-
1
-
-
54149090275
-
The Global Burden of Disease
-
WHO update Geneva update
-
1 World Health Organization (WHO). The Global Burden of Disease. 2004 update, WHO, Geneva.
-
(2004)
-
-
-
2
-
-
84873956600
-
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
-
2 Vestbo, J., Hurd, S.S., Agusti, A.G., et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 187 (2013), 347–365, 10.1164/rccm.201204-0596PP.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 347-365
-
-
Vestbo, J.1
Hurd, S.S.2
Agusti, A.G.3
-
3
-
-
38449085224
-
Role of N-acetylcysteine in the management of COPD
-
3 Sadowska, A.M., Verbraecken, J., Darquennes, K., et al. Role of N-acetylcysteine in the management of COPD. Int J Chron Obstruct Pulmon Dis 1 (2006), 425–434.
-
(2006)
Int J Chron Obstruct Pulmon Dis
, vol.1
, pp. 425-434
-
-
Sadowska, A.M.1
Verbraecken, J.2
Darquennes, K.3
-
4
-
-
34548107307
-
Effect of oral N-acetylcysteine in COPD—a randomised controlled trial
-
4 Bachh, Arshad Altaf, Bhargava, Rakesh, Shah, Naveed Nazir, et al. Effect of oral N-acetylcysteine in COPD—a randomised controlled trial. JK Pract 14 (2007), 12–16.
-
(2007)
JK Pract
, vol.14
, pp. 12-16
-
-
Bachh, A.A.1
Bhargava, R.2
Shah, N.N.3
-
5
-
-
0032759974
-
N-acetylcysteine reduces the exacerbation rate in patients with moderate to severe COPD
-
5 Pela, R., Calcagni, A.M., Subiaco, S., et al. N-acetylcysteine reduces the exacerbation rate in patients with moderate to severe COPD. Respiration 66 (1999), 495–500.
-
(1999)
Respiration
, vol.66
, pp. 495-500
-
-
Pela, R.1
Calcagni, A.M.2
Subiaco, S.3
-
6
-
-
84895803870
-
Twice daily N-acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomised, double-blind placebo-controlled trial
-
6 Zheng, J.P., Wen, F.Q., Bai, C.X., et al. Twice daily N-acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomised, double-blind placebo-controlled trial. Lancet Respir Med 2 (2014), 187–194, 10.1016/s2213-2600(13)70286-8.
-
(2014)
Lancet Respir Med
, vol.2
, pp. 187-194
-
-
Zheng, J.P.1
Wen, F.Q.2
Bai, C.X.3
-
7
-
-
0028040727
-
Orally administered N-acetylcysteine may improve general well-being in patients with mild chronic bronchitis
-
7 Hansen, N.C., Skriver, A., Brorsen-Riis, L., et al. Orally administered N-acetylcysteine may improve general well-being in patients with mild chronic bronchitis. Respir Med 88 (1994), 531–535.
-
(1994)
Respir Med
, vol.88
, pp. 531-535
-
-
Hansen, N.C.1
Skriver, A.2
Brorsen-Riis, L.3
-
8
-
-
84940663022
-
Influence of N-acetylcysteine on chronic bronchitis or COPD exacerbations: a meta-analysis
-
8 Cazzola, M., Calzetta, L., Page, C., et al. Influence of N-acetylcysteine on chronic bronchitis or COPD exacerbations: a meta-analysis. Eur Respir Rev 24 (2015), 451–461, 10.1183/16000617.00002215.
-
(2015)
Eur Respir Rev
, vol.24
, pp. 451-461
-
-
Cazzola, M.1
Calzetta, L.2
Page, C.3
-
9
-
-
84900801448
-
Effect of high/low dose N-acetylcysteine on chronic obstructive pulmonary disease: a systematic review and meta-analysis
-
9 Shen, Y., Cai, W., Lei, S., et al. Effect of high/low dose N-acetylcysteine on chronic obstructive pulmonary disease: a systematic review and meta-analysis. COPD 11 (2014), 351–358, 10.3109/15412555.2013.858315.
