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Volumn 6, Issue DEC, 2016, Pages

β-glucan exposure on the fungal cell wall tightly correlates with competitive fitness of Candida species in the mouse gastrointestinal tract

Author keywords

Beta glucan; Candida; Candida albicans; Cell wall; Competitive fitness; Dectin 1; Gastrointestinal tract

Indexed keywords

BETA GLUCAN; DECTIN 1; GENOMIC DNA; LECTIN;

EID: 85009789214     PISSN: None     EISSN: 22352988     Source Type: Journal    
DOI: 10.3389/fcimb.2016.00186     Document Type: Article
Times cited : (41)

References (44)
  • 1
    • 84857185773 scopus 로고    scopus 로고
    • High-resolution SNP/CGH microarrays reveal the accumulation of loss of heterozygosity in commonly used Candida albicans strains
    • Abbey, D., Hickman, M., Gresham, D., and Berman, J. (2011). High-resolution SNP/CGH microarrays reveal the accumulation of loss of heterozygosity in commonly used Candida albicans strains. G3 1, 523-530. doi: 10.1534/g3.111.000885
    • (2011) G3 , vol.1 , pp. 523-530
    • Abbey, D.1    Hickman, M.2    Gresham, D.3    Berman, J.4
  • 2
    • 33644867152 scopus 로고    scopus 로고
    • Outer chain N-glycans are required for cell wall integrity and virulence of Candida albicans
    • Bates, S., Hughes, H. B., Munro, C. A., Thomas, W. P., Maccallum, D. M., Bertram, G., et al. (2006). Outer chain N-glycans are required for cell wall integrity and virulence of Candida albicans. J. Biol. Chem. 281, 90-98. doi: 10.1074/jbc.M510360200
    • (2006) J. Biol. Chem , vol.281 , pp. 90-98
    • Bates, S.1    Hughes, H.B.2    Munro, C.A.3    Thomas, W.P.4    Maccallum, D.M.5    Bertram, G.6
  • 3
    • 20744455345 scopus 로고    scopus 로고
    • Candida albicans Pmr1p, a secretory pathway P-type Ca2+/Mn2+-ATPase, is required for glycosylation and virulence
    • Bates, S., Maccallum, D. M., Bertram, G., Munro, C. A., Hughes, H. B., Buurman, E. T., et al. (2005). Candida albicans Pmr1p, a secretory pathway P-type Ca2+/Mn2+-ATPase, is required for glycosylation and virulence. J. Biol. Chem. 280, 23408-23415. doi: 10.1074/jbc.M502162200
    • (2005) J. Biol. Chem , vol.280 , pp. 23408-23415
    • Bates, S.1    Maccallum, D.M.2    Bertram, G.3    Munro, C.A.4    Hughes, H.B.5    Buurman, E.T.6
  • 4
    • 79960884598 scopus 로고    scopus 로고
    • Fitness and virulence costs of Candida albicans FKS1 hot spot mutations associated with echinocandin resistance
    • Ben-Ami, R., Garcia-Effron, G., Lewis, R. E., Gamarra, S., Leventakos, K., Perlin, D. S., et al. (2011). Fitness and virulence costs of Candida albicans FKS1 hot spot mutations associated with echinocandin resistance. J. Infect. Dis. 204, 626-635. doi: 10.1093/infdis/jir351
    • (2011) J. Infect. Dis , vol.204 , pp. 626-635
    • Ben-Ami, R.1    Garcia-Effron, G.2    Lewis, R.E.3    Gamarra, S.4    Leventakos, K.5    Perlin, D.S.6
  • 7
    • 0028839336 scopus 로고
    • Attenuated virulence of chitin-deficient mutants of Candida albicans
    • Bulawa, C. E., Miller, D. W., Henry, L. K., and Becker, J. M. (1995). Attenuated virulence of chitin-deficient mutants of Candida albicans. Proc. Natl. Acad. Sci. U.S.A. 92, 10570-10574. doi: 10.1073/pnas.92.23.10570
    • (1995) Proc. Natl. Acad. Sci. U.S.A , vol.92 , pp. 10570-10574
    • Bulawa, C.E.1    Miller, D.W.2    Henry, L.K.3    Becker, J.M.4
  • 9
    • 41449100303 scopus 로고    scopus 로고
    • CTA4 transcription factor mediates induction of nitrosative stress response in Candida albicans
