메뉴 건너뛰기




Volumn 64, Issue , 2017, Pages 39-51

Nitrite increases glucose-stimulated insulin secretion and islet insulin content in obese type 2 diabetic male rats

Author keywords

Glucose tolerance; Inflammation; Insulin resistance; Insulin secretion; Nitrite; Type 2 diabetes

Indexed keywords

CHOLESTEROL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; GLUCOSE TRANSPORTER 4; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INTERLEUKIN 1BETA; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NITRIC OXIDE; SODIUM NITRITE; STREPTOZOCIN; TRIACYLGLYCEROL; NITRITE;

EID: 85010008102     PISSN: 10898603     EISSN: 10898611     Source Type: Journal    
DOI: 10.1016/j.niox.2017.01.003     Document Type: Article
Times cited : (70)

References (72)
  • 2
    • 33745851096 scopus 로고    scopus 로고
    • Insulin resistance and pancreatic β cell failure
    • [2] Kasuga, M., Insulin resistance and pancreatic β cell failure. J. Clin. Investigation, 116, 2006, 1756, 10.1172/JCI29189.
    • (2006) J. Clin. Investigation , vol.116 , pp. 1756
    • Kasuga, M.1
  • 3
    • 78049238308 scopus 로고    scopus 로고
    • Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice
    • [3] Carlström, M., Larsen, F.J., Nyström, T., Hezel, M., Borniquel, S., Weitzberg, E., Lundberg, J.O., Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice. Proc. Natl. Acad. Sci. 107 (2010), 17716–17720, 10.1073/pnas.1008872107.
    • (2010) Proc. Natl. Acad. Sci. , vol.107 , pp. 17716-17720
    • Carlström, M.1    Larsen, F.J.2    Nyström, T.3    Hezel, M.4    Borniquel, S.5    Weitzberg, E.6    Lundberg, J.O.7
  • 4
    • 34547903856 scopus 로고    scopus 로고
    • Diet-induced obesity and diabetes reduce coronary responses to nitric oxide due to reduced bioavailability in isolated mouse hearts
    • [4] Bender, S.B., Herrick, E.K., Lott, N.D., Klabunde, R.E., Diet-induced obesity and diabetes reduce coronary responses to nitric oxide due to reduced bioavailability in isolated mouse hearts. Diabetes Obes. Metab. 9 (2007), 688–696, 10.1111/j.1463-1326.2006.00650.x.
    • (2007) Diabetes Obes. Metab. , vol.9 , pp. 688-696
    • Bender, S.B.1    Herrick, E.K.2    Lott, N.D.3    Klabunde, R.E.4
  • 5
    • 84874936090 scopus 로고    scopus 로고
    • Effect of dietary nitrate on blood pressure, endothelial function, and insulin sensitivity in type 2 diabetes
    • [5] Gilchrist, M., Winyard, P.G., Aizawa, K., Anning, C., Shore, A., Benjamin, N., Effect of dietary nitrate on blood pressure, endothelial function, and insulin sensitivity in type 2 diabetes. Free Radic. Biol. Med. 60 (2013), 89–97, 10.1016/j.freeradbiomed.2013.01.024.
    • (2013) Free Radic. Biol. Med. , vol.60 , pp. 89-97
    • Gilchrist, M.1    Winyard, P.G.2    Aizawa, K.3    Anning, C.4    Shore, A.5    Benjamin, N.6
  • 7
    • 79551583060 scopus 로고    scopus 로고
    • Raised plasma insulin level and Homeostasis Model Assessment (HOMA) score in cerebral malaria: evidence for insulin resistance and marker of virulence
    • [7] Eltahir, E.M., ElGhazali, G., A-Elgadir, T.M.E., A-Elbasit, I.E., Elbashir, M.I., Giha, H.A., Raised plasma insulin level and Homeostasis Model Assessment (HOMA) score in cerebral malaria: evidence for insulin resistance and marker of virulence. Acta Biochim. Pol. 57 (2010), 513–520.
    • (2010) Acta Biochim. Pol. , vol.57 , pp. 513-520
    • Eltahir, E.M.1    ElGhazali, G.2    A-Elgadir, T.M.E.3    A-Elbasit, I.E.4    Elbashir, M.I.5    Giha, H.A.6
  • 8
    • 75049084324 scopus 로고    scopus 로고
    • Nitric oxide and clustering of metabolic syndrome components in pediatrics
    • [8] Ghasemi, A., Zahediasl, S., Azizi, F., Nitric oxide and clustering of metabolic syndrome components in pediatrics. Eur. J. Epidemiol. 25 (2010), 45–53, 10.1007/s10654-009-9382-3.
    • (2010) Eur. J. Epidemiol. , vol.25 , pp. 45-53
    • Ghasemi, A.1    Zahediasl, S.2    Azizi, F.3
  • 9
    • 84982839441 scopus 로고    scopus 로고
    • Dietary nitrate improves age-related hypertension and metabolic abnormalities in rats via modulation of angiotensin II receptor signaling and inhibition of superoxide generation
    • [9] Hezel, M., Peleli, M., Liu, M., Zollbrecht, C., Jensen, B.L., Checa, A., Giulietti, A., Wheelock, C.E., Lundberg, J.O., Weitzberg, E., Carlstrom, M., Dietary nitrate improves age-related hypertension and metabolic abnormalities in rats via modulation of angiotensin II receptor signaling and inhibition of superoxide generation. Free Radic. Biol. Med. 99 (2016), 87–99, 10.1016/j.freeradbiomed.2016.07.025.
