메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Round-window delivery of neurotrophin 3 regenerates cochlear synapses after acoustic overexposure

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTROPHIN 3;

EID: 84964613641     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep24907     Document Type: Article
Times cited : (172)

References (60)
  • 1
    • 70449643246 scopus 로고    scopus 로고
    • Adding insult to injury: Cochlear nerve degeneration after "temporary" noise-induced hearing loss
    • Kujawa, S. G. & Liberman, M. C. Adding insult to injury: cochlear nerve degeneration after "temporary" noise-induced hearing loss. J Neurosci 29, 14077-14085 (2009).
    • (2009) J Neurosci , vol.29 , pp. 14077-14085
    • Kujawa, S.G.1    Liberman, M.C.2
  • 3
    • 34248209558 scopus 로고    scopus 로고
    • Primary afferent dendrite degeneration as a cause of tinnitus
    • Bauer, C. A., Brozoski, T. J. & Myers, K. Primary afferent dendrite degeneration as a cause of tinnitus. J Neurosci Res 85, 1489-1498 (2007).
    • (2007) J Neurosci Res , vol.85 , pp. 1489-1498
    • Bauer, C.A.1    Brozoski, T.J.2    Myers, K.3
  • 4
    • 84874846057 scopus 로고    scopus 로고
    • The reduced cochlear output and the failure to adapt the central auditory response causes tinnitus in noise exposed rats
    • Ruttiger, L. et al. The reduced cochlear output and the failure to adapt the central auditory response causes tinnitus in noise exposed rats. Plos One 8, e57247 (2013).
    • (2013) Plos One , vol.8
    • Ruttiger, L.1
  • 5
    • 80053003469 scopus 로고    scopus 로고
    • Tinnitus with a normal audiogram: Physiological evidence for hidden hearing loss and computational model
    • Schaette, R. & McAlpine, D. Tinnitus with a normal audiogram: physiological evidence for hidden hearing loss and computational model. J Neurosci 31, 13452-13457 (2011).
    • (2011) J Neurosci , vol.31 , pp. 13452-13457
    • Schaette, R.1    McAlpine, D.2
  • 6
    • 0019424099 scopus 로고
    • Spiral ganglion neuron loss following organ of Corti loss: A quantitative study
    • Webster, M. & Webster, D. B. Spiral ganglion neuron loss following organ of Corti loss: a quantitative study. Brain research 212, 17-30 (1981).
    • (1981) Brain Research , vol.212 , pp. 17-30
    • Webster, M.1    Webster, D.B.2
  • 7
  • 8
    • 0016230101 scopus 로고
    • Sequence of degeneration of Corti's organ and its first-order neurons
    • Johnsson, L. G. Sequence of degeneration of Corti's organ and its first-order neurons. Ann Otol Rhinol Laryngol 83, 294-303 (1974).
    • (1974) Ann Otol Rhinol Laryngol , vol.83 , pp. 294-303
    • Johnsson, L.G.1
  • 9
    • 0018066811 scopus 로고
    • Acoustic trauma in cats. Cochlear pathology and auditory-nerve activity
    • Liberman, M. C. & Kiang, N. Y. Acoustic trauma in cats. Cochlear pathology and auditory-nerve activity. Acta Otolaryngol Suppl 358, 1-63 (1978).
    • (1978) Acta Otolaryngol Suppl , vol.358 , pp. 1-63
    • Liberman, M.C.1    Kiang, N.Y.2
  • 11
    • 0034927081 scopus 로고    scopus 로고
    • Neurotrophins: Roles in neuronal development and function
    • Huang, E. J. & Reichardt, L. F. Neurotrophins: roles in neuronal development and function. Annu Rev Neurosci 24, 677-736 (2001).
    • (2001) Annu Rev Neurosci , vol.24 , pp. 677-736
    • Huang, E.J.1    Reichardt, L.F.2
  • 12
    • 84861875641 scopus 로고    scopus 로고
    • Neurotrophins and their role in the cochlea
    • Ramekers, D., Versnel, H., Grolman, W. & Klis, S. F. Neurotrophins and their role in the cochlea. Hear Res 288, 19-33 (2012).