    • Chiranand, W., McLeod, I., Zhou, H., Lynn, J. J., Vega, L. A., Myers, H., et al. (2008). CTA4 transcription factor mediates induction of nitrosative stress response in Candida albicans. Eukaryot Cell 7, 268-278. doi: 10.1128/EC.00240-07
    • (2008) Eukaryot Cell , vol.7 , pp. 268-278
    • Chiranand, W.1    McLeod, I.2    Zhou, H.3    Lynn, J.J.4    Vega, L.A.5    Myers, H.6
  • 10
    • 84928995941 scopus 로고    scopus 로고
    • The transcriptional stress response of Candida albicans to weak organic acids
    • Cottier, F., Tan, A. S., Chen, J., Lum, J., Zolezzi, F., Poidinger, M., et al. (2015a). The transcriptional stress response of Candida albicans to weak organic acids. G3 5, 497-505. doi: 10.1534/g3.114.015941
    • (2015) G3 , vol.5 , pp. 497-505
    • Cottier, F.1    Tan, A.S.2    Chen, J.3    Lum, J.4    Zolezzi, F.5    Poidinger, M.6
  • 11
    • 84942885774 scopus 로고    scopus 로고
    • MIG1 regulates resistance of Candida albicans against the fungistatic effect of weak organic acids
    • Cottier, F., Tan, A. S., Xu, X., Wang, Y., and Pavelka, N. (2015b). MIG1 regulates resistance of Candida albicans against the fungistatic effect of weak organic acids. Eukaryot Cell 14, 1054-1061. doi: 10.1128/EC.00129-15
    • (2015) Eukaryot Cell , vol.14 , pp. 1054-1061
    • Cottier, F.1    Tan, A.S.2    Xu, X.3    Wang, Y.4    Pavelka, N.5
  • 12
    • 0029929759 scopus 로고    scopus 로고
    • The KNH1 gene of Saccharomyces cerevisiae is a functional homolog of KRE9
    • Dijkgraaf, G. J., Brown, J. L., and Bussey, H. (1996). The KNH1 gene of Saccharomyces cerevisiae is a functional homolog of KRE9. Yeast 12, 683-692. doi: 10.1002/(SICI)1097-0061(19960615)12:7<683::AID-YEA959>3.0.CO;2-8
    • (1996) Yeast , vol.12 , pp. 683-692
    • Dijkgraaf, G.J.1    Brown, J.L.2    Bussey, H.3
  • 13
    • 33749946901 scopus 로고
    • Colorimetric method for determination of sugars and related substances
    • Dubois, M., Gilles, K. A., Hamilton, J. K., Rebers, P. A., and Smith, F. (1956). Colorimetric method for determination of sugars and related substances. Anal. Chem. 28, 350-356. doi: 10.1021/ac60111a017
    • (1956) Anal. Chem , vol.28 , pp. 350-356
    • Dubois, M.1    Gilles, K.A.2    Hamilton, J.K.3    Rebers, P.A.4    Smith, F.5
  • 14
    • 84936891126 scopus 로고    scopus 로고
    • Activation of HIF-1[alpha] and LL-37 by commensal bacteria inhibits Candida albicans colonization
    • Fan, D., Coughlin, L. A., Neubauer, M. M., Kim, J., Kim, M. S., Zhan, X., et al. (2015). Activation of HIF-1[alpha] and LL-37 by commensal bacteria inhibits Candida albicans colonization. Nat. Med. 21, 808-814. doi: 10.1038/nm.3871
    • (2015) Nat. Med , vol.21 , pp. 808-814
    • Fan, D.1    Coughlin, L.A.2    Neubauer, M.M.3    Kim, J.4    Kim, M.S.5    Zhan, X.6
  • 15
    • 84865307122 scopus 로고    scopus 로고
    • Importance of the Candida albicans cell wall during commensalism and infection
    • Gow, N. A., and Hube, B. (2012). Importance of the Candida albicans cell wall during commensalism and infection. Curr. Opin. Microbiol. 15, 406-412. doi: 10.1016/j.mib.2012.04.005
    • (2012) Curr. Opin. Microbiol , vol.15 , pp. 406-412
    • Gow, N.A.1    Hube, B.2
  • 16
  • 17
    • 4544309392 scopus 로고    scopus 로고
    • Loss of cell wall mannosylphosphate in Candida albicans does not influence macrophage recognition
    • Hobson, R. P., Munro, C. A., Bates, S., Maccallum, D. M., Cutler, J. E., Heinsbroek, S. E., et al. (2004). Loss of cell wall mannosylphosphate in Candida albicans does not influence macrophage recognition. J. Biol. Chem. 279, 39628-39635. doi: 10.1074/jbc.M405003200