    • (2016) Free Radic. Biol. Med. , vol.99 , pp. 87-99
    • Hezel, M.1    Peleli, M.2    Liu, M.3    Zollbrecht, C.4    Jensen, B.L.5    Checa, A.6    Giulietti, A.7    Wheelock, C.E.8    Lundberg, J.O.9    Weitzberg, E.10    Carlstrom, M.11
  • 10
    • 84876877355 scopus 로고    scopus 로고
    • Potential therapeutic effects of nitrate/nitrite and type 2 diabetes mellitus
    • [10] Ghasemi, A., Zahediasl, S., Potential therapeutic effects of nitrate/nitrite and type 2 diabetes mellitus. Int. J. Endocrinol. Metabolism 11 (2013), 63–64, 10.5812/ijem.9103.
    • (2013) Int. J. Endocrinol. Metabolism , vol.11 , pp. 63-64
    • Ghasemi, A.1    Zahediasl, S.2
  • 11
    • 84914165899 scopus 로고    scopus 로고
    • Dietary nitrite supplementation improves insulin resistance in type 2 diabetic KKA y mice
    • [11] Ohtake, K., Nakano, G., Ehara, N., Sonoda, K., Ito, J., Uchida, H., Kobayashi, J., Dietary nitrite supplementation improves insulin resistance in type 2 diabetic KKA y mice. Nitric Oxide 44 (2015), 31–38, 10.1016/j.niox.2014.11.009.
    • (2015) Nitric Oxide , vol.44 , pp. 31-38
    • Ohtake, K.1    Nakano, G.2    Ehara, N.3    Sonoda, K.4    Ito, J.5    Uchida, H.6    Kobayashi, J.7
  • 12
    • 84929301616 scopus 로고    scopus 로고
    • Beneficial effects of inorganic nitrate/nitrite in type 2 diabetes and its complications
    • [12] Bahadoran, Z., Ghasemi, A., Mirmiran, P., Azizi, F., Hadaegh, F., Beneficial effects of inorganic nitrate/nitrite in type 2 diabetes and its complications. Nutr. metabolism 12 (2015), 12–16, 10.1186/s12986-015-0013-6.
    • (2015) Nutr. metabolism , vol.12 , pp. 12-16
    • Bahadoran, Z.1    Ghasemi, A.2    Mirmiran, P.3    Azizi, F.4    Hadaegh, F.5
  • 13
    • 84914163771 scopus 로고    scopus 로고
    • Dietary nitrate improves glucose tolerance and lipid profile in an animal model of hyperglycemia
    • [13] Khalifi, S., Rahimipour, A., Jeddi, S., Ghanbari, M., Kazerouni, F., Ghasemi, A., Dietary nitrate improves glucose tolerance and lipid profile in an animal model of hyperglycemia. Nitric Oxide 44 (2015), 24–30, 10.1016/j.niox.2014.11.011.
    • (2015) Nitric Oxide , vol.44 , pp. 24-30
    • Khalifi, S.1    Rahimipour, A.2    Jeddi, S.3    Ghanbari, M.4    Kazerouni, F.5    Ghasemi, A.6
  • 14
    • 84940863892 scopus 로고    scopus 로고
    • In adenosine A2b knockouts acute treatment with inorganic nitrate improves glucose disposal, oxidative stress, and AMPK signaling in the liver
    • [14] Peleli, M., Hezel, M., Zollbrecht, C., Persson, A.E.G., Lundberg, J.O., Weitzberg, E., Fredholm, B.B., Carlström, M., In adenosine A2b knockouts acute treatment with inorganic nitrate improves glucose disposal, oxidative stress, and AMPK signaling in the liver. Front. Physiol., 6, 2015, 222, 10.3389/fphys.2015.00222.
    • (2015) Front. Physiol. , vol.6 , pp. 222
    • Peleli, M.1    Hezel, M.2    Zollbrecht, C.3    Persson, A.E.G.4    Lundberg, J.O.5    Weitzberg, E.6    Fredholm, B.B.7    Carlström, M.8
  • 16
    • 66149131355 scopus 로고    scopus 로고
    • Dietary nitrite prevents hypercholesterolemic microvascular inflammation and reverses endothelial dysfunction
    • [16] Stokes, K.Y., Dugas, T.R., Tang, Y., Garg, H., Guidry, E., Bryan, N.S., Dietary nitrite prevents hypercholesterolemic microvascular inflammation and reverses endothelial dysfunction. Am. J. Physiol. Heart Circ. Physiol. 296 (2009), H1281–H1288, 10.1152/ajpheart.01291.2008.