    • (2012) Hear Res , vol.288 , pp. 19-33
    • Ramekers, D.1    Versnel, H.2    Grolman, W.3    Klis, S.F.4
  • 13
    • 0035882477 scopus 로고    scopus 로고
    • Spatial shaping of cochlear innervation by temporally regulated neurotrophin expression
    • Farinas, I. et al. Spatial shaping of cochlear innervation by temporally regulated neurotrophin expression. J Neurosci 21, 6170-6180 (2001).
    • (2001) J Neurosci , vol.21 , pp. 6170-6180
    • Farinas, I.1
  • 14
    • 0026657074 scopus 로고
    • Brain-derived neurotrophic factor and neurotrophin 3 mRNAs in the peripheral target fields of developing inner ear ganglia
    • Pirvola, U. et al. Brain-derived neurotrophic factor and neurotrophin 3 mRNAs in the peripheral target fields of developing inner ear ganglia. Proc Natl Acad Sci USA 89, 9915-9919 (1992).
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9915-9919
    • Pirvola, U.1
  • 15
    • 0029014667 scopus 로고
    • Complementary roles of BDNF and NT-3 in vestibular and auditory development
    • Ernfors, P., Van De Water, T., Loring, J. & Jaenisch, R. Complementary roles of BDNF and NT-3 in vestibular and auditory development. Neuron 14, 1153-1164 (1995).
    • (1995) Neuron , vol.14 , pp. 1153-1164
    • Ernfors, P.1    Van De Water, T.2    Loring, J.3    Jaenisch, R.4
  • 16
    • 0028274040 scopus 로고
    • Mice lacking brain-derived neurotrophic factor develop with sensory deficits
    • Ernfors, P., Lee, K. F. & Jaenisch, R. Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature 368, 147-150 (1994).
    • (1994) Nature , vol.368 , pp. 147-150
    • Ernfors, P.1    Lee, K.F.2    Jaenisch, R.3
  • 17
    • 84930654678 scopus 로고    scopus 로고
    • Neurotrophin-3 regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma
    • Wan, G., Gomez-Casati, M. E., Gigliello, A. R., Liberman, M. C. & Corfas, G. Neurotrophin-3 regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma. eLife 3 (2014).
    • (2014) eLife , vol.3
    • Wan, G.1    Gomez-Casati, M.E.2    Gigliello, A.R.3    Liberman, M.C.4    Corfas, G.5
  • 18
    • 33846542432 scopus 로고    scopus 로고
    • Dynamic patterns of neurotrophin 3 expression in the postnatal mouse inner ear
    • Sugawara, M., Murtie, J. C., Stankovic, K. M., Liberman, M. C. & Corfas, G. Dynamic patterns of neurotrophin 3 expression in the postnatal mouse inner ear. J Comp Neurol 501, 30-37 (2007).
    • (2007) J Comp Neurol , vol.501 , pp. 30-37
    • Sugawara, M.1    Murtie, J.C.2    Stankovic, K.M.3    Liberman, M.C.4    Corfas, G.5
  • 19
    • 84867899587 scopus 로고    scopus 로고
    • The Trk A, B, C's of neurotrophins in the cochlea
    • Green, S. H., Bailey, E., Wang, Q. & Davis, R. L. The Trk A, B, C's of neurotrophins in the cochlea. Anatomical Record 295, 1877-1895 (2012).
    • (2012) Anatomical Record , vol.295 , pp. 1877-1895
    • Green, S.H.1    Bailey, E.2    Wang, Q.3    Davis, R.L.4
  • 21
    • 84856393445 scopus 로고    scopus 로고
    • Intratympanic steroids for sudden sensorineural hearing loss: A systematic review
    • Spear, S. A. & Schwartz, S. R. Intratympanic steroids for sudden sensorineural hearing loss: a systematic review. Otolaryngol Head Neck Surg 145, 534-543 (2011).
    • (2011) Otolaryngol Head Neck Surg , vol.145 , pp. 534-543
    • Spear, S.A.1    Schwartz, S.R.2
  • 22
    • 84939567255 scopus 로고    scopus 로고
    • Dynamics of cochlear synaptopathy after acoustic overexposure
    • Liberman, L. D., Suzuki, J. & Liberman, M. C. Dynamics of cochlear synaptopathy after acoustic overexposure. J Assoc Res Otolaryngol 16, 205-219 (2015).