    • (2004) J. Biol. Chem , vol.279 , pp. 39628-39635
    • Hobson, R.P.1    Munro, C.A.2    Bates, S.3    Maccallum, D.M.4    Cutler, J.E.5    Heinsbroek, S.E.6
  • 18
    • 84861964286 scopus 로고    scopus 로고
    • Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis
    • Iliev, I. D., Funari, V. A., Taylor, K. D., Nguyen, Q., Reyes, C. N., Strom, S. P., et al. (2012). Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis. Science 336, 1314-1317. doi: 10.1126/science.1221789
    • (2012) Science , vol.336 , pp. 1314-1317
    • Iliev, I.D.1    Funari, V.A.2    Taylor, K.D.3    Nguyen, Q.4    Reyes, C.N.5    Strom, S.P.6
  • 19
    • 0030844713 scopus 로고    scopus 로고
    • Altered extent of cross-linking of beta1,6-glucosylated mannoproteins to chitin in Saccharomyces cerevisiae mutants with reduced cell wall beta1,3-glucan content
    • Kapteyn, J. C., Ram, A. F., Groos, E. M., Kollar, R., Montijn, R. C., Van Den Ende, H., et al. (1997). Altered extent of cross-linking of beta1,6-glucosylated mannoproteins to chitin in Saccharomyces cerevisiae mutants with reduced cell wall beta1,3-glucan content. J. Bacteriol. 179, 6279-6284. doi: 10.1128/jb.179.20.6279-6284.1997
    • (1997) J. Bacteriol , vol.179 , pp. 6279-6284
    • Kapteyn, J.C.1    Ram, A.F.2    Groos, E.M.3    Kollar, R.4    Montijn, R.C.5    Van Den Ende, H.6
  • 20
    • 40349102094 scopus 로고    scopus 로고
    • Mucosal damage and neutropenia are required for Candida albicans dissemination
    • Koh, A. Y., Köhler, J. R., Coggshall, K. T., Van Rooijen, N., and Pier, G. B. (2008). Mucosal damage and neutropenia are required for Candida albicans dissemination. PLoS Pathog. 4:e35. doi: 10.1371/journal.ppat.0040035
    • (2008) PLoS Pathog , vol.4
    • Koh, A.Y.1    Köhler, J.R.2    Coggshall, K.T.3    Van Rooijen, N.4    Pier, G.B.5
  • 21
    • 84949192205 scopus 로고    scopus 로고
    • Gene essentiality is a quantitative property linked to cellular evolvability
    • Liu, G., Yong, M. Y., Yurieva, M., Srinivasan, K. G., Liu, J., Lim, J. S., et al. (2015). Gene essentiality is a quantitative property linked to cellular evolvability. Cell 163, 1388-1399. doi: 10.1016/j.cell.2015.10.069
    • (2015) Cell , vol.163 , pp. 1388-1399
    • Liu, G.1    Yong, M.Y.2    Yurieva, M.3    Srinivasan, K.G.4    Liu, J.5    Lim, J.S.6
  • 22
    • 84893702179 scopus 로고    scopus 로고
    • Novel structural features in Candida albicans hyphal glucan provide a basis for differential innate immune recognition of hyphae versus yeast
    • Lowman, D. W., Greene, R. R., Bearden, D. W., Kruppa, M. D., Pottier, M., Monteiro, M. A., et al. (2014). Novel structural features in Candida albicans hyphal glucan provide a basis for differential innate immune recognition of hyphae versus yeast. J. Biol. Chem. 289, 3432-3443. doi: 10.1074/jbc.M113.529131
    • (2014) J. Biol. Chem , vol.289 , pp. 3432-3443
    • Lowman, D.W.1    Greene, R.R.2    Bearden, D.W.3    Kruppa, M.D.4    Pottier, M.5    Monteiro, M.A.6
  • 23
    • 79957921817 scopus 로고    scopus 로고
    • 'Candida infections and modelling disease,'
    • eds. R. Ashbee and M. E. Bignell (Berlin; Heidelberg: Springer Berlin Heidelberg)
    • Maccallum, D. M. (2010). "Candida infections and modelling disease," in Pathogenic Yeasts, eds R. Ashbee and M. E. Bignell (Berlin; Heidelberg: Springer Berlin Heidelberg), 41-67.