    • (2009) Am. J. Physiol. Heart Circ. Physiol. , vol.296 , pp. H1281-H1288
    • Stokes, K.Y.1    Dugas, T.R.2    Tang, Y.3    Garg, H.4    Guidry, E.5    Bryan, N.S.6
  • 17
    • 84876466004 scopus 로고    scopus 로고
    • Systemic inhibition of nitric oxide synthesis in non-diabetic individuals produces a significant deterioration in glucose tolerance by increasing insulin clearance and inhibiting insulin secretion
    • [17] Natali, A., Ribeiro, R., Baldi, S., Tulipani, A., Rossi, M., Venturi, E., Mari, A., Macedo, M.P., Ferrannini, E., Systemic inhibition of nitric oxide synthesis in non-diabetic individuals produces a significant deterioration in glucose tolerance by increasing insulin clearance and inhibiting insulin secretion. Diabetologia 56 (2013), 1183–1191, 10.1007/s00125-013-2836-x.
    • (2013) Diabetologia , vol.56 , pp. 1183-1191
    • Natali, A.1    Ribeiro, R.2    Baldi, S.3    Tulipani, A.4    Rossi, M.5    Venturi, E.6    Mari, A.7    Macedo, M.P.8    Ferrannini, E.9
  • 18
    • 0030852877 scopus 로고    scopus 로고
    • Role of nitric oxide in obesity-induced beta cell disease
    • [18] Shimabukuro, M., Ohneda, M., Lee, Y., Unger, R.H., Role of nitric oxide in obesity-induced beta cell disease. J. Clin. Investigation, 100, 1997, 290, 10.1172/JCI119534.
    • (1997) J. Clin. Investigation , vol.100 , pp. 290
    • Shimabukuro, M.1    Ohneda, M.2    Lee, Y.3    Unger, R.H.4
  • 19
    • 84903541982 scopus 로고    scopus 로고
    • Regulation of obesity and insulin resistance by nitric oxide
    • [19] Sansbury, B.E., Hill, B.G., Regulation of obesity and insulin resistance by nitric oxide. Free Radic. Biol. Med. 73 (2014), 383–399, 10.1016/j.freeradbiomed.2014.05.016.
    • (2014) Free Radic. Biol. Med. , vol.73 , pp. 383-399
    • Sansbury, B.E.1    Hill, B.G.2
  • 21
    • 0030912476 scopus 로고    scopus 로고
    • Components of the AIN-93 diets as improvements in the AIN-76A diet
    • [21] Reeves, P.G., Components of the AIN-93 diets as improvements in the AIN-76A diet. J. Nutr. 127 (1997), 838–841.
    • (1997) J. Nutr. , vol.127 , pp. 838-841
    • Reeves, P.G.1
  • 22
    • 84866092309 scopus 로고    scopus 로고
    • Preanalytical and analytical considerations for measuring nitric oxide metabolites in serum or plasma using the Griess method
    • [22] Ghasemi, A., Zahediasl, S., Preanalytical and analytical considerations for measuring nitric oxide metabolites in serum or plasma using the Griess method. Clin. Lab. 58 (2011), 615–624, 10.7754/Clin.Lab.2011.110908.
    • (2011) Clin. Lab. , vol.58 , pp. 615-624
    • Ghasemi, A.1    Zahediasl, S.2
  • 23
    • 84941933553 scopus 로고    scopus 로고
    • Cut-off points of homeostasis model assessment of insulin resistance, beta-cell function, and fasting serum insulin to identify future type 2 diabetes: Tehran Lipid and Glucose Study
    • [23] Ghasemi, A., Tohidi, M., Derakhshan, A., Hasheminia, M., Azizi, F., Hadaegh, F., Cut-off points of homeostasis model assessment of insulin resistance, beta-cell function, and fasting serum insulin to identify future type 2 diabetes: Tehran Lipid and Glucose Study. Acta diabetol. 52 (2015), 905–915, 10.1007/s00592-015-0730-3.
    • (2015) Acta diabetol. , vol.52 , pp. 905-915
    • Ghasemi, A.1    Tohidi, M.2    Derakhshan, A.3    Hasheminia, M.4    Azizi, F.5    Hadaegh, F.6
  • 24
    • 84897115274 scopus 로고    scopus 로고
    • Age- and sex-specific reference values for fasting serum insulin levels and insulin resistance/sensitivity indices in healthy Iranian adults: Tehran Lipid and Glucose Study
    • [24] Tohidi, M., Ghasemi, A., Hadaegh, F., Derakhshan, A., Chary, A., Azizi, F., Age- and sex-specific reference values for fasting serum insulin levels and insulin resistance/sensitivity indices in healthy Iranian adults: Tehran Lipid and Glucose Study. Clin. Biochem. 47 (2014), 432–438, 10.1016/j.clinbiochem.2014.02.007.
    • (2014) Clin. Biochem. , vol.47 , pp. 432-438
    • Tohidi, M.1    Ghasemi, A.2    Hadaegh, F.3    Derakhshan, A.4    Chary, A.5    Azizi, F.6
  • 25
    • 0014042613 scopus 로고
    • Method for the isolation of intact islets of Langerhans from the rat pancreas
    • [25] Lacy, P.E., Kostianovsky, M., Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 16 (1967), 35–39, 10.2337/diab.16.1.35.
