Reprogramming to resist: Prostate cancer cells alter identity to resist therapy

Science

Volumn 355, Issue 6320, 2017, Pages 29-30

  Kelly, Kathleen ^a   Balk, Steven P ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABIRATERONE; ANDROSTANOLONE; DNA METHYLTRANSFERASE 1; ENZALUTAMIDE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53; RETINOBLASTOMA BINDING PROTEIN 1; SYNAPTOPHYSIN; TESTOSTERONE; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR SOX2;

CANCER; CELLS AND CELL COMPONENTS; DISEASE TREATMENT; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC MARKER; TESTOSTERONE;

ADENOCARCINOMA IN SITU; ANDROGEN SYNTHESIS; CANCER CELL; CANCER GROWTH; CANCER RESISTANCE; CANCER THERAPY; CASTRATION RESISTANT PROSTATE CANCER; CELL PLASTICITY; DNA METHYLATION; GENE EXPRESSION; GENE SILENCING; HUMAN; INDUCED PLURIPOTENT STEM CELL; LNCAP CELL LINE; NEUROENDOCRINE DISEASE; NONHUMAN; NUCLEAR REPROGRAMMING; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROSTATE CANCER; REVIEW; RNA SEQUENCE; TUMOR RECURRENCE;

CELLULAR REPROGRAMMING; HUMANS; INDUCED PLURIPOTENT STEM CELLS;

EID: 85009266752     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aam5355     Document Type: Review

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