    • (2010) Pathogenic Yeasts , pp. 41-67
    • Maccallum, D.M.1
  • 24
    • 84876848564 scopus 로고    scopus 로고
    • Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1
    • Marakalala, M. J., Vautier, S., Potrykus, J., Walker, L. A., Shepardson, K. M., Hopke, A., et al. (2013). Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1. PLoS Pathog. 9:e1003315. doi: 10.1371/journal.ppat.1003315
    • (2013) PLoS Pathog , vol.9
    • Marakalala, M.J.1    Vautier, S.2    Potrykus, J.3    Walker, L.A.4    Shepardson, K.M.5    Hopke, A.6
  • 25
    • 14444283595 scopus 로고    scopus 로고
    • Cloning of the Candida albicans homolog of Saccharomyces cerevisiae GSC1/FKS1 and its involvement in beta-1,3-glucan synthesis
    • Mio, T., Adachi-Shimizu, M., Tachibana, Y., Tabuchi, H., Inoue, S. B., Yabe, T., et al. (1997). Cloning of the Candida albicans homolog of Saccharomyces cerevisiae GSC1/FKS1 and its involvement in beta-1,3-glucan synthesis. J. Bacteriol. 179, 4096-4105. doi: 10.1128/jb.179.13.4096-4105.1997
    • (1997) J. Bacteriol , vol.179 , pp. 4096-4105
    • Mio, T.1    Adachi-Shimizu, M.2    Tachibana, Y.3    Tabuchi, H.4    Inoue, S.B.5    Yabe, T.6
  • 27
    • 79955611207 scopus 로고    scopus 로고
    • Recognition and blocking of innate immunity cells by Candida albicans chitin
    • Mora-Montes, H. M., Netea, M. G., Ferwerda, G., Lenardon, M. D., Brown, G. D., Mistry, A. R., et al. (2011). Recognition and blocking of innate immunity cells by Candida albicans chitin. Infect. Immun. 79, 1961-1970. doi: 10.1128/IAI.01282-10
    • (2011) Infect. Immun , vol.79 , pp. 1961-1970
    • Mora-Montes, H.M.1    Netea, M.G.2    Ferwerda, G.3    Lenardon, M.D.4    Brown, G.D.5    Mistry, A.R.6
  • 28
    • 19944431369 scopus 로고    scopus 로고
    • Mnt1p and Mnt2p of Candida albicans are partially redundant alpha-1,2-mannosyltransferases that participate in O-linked mannosylation and are required for adhesion and virulence
    • Munro, C. A., Bates, S., Buurman, E. T., Hughes, H. B., Maccallum, D. M., Bertram, G., et al. (2005). Mnt1p and Mnt2p of Candida albicans are partially redundant alpha-1,2-mannosyltransferases that participate in O-linked mannosylation and are required for adhesion and virulence. J. Biol. Chem. 280, 1051-1060. doi: 10.1074/jbc.M411413200
    • (2005) J. Biol. Chem , vol.280 , pp. 1051-1060
    • Munro, C.A.1    Bates, S.2    Buurman, E.T.3    Hughes, H.B.4    Maccallum, D.M.5    Bertram, G.6
  • 29
    • 37349015349 scopus 로고    scopus 로고
    • An integrated model of the recognition of Candida albicans by the innate immune system
    • Netea, M. G., Brown, G. D., Kullberg, B. J., and Gow, N. A. (2008). An integrated model of the recognition of Candida albicans by the innate immune system. Nat. Rev. Microbiol. 6, 67-78. doi: 10.1038/nrmicro1815
    • (2008) Nat. Rev. Microbiol , vol.6 , pp. 67-78
    • Netea, M.G.1    Brown, G.D.2    Kullberg, B.J.3    Gow, N.A.4
  • 30
    • 0035893122 scopus 로고    scopus 로고
    • Revisiting the source of candidemia: skin or gut?