    • (1967) Diabetes , vol.16 , pp. 35-39
    • Lacy, P.E.1    Kostianovsky, M.2
  • 26
    • 84897460002 scopus 로고    scopus 로고
    • The possible mechanisms by which maternal hypothyroidism impairs insulin secretion in adult male offspring in rats
    • [26] Karbalaei, N., Ghasemi, A., Hedayati, M., Godini, A., Zahediasl, S., The possible mechanisms by which maternal hypothyroidism impairs insulin secretion in adult male offspring in rats. Exp. Physiol. 99 (2014), 701–714, 10.1113/expphysiol.2013.073825.
    • (2014) Exp. Physiol. , vol.99 , pp. 701-714
    • Karbalaei, N.1    Ghasemi, A.2    Hedayati, M.3    Godini, A.4    Zahediasl, S.5
  • 27
    • 85013367174 scopus 로고    scopus 로고
    • Effect of nitrate on the body weight, food and water consumption and thyroid hormone in hybrid female rabbits
    • [27] akasha, M., Kerban, A.A., Abobaker, S.a., Effect of nitrate on the body weight, food and water consumption and thyroid hormone in hybrid female rabbits. J. Veterinary Adv. 5 (2015), 912–918, 10.5455/jva.20150517030744.
    • (2015) J. Veterinary Adv. , vol.5 , pp. 912-918
    • akasha, M.1    Kerban, A.A.2    Abobaker, S.A.3
  • 28
    • 84959170246 scopus 로고    scopus 로고
    • SIRT3-AMPK activation by nitrite and metformin improves hyperglycemia and normalizes pulmonary hypertension associated with heart failure with preserved ejection fraction (PH-HFpEF)
    • [28] Lai YC, T.D., Dube, J.J., Hughan, K.S., Vanderpool, R.R., Goncharov, D.A., St Croix, C.M., Garcia-Ocaña, A., Goncharova, E.A., Tofovic, S.P., Mora, A.L., Gladwin, M.T., SIRT3-AMPK activation by nitrite and metformin improves hyperglycemia and normalizes pulmonary hypertension associated with heart failure with preserved ejection fraction (PH-HFpEF). Circulation 133 (2016), 717–731, 10.1161/CIRCULATIONAHA.115.018935.
    • (2016) Circulation , vol.133 , pp. 717-731
    • Lai YC, T.D.1    Dube, J.J.2    Hughan, K.S.3    Vanderpool, R.R.4    Goncharov, D.A.5    St Croix, C.M.6    Garcia-Ocaña, A.7    Goncharova, E.A.8    Tofovic, S.P.9    Mora, A.L.10    Gladwin, M.T.11
  • 29
    • 84921924044 scopus 로고    scopus 로고
    • Inorganic nitrate promotes the browning of white adipose tissue through the nitrate-nitrite-nitric oxide pathway
    • [29] Roberts, L.D., Ashmore, T., Kotwica, A.O., Murfitt, S.A., Fernandez, B.O., Feelisch, M., Murray, A.J., Griffin, J.L., Inorganic nitrate promotes the browning of white adipose tissue through the nitrate-nitrite-nitric oxide pathway. Diabetes 64 (2015), 471–484, 10.2337/db14-0496.
    • (2015) Diabetes , vol.64 , pp. 471-484
    • Roberts, L.D.1    Ashmore, T.2    Kotwica, A.O.3    Murfitt, S.A.4    Fernandez, B.O.5    Feelisch, M.6    Murray, A.J.7    Griffin, J.L.8
  • 30
    • 84903635307 scopus 로고    scopus 로고
    • Comparing the effects of inorganic nitrate and allopurinol in renovascular complications of metabolic syndrome in rats: role of nitric oxide and uric acid
    • [30] Essawy, S.S., Abdel-Sater, K.A., Elbaz, A.A., Comparing the effects of inorganic nitrate and allopurinol in renovascular complications of metabolic syndrome in rats: role of nitric oxide and uric acid. Archives Med. Sci. 10 (2014), 537–545, 10.5114/aoms.2013.33222.
    • (2014) Archives Med. Sci. , vol.10 , pp. 537-545
    • Essawy, S.S.1    Abdel-Sater, K.A.2    Elbaz, A.A.3
  • 33
    • 0030967389 scopus 로고    scopus 로고
    • Nitrite-induced adrenal effects in rats and the consequences for the no-observed-effect level
    • [33] Til, H.P., Kuper, C.F., Falke, H.E., Nitrite-induced adrenal effects in rats and the consequences for the no-observed-effect level. Food Chem. Toxicol. 35 (1997), 349–355.
    • (1997) Food Chem. Toxicol. , vol.35 , pp. 349-355
    • Til, H.P.1    Kuper, C.F.2    Falke, H.E.3
  • 34
    • 55049122402 scopus 로고    scopus 로고
    • Serum nitric oxide metabolites in subjects with metabolic syndrome
    • [34] Zahediasl, S., Ghasemi, A., Azizi, F., Serum nitric oxide metabolites in subjects with metabolic syndrome. Clin. Biochem. 41 (2008), 1342–1347, 10.1016/j.clinbiochem.2008.08.076.
