Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy

Cell Reports

Volumn 18, Issue 2, 2017, Pages 571-582

  Cho, Gun Sik ^a   Lee, Dong I ^a   Tampakakis, Emmanouil ^a   Murphy, Sean ^a   Andersen, Peter ^a   Uosaki, Hideki ^a   Chelko, Stephen ^a   Chakir, Khalid ^a   Hong, Ingie ^a   Seo, Kinya ^a   Chen, Huei Sheng Vincent ^b   Chen, Xiongwen ^c   Basso, Cristina ^c,d   Houser, Steven R ^c   Tomaselli, Gordon F ^a   O'Rourke, Brian ^a   Judge, Daniel P ^a   Kass, David A ^a   Kwon, Chulan ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BURNHAM INSTITUTE   (United States)

^c TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PADOVA   (Italy)

Author keywords

ARVC; calcium transient; cardiac progenitor; cardiomyocyte; cardiomyopathy; disease modeling; iPS; maturation; neonatal; sarcomere shortening; T tubule

Indexed keywords

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE CELL; CARDIOMYOPATHY; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CELL STRUCTURE; CELL TRANSPLANTATION; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRIAL BIOGENESIS; MOUSE; NEWBORN; NONHUMAN; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RAT; RNA SEQUENCE; SEQUENCE ANALYSIS; AGING; ANIMAL; CELL SHAPE; CYTOLOGY; DISEASE MODEL; GENE EXPRESSION REGULATION; HEART CONTRACTION; INDUCED PLURIPOTENT STEM CELL; METABOLISM; MOUSE EMBRYONIC STEM CELL; PATHOLOGY; PATHOPHYSIOLOGY; SINGLE CELL ANALYSIS; STEM CELL TRANSPLANTATION; ULTRASTRUCTURE;

CALCIUM;

AGING; ANIMALS; ANIMALS, NEWBORN; CALCIUM; CARDIOMYOPATHIES; CELL DIFFERENTIATION; CELL SHAPE; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; MOUSE EMBRYONIC STEM CELLS; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PHENOTYPE; PLURIPOTENT STEM CELLS; SEQUENCE ANALYSIS, RNA; SINGLE-CELL ANALYSIS; STEM CELL TRANSPLANTATION;

EID: 85009186327     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.12.040     Document Type: Article

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