    • Nucci, M., and Anaissie, E. (2001). Revisiting the source of candidemia: skin or gut? Clin. Infect. Dis. 33, 1959-1967. doi: 10.1086/323759
    • (2001) Clin Infect. Dis , vol.33 , pp. 1959-1967
    • Nucci, M.1    Anaissie, E.2
  • 31
    • 84883434044 scopus 로고    scopus 로고
    • Passage through the mammalian gut triggers a phenotypic switch that promotes Candida albicans commensalism
    • Pande, K., Chen, C., and Noble, S. M. (2013). Passage through the mammalian gut triggers a phenotypic switch that promotes Candida albicans commensalism. Nat. Genet. 45, 1088-1091. doi: 10.1038/ng.2710
    • (2013) Nat. Genet , vol.45 , pp. 1088-1091
    • Pande, K.1    Chen, C.2    Noble, S.M.3
  • 32
    • 78149423336 scopus 로고    scopus 로고
    • Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast
    • Pavelka, N., Rancati, G., Zhu, J., Bradford, W. D., Saraf, A., Florens, L., et al. (2010). Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast. Nature 468, 321-325. doi: 10.1038/nature09529
    • (2010) Nature , vol.468 , pp. 321-325
    • Pavelka, N.1    Rancati, G.2    Zhu, J.3    Bradford, W.D.4    Saraf, A.5    Florens, L.6
  • 33
    • 33846466508 scopus 로고    scopus 로고
    • Epidemiology of invasive candidiasis: a persistent public health problem
    • Pfaller, M. A., and Diekema, D. J. (2007). Epidemiology of invasive candidiasis: a persistent public health problem. Clin. Microbiol. Rev. 20, 133-163. doi: 10.1128/CMR.00029-06
    • (2007) Clin. Microbiol. Rev , vol.20 , pp. 133-163
    • Pfaller, M.A.1    Diekema, D.J.2
  • 34
    • 84900344166 scopus 로고    scopus 로고
    • The HOG pathway is critical for the colonization of the mouse gastrointestinal tract by Candida albicans
    • Prieto, D., Román, E., Correia, I., and Pla, J. (2014). The HOG pathway is critical for the colonization of the mouse gastrointestinal tract by Candida albicans. PLoS ONE 9:e87128. doi: 10.1371/journal.pone.0087128
    • (2014) PLoS ONE , vol.9
    • Prieto, D.1    Román, E.2    Correia, I.3    Pla, J.4
  • 35
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K. S., Manichanh, C., et al. (2010). A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464, 59-65. doi: 10.1038/nature08821
    • (2010) Nature , vol.464 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3    Arumugam, M.4    Burgdorf, K.S.5    Manichanh, C.6
  • 36
    • 84865119423 scopus 로고    scopus 로고
    • Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes
    • Quintin, J., Saeed, S., Martens, J. H., Giamarellos-Bourboulis, E. J., Ifrim, D. C., Logie, C., et al. (2012). Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes. Cell Host Microbe 12, 223-232. doi: 10.1016/j.chom.2012.06.006
    • (2012) Cell Host Microbe , vol.12 , pp. 223-232
    • Quintin, J.1    Saeed, S.2    Martens, J.H.3    Giamarellos-Bourboulis, E.J.4    Ifrim, D.C.5    Logie, C.6
  • 37
    • 56349088536 scopus 로고    scopus 로고
    • Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motor
    • Rancati, G., Pavelka, N., Fleharty, B., Noll, A., Trimble, R., Walton, K., et al. (2008). Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motor. Cell 135, 879-893. doi: 10.1016/j.cell.2008.09.039
    • (2008) Cell , vol.135 , pp. 879-893
    • Rancati, G.1    Pavelka, N.2    Fleharty, B.3    Noll, A.4    Trimble, R.5    Walton, K.6
  • 38
    • 84858129683 scopus 로고    scopus 로고