    • (2008) Clin. Biochem. , vol.41 , pp. 1342-1347
    • Zahediasl, S.1    Ghasemi, A.2    Azizi, F.3
  • 35
    • 84989339887 scopus 로고    scopus 로고
    • Nitric oxide levels in patients with diabetes mellitus: a systematic review and meta-analysis
    • S1089-8603(16)30094-5 [pii]
    • [35] Assmann, T.S., Brondani, L.A., Boucas, A.P., Rheinheimer, J., de Souza, B.M., Canani, L.H., Bauer, A.C., Crispim, D., Nitric oxide levels in patients with diabetes mellitus: a systematic review and meta-analysis. Nitric Oxide 61 (2016), 1–9, 10.1016/j.niox.2016.09.009 S1089-8603(16)30094-5 [pii].
    • (2016) Nitric Oxide , vol.61 , pp. 1-9
    • Assmann, T.S.1    Brondani, L.A.2    Boucas, A.P.3    Rheinheimer, J.4    de Souza, B.M.5    Canani, L.H.6    Bauer, A.C.7    Crispim, D.8
  • 37
    • 0027293877 scopus 로고
    • Impaired vasodilator response to atrial natriuretic factor in IDDM
    • [37] Smits, P., Hersbach, F.M.R.J., Jansen, T.L.T.A., Thien, T., Lutterman, J.A., Impaired vasodilator response to atrial natriuretic factor in IDDM. Diabetes 42 (1993), 1454–1461, 10.2337/diab.42.10.1454.
    • (1993) Diabetes , vol.42 , pp. 1454-1461
    • Smits, P.1    Hersbach, F.M.R.J.2    Jansen, T.L.T.A.3    Thien, T.4    Lutterman, J.A.5
  • 38
    • 84921535934 scopus 로고    scopus 로고
    • Circulating and excretory nitrite and nitrate: their value as measures of nitric oxide synthesis, bioavailability and activity is inherently limited
    • [38] Tsikas, D., Circulating and excretory nitrite and nitrate: their value as measures of nitric oxide synthesis, bioavailability and activity is inherently limited. Nitric Oxide 45 (2015), 1–3, 10.1016/j.niox.2015.01.001.
    • (2015) Nitric Oxide , vol.45 , pp. 1-3
    • Tsikas, D.1
  • 39
    • 84909619131 scopus 로고    scopus 로고
    • Pitfalls in measuring NO bioavailability using NOx, nitric oxide
    • [39] Kim-Shapiro, D.B., Gladwin, M.T., Pitfalls in measuring NO bioavailability using NOx, nitric oxide. Biol. Chem./official J. Nitric Oxide Soc. 44 (2015), 1–2, 10.1016/j.niox.2014.10.003.
    • (2015) Biol. Chem./official J. Nitric Oxide Soc. , vol.44 , pp. 1-2
    • Kim-Shapiro, D.B.1    Gladwin, M.T.2
  • 40
    • 0033760442 scopus 로고    scopus 로고
    • Triggering and amplifying pathways of regulation of insulin secretion by glucose
    • [40] Henquin, J.-C., Triggering and amplifying pathways of regulation of insulin secretion by glucose. Diabetes 49 (2000), 1751–1760, 10.2337/diabetes.49.11.1751.
    • (2000) Diabetes , vol.49 , pp. 1751-1760
    • Henquin, J.-C.1
  • 41
    • 84948386691 scopus 로고    scopus 로고
    • Inorganic nitrite improves components of the metabolic syndrome independent of weight change in a murine model of obesity and insulin resistance
    • [41] Singamsetty, S., Watanabe, Y., Guo, L., Corey, C., Wang, Y., Tejero, J., McVerry, B.J., Gladwin, M.T., Shiva, S., O'Donnell, C.P., Inorganic nitrite improves components of the metabolic syndrome independent of weight change in a murine model of obesity and insulin resistance. J. Physiol. 593 (2015), 3135–3145, 10.1113/JP270386.
    • (2015) J. Physiol. , vol.593 , pp. 3135-3145
    • Singamsetty, S.1    Watanabe, Y.2    Guo, L.3    Corey, C.4    Wang, Y.5    Tejero, J.6    McVerry, B.J.7    Gladwin, M.T.8    Shiva, S.9    O'Donnell, C.P.10
  • 42
    • 84890936040 scopus 로고    scopus 로고
    • Nitric oxide vs insulin secretion, action and clearance
    • [42] Kruszelnicka, O., Nitric oxide vs insulin secretion, action and clearance. Diabetologia, 57, 2014, 257, 10.1007/s00125-013-3082-y.
    • (2014) Diabetologia , vol.57 , pp. 257
    • Kruszelnicka, O.1
  • 43
    • 0015335810 scopus 로고
    • Relationship between glucose- and tolbutamide- induced insulin release and insulin content in single pancreatic rat islets
    • [43] Steinke, J., Patel, T.N., Ammon, H.P., Relationship between glucose- and tolbutamide- induced insulin release and insulin content in single pancreatic rat islets. Metabolism 21 (1972), 465–470, 10.1016/0026-0495(72)90058-3.