-
(2014)
COPD
, vol.11
, pp. 351-358
-
-
Shen, Y.1
Cai, W.2
Lei, S.3
-
10
-
-
84861558523
-
Nutritional support in chronic obstructive pulmonary disease: a systematic review and meta-analysis
-
10 Collins, P.F., Stratton, R.J., Elia, M., Nutritional support in chronic obstructive pulmonary disease: a systematic review and meta-analysis. Am J Clin Nutr 95 (2012), 1385–1395, 10.3945/ajcn.111.023499.
-
(2012)
Am J Clin Nutr
, vol.95
, pp. 1385-1395
-
-
Collins, P.F.1
Stratton, R.J.2
Elia, M.3
-
11
-
-
0029914622
-
Assessing the quality of reports of randomized clinical trials: is blinding necessary?
-
11 Jadad, A.R., Moore, R.A., Carroll, D., et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary?. Control Clin Trials 17 (1996), 1–12.
-
(1996)
Control Clin Trials
, vol.17
, pp. 1-12
-
-
Jadad, A.R.1
Moore, R.A.2
Carroll, D.3
-
12
-
-
1842552109
-
Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper
-
12 Celli, B.R., MacNee, W., Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J 23 (2004), 932–946.
-
(2004)
Eur Respir J
, vol.23
, pp. 932-946
-
-
Celli, B.R.1
MacNee, W.2
-
13
-
-
0037764092
-
COPD exacerbations: definitions and classifications
-
13 Burge, S., Wedzicha, J.A., COPD exacerbations: definitions and classifications. Eur Respir J Suppl 41 (2003), 46s–53s.
-
(2003)
Eur Respir J Suppl
, vol.41
, pp. 46s-53s
-
-
Burge, S.1
Wedzicha, J.A.2
-
14
-
-
84880047842
-
High-dose N-acetylcysteine in stable COPD: the 1-year, double-blind, randomized, placebo-controlled HIACE study
-
14 Tse, H.N., Raiteri, L., Wong, K.Y., et al. High-dose N-acetylcysteine in stable COPD: the 1-year, double-blind, randomized, placebo-controlled HIACE study. Chest 144 (2013), 106–118, 10.1378/chest.12-2357.
-
(2013)
Chest
, vol.144
, pp. 106-118
-
-
Tse, H.N.1
Raiteri, L.2
Wong, K.Y.3
-
15
-
-
0022414065
-
Oral N-acetylcysteine and exacerbation rates in patients with chronic bronchitis and severe airways obstruction. British Thoracic Society Research Committee
-
15 McGavin, C.R., Macfarlane, J.T., Prescott, R.J., et al. Oral N-acetylcysteine and exacerbation rates in patients with chronic bronchitis and severe airways obstruction. British Thoracic Society Research Committee. Thorax 40 (1985), 832–835.
-
(1985)
Thorax
, vol.40
, pp. 832-835
-
-
McGavin, C.R.1
Macfarlane, J.T.2
Prescott, R.J.3
-
16
-
-
0017111053
-
A controlled trial of intermittent oral acetylcysteine in the long-term treatment of chronic bronchitis
-
16 Grassi, C., Morandini, G.C., A controlled trial of intermittent oral acetylcysteine in the long-term treatment of chronic bronchitis. Eur J Clin Pharmacol 09 (1976), 393–396.
-
(1976)
Eur J Clin Pharmacol
, vol.9
, pp. 393-396
-
-
Grassi, C.1
Morandini, G.C.2
-
17
-
-
0023912569
-
Reduction in days of illness after long-term treatment with N-acetylcysteine controlled-release tablets in patients with chronic bronchitis
-
17 Rasmussen, J.B., Glennow, C., Reduction in days of illness after long-term treatment with N-acetylcysteine controlled-release tablets in patients with chronic bronchitis. Eur Respir J 1 (1988), 351–355.
