Cochlear synaptopathy in acquired sensorineural hearing loss: Manifestations and mechanisms

Hearing Research

Volumn 349, Issue , 2017, Pages 138-147

  Liberman, M Charles ^a,b   Kujawa, Sharon G ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

Author keywords

Auditory nerve; Cochlear neuropathy; Cochlear synaptopathy; Hidden hearing loss; Noise induced hearing loss

Indexed keywords

GLUTAMATE RECEPTOR; GLUTAMIC ACID;

ACOUSTIC NERVE FIBER; ACQUIRED SENSORINEURAL HEARING LOSS; ACTION POTENTIAL; AGING; AUDITORY BRAINSTEM RESPONSE; BRAIN NERVE CELL; BRAIN STEM RESPONSE; COCHLEAR SYNAPTOPATHY; COMPARATIVE STUDY; COMPOUND ACTION POTENTIAL; DISTORTION PRODUCT OTOACOUSTIC EMISSION; EXCITOTOXICITY; EXPERIMENTAL MOUSE; EXPOSURE; GLUTAMATE EXCITOTOXICITY; HEARING; HEARING IMPAIRMENT; HIDDEN HEARING LOSS; HUMAN; INNER EAR DISEASE; LOW SPONTANEOUS RATE NEURON; MORPHOLOGY; NERVE CELL CHARACTERISTICS AND FUNCTIONS; NERVE DEGENERATION; NERVE INJURY; NOISE EXPOSURE; NONHUMAN; OUTCOME ASSESSMENT; OVERT HEARING LOSS; PARAMETERS; PERCEPTION DEAFNESS; PRIORITY JOURNAL; PURE TONE AUDIOMETRY; REVIEW; SYNAPTIC INJURY; SYNAPTIC VULNERABILITY; TEMPORAL BONE; TEMPORARY THRESHOLD SHIFT; TIME SERIES ANALYSIS; ANIMAL; AUDITORY THRESHOLD; COCHLEAR NERVE; INNER HAIR CELL; METABOLISM; NOISE; NOISE INJURY; PATHOLOGY; PATHOPHYSIOLOGY; PSYCHOLOGY; RISK FACTOR; SYNAPSE; SYNAPTIC TRANSMISSION;

ANIMALS; AUDITORY PERCEPTION; AUDITORY THRESHOLD; COCHLEAR NERVE; GLUTAMIC ACID; HAIR CELLS, AUDITORY, INNER; HEARING; HEARING LOSS, NOISE-INDUCED; HEARING LOSS, SENSORINEURAL; HUMANS; NERVE DEGENERATION; NOISE; RISK FACTORS; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 85009809446     PISSN: 03785955     EISSN: 18785891     Source Type: Journal    
DOI: 10.1016/j.heares.2017.01.003     Document Type: Review

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