    • (1972) Metabolism , vol.21 , pp. 465-470
    • Steinke, J.1    Patel, T.N.2    Ammon, H.P.3
  • 44
    • 0030907293 scopus 로고    scopus 로고
    • Parallel reduction of pancreas insulin content and insulin secretion in 48-h tolbutamide-infused normoglycemic rats
    • [44] Hosokawa, Y.A., Leahy, J.L., Parallel reduction of pancreas insulin content and insulin secretion in 48-h tolbutamide-infused normoglycemic rats. Diabetes 46 (1997), 808–813, 10.2337/diab.46.5.808.
    • (1997) Diabetes , vol.46 , pp. 808-813
    • Hosokawa, Y.A.1    Leahy, J.L.2
  • 46
    • 84895418419 scopus 로고    scopus 로고
    • Fenugreek potent activity against nitrate-induced diabetes in young and adult male rats
    • [46] El-Wakf, A.M., Hassan, H.A., Mahmoud, A.Z., Habza, M.N., Fenugreek potent activity against nitrate-induced diabetes in young and adult male rats. Cytotechnology 67 (2015), 437–447, 10.1007/s10616-014-9702-7.
    • (2015) Cytotechnology , vol.67 , pp. 437-447
    • El-Wakf, A.M.1    Hassan, H.A.2    Mahmoud, A.Z.3    Habza, M.N.4
  • 47
    • 85017352811 scopus 로고    scopus 로고
    • Evaluation of the therapeutic effects of nitrite and metformin in a mouse model of pulmonary hypertension associated with heart failure and preserved ejection fraction
    • [47] Meng, Q., Bueno, M., Kelly, N., Lai, Y., Mora, A.L., Gladwin, M.T., Evaluation of the therapeutic effects of nitrite and metformin in a mouse model of pulmonary hypertension associated with heart failure and preserved ejection fraction. Am. J. Respir. Crit. care Med., 193, 2016, A3888.
    • (2016) Am. J. Respir. Crit. care Med. , vol.193 , pp. A3888
    • Meng, Q.1    Bueno, M.2    Kelly, N.3    Lai, Y.4    Mora, A.L.5    Gladwin, M.T.6
  • 48
    • 84896105414 scopus 로고    scopus 로고
    • Nitrite augments glucose uptake in adipocytes through the protein kinase A-dependent stimulation of mitochondrial fusion
    • [48] Khoo, N.K.H., Mo, L., Zharikov, S., Kamga-Pride, C., Quesnelle, K., Golin-Bisello, F., Li, L., Wang, Y., Shiva, S., Nitrite augments glucose uptake in adipocytes through the protein kinase A-dependent stimulation of mitochondrial fusion. Free Radic. Biol. Med. 70 (2014), 45–53, 10.1016/j.freeradbiomed.2014.02.009.
    • (2014) Free Radic. Biol. Med. , vol.70 , pp. 45-53
    • Khoo, N.K.H.1    Mo, L.2    Zharikov, S.3    Kamga-Pride, C.4    Quesnelle, K.5    Golin-Bisello, F.6    Li, L.7    Wang, Y.8    Shiva, S.9
  • 50
    • 84959512158 scopus 로고    scopus 로고
    • Nitrite attenuated peroxynitrite and hypochlorite generation in activated neutrophils
    • S0014-2999(16)30043-7 [pii]
    • [50] Ren, X., Ding, Y., Lu, N., Nitrite attenuated peroxynitrite and hypochlorite generation in activated neutrophils. Eur. J. Pharmacol. 775 (2016), 50–56, 10.1016/j.ejphar.2016.02.020 S0014-2999(16)30043-7 [pii].
    • (2016) Eur. J. Pharmacol. , vol.775 , pp. 50-56
    • Ren, X.1    Ding, Y.2    Lu, N.3
  • 51
    • 84990895374 scopus 로고    scopus 로고
    • Effects of spinach nitrate on insulin resistance, endothelial dysfunction markers and inflammation in mice with high-fat and high-fructose consumption
    • 32010. 32010 [pii]
    • [51] Li, T., Lu, X., Sun, Y., Yang, X., Effects of spinach nitrate on insulin resistance, endothelial dysfunction markers and inflammation in mice with high-fat and high-fructose consumption. Food Nutr. Res., 60, 2016 32010. 32010 [pii].
    • (2016) Food Nutr. Res. , vol.60
    • Li, T.1    Lu, X.2    Sun, Y.3    Yang, X.4
  • 52
    • 84919707452 scopus 로고    scopus 로고
    • Possible role of Interleukin-1β in type 2 diabetes onset and implications for anti-inflammatory therapy strategies
    • [52] Zhao, G., Dharmadhikari, G., Maedler, K., Meyer-Hermann, M., Possible role of Interleukin-1β in type 2 diabetes onset and implications for anti-inflammatory therapy strategies. PLoS Comput. Biol., 10, 2014, e1003798, 10.1371/journal.pcbi.1003798.
