Temporally Distinct Six2-Positive Second Heart Field Progenitors Regulate Mammalian Heart Development and Disease

Cell Reports

Volumn 18, Issue 4, 2017, Pages 1019-1032

  Zhou, Zhengfang ^a,b   Wang, Jingying ^a   Guo, Chaoshe ^a   Chang, Weiting ^c   Zhuang, Jian ^b   Zhu, Ping ^b   Li, Xue ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

cardiac neural crest; cardiac outflow tract; common arterial trunk; diphtheria toxin fragment A; DTA; high resolution episcopic microscopy; HREM; intrapericardial arterial trunk; persistent truncus arteriosus; progenitor; PTA; second heart field; Shh; Six1; Six2; tetralogy of Fallot; TOF

Indexed keywords

PROTEIN SIX2; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; MESSENGER RNA; SELECTIVE ESTROGEN RECEPTOR MODULATOR; SHH PROTEIN, MOUSE; SIX2 PROTEIN, MOUSE; TAMOXIFEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC STEM CELL; CARDIOMYOPATHY; CONGENITAL HEART DISEASE; CONTROLLED STUDY; EMBRYO; FEMALE; GENE DELETION; GENE EXPRESSION; HEART DEVELOPMENT; HEART DISEASE; HEART RIGHT VENTRICLE; HEART RIGHT VENTRICLE HYPOPLASIA; HEART VENTRICLE HYPERTROPHY; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PULMONARY VALVE ATRESIA; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SIX2 GENE; ANIMAL; CARDIAC MUSCLE; CYTOLOGY; DIAGNOSTIC IMAGING; DRUG EFFECTS; ECHOCARDIOGRAPHY; FLUORESCENCE IN SITU HYBRIDIZATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEART; HEART VENTRICLE; HEART VENTRICLE FUNCTION; MAMMALIAN EMBRYO; METABOLISM; MUTAGENESIS; PATHOLOGY; PHYSIOLOGY; STEM CELL;

ANIMALS; ECHOCARDIOGRAPHY; EMBRYO, MAMMALIAN; HEART; HEART DISEASES; HEART VENTRICLES; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; IN SITU HYBRIDIZATION, FLUORESCENCE; MICE; MUTAGENESIS; MYOCARDIUM; RNA, MESSENGER; SELECTIVE ESTROGEN RECEPTOR MODULATORS; SIGNAL TRANSDUCTION; STEM CELLS; TAMOXIFEN; TRANSCRIPTION FACTORS; VENTRICULAR FUNCTION;

EID: 85010339297     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.01.002     Document Type: Article

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