-
(1988)
Eur Respir J
, vol.1
, pp. 351-355
-
-
Rasmussen, J.B.1
Glennow, C.2
-
18
-
-
60649103762
-
Fluticasone and N-acetylcysteine in primary care patients with COPD or chronic bronchitis
-
18 Schermer, T., Chavannes, N., Dekhuijzen, R., et al. Fluticasone and N-acetylcysteine in primary care patients with COPD or chronic bronchitis. Respir Med 103 (2009), 542–551, 10.1016/j.rmed.2008.11.003.
-
(2009)
Respir Med
, vol.103
, pp. 542-551
-
-
Schermer, T.1
Chavannes, N.2
Dekhuijzen, R.3
-
19
-
-
20944433417
-
Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised placebo-controlled trial
-
19 Decramer, M., Rutten-van Molken, M., Dekhuijzen, P.N., et al. Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised placebo-controlled trial. Lancet 365 (2005), 1552–1560, 10.1016/s0140-6736(05)66456-2.
-
(2005)
Lancet
, vol.365
, pp. 1552-1560
-
-
Decramer, M.1
Rutten-van Molken, M.2
Dekhuijzen, P.N.3
-
20
-
-
68849103501
-
Effect of N-acetylcysteine on air trapping in COPD: a randomized placebo-controlled study
-
20 Stav, D., Raz, M., Effect of N-acetylcysteine on air trapping in COPD: a randomized placebo-controlled study. Chest 136 (2009), 381–386, 10.1378/chest.09-0421.
-
(2009)
Chest
, vol.136
, pp. 381-386
-
-
Stav, D.1
Raz, M.2
-
21
-
-
84888172067
-
Effect of high-dose N-acetylcysteine on airway geometry, inflammation, and oxidative stress in COPD patients
-
21 De Backer, J., Vos, W., Van Holsbeke, C., et al. Effect of high-dose N-acetylcysteine on airway geometry, inflammation, and oxidative stress in COPD patients. Int J Chron Obstruct Pulmon Dis 8 (2013), 569–579, 10.2147/copd.s49307.
-
(2013)
Int J Chron Obstruct Pulmon Dis
, vol.8
, pp. 569-579
-
-
De Backer, J.1
Vos, W.2
Van Holsbeke, C.3
-
22
-
-
84875866752
-
High-dose N-acetylcysteine in the prevention of COPD exacerbations: rationale and design of the PANTHEON Study
-
22 Zheng, J.P., Wen, F.Q., Bai, C.X., et al. High-dose N-acetylcysteine in the prevention of COPD exacerbations: rationale and design of the PANTHEON Study. COPD 10 (2013), 164–171, 10.3109/15412555.2012.732628.
-
(2013)
COPD
, vol.10
, pp. 164-171
-
-
Zheng, J.P.1
Wen, F.Q.2
Bai, C.X.3
-
23
-
-
1842481121
-
Antioxidant properties of N-acetylcysteine: their relevance in relation to chronic obstructive pulmonary disease
-
23 Dekhuijzen, P.N., Antioxidant properties of N-acetylcysteine: their relevance in relation to chronic obstructive pulmonary disease. Eur Respir J 23 (2004), 629–636.
-
(2004)
Eur Respir J
, vol.23
, pp. 629-636
-
-
Dekhuijzen, P.N.1
-
24
-
-
58149335378
-
The effect of different treatment modalities on oxidative stress in COPD
-
24 Kuleci, S., Hanta, I., Kocabas, A., et al. The effect of different treatment modalities on oxidative stress in COPD. Adv Ther 25 (2008), 710–717, 10.1007/s12325-008-0064-4.