    • (2014) PLoS Comput. Biol. , vol.10 , pp. e1003798
    • Zhao, G.1    Dharmadhikari, G.2    Maedler, K.3    Meyer-Hermann, M.4
  • 53
    • 80051474423 scopus 로고    scopus 로고
    • Functional, metabolic, and morphologic characteristics of a novel rat model of type 2 diabetes-associated erectile dysfunction
    • [53] Albersen, M., Lin, G., Fandel, T.M., Zhang, H., Qiu, X., Lin, C.S., Lue, T.F., Functional, metabolic, and morphologic characteristics of a novel rat model of type 2 diabetes-associated erectile dysfunction. Urology 78 (2011), 476.e1–476.e8, 10.1016/j.urology.2011.03.024.
    • (2011) Urology , vol.78 , pp. 476.e1-476.e8
    • Albersen, M.1    Lin, G.2    Fandel, T.M.3    Zhang, H.4    Qiu, X.5    Lin, C.S.6    Lue, T.F.7
  • 55
    • 73449106085 scopus 로고    scopus 로고
    • Role of nitric oxide in the plasma lipid profile in the rabbits
    • [55] Sadeghi-Hashjin, G., Abuhosseini, M., Asri-Rezaei, S., Role of nitric oxide in the plasma lipid profile in the rabbits. Archives Med. Sci. 5 (2009), 308–312.
    • (2009) Archives Med. Sci. , vol.5 , pp. 308-312
    • Sadeghi-Hashjin, G.1    Abuhosseini, M.2    Asri-Rezaei, S.3
  • 56
    • 2942653251 scopus 로고    scopus 로고
    • Upregulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in endothelial cells by nitric oxide deficiency
    • [56] Smirnova, I.V., Sawamura, T., Goligorsky, M.S., Upregulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in endothelial cells by nitric oxide deficiency. Am. J. Physiol. Ren. Physiol. 287 (2004), F25–F32, 10.1152/ajprenal.00449.2003.
    • (2004) Am. J. Physiol. Ren. Physiol. , vol.287 , pp. F25-F32
    • Smirnova, I.V.1    Sawamura, T.2    Goligorsky, M.S.3
  • 58
    • 84890494543 scopus 로고    scopus 로고
    • Role of reduced beta-cell mass versus impaired beta-cell function in the pathogenesis of type 2 diabetes
    • [58] Meier, J.J., Bonadonna, R.C., Role of reduced beta-cell mass versus impaired beta-cell function in the pathogenesis of type 2 diabetes. Diabetes care 36 (2013), S113–S119, 10.2337/dcS13-2008.
    • (2013) Diabetes care , vol.36 , pp. S113-S119
    • Meier, J.J.1    Bonadonna, R.C.2
  • 59
    • 84926679440 scopus 로고    scopus 로고
    • Inorganic nitrite attenuates NADPH oxidase-derived superoxide generation in activated macrophages via a nitric oxide-dependent mechanism
    • [59] Yang, T., Peleli, M., Zollbrecht, C., Giulietti, A., Terrando, N., Lundberg, J.O., Weitzberg, E., Carlstrom, M., Inorganic nitrite attenuates NADPH oxidase-derived superoxide generation in activated macrophages via a nitric oxide-dependent mechanism. Free Radic. Biol. Med. 83 (2015), 159–166, 10.1016/j.freeradbiomed.2015.02.016.
    • (2015) Free Radic. Biol. Med. , vol.83 , pp. 159-166
    • Yang, T.1    Peleli, M.2    Zollbrecht, C.3    Giulietti, A.4    Terrando, N.5    Lundberg, J.O.6    Weitzberg, E.7    Carlstrom, M.8
  • 60
    • 77956518751 scopus 로고    scopus 로고
    • Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis
    • [60] Carter, P., Gray, L.J., Troughton, J., Khunti, K., Davies, M.J., Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis. BMJ, 341, 2010, c4229, 10.1136/bmj.c4229.
    • (2010) BMJ , vol.341 , pp. c4229
    • Carter, P.1    Gray, L.J.2    Troughton, J.3    Khunti, K.4    Davies, M.J.5
  • 61
    • 84952989245 scopus 로고    scopus 로고
    • Dietary inorganic nitrate: from villain to hero in metabolic disease?
    • [61] McNally, B., Griffin, J.L., Roberts, L.D., Dietary inorganic nitrate: from villain to hero in metabolic disease?. Mol. Nutr. Food Res. 60 (2016), 67–78, 10.1002/mnfr.201500153.
    • (2016) Mol. Nutr. Food Res. , vol.60 , pp. 67-78
    • McNally, B.1    Griffin, J.L.2    Roberts, L.D.3
  • 62
    • 84978414661 scopus 로고    scopus 로고
    • Effects of acute dietary nitrate supplementation on aortic blood pressure and aortic augmentation index in young and older adults
    • [62] Hughes, W.E., Ueda, K., Treichler, D.P., Casey, D.P., Effects of acute dietary nitrate supplementation on aortic blood pressure and aortic augmentation index in young and older adults. Nitric Oxide 59 (2016), 21–27, 10.1016/j.niox.2016.06.007.
