F344-rnu/rnu Athymic Rats: Breeding Performance and Acceptance of Subcutaneous and Intracranial Xenografts at Different Ages

Laboratory Animal Science

Volumn 47, Issue 5, 1997, Pages 549-553

  Liang, San Chi ^a   Shinn Zong, Lin ^b   Jen Fan, Yu ^a   Shu Fen, Wu ^a   Shwun De, Wang ^b   Jiang Chuan, Liu ^b  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREEDING; CANCER GRAFT; FEMALE; FERTILITY; HETEROZYGOSITY; HOMOZYGOSITY; MALE; MALIGNANT NEOPLASTIC DISEASE; NONHUMAN; PERFORMANCE; RAT; XENOGRAFT;

ANIMALS; ANIMALS, NEWBORN; BRAIN; BREEDING; FEMALE; FERTILITY; HELA CELLS; HUMANS; LITTER SIZE; MALE; MICE; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; RATS; RATS, INBRED F344; RATS, NUDE; SKIN; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0031421884     PISSN: 00236764     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Festing, M. F. W., D. May, T. A. Connors, et al. 1978. An athymic nude mutation in the rat. Nature 274:365-366.
2. Schuurman, H-J., H. P. Hougen, and H. van Loveren. 1992. The rnu (Rowett nude) and rnu N (nznu, New Zealand nude) rat: an update. ILAR News 34:3-12.
3. Festing, M. F. W. 1981. Athymic nude rats, p. 267-283. In M. E. Gershwin and B. Merchant (ed.), Immunological defects in laboratory animals. Plenum Press, New York.
4. Hedrich, H. J. 1990. Genetic monitoring of inbred strains of rats. A manual on colony management basic monitoring technique, and genetic variants of the laboratory rat, p. 377-380. Gustav Fisher Verlag, Stuttgart.
5. Vos, J. G., J. M. Berkvens, and B. C. Kruijt. 1980. The athymic nude rat. I. Morphology of lymphoid and endocrine organs. Clin. Immunol. Immunopathol. 15:213-228.
6. Hedrich, H. J., K. Wonigeit, and R. Schwinzer. 1987. In vivo alloreactivity and xenoreactivity of athymic nude rats. Transplant. Proc. 19:3199-3202.
7. Maruo, L., Y. Ueyama, Y. Kuwahara, et al. 1982. Human tumor xenografts in athymic rats and their age dependence. Br. J. Cancer 45:786-789.
8. Salomon, J-C., and J. Fogh. 1982. The nude rat, p. 229-245. In J. Fogh and B. C. Giovanella (ed.), The nude mouse in experimental and clinical research, vol. 2. Academic Press, Inc., New York.
9. Howard, M. A., III, R. G. Dacey, and R. Winn. 1988. Brain xenografts: the effect of cyclosporin A on graft survival. J. Neurosci. 69:121-126.
10. Pace, M. T., T. L. Solvis, J. K. Kelly, et al. 1995. Cyclosporin A toxicity: MRI appearance of the brain. Pediatr. Radiol. 25:180-183.
11. Schwinzer, R., H. J. Hedrich, and K. Wonigeit. 1987. Development of T-like cells in athymic Rowett nude rats (rnu / rnu). Transplant. Proc. 19:3131-3133.
12. Schuurman, H-J. 1992. Comparative evaluation of congenitally athymic and euthymic rats bred and maintained at different institutes. II. Athymic rats. J. Exp. Anim. Sci. 35:33-48.
13. Markowitz, D., S. Goff, and A. Bank. 1988. Construction and use of safe and efficient amphotropic packaging cell line. Virology 167:400-406.
14. Ediger, R., and B. C. Giovanella. 1978. Current knowledge of breeding and mass production of the nude mouse, p. 15-27. In J. Fogh and B. C. Giovanella (ed.), The nude mouse in experimental and clinical research. Academic Press, Inc., New York.
15. Lotzova, E., C. A. Savary, D. A. Stringfellow, et al. 1984. Analysis of natural killer cell activity in random-bred Rowett athymic rats. Exp. Cell Biol. 52:53-59.
16. Lyon, M. F., and A. G. Searle. 1989. Genetic variants and strains of the laboratory mouse, 2nd ed. Oxford University Press, Oxford.
17. Head, J. R., and W. S. T. Griffin. 1985. Functional capacity of solid tissue transplants in the brain: evidence for immunological privilege. Proc. Royal Soc. London Ser. B 224:375-387.
18. Rao, K., R. D. Lund. H. W. Kunz, et al. 1989. The role of MHC and non-MHC antigens in the rejection of intracerebral allogeneic neural grafts. Transplantation 48:1018-1021.