    • Gene deletion in Candida albicans wild-type strains using the SAT1-flipping strategy
    • Sasse, C., and Morschhäuser, J. (2012). Gene deletion in Candida albicans wild-type strains using the SAT1-flipping strategy. Methods Mol. Biol. 845, 3-17. doi: 10.1007/978-1-61779-539-8_1
    • (2012) Methods Mol. Biol , vol.845 , pp. 3-17
    • Sasse, C.1    Morschhäuser, J.2
  • 39
    • 77956858683 scopus 로고    scopus 로고
    • Genomic plasticity of the human fungal pathogen Candida albicans
    • Selmecki, A., Forche, A., and Berman, J. (2010). Genomic plasticity of the human fungal pathogen Candida albicans. Eukaryot Cell 9, 991-1008. doi: 10.1128/EC.00060-10
    • (2010) Eukaryot Cell , vol.9 , pp. 991-1008
    • Selmecki, A.1    Forche, A.2    Berman, J.3
  • 40
    • 84988874574 scopus 로고    scopus 로고
    • Age and gender affect the composition of fungal population of the human gastrointestinal tract
    • Strati, F., Di Paola, M., Stefanini, I., Albanese, D., Rizzetto, L., Lionetti, P., et al. (2016). Age and gender affect the composition of fungal population of the human gastrointestinal tract. Front. Microbiol. 7:1227. doi: 10.3389/fmicb.2016.01227
    • (2016) Front. Microbiol , vol.7 , pp. 1227
    • Strati, F.1    Di Paola, M.2    Stefanini, I.3    Albanese, D.4    Rizzetto, L.5    Lionetti, P.6
  • 41
    • 33846962860 scopus 로고    scopus 로고
    • Dectin-1 is required for beta-glucan recognition and control of fungal infection
    • Taylor, P. R., Tsoni, S. V., Willment, J. A., Dennehy, K. M., Rosas, M., Findon, H., et al. (2007). Dectin-1 is required for beta-glucan recognition and control of fungal infection. Nat. Immunol. 8, 31-38. doi: 10.1038/ni1408
    • (2007) Nat. Immunol , vol.8 , pp. 31-38
    • Taylor, P.R.1    Tsoni, S.V.2    Willment, J.A.3    Dennehy, K.M.4    Rosas, M.5    Findon, H.6
  • 42
    • 84870851345 scopus 로고    scopus 로고
    • Dectin-1 is not required for controlling Candida albicans colonization of the gastrointestinal tract
    • Vautier, S., Drummond, R. A., Redelinghuys, P., Murray, G. I., Maccallum, D. M., and Brown, G. D. (2012). Dectin-1 is not required for controlling Candida albicans colonization of the gastrointestinal tract. Infect. Immun. 80, 4216-4222. doi: 10.1128/IAI.00559-12
    • (2012) Infect. Immun , vol.80 , pp. 4216-4222
    • Vautier, S.1    Drummond, R.A.2    Redelinghuys, P.3    Murray, G.I.4    Maccallum, D.M.5    Brown, G.D.6
  • 43
    • 84919683994 scopus 로고    scopus 로고
    • Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant
    • Wartenberg, A., Linde, J., Martin, R., Schreiner, M., Horn, F., Jacobsen, I. D., et al. (2014). Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant. PLoS Genet. 10:e1004824. doi: 10.1371/journal.pgen.1004824
    • (2014) PLoS Genet , vol.10
    • Wartenberg, A.1    Linde, J.2    Martin, R.3    Schreiner, M.4    Horn, F.5    Jacobsen, I.D.6
  • 44
    • 58149269544 scopus 로고    scopus 로고
    • Dynamic, morphotype-specific Candida albicans beta-glucan exposure during infection and drug treatment
    • Wheeler, R. T., Kombe, D., Agarwala, S. D., and Fink, G. R. (2008). Dynamic, morphotype-specific Candida albicans beta-glucan exposure during infection and drug treatment. PLoS Pathog. 4:e1000227. doi: 10.1371/journal.ppat.1000227
    • (2008) PLoS Pathog , vol.4
    • Wheeler, R.T.1    Kombe, D.2    Agarwala, S.D.3    Fink, G.R.4


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