    • (2016) Nitric Oxide , vol.59 , pp. 21-27
    • Hughes, W.E.1    Ueda, K.2    Treichler, D.P.3    Casey, D.P.4
  • 63
    • 34249279490 scopus 로고    scopus 로고
    • Animal models in type 2 diabetes research: an overview
    • [63] Srinivasan, K., Ramarao, P., Animal models in type 2 diabetes research: an overview. Indian J. Med. Res. 125 (2007), 451–472.
    • (2007) Indian J. Med. Res. , vol.125 , pp. 451-472
    • Srinivasan, K.1    Ramarao, P.2
  • 64
    • 84979299415 scopus 로고    scopus 로고
    • A review of high fat diet-streptozotocin model for induction of type 2 diabetes in rat
    • (in persian)
    • [64] Gheibi, S., Bakhtiarzadeh, F., Ghasemi, A., A review of high fat diet-streptozotocin model for induction of type 2 diabetes in rat. Iran. J. Endocrinol. Metabolism 18 (2016), 135–148 (in persian).
    • (2016) Iran. J. Endocrinol. Metabolism , vol.18 , pp. 135-148
    • Gheibi, S.1    Bakhtiarzadeh, F.2    Ghasemi, A.3
  • 66
    • 84902209796 scopus 로고    scopus 로고
    • Changing paradigms in type 2 diabetes mellitus
    • [66] Khardori, R., Changing paradigms in type 2 diabetes mellitus. Indian J. Endocrinol. Metab. 17 (2013), S68–S71, 10.4103/2230-8210.119509.
    • (2013) Indian J. Endocrinol. Metab. , vol.17 , pp. S68-S71
    • Khardori, R.1
  • 67
    • 84963675332 scopus 로고    scopus 로고
    • Streptozotocin-induced diabetic models in mice and rats
    • [67] Furman, B.L., Streptozotocin-induced diabetic models in mice and rats. Curr. Protoc. Pharmacol. 70 (2015), 5.47.1–5.47.20, 10.1002/0471141755.ph0547s70.
    • (2015) Curr. Protoc. Pharmacol. , vol.70 , pp. 5.47.1-5.47.20
    • Furman, B.L.1
  • 68
    • 0034021464 scopus 로고    scopus 로고
    • The effect of long-term streptozotocin-induced diabetes on contractile and relaxation responses of coronary arteries: selective attenuation of CGRP-induced relaxations
    • [68] Sheykhzade, M., Dalsgaard, G.T., Johansen, T., Nyborg, N.C., The effect of long-term streptozotocin-induced diabetes on contractile and relaxation responses of coronary arteries: selective attenuation of CGRP-induced relaxations. Br. J. Pharmacol. 129 (2000), 1212–1218, 10.1038/sj.bjp.0703159.
    • (2000) Br. J. Pharmacol. , vol.129 , pp. 1212-1218
    • Sheykhzade, M.1    Dalsgaard, G.T.2    Johansen, T.3    Nyborg, N.C.4
  • 69
    • 0036220646 scopus 로고    scopus 로고
    • Alpha-glucosidase inhibition from a Chinese medical herb (Ramulus mori) in normal and diabetic rats and mice
    • S0944-7113(04)70096-3 [pii]
    • [69] Ye, F., Shen, Z., Xie, M., Alpha-glucosidase inhibition from a Chinese medical herb (Ramulus mori) in normal and diabetic rats and mice. Phytomedicine 9 (2002), 161–166, 10.1078/0944-7113-00065 S0944-7113(04)70096-3 [pii].
    • (2002) Phytomedicine , vol.9 , pp. 161-166
    • Ye, F.1    Shen, Z.2    Xie, M.3
  • 70
    • 0025273991 scopus 로고
    • Pentobarbital reduces basal liver glucose output and its insulin suppression in rats
    • [70] Clark, P.W., Jenkins, A.B., Kraegen, E.W., Pentobarbital reduces basal liver glucose output and its insulin suppression in rats. Am. J. Physiol. 258 (1990), E701–E707.
    • (1990) Am. J. Physiol. , vol.258 , pp. E701-E707
    • Clark, P.W.1    Jenkins, A.B.2    Kraegen, E.W.3
  • 71
    • 84872740659 scopus 로고    scopus 로고
    • Effects of anaesthesia on insulin sensitivity and metabolic parameters in Wistar rats
    • [71] Guarino, M.P., Santos, A.I., Mota-Carmo, M., Costa, P.F., Effects of anaesthesia on insulin sensitivity and metabolic parameters in Wistar rats. Vivo 27 (2013), 127–132.
    • (2013) Vivo , vol.27 , pp. 127-132
    • Guarino, M.P.1    Santos, A.I.2    Mota-Carmo, M.3    Costa, P.F.4
  • 72
    • 0028246938 scopus 로고
    • Increased plasma glucose levels after Hypnorm anaesthesia, but not after Pentobarbital anaesthesia in rats
    • [72] Johansen, O., Vaaler, S., Jorde, R., Reikeras, O., Increased plasma glucose levels after Hypnorm anaesthesia, but not after Pentobarbital anaesthesia in rats. Lab. Anim. 28 (1994), 244–248.
    • (1994) Lab. Anim. , vol.28 , pp. 244-248
    • Johansen, O.1    Vaaler, S.2    Jorde, R.3    Reikeras, O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.