-
(2008)
Adv Ther
, vol.25
, pp. 710-717
-
-
Kuleci, S.1
Hanta, I.2
Kocabas, A.3
-
25
-
-
85014060421
-
The effect of N-Acetylcysteine on oxidative stress and pulmonary function in elderly patients with COPD
-
25 Li, J.H., He, H., Yu, W., et al. The effect of N-Acetylcysteine on oxidative stress and pulmonary function in elderly patients with COPD. J Yunyang Med Coll, 2008, 247–249.
-
(2008)
J Yunyang Med Coll
, pp. 247-249
-
-
Li, J.H.1
He, H.2
Yu, W.3
-
26
-
-
0034942666
-
Long-term administration of N-acetylcysteine decreases hydrogen peroxide exhalation in subjects with chronic obstructive pulmonary disease
-
26 Kasielski, M., Nowak, D., Long-term administration of N-acetylcysteine decreases hydrogen peroxide exhalation in subjects with chronic obstructive pulmonary disease. Respir Med 95 (2001), 448–456, 10.1053/rmed.2001.1066.
-
(2001)
Respir Med
, vol.95
, pp. 448-456
-
-
Kasielski, M.1
Nowak, D.2
-
27
-
-
10644250916
-
Long-term oral n-acetylcysteine reduces exhaled hydrogen peroxide in stable COPD
-
27 De Benedetto, F., Aceto, A., Dragani, B., et al. Long-term oral n-acetylcysteine reduces exhaled hydrogen peroxide in stable COPD. Pulm Pharmacol Ther 18 (2005), 41–47, 10.1016/j.pupt.2004.09.030.
-
(2005)
Pulm Pharmacol Ther
, vol.18
, pp. 41-47
-
-
De Benedetto, F.1
Aceto, A.2
Dragani, B.3
-
28
-
-
22544436397
-
High-dose N-acetylcysteine in patients with exacerbations of chronic obstructive pulmonary disease
-
28 Zuin, R., Palamidese, A., Negrin, R., et al. High-dose N-acetylcysteine in patients with exacerbations of chronic obstructive pulmonary disease. Clin Drug Investig 25 (2005), 401–408.
-
(2005)
Clin Drug Investig
, vol.25
, pp. 401-408
-
-
Zuin, R.1
Palamidese, A.2
Negrin, R.3
-
29
-
-
31344465272
-
New developments in the treatment of COPD: comparing the effects of inhaled corticosteroids and N-acetylcysteine
-
29 van Overveld, F.J., Demkow, U., Gorecka, D., et al. New developments in the treatment of COPD: comparing the effects of inhaled corticosteroids and N-acetylcysteine. J Physiol Pharmacol 56:suppl 4 (2005), 135–142.
-
(2005)
J Physiol Pharmacol
, vol.56
, pp. 135-142
-
-
van Overveld, F.J.1
Demkow, U.2
Gorecka, D.3
-
30
-
-
0028266997
-
The intrabronchial microbial flora in chronic bronchitis patients: a target for N-acetylcysteine therapy?
-
30 Riise, G.C., Larsson, S., Larsson, P., et al. The intrabronchial microbial flora in chronic bronchitis patients: a target for N-acetylcysteine therapy?. Eur Respir J 7 (1994), 94–101.
-
(1994)
Eur Respir J
, vol.7
, pp. 94-101
-
-
Riise, G.C.1
Larsson, S.2
Larsson, P.3
-
31
-
-
33750484015
-
Antioxidant and anti-inflammatory efficacy of NAC in the treatment of COPD: discordant in vitro and in vivo dose-effects: a review
-
31 Sadowska, A.M., Manuel, Y.K.B., De Backer, W.A., Antioxidant and anti-inflammatory efficacy of NAC in the treatment of COPD: discordant in vitro and in vivo dose-effects: a review. Pulm Pharmacol Ther 20 (2007), 9–22, 10.1016/j.pupt.2005.12.007.
-
(2007)
Pulm Pharmacol Ther
, vol.20
, pp. 9-22
-
-
Sadowska, A.M.1
Manuel, Y.K.B.2
De Backer, W.A.3
|