    • (2015) J Assoc Res Otolaryngol , vol.16 , pp. 205-219
    • Liberman, L.D.1    Suzuki, J.2    Liberman, M.C.3
  • 23
    • 0014474531 scopus 로고
    • Innervation patterns in the organ of corti of the cat
    • Spoendlin, H. Innervation patterns in the organ of corti of the cat. Acta Otolaryngol 67, 239-254 (1969).
    • (1969) Acta Otolaryngol , vol.67 , pp. 239-254
    • Spoendlin, H.1
  • 24
    • 0015291947 scopus 로고
    • Innervation densities of the cochlea
    • Spoendlin, H. H. Innervation densities of the cochlea. Acta Otolaryngol 73, 235-248 (1972).
    • (1972) Acta Otolaryngol , vol.73 , pp. 235-248
    • Spoendlin, H.H.1
  • 25
    • 0019312709 scopus 로고
    • Morphological differences among radial afferent fibers in the cat cochlea: An electron-microscopic study of serial sections
    • Liberman, M. C. Morphological differences among radial afferent fibers in the cat cochlea: An electron-microscopic study of serial sections. Hear Res 3, 45-63 (1980).
    • (1980) Hear Res , vol.3 , pp. 45-63
    • Liberman, M.C.1
  • 26
    • 84880985531 scopus 로고    scopus 로고
    • Noise-induced cochlear neuropathy is selective for fibers with low spontaneous rates
    • Furman, A. C., Kujawa, S. G. & Liberman, M. C. Noise-induced cochlear neuropathy is selective for fibers with low spontaneous rates. J Neurophysiol 110, 577-586 (2013).
    • (2013) J Neurophysiol , vol.110 , pp. 577-586
    • Furman, A.C.1    Kujawa, S.G.2    Liberman, M.C.3
  • 27
    • 0343471382 scopus 로고    scopus 로고
    • Lack of neurotrophin 3 causes losses of both classes of spiral ganglion neurons in the cochlea in a region-specific fashion
    • Fritzsch, B., Farinas, I. & Reichardt, L. F. Lack of neurotrophin 3 causes losses of both classes of spiral ganglion neurons in the cochlea in a region-specific fashion. J Neurosci 17, 6213-6225 (1997).
    • (1997) J Neurosci , vol.17 , pp. 6213-6225
    • Fritzsch, B.1    Farinas, I.2    Reichardt, L.F.3
  • 28
    • 0242289297 scopus 로고    scopus 로고
    • Real-time quantitative RT-PCR for low-abundance transcripts in the inner ear: Analysis of neurotrophic factor expression
    • Stankovic, K. M. & Corfas, G. Real-time quantitative RT-PCR for low-abundance transcripts in the inner ear: analysis of neurotrophic factor expression. Hear Res 185, 97-108 (2003).
    • (2003) Hear Res , vol.185 , pp. 97-108
    • Stankovic, K.M.1    Corfas, G.2
  • 29
    • 84907298247 scopus 로고    scopus 로고
    • Postnatal expression of neurotrophic factors accessible to spiral ganglion neurons in the auditory system of adult hearing and deafened rats
    • Bailey, E. M. & Green, S. H. Postnatal expression of neurotrophic factors accessible to spiral ganglion neurons in the auditory system of adult hearing and deafened rats. J Neurosci 34, 13110-13126 (2014).
    • (2014) J Neurosci , vol.34 , pp. 13110-13126
    • Bailey, E.M.1    Green, S.H.2
  • 30
    • 78049314066 scopus 로고    scopus 로고
    • Nonneuronal cells regulate synapse formation in the vestibular sensory epithelium via erbB-dependent BDNF expression
    • Gomez-Casati, M. E. et al. Nonneuronal cells regulate synapse formation in the vestibular sensory epithelium via erbB-dependent BDNF expression. Proc Natl Acad Sci USA 107, 17005-17010 (2010).
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 17005-17010
    • Gomez-Casati, M.E.1
  • 31
    • 82755182875 scopus 로고    scopus 로고
    • Spiral ganglion neuron survival and function in the deafened cochlea following chronic neurotrophic treatment
    • Landry, T. G., Wise, A. K., Fallon, J. B. & Shepherd, R. K. Spiral ganglion neuron survival and function in the deafened cochlea following chronic neurotrophic treatment. Hear Res 282, 303-313 (2011).
