differentiation. Genes Dev., 15, 2445-2456.
11. Sharrocks,A.D. (2002) Complexities in ETS-domain transcription factor function and regulation; lessons from the TCF subfamily. Biochem. Soc. Trans, 30, 1-9.
12. Treisman,R. (1994) Ternary complex factors: growth regulated transcriptional activators. Curr. Opin. Genet. Dev., 4, 96-101
13. Mueller,C.G. and Nordheim,A. (1991) A protein domain conserved between yeast MCM1 and human SRF directs ternary complex formation. EMBO J., 10, 4219-4229.
14. Shaw,P.E. (1992) Ternary complex formation over the c-fos serum response element: p62TCF exhibits dual component specificity with contacts to DNA and an extended structure in the DNA-binding domain of p67SRF. EMBO J., 11, 3011-3019.
15. Wynne,J. and Treisman,R. (1992) SRF and MCM1 have related but distinct DNA binding specificities. Nucleic Acids Res., 20, 3297-3303
16. Hassler,M. and Richmond,T.J. (2001) The B-box dominates SAP-1-SRF interactions in the structure of the ternary complex. EMBO J., 20, 3018-3028.
17. Ling,Y., Lakey,J., Roberts,E.C. and Sharrocks,A.D. (1997) Molecular characterisation of the B-box protein-protein interaction motif of the ETS-domain transcription factors Elk-1. EMBO J., 16, 2431-2440.
18. Ling,Y., West,A.G., Roberts,E.C., Lakey,J.H. and Sharrocks,A.D. (1998) Interaction of transcription factors with SRF: identification of the Elk-1 binding surface. J. Biol. Chem., 273, 10506-10514.
19. Tan,S. and Richmond,T.J. (1998) Crystal structure of the yeast MATalpha2/MCM1/DNA ternary complex. Nature, 391, 660-666.
20. SRF and RSRFC4. Nucleic Acids Res., 21, 215-221.
21. West,A.G., Causier,B.E., Davies,B. and Sharrocks,A.D. (1998) DNA binding and dimerisation determinants of the Antirrhinum majus MADS-box transcription factors. Nucleic Acids Res., 26, 5277-5287.
22. West,A.G. and Sharrocks,A.D. (1999) MADS-box transcription factors adopt different mechanisms to bend DNA. J. Mol. Biol., 286, 1311-1323.
23. Shore,P. and Sharrocks,A.D. (1994) The transcription factors Elk-1 and serum response factor interact by direct protein-protein contacts mediated by a short region of Elk-1. Mol. Cell. Biol., 14, 3283-3291.
24. Guan,K. and Dixon,J.E. (1991) Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal. Biochem., 192, 262-267.
25. Bruhn,L. and Sprague,G.F.S.,Jr (1994) MCM1 point mutants deficient in expression of α-specific genes: residues important for interaction with α1. Mol. Cell. Biol., 14, 2534-2544.
26. West,A.G., Shore,P. and Sharrocks,A.D. (1997) DNA binding by MADS-box transcription factors: a molecular mechanism for differential DNA bending. Mol. Cell. Biol., 17, 2876-2887
27. Galanis,A., Yang,S.-H. and Sharrocks,A.D. (2001) Targeting of MAP kinase signal transduction pathways to SAP-1. J. Biol. Chem., 276, 965-973.
28. Sherman,F., Fink,G.R. and Hicks,J.B. (1986) Methods in Yeast Genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
29. Berben,G., Dumont,J., Gilliquet,V., Bolle,P.A. and Hilger,F. (1991) The YDp plasmids: a uniform set of vectors bearing versatile gene disruption cassettes for Saccharomyces cerevisiae. Yeast, 7, 475-477.
30. Schiestl,R.H. and Gietz,R.D. (1989) High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr. Genet., 16, 339-346.
31. Boeke,J.D., La Croute,F. and Fink,G.R. (1984) A positive screen for mutants lacking 5′-phosphate decarboxylase activity in yeast: 5′-fluoroorotic acid resistance. Mol. Gen. Genet., 197, 345-346.
32. Treisman,R., Marais,R. and Wynne,J. (1992) Spatial flexibility in complexes between SRF and its accessory proteins. EMBO J., 11, 4631-4640.
33. Lim,F.-L., Hayes,A., West,A.G., Pic-Taylor,A., Darieva,Z., Morgan,B.A., Oliver,S.G. and Sharrocks,A.D. (2003) Mcm1p-induced DNA bending regulates the formation of ternary transcription factor complexes. Mol. Cell. Biol., 23, 450-461.
34. Bruhn,L., Hwang-Shum,J.J. and Sprague,G.F.,Jr (1992) The N-terminal 96 residues of MCM1, a regulator of cell type-specific genes in Saccharomyces cerevisiae, are sufficient for DNA binding, transcription activation, and interaction with alpha 1. Mol. Cell. Biol., 12, 3563-3572.
35. Loy,C.J., Lydall,D. and Surana,U. (1999) NDD1, a high-dosage suppressor of cdc28-1N, is essential for expression of a subset of late-S-phase-specific genes in Saccharomyces cerevisiae. Mol. Cell. Biol., 19, 3312-3327.
36. Pellegrini,L., Tan,S. and Richmond,T.J. (1995) Structure of serum response factor core bound to DNA. Nature, 376, 490-498.
37. Simon,I., Barnett,J., Hannett,N., Harbison,C.T., Rinaldi,N.J., Volkert,T.L., Wyrick,J.J., Zeitlinger,J., Gifford,D.K., Jaakkola,T.S. and Young,R.A. (2001) Serial regulation of transcriptional regulators in the yeast cell cycle. Cell, 106, 697-708.
38. Smith,D.L., Desai,A.B. and Johnson,A.D. (1995) DNA-bending by the α1 and α2 homeodomain proteins from yeast. Nucleic Acids Res., 23, 1239-1243.
39. Graves,B.J., Cowley,D.O., Goetz,T.L., Petersen,J.M., Jonsen,M.D. and Gillespie,M.E. (1998) Autoinhibition as a transcriptional regulatory mechanism. Cold Spring Harb. Symp. Quant. Biol., 63, 621-629.