    • (2011) Hear Res , vol.282 , pp. 303-313
    • Landry, T.G.1    Wise, A.K.2    Fallon, J.B.3    Shepherd, R.K.4
  • 32
    • 0030837816 scopus 로고    scopus 로고
    • Neurotrophins can enhance spiral ganglion cell survival after inner hair cell loss
    • Miller, J. M. et al. Neurotrophins can enhance spiral ganglion cell survival after inner hair cell loss. Int J Dev Neurosci 15, 631-643 (1997).
    • (1997) Int J Dev Neurosci , vol.15 , pp. 631-643
    • Miller, J.M.1
  • 33
    • 18644383345 scopus 로고    scopus 로고
    • A single dose of neurotrophin-3 to the cochlea surrounds spiral ganglion neurons and provides trophic support
    • Richardson, R. T., O'Leary, S., Wise, A., Hardman, J. & Clark, G. A single dose of neurotrophin-3 to the cochlea surrounds spiral ganglion neurons and provides trophic support. Hear Res 204, 37-47 (2005).
    • (2005) Hear Res , vol.204 , pp. 37-47
    • Richardson, R.T.1    O'Leary, S.2    Wise, A.3    Hardman, J.4    Clark, G.5
  • 34
    • 19544383410 scopus 로고    scopus 로고
    • Resprouting and survival of guinea pig cochlear neurons in response to the administration of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3
    • Wise, A. K., Richardson, R., Hardman, J., Clark, G. & O'Leary, S. Resprouting and survival of guinea pig cochlear neurons in response to the administration of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3. J Comp Neurol 487, 147-165 (2005).
    • (2005) J Comp Neurol , vol.487 , pp. 147-165
    • Wise, A.K.1    Richardson, R.2    Hardman, J.3    Clark, G.4    O'Leary, S.5
  • 35
    • 84923899698 scopus 로고    scopus 로고
    • Differential effects of AAV.BDNF and AAV.Ntf3 in the deafened adult guinea pig ear
    • Budenz, C. L. et al. Differential effects of AAV.BDNF and AAV.Ntf3 in the deafened adult guinea pig ear. Sci Rep 5, 8619 (2015).
    • (2015) Sci Rep , vol.5 , pp. 8619
    • Budenz, C.L.1
  • 36
    • 84855680854 scopus 로고    scopus 로고
    • Inner hair cells are not required for survival of spiral ganglion neurons in the adult cochlea
    • Zilberstein, Y., Liberman, M. C. & Corfas, G. Inner hair cells are not required for survival of spiral ganglion neurons in the adult cochlea. J Neurosci 32, 405-410 (2012).
    • (2012) J Neurosci , vol.32 , pp. 405-410
    • Zilberstein, Y.1    Liberman, M.C.2    Corfas, G.3
  • 37
    • 84882720760 scopus 로고    scopus 로고
    • Age-related cochlear synaptopathy: An early-onset contributor to auditory functional decline
    • Sergeyenko, Y., Lall, K., Liberman, M. C. & Kujawa, S. G. Age-related cochlear synaptopathy: an early-onset contributor to auditory functional decline. J Neurosci 33, 13686-13694 (2013).
    • (2013) J Neurosci , vol.33 , pp. 13686-13694
    • Sergeyenko, Y.1    Lall, K.2    Liberman, M.C.3    Kujawa, S.G.4
  • 38
    • 84891121773 scopus 로고    scopus 로고
    • Topographic and quantitative evaluation of gentamicin-induced damage to peripheral innervation of mouse cochleae
    • Ruan, Q. et al. Topographic and quantitative evaluation of gentamicin-induced damage to peripheral innervation of mouse cochleae. Neurotoxicology 40, 86-96 (2014).
    • (2014) Neurotoxicology , vol.40 , pp. 86-96
    • Ruan, Q.1
  • 39
    • 84929353520 scopus 로고    scopus 로고
    • Aging after noise exposure: Acceleration of cochlear synaptopathy in "recovered" ears
    • Fernandez, K. A., Jeffers, P. W., Lall, K., Liberman, M. C. & Kujawa, S. G. Aging after noise exposure: acceleration of cochlear synaptopathy in "recovered" ears. J Neurosci 35, 7509-7520 (2015).
    • (2015) J Neurosci , vol.35 , pp. 7509-7520
    • Fernandez, K.A.1    Jeffers, P.W.2    Lall, K.3    Liberman, M.C.4    Kujawa, S.G.5
  • 40
    • 0020666084 scopus 로고
    • Functional significance of dendritic swelling after loud sounds in the guinea pig cochlea
    • Robertson, D. Functional significance of dendritic swelling after loud sounds in the guinea pig cochlea. Hear Res. 9, 263-278 (1983).
    • (1983) Hear Res. , vol.9 , pp. 263-278
    • Robertson, D.1
  • 42
    • 0027191971 scopus 로고
    • Pathophysiology of the glutamatergic synapses in the cochlea
    • Pujol, R., Puel, J. L., Gervais d'Aldin, C. & Eybalin, M. Pathophysiology of the glutamatergic synapses in the cochlea. Acta Otolaryngol 113, 330-334 (1993).
    • (1993) Acta Otolaryngol , vol.113 , pp. 330-334
    • Pujol, R.1    Puel, J.L.2    Gervais D'Aldin, C.3    Eybalin, M.4
  • 43
    • 79957634907 scopus 로고    scopus 로고
    • Functional role of neurotrophin-3 in synapse regeneration by spiral ganglion neurons on inner hair cells after excitotoxic trauma in vitro
    • Wang, Q. & Green, S. H. Functional role of neurotrophin-3 in synapse regeneration by spiral ganglion neurons on inner hair cells after excitotoxic trauma in vitro. J Neurosci 31, 7938-7949 (2011).
    • (2011) J Neurosci , vol.31 , pp. 7938-7949
    • Wang, Q.1    Green, S.H.2
  • 45
    • 0028826474 scopus 로고
    • Chronic cochlear de-efferentation and susceptibility to permanent acoustic injury
    • Liberman, M. C. & Gao, W. Y. Chronic cochlear de-efferentation and susceptibility to permanent acoustic injury. Hear Res 90, 158-168 (1995).
    • (1995) Hear Res , vol.90 , pp. 158-168
    • Liberman, M.C.1    Gao, W.Y.2
  • 46
    • 0036750638 scopus 로고    scopus 로고
    • Dynamics of noise-induced cellular injury and repair in the mouse cochlea
    • Wang, Y., Hirose, K. & Liberman, M. C. Dynamics of noise-induced cellular injury and repair in the mouse cochlea. J Assoc Res Otolaryngol 3, 248-268 (2002).
    • (2002) J Assoc Res Otolaryngol , vol.3 , pp. 248-268
    • Wang, Y.1    Hirose, K.2    Liberman, M.C.3
  • 48
    • 0033926469 scopus 로고    scopus 로고
    • Differential protective effects of neurotrophins in the attenuation of noise-induced hair cell loss
    • Shoji, F. et al. Differential protective effects of neurotrophins in the attenuation of noise-induced hair cell loss. Hear Res 146, 134-142 (2000).
    • (2000) Hear Res , vol.146 , pp. 134-142
    • Shoji, F.1
  • 49
    • 0033551575 scopus 로고    scopus 로고
    • Effects of BDNF and NT-3 on hair cell survival in guinea pig cochlea damaged by kanamycin treatment
    • Ruan, R. S., Leong, S. K., Mark, I. & Yeoh, K. H. Effects of BDNF and NT-3 on hair cell survival in guinea pig cochlea damaged by kanamycin treatment. Neuroreport 10, 2067-2071 (1999).
    • (1999) Neuroreport , vol.10 , pp. 2067-2071
    • Ruan, R.S.1    Leong, S.K.2    Mark, I.3    Yeoh, K.H.4
  • 50
    • 21244499414 scopus 로고    scopus 로고
    • Influence of supporting cells on neuronal degeneration after hair cell loss
    • Sugawara, M., Corfas, G. & Liberman, M. C. Influence of supporting cells on neuronal degeneration after hair cell loss. J Assoc Res Otolaryngol 6, 136-147 (2005).
    • (2005) J Assoc Res Otolaryngol , vol.6 , pp. 136-147
    • Sugawara, M.1    Corfas, G.2    Liberman, M.C.3
  • 51
    • 84879603333 scopus 로고    scopus 로고
    • Insensitivity of the audiogram to carboplatin induced inner hair cell loss in chinchillas
    • Lobarinas, E., Salvi, R. & Ding, D. Insensitivity of the audiogram to carboplatin induced inner hair cell loss in chinchillas. Hear Res 302, 113-120 (2013).
    • (2013) Hear Res , vol.302 , pp. 113-120
    • Lobarinas, E.1    Salvi, R.2    Ding, D.3
  • 52
    • 84960991869 scopus 로고
    • An experimental and clinical study of deafness from lesions of the cochlear nerve
    • Schuknecht, H. F. & Woellner, R. C. An experimental and clinical study of deafness from lesions of the cochlear nerve. J Laryngol Otol 69, 75-97 (1955).
    • (1955) J Laryngol Otol , vol.69 , pp. 75-97
    • Schuknecht, H.F.1    Woellner, R.C.2
  • 53
    • 84930651549 scopus 로고    scopus 로고
    • Cochlear neuropathy in human presbycusis: Confocal analysis of hidden hearing loss in post-mortem tissue
    • Viana, L. M. et al. Cochlear neuropathy in human presbycusis: Confocal analysis of hidden hearing loss in post-mortem tissue. Hear Res 327, 78-88 (2015).
    • (2015) Hear Res , vol.327 , pp. 78-88
    • Viana, L.M.1
  • 54
    • 0029585204 scopus 로고
    • Quantitative evaluation of myelinated nerve fibres and hair cells in cochleae of humans with age-related high-tone hearing loss
    • Felder, E. & Schrott-Fischer, A. Quantitative evaluation of myelinated nerve fibres and hair cells in cochleae of humans with age-related high-tone hearing loss. Hear Res 91, 19-32 (1995).
    • (1995) Hear Res , vol.91 , pp. 19-32
    • Felder, E.1    Schrott-Fischer, A.2
  • 55
    • 78149489680 scopus 로고    scopus 로고
    • Ringing ears: The neuroscience of tinnitus
    • Roberts, L. E. et al. Ringing ears: the neuroscience of tinnitus. J Neurosci 30, 14972-14979 (2010).
    • (2010) J Neurosci , vol.30 , pp. 14972-14979
    • Roberts, L.E.1
  • 56
    • 84920615914 scopus 로고    scopus 로고
    • Restoring synaptic connections in the inner ear after noise damage
    • Cunningham, L. L. & Tucci, D. L. Restoring synaptic connections in the inner ear after noise damage. N Engl J Med 372, 181-182 (2015).
    • (2015) N Engl J Med , vol.372 , pp. 181-182
    • Cunningham, L.L.1    Tucci, D.L.2
  • 57
    • 78650238229 scopus 로고    scopus 로고
    • Distribution of dexamethasone and preservation of inner ear function following intratympanic delivery of a gel-based formulation
    • Salt, A. N., Hartsock, J., Plontke, S., LeBel, C. & Piu, F. Distribution of dexamethasone and preservation of inner ear function following intratympanic delivery of a gel-based formulation. Audiol & Neurotol 16, 323-335 (2011).
    • (2011) Audiol & Neurotol , vol.16 , pp. 323-335
    • Salt, A.N.1    Hartsock, J.2    Plontke, S.3    LeBel, C.4    Piu, F.5
  • 58
    • 0029928170 scopus 로고    scopus 로고
    • Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF
    • Poduslo, J. F. & Curran, G. L. Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF. Brain Res Mol Brain Res 36, 280-286 (1996).
    • (1996) Brain Res Mol Brain Res , vol.36 , pp. 280-286
    • Poduslo, J.F.1    Curran, G.L.2
  • 60
    • 84940173805 scopus 로고    scopus 로고
    • Synaptopathy in the noise-exposed and aging cochlea: Primary neural degeneration in acquired sensorineural hearing loss
    • Kujawa, S. G. & Liberman, M. C. Synaptopathy in the noise-exposed and aging cochlea: Primary neural degeneration in acquired sensorineural hearing loss. Hear Res 330, 191-199 (2015).
    • (2015) Hear Res , vol.330 , pp. 191-199
    • Kujawa, S.G.1    